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Select item 48899591.

Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex

Jinhu Yin, Bingbing Wan, Jaya Sarkar, Kent Horvath, Jian Wu, Yong Chen, Guangjuan Cheng, Ke Wan, Peiju Chin, Ming Lei, Yie Liu

Nucleic Acids Res. 2016 Jun 2; 44(10): 4871–4880. Published online 2016 Apr 29. doi: 10.1093/nar/gkw354

PMCID:: PMC4889959

Article PDF–2.8M

Select item 48890102.

Disruption of SLX4-MUS81 Function Increases the Relative Biological Effectiveness of Proton Radiation

Qi Liu, Tracy S. A. Underwood, Jong Kung, Meng Wang, Hsiao-Ming Lu, Harald Paganetti, Kathryn D. Held, Theodore S. Hong, Jason A. Efstathiou, Henning Willers

Int J Radiat Oncol Biol Phys. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2016 May 1; 95(1): 78–85. Published online 2016 Feb 1. doi: 10.1016/j.ijrobp.2016.01.046

PMCID:: PMC4889010

Article PDF–1.3M

Select item 41453673.

Nuclease Delivery: Versatile Functions of SLX4/FANCP in Genome Maintenance

Yonghwan Kim

Mol Cells. 2014 Aug 31; 37(8): 569–574. Published online 2014 Jun 18. doi: 10.14348/molcells.2014.0118

PMCID:: PMC4145367

Article PDF–905K

Select item 37226784.

Low prevalence of SLX4 loss-of-function mutations in non-BRCA1/2 breast and/or ovarian cancer families

Gorka Ruiz de Garibay, Avellaneda Díaz, Belén Gaviña, Atocha Romero, Pilar Garre, Ana Vega, Ana Blanco, Alicia Tosar, Orland Díez, Pedro Pérez-Segura, Eduardo Díaz-Rubio, Trinidad Caldés, Miguel de la Hoya

Eur J Hum Genet. 2013 Aug; 21(8): 883–886. Published online 2012 Dec 5. doi: 10.1038/ejhg.2012.268

PMCID:: PMC3722678

Article PDF–393K

Select item 36941105.

Assessment of SLX4 Mutations in Hereditary Breast Cancers

Sohela Shah, Yonghwan Kim, Irina Ostrovnaya, Rajmohan Murali, Kasmintan A. Schrader, Francis P. Lach, Kara Sarrel, Rohini Rau-Murthy, Nichole Hansen, Liyng Zhang, Tomas Kirchhoff, Zsofia Stadler, Mark Robson, Joseph Vijai, Kenneth Offit, Agata Smogorzewska

PLoS One. 2013; 8(6): e66961. Published online 2013 Jun 26. doi: 10.1371/journal.pone.0066961

PMCID:: PMC3694110

Article PDF–1010K

Select item 33153976.

Analysis of SLX4/FANCP in non-BRCA1/2-mutated breast cancer families

Juana Fernández-Rodríguez, Francisco Quiles, Ignacio Blanco, Alex Teulé, Lídia Feliubadaló, Jesús del Valle, Mónica Salinas, Àngel Izquierdo, Esther Darder, Detlev Schindler, Gabriel Capellá, Joan Brunet, Conxi Lázaro, Miguel Angel Pujana

BMC Cancer. 2012; 12: 84. Published online 2012 Mar 8. doi: 10.1186/1471-2407-12-84

PMCID:: PMC3315397

Article PDF–272K

Select item 32856207.

Sequencing Analysis of SLX4/FANCP Gene in Italian Familial Breast Cancer Cases

Irene Catucci, Mara Colombo, Paolo Verderio, Loris Bernard, Filomena Ficarazzi, Frederique Mariette, Monica Barile, Bernard Peissel, Elisa Cattaneo, Siranoush Manoukian, Paolo Radice, Paolo Peterlongo

PLoS One. 2012; 7(2): e31038. Published online 2012 Feb 23. doi: 10.1371/journal.pone.0031038

PMCID:: PMC3285620

Article PDF–66K

Select item 77546858.

SLX4–XPF mediates DNA damage responses to replication stress induced by DNA–protein interactions

Riko Ishimoto, Yota Tsuzuki, Tomoki Matsumura, Seiichiro Kurashige, Kouki Enokitani, Koki Narimatsu, Mitsunori Higa, Nozomi Sugimoto, Kazumasa Yoshida, Masatoshi Fujita

J Cell Biol. 2021 Jan 4; 220(1): e202003148. Published online 2020 Dec 21. doi: 10.1083/jcb.202003148

PMCID:: PMC7754685

Article PDF–4.4M

Select item 76106489.

Coordinated roles of SLX4 and MutSβ in DNA repair and the maintenance of genome stability

Sarah J. Young, Stephen C. West

Crit Rev Biochem Mol Biol. Author manuscript; available in PMC 2021 Apr 20.

Published in final edited form as: Crit Rev Biochem Mol Biol. 2021 Apr 1; 56(2): 157–177. Published online 2021 Feb 17. doi: 10.1080/10409238.2021.1881433

PMCID:: PMC7610648

Article PDF–3.2M

Select item 636280910.

