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Select item 39106281.

RIG-I–like receptor LGP2 protects tumor cells from ionizing radiation

Ryan C. Widau, Akash D. Parekh, Mark C. Ranck, Daniel W. Golden, Kiran A. Kumar, Ravi F. Sood, Sean P. Pitroda, Zhengkai Liao, Xiaona Huang, Thomas E. Darga, David Xu, Lei Huang, Jorge Andrade, Bernard Roizman, Ralph R. Weichselbaum, Nikolai N. Khodarev

Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4): E484–E491. Published online 2014 Jan 13. doi: 10.1073/pnas.1323253111

PMCID:: PMC3910628

Article PDF–1.3M

Select item 30774162.

Impaired Cellular Responses to Cytosolic DNA or Infection with Listeria monocytogenes and Vaccinia Virus in the Absence of the Murine LGP2 Protein

Darja Pollpeter, Akihiko Komuro, Glen N. Barber, Curt M. Horvath

PLoS One. 2011; 6(4): e18842. Published online 2011 Apr 14. doi: 10.1371/journal.pone.0018842

PMCID:: PMC3077416

Article PDF–605K

Select item 110174953.

Interferon-α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis

Kai-Wei Jia, Ren-Qi Yao, Yi-Wen Fan, Ding-Ji Zhang, Ye Zhou, Min-Jun Wang, Li-Yuan Zhang, Yue Dong, Zhi-Xuan Li, Su-Yuan Wang, Mu Wang, Yun-Hui Li, Lu-Xin Zhang, Ting Lei, Liang-Chen Gui, Shan Lu, Ying-Yun Yang, Si-Xian Wang, Yi-Zhi Yu, Yong-Ming Yao, Jin Hou

Mil Med Res. 2024; 11: 22. Published online 2024 Apr 15. doi: 10.1186/s40779-024-00524-9

PMCID:: PMC11017495

Article PDF–9.4M

Select item 34573294.

LGP2 Downregulates Interferon Production during Infection with Seasonal Human Influenza A Viruses That Activate Interferon Regulatory Factor 3

Meghana Malur, Michael Gale, Jr, Robert M. Krug

J Virol. 2012 Oct; 86(19): 10733–10738. doi: 10.1128/JVI.00510-12

PMCID:: PMC3457329

Article PDF–749K

Select item 66923875.

RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection

Amy E. L. Stone, Richard Green, Courtney Wilkins, Emily A. Hemann, Michael Gale, Jr.

Nat Commun. 2019; 10: 3649. Published online 2019 Aug 13. doi: 10.1038/s41467-019-11250-5

PMCID:: PMC6692387

Article PDF–3.9M

Select item 39104446.

THE RIG-I LIKE RECEPTOR LGP2 CONTROLS CD8⁺ T CELL SURVIVAL AND FITNESS

Mehul S. Suthar, Hilario J. Ramos, Margaret M. Brassil, Jason Netland, Craig P. Chappell, Gabriele Blahnik, Aimee McMillan, Michael S. Diamond, Edward A. Clark, Michael J. Bevan, Michael Gale, Jr.

Immunity. Author manuscript; available in PMC 2014 Feb 3.

Published in final edited form as: Immunity. 2012 Aug 24; 37(2): 235–248. Published online 2012 Jul 26. doi: 10.1016/j.immuni.2012.07.004

PMCID:: PMC3910444

Article PDF–3.5M

Select item 39678617.

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

Safia Deddouche, Delphine Goubau, Jan Rehwinkel, Probir Chakravarty, Sharmin Begum, Pierre V Maillard, Annabel Borg, Nik Matthews, Qian Feng, Frank J M van Kuppeveld, Caetano Reis e Sousa

eLife. 2014; 3: e01535. Published online 2014 Feb 18. doi: 10.7554/eLife.01535

PMCID:: PMC3967861

Article PDF–2.2M

Select item 31265148.

Ambivalent Role of the Innate Immune Response in Rabies Virus Pathogenesis

Damien Chopy, Julien Pothlichet, Mireille Lafage, Françoise Mégret, Laurence Fiette, Mustapha Si-Tahar, Monique Lafon

J Virol. 2011 Jul; 85(13): 6657–6668. doi: 10.1128/JVI.00302-11

PMCID:: PMC3126514

Article PDF–3.5M

Select item 28244079.

