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Items: 1 to 20 of 57

1.
Polycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity
Chao-Shun Yang, Kung-Yen Chang, Jason Dang, Tariq M. Rana
Sci Rep. 2016; 6: 26899. Published online 2016 Jun 1. doi: 10.1038/srep26899
PMCID:
PMC4888081
ArticlePDF–2.1M
2.
mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity.
M Kanno, M Hasegawa, A Ishida, K Isono, M Taniguchi
EMBO J. 1995 Nov 15; 14(22): 5672–5678. doi: 10.1002/j.1460-2075.1995.tb00254.x
PMCID:
PMC394682
SummaryPage BrowsePDF–1.6M
3.
MEL-18 Interacts with HSF2 and the SUMO E2 UBC9 to Inhibit HSF2 Sumoylation
Jie Zhang, Michael L. Goodson, Yiling Hong, Kevin D. Sarge
J Biol Chem. 2008 Mar 21; 283(12): 7464–7469. doi: 10.1074/jbc.M707122200
PMCID:
PMC2274900
ArticlePDF–962K
4.
The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex
Jeffrey M. Trimarchi, Brian Fairchild, Jessica Wen, Jacqueline A. Lees
Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4): 1519–1524. Published online 2001 Jan 30. doi: 10.1073/pnas.041597698
PMCID:
PMC29289
ArticlePDF–264K
5.
Functional redundancy among Polycomb complexes in maintaining the pluripotent state of embryonic stem cells
Yaru Zhu, Lixia Dong, Congcong Wang, Kunying Hao, Jingnan Wang, Linchun Zhao, Lijun Xu, Yin Xia, Qing Jiang, Jinzhong Qin
Stem Cell Reports. 2022 May 10; 17(5): 1198–1214. Published online 2022 Mar 31. doi: 10.1016/j.stemcr.2022.02.020
PMCID:
PMC9120860
ArticlePDF–8.6M
6.
L3MBTL2 protein acts in concert with PcG protein mediated monoubiquitination of H2A to establish a repressive chromatin structure
Patrick Trojer, Alina R. Cao, Zhonghua Gao, Yan Li, Jin Zhang, Xiaoqin Xu, Guohong Li, Regine Losson, Hediye Erdjument-Bromage, Paul Tempst, Peggy J. Farnham, Danny Reinberg
Mol Cell. Author manuscript; available in PMC 2011 Nov 20.
Published in final edited form as: Mol Cell. 2011 May 20; 42(4): 438–450. doi: 10.1016/j.molcel.2011.04.004
PMCID:
PMC3142354
ArticlePDF–1.4M
7.
PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression
Xianchun Lan, Song Ding, Tianzhe Zhang, Ying Yi, Conghui Li, Wenwen Jin, Jian Chen, Kaiwei Liang, Hengbin Wang, Wei Jiang
Nat Commun. 2022; 13: 4601. Published online 2022 Aug 6. doi: 10.1038/s41467-022-32295-z
PMCID:
PMC9357003
ArticlePDF–3.7M
8.
The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex
Lucie Kozakova, Lucie Vondrova, Karel Stejskal, Panagoula Charalabous, Peter Kolesar, Alan R Lehmann, Stjepan Uldrijan, Christopher M Sanderson, Zbynek Zdrahal, Jan J Palecek
Cell Cycle. 2015 Mar 15; 14(6): 920–930. Published online 2015 Jan 15. doi: 10.1080/15384101.2014.1000112
PMCID:
PMC4614679
ArticlePDF–558K
9.
Several Distinct Polycomb Complexes Regulate and Co-Localize on the INK4a Tumor Suppressor Locus
Goedele N. Maertens, Selma El Messaoudi-Aubert, Tomas Racek, Julie K. Stock, James Nicholls, Marc Rodriguez-Niedenführ, Jesus Gil, Gordon Peters
PLoS One. 2009; 4(7): e6380. Published online 2009 Jul 28. doi: 10.1371/journal.pone.0006380
PMCID:
PMC2713427
ArticlePDF–582K
10.
A Myc rather than core pluripotency module accounts for the shared signatures of embryonic stem and cancer cells
Jonghwan Kim, Andrew J. Woo, Jianlin Chu, Jonathan W. Snow, Yuko Fujiwara, Chul Geun Kim, Alan B. Cantor, Stuart H. Orkin
Cell. Author manuscript; available in PMC 2011 Apr 15.