RAD52 and SLX4 act nonepistatically to ensure telomere stability during alternative telomere lengthening

Priyanka Verma, Robert L. Dilley, Tianpeng Zhang, Melina T. Gyparaki, Yiwen Li, Roger A. Greenberg

Genes Dev. 2019 Feb 1; 33(3-4): 221–235. doi: 10.1101/gad.319723.118

PMCID:: PMC6362809

Article PDF–7.4M

Select item 562387311.

BLM and SLX4 play opposing roles in recombination‐dependent replication at human telomeres

Alexander P Sobinoff, Joshua AM Allen, Axel A Neumann, Sile F Yang, Monica E Walsh, Jeremy D Henson, Roger R Reddel, Hilda A Pickett

EMBO J. 2017 Oct 2; 36(19): 2907–2919. Published online 2017 Sep 6. doi: 10.15252/embj.201796889

PMCID:: PMC5623873

Article PDF–1.4M

Select item 483360012.

Paternal or maternal uniparental disomy of chromosome 16 resulting in homozygosity of a mutant allele causes Fanconi anemia

Frank X. Donovan, Danielle C. Kimble, Yonghwan Kim, Francis P. Lach, Ursula Harper, Aparna Kamat, MaryPat Jones, Erica M. Sanborn, Rebecca Tryon, John E. Wagner, Margaret L. MacMillan, Elaine A. Ostrander, Arleen D. Auerbach, Agata Smogorzewska, Settara C. Chandrasekharappa

Hum Mutat. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Hum Mutat. 2016 May; 37(5): 465–468. Published online 2016 Feb 23. doi: 10.1002/humu.22962

PMCID:: PMC4833600

Article PDF–642K

Select item 828552613.

Abraxas suppresses DNA end resection and limits break-induced replication by controlling SLX4/MUS81 chromatin loading in response to TOP1 inhibitor-induced DNA damage

Xiao Wu, Bin Wang

Nat Commun. 2021; 12: 4373. Published online 2021 Jul 16. doi: 10.1038/s41467-021-24665-w

PMCID:: PMC8285526

Article PDF–3.6M

Select item 534955014.

SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells

Eva Malacaria, Annapaola Franchitto, Pietro Pichierri

Sci Rep. 2017; 7: 44464. Published online 2017 Mar 14. doi: 10.1038/srep44464

PMCID:: PMC5349550

Article PDF–1.8M

Select item 465176015.

Physical interaction between SLX4 (FANCP) and XPF (FANCQ) proteins and biological consequences of interaction-defective missense mutations

Keiji Hashimoto, Kunio Wada, Kyomu Matsumoto, Masaaki Moriya

DNA Repair (Amst) Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: DNA Repair (Amst). 2015 Nov; 35: 48–54. Published online 2015 Sep 30. doi: 10.1016/j.dnarep.2015.09.022

PMCID:: PMC4651760

Article PDF–1.1M

Select item 407535516.

Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia

Christophe Lachaud, Dennis Castor, Karolina Hain, Ivan Muñoz, Jamie Wilson, Thomas J. MacArtney, Detlev Schindler, John Rouse

J Cell Sci. 2014 Jul 1; 127(13): 2811–2817. doi: 10.1242/jcs.146167

PMCID:: PMC4075355

Article

Select item 600750917.

Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress

Anita Palma, Giusj Monia Pugliese, Ivana Murfuni, Veronica Marabitti, Eva Malacaria, Sara Rinalducci, Anna Minoprio, Massimo Sanchez, Filomena Mazzei, Lello Zolla, Annapaola Franchitto, Pietro Pichierri

Nucleic Acids Res. 2018 Jun 1; 46(10): 5109–5124. Published online 2018 Apr 18. doi: 10.1093/nar/gky280

PMCID:: PMC6007509

Article PDF–3.6M

Select item 502180618.

Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 Recruitment

Oliver I. Fregoso, Michael Emerman

mBio. 2016 Sep-Oct; 7(5): e01433-16. Published online 2016 Sep 13. doi: 10.1128/mBio.01433-16

PMCID:: PMC5021806

Article PDF–2.1M

Select item 425197919.

Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein

Nidhi Nair, Dennis Castor, Thomas Macartney, John Rouse

DNA Repair (Amst) 2014 Dec; 24: 131–137. doi: 10.1016/j.dnarep.2014.08.004

PMCID:: PMC4251979

Article PDF–2.2M

Select item 384429020.

Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions

Elizabeth Garner, Yonghwan Kim, Francis P. Lach, Molly C. Kottemann, Agata Smogorzewska

Cell Rep. Author manuscript; available in PMC 2014 Oct 17.

Published in final edited form as: Cell Rep. 2013 Oct 17; 5(1): 10.1016/j.celrep.2013.08.041. Published online 2013 Sep 27. doi: 10.1016/j.celrep.2013.08.041

PMCID:: PMC3844290

Article PDF–2.9M

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