LGP2 is a positive regulator of RIG-I– and MDA5-mediated antiviral responses

Takashi Satoh, Hiroki Kato, Yutaro Kumagai, Mitsutoshi Yoneyama, Shintaro Sato, Kazufumi Matsushita, Tohru Tsujimura, Takashi Fujita, Shizuo Akira, Osamu Takeuchi

Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4): 1512–1517. Published online 2010 Jan 8. doi: 10.1073/pnas.0912986107

PMCID:: PMC2824407

Article PDF–790K

Select item 167630210.

RNA- and Virus-Independent Inhibition of Antiviral Signaling by RNA Helicase LGP2

Akihiko Komuro, Curt M. Horvath

J Virol. 2006 Dec; 80(24): 12332–12342. Published online 2006 Oct 4. doi: 10.1128/JVI.01325-06

PMCID:: PMC1676302

Article PDF–1.0M

Select item 682087111.

RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination

Kendra M. Quicke, Kristin Y. Kim, Curt M. Horvath, Mehul S. Suthar

J Interferon Cytokine Res. 2019 Nov 1; 39(11): 669–683. Published online 2019 Oct 29. doi: 10.1089/jir.2019.0059

PMCID:: PMC6820871

Article PDF–1.2M

Select item 598975712.

RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling

Jean‐Patrick Parisien, Jessica J Lenoir, Roli Mandhana, Kenny R Rodriguez, Kenin Qian, Annie M Bruns, Curt M Horvath

EMBO Rep. 2018 Jun; 19(6): e45176. Published online 2018 Apr 16. doi: 10.15252/embr.201745176

PMCID:: PMC5989757

Article PDF–2.2M

Select item 844633513.

Protein Kinase R and the Integrated Stress Response drive immunopathology caused by mutations in the RNA deaminase ADAR1

Megan Maurano, Jessica M. Snyder, Caitlin Connelly, Jorge Henao-Mejia, Carmela Sidrauski, Daniel B. Stetson

Immunity. Author manuscript; available in PMC 2022 Sep 14.

Published in final edited form as: Immunity. 2021 Sep 14; 54(9): 1948–1960.e5. Published online 2021 Aug 2. doi: 10.1016/j.immuni.2021.07.001

PMCID:: PMC8446335

Article PDF–3.6M

Select item 385885314.

Completion of the entire hepatitis C virus life-cycle in genetically humanized mice

Marcus Dorner, Joshua A. Horwitz, Bridget M. Donovan, Rachael N. Labitt, William C. Budell, Tamar Friling, Alexander Vogt, Maria Teresa Catanese, Takashi Satoh, Taro Kawai, Shizuo Akira, Mansun Law, Charles M. Rice, Alexander Ploss

Nature. Author manuscript; available in PMC 2014 Mar 13.

Published in final edited form as: Nature. 2013 Sep 12; 501(7466): 237–241. Published online 2013 Jul 31. doi: 10.1038/nature12427

PMCID:: PMC3858853

Article PDF–1.1M

Select item 316572415.

DDX60, a DEXD/H Box Helicase, Is a Novel Antiviral Factor Promoting RIG-I-Like Receptor-Mediated Signaling

Moeko Miyashita, Hiroyuki Oshiumi, Misako Matsumoto, Tsukasa Seya

Mol Cell Biol. 2011 Sep; 31(18): 3802–3819. doi: 10.1128/MCB.01368-10

PMCID:: PMC3165724

Article PDF–6.3M

Select item 365256016.

DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells

Zhiqiang Zhang, Taeil Kim, Musheng Bao, Valeria Facchinetti, Sung Yun Jung, Amir Ali Ghaffari, Jun Qin, Genhong Cheng, Yong-Jun Liu

Immunity. Author manuscript; available in PMC 2013 May 13.

Published in final edited form as: Immunity. 2011 Jun 24; 34(6): 866–878. doi: 10.1016/j.immuni.2011.03.027

PMCID:: PMC3652560

Article PDF–4.6M

Select item 347860617.

Impact of lactobacilli on orally acquired listeriosis

Cristel Archambaud, Marie-Anne Nahori, Guillaume Soubigou, Christophe Bécavin, Laure Laval, Pierre Lechat, Tamara Smokvina, Philippe Langella, Marc Lecuit, Pascale Cossart

Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41): 16684–16689. Published online 2012 Sep 24. doi: 10.1073/pnas.1212809109

PMCID:: PMC3478606

Article PDF–772K

Select item 626277718.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Article

Select item 141356819.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 1091766020.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

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