Published in final edited form as: Cell. 2010 Oct 15; 143(2): 313–324. doi: 10.1016/j.cell.2010.09.010
PMCID:
PMC3018841
ArticlePDF–5.8M
11.
AUTS2 confers gene activation to Polycomb group proteins in the CNS
Zhonghua Gao, Pedro Lee, James M. Stafford, Melanie von Schimmelmann, Anne Schaefer, Danny Reinberg
Nature. Author manuscript; available in PMC 2015 Jun 18.
Published in final edited form as: Nature. 2014 Dec 18; 516(7531): 349–354. doi: 10.1038/nature13921
PMCID:
PMC4323097
ArticlePDF–4.2M
12.
PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes
Zhonghua Gao, Jin Zhang, Roberto Bonasio, Francesco Strino, Ayana Sawai, Fabio Parisi, Yuval Kluger, Danny Reinberg
Mol Cell. Author manuscript; available in PMC 2013 Feb 10.
Published in final edited form as: Mol Cell. 2012 Feb 10; 45(3): 344–356. doi: 10.1016/j.molcel.2012.01.002
PMCID:
PMC3293217
ArticlePDF–2.8M
13.
Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis
Jingwei Cheng, Donglim Esther Park, Christian Berrios, Elizabeth A. White, Reety Arora, Rosa Yoon, Timothy Branigan, Tengfei Xiao, Thomas Westerling, Alexander Federation, Rhamy Zeid, Benjamin Strober, Selene K. Swanson, Laurence Florens, James E. Bradner, Myles Brown, Peter M. Howley, Megha Padi, Michael P. Washburn, James A. DeCaprio
PLoS Pathog. 2017 Oct; 13(10): e1006668. Published online 2017 Oct 13. doi: 10.1371/journal.ppat.1006668
PMCID:
PMC5640240
ArticlePDF–9.9M
14.
Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15
Sebastian D. Hayes, Han Liu, Ewan MacDonald, Christopher M. Sanderson, Judy M. Coulson, Michael J. Clague, Sylvie Urbé
J Biol Chem. 2012 Dec 14; 287(51): 43007–43018. Published online 2012 Oct 26. doi: 10.1074/jbc.M112.386938
PMCID:
PMC3522295
ArticlePDF–2.6M
15.
USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c
Ye Yao, Weijie Ma, Yonghua Guo, Yingyi Liu, Peng Xia, Xiaoling Wu, Yiran Chen, Kunlei Wang, Chengjie Mei, Ganggang Wang, Xiaomian Li, Zhonglin Zhang, Xi Chen, Yufeng Yuan
Oncogenesis. 2022 Dec; 11(1): 31. Published online 2022 Jun 2. doi: 10.1038/s41389-022-00404-8
Correction in:
Oncogenesis. 2023 Dec; 12(1): 27.
PMCID:
PMC9163188
ArticlePDF–8.2M
16.
Genome-wide Association Analysis Identifies 14 New Risk Loci for Schizophrenia
Stephan Ripke, Colm O'Dushlaine, Kimberly Chambert, Jennifer L Moran, Anna K Kähler, Susanne Akterin, Sarah Bergen, Ann L Collins, James J Crowley, Menachem Fromer, Yunjung Kim, Sang Hong Lee, Patrik KE Magnusson, Nick Sanchez, Eli A Stahl, Stephanie Williams, Naomi R Wray, Kai Xia, Francesco Bettella, Anders D Børglum, Brendan K Bulik-Sullivan, Paul Cormican, Nick Craddock, Christiaan de Leeuw, Naser Durmishi, Michael Gill, Vera Golimbet, Marian L Hamshere, Peter Holmans, David M Hougaard, Kenneth S Kendler, Kuang Lin, Derek W Morris, Ole Mors, Preben B Mortensen, Benjamin M Neale, Francis A O'Neill, Michael J Owen, MilicaPejovic Milovancevic, Danielle Posthuma, John Powell, Alexander L Richards, Brien P Riley, Douglas Ruderfer, Dan Rujescu, Engilbert Sigurdsson, Teimuraz Silagadze, August B Smit, Hreinn Stefansson, Stacy Steinberg, Jaana Suvisaari, Sarah Tosato, Matthijs Verhage, James T Walters, Multicenter Genetic Studies of Schizophrenia Consortium, Psychosis Endophenotypes Consortium, Wellcome Trust Case-Control Consortium, Elvira Bramon, Aiden P Corvin, Michael C O'Donovan, Kari Stefansson, Edward Scolnick, Shaun Purcell, Steve McCarroll, Pamela Sklar, Christina M Hultman, Patrick F Sullivan
Nat Genet. Author manuscript; available in PMC 2014 Apr 1.
Published in final edited form as: Nat Genet. 2013 Oct; 45(10): 1150–1159. Published online 2013 Aug 25. doi: 10.1038/ng.2742
PMCID:
PMC3827979
ArticlePDF–848K
17.
Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks
Jonathan Woodsmith, Robert C. Jenn, Chris M. Sanderson
Mol Cell Proteomics. 2012 Jul; 11(7): M111.016162. Published online 2012 Apr 5. doi: 10.1074/mcp.M111.016162
PMCID:
PMC3394952
ArticlePDF–3.3M
18.
Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations
Dervla M. Connaughton, Rufeng Dai, Danielle J. Owen, Jonathan Marquez, Nina Mann, Adda L. Graham-Paquin, Makiko Nakayama, Etienne Coyaud, Estelle M.N. Laurent, Jonathan R. St-Germain, Lot Snijders Blok, Arianna Vino, Verena Klämbt, Konstantin Deutsch, Chen-Han Wilfred Wu, Caroline M. Kolvenbach, Franziska Kause, Isabel Ottlewski, Ronen Schneider, Thomas M. Kitzler, Amar J. Majmundar, Florian Buerger, Ana C. Onuchic-Whitford, Mao Youying, Amy Kolb, Daanya Salmanullah, Evan Chen, Amelie T. van der Ven, Jia Rao, Hadas Ityel, Steve Seltzsam, Johanna M. Rieke, Jing Chen, Asaf Vivante, Daw-Yang Hwang, Stefan Kohl, Gabriel C. Dworschak, Tobias Hermle, Mariëlle Alders, Tobias Bartolomaeus, Stuart B. Bauer, Michelle A. Baum, Eva H. Brilstra, Thomas D. Challman, Jacob Zyskind, Carrie E. Costin, Katrina M. Dipple, Floor A. Duijkers, Marcia Ferguson, David R. Fitzpatrick, Roger Fick, Ian A. Glass, Peter J. Hulick, Antonie D. Kline, Ilona Krey, Selvin Kumar, Weining Lu, Elysa J. Marco, Ingrid M. Wentzensen, Heather C. Mefford, Konrad Platzer, Inna S. Povolotskaya, Juliann M. Savatt, Natalia V. Shcherbakova, Prabha Senguttuvan, Audrey E. Squire, Deborah R. Stein, Isabelle Thiffault, Victoria Y. Voinova, Michael J.G. Somers, Michael A. Ferguson, Avram Z. Traum, Ghaleb H. Daouk, Ankana Daga, Nancy M. Rodig, Paulien A. Terhal, Ellen van Binsbergen, Loai A. Eid, Velibor Tasic, Hila Milo Rasouly, Tze Y. Lim, Dina F. Ahram, Ali G. Gharavi, Heiko M. Reutter, Heidi L. Rehm, Daniel G. MacArthur, Monkol Lek, Kristen M. Laricchia, Richard P. Lifton, Hong Xu, Shrikant M. Mane, Simone Sanna-Cherchi, Andrew D. Sharrocks, Brian Raught, Simon E. Fisher, Maxime Bouchard, Mustafa K. Khokha, Shirlee Shril, Friedhelm Hildebrandt
Am J Hum Genet. 2020 Oct 1; 107(4): 727–742. Published online 2020 Sep 4. doi: 10.1016/j.ajhg.2020.08.013
PMCID:
PMC7536580
ArticlePDF–2.3M
19.
Interaction Proteomics Analysis of Polycomb Proteins Defines Distinct PRC1 Complexes in Mammalian Cells
Julien Vandamme, Pamela Völkel, Claire Rosnoblet, Perrine Le Faou, Pierre-Olivier Angrand
Mol Cell Proteomics. 2011 Apr; 10(4): M110.002642. Published online 2011 Jan 31. doi: 10.1074/mcp.M110.002642
PMCID:
PMC3069339
ArticlePDF–2.4M
20.
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
Gabriel Markson, Christina Kiel, Russell Hyde, Stephanie Brown, Panagoula Charalabous, Anja Bremm, Jennifer Semple, Jonathan Woodsmith, Simon Duley, Kourosh Salehi-Ashtiani, Marc Vidal, David Komander, Luis Serrano, Paul Lehner, Christopher M. Sanderson
Genome Res. 2009 Oct; 19(10): 1905–1911. doi: 10.1101/gr.093963.109
PMCID:
PMC2765280
ArticlePDF–425K

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