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Select item 80458981.

Variant recurrence confirms the existence of a FBXO31‐related spastic‐dystonic cerebral palsy syndrome

Ivana Dzinovic, Matej Škorvánek, Petra Pavelekova, Chen Zhao, Boris Keren, Sandra Whalen, Somayeh Bakhtiari, Sheng Chih Jin, Michael C. Kruer, Robert Jech, Juliane Winkelmann, Michael Zech

Ann Clin Transl Neurol. 2021 Apr; 8(4): 951–955. Published online 2021 Mar 6. doi: 10.1002/acn3.51335

PMCID:: PMC8045898

Article PDF–248K

Select item 67913332.

The tumor suppressor FBXO31 preserves genomic integrity by regulating DNA replication and segregation through precise control of cyclin A levels

Parul Dutta, Sehbanul Islam, Srinadh Choppara, Pallabi Sengupta, Anil Kumar, Avinash Kumar, Mohan R. Wani, Subhrangsu Chatterjee, Manas Kumar Santra

J Biol Chem. 2019 Oct 11; 294(41): 14879–14895. Published online 2019 Aug 14. doi: 10.1074/jbc.RA118.007055

PMCID:: PMC6791333

Article PDF–3.9M

Select item 109175493.

Aberrantly High FBXO31 Impairs Oocyte Quality in Premature Ovarian Insufficiency

Feiyan Zhao, Long Yan, Xuehan Zhao, Jiaqi Wu, Ying Fang, Zhimin Xin, Hongmei Wang, Xiaokui Yang

Aging Dis. 2024 Apr 1; 15(2): 804–823. Published online 2024 Apr 1. doi: 10.14336/AD.2023.0809

PMCID:: PMC10917549

Article PDF–4.9M

Select item 99385684.

LincRNA ZNF529-AS1 inhibits hepatocellular carcinoma via FBXO31 and predicts the prognosis of hepatocellular carcinoma patients

Yang Ma, Wan-liang Sun, Shuo Shuo Ma, Guanru Zhao, Zhong Liu, Zheng Lu, Dengyong Zhang

BMC Bioinformatics. 2023; 24: 54. Published online 2023 Feb 17. doi: 10.1186/s12859-023-05189-0

PMCID:: PMC9938568

Article PDF–2.3M

Select item 88421635.

Novel variants underlying autosomal recessive neurodevelopmental disorders with intellectual disability in Iranian consanguineous families

Mahdiyeh Moudi, Mohammad Yahya Vahidi Mehrjardi, Hossein Hozhabri, Zahra Metanat, Seyed Mehdi Kalantar, Mohsen Taheri, Nasrin Ghasemi, Mohammadreza Dehghani

J Clin Lab Anal. 2022 Feb; 36(2): e24241. Published online 2022 Jan 12. doi: 10.1002/jcla.24241

PMCID:: PMC8842163

Article PDF–1.0M

Select item 85772246.

Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis

Shanshan Duan, Loredana Moro, Rui Qu, Daniele Simoneschi, Hyunwoo Cho, Shaowen Jiang, Huiyong Zhao, Qing Chang, Elisa de Stanchina, Arnaldo A. Arbini, Michele Pagano

Cell Rep. Author manuscript; available in PMC 2021 Nov 9.

Published in final edited form as: Cell Rep. 2021 Oct 19; 37(3): 109870. doi: 10.1016/j.celrep.2021.109870

PMCID:: PMC8577224

Article PDF–1.3M

Select item 79527967.

MicroRNA‐210 targets FBXO31 to inhibit tumor progression and regulates the Wnt/β‐catenin signaling pathway and EMT in esophageal squamous cell carcinoma

Jing Meng, Chao Zhang, Tongquan Zhao, Guangwen Shi, Jingjing Zhao, Zhaoxia Lin

Thorac Cancer. 2021 Mar; 12(6): 932–940. Published online 2021 Feb 3. doi: 10.1111/1759-7714.13860

PMCID:: PMC7952796

Article PDF–5.0M

Select item 107869078.

FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation

Kai Chen, Yue Wang, Xingna Dai, Jingjing Luo, Shangshang Hu, Zhihui Zhou, Jinglong Shi, Xueshan Pan, Tong Cao, Jun Xia, Yuyun Li, Zhiwei Wang, Jia Ma

Cell Death Dis. 2024 Jan; 15(1): 37. Published online 2024 Jan 12. doi: 10.1038/s41419-024-06425-y

PMCID:: PMC10786907

Article PDF–5.1M

Select item 41716219.

F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a

Xinchao Zhang, Ye Kong, Xia Xu, Huaixin Xing, Yingjie Zhang, Fengjuan Han, Wenjuan Li, Qing Yang, Jiping Zeng, Jihui Jia, Zhifang Liu

Oncotarget. 2014 Aug; 5(15): 6178–6190. Published online 2014 Jul 8. doi: 10.18632/oncotarget.2183

PMCID:: PMC4171621

Article PDF–2.2M

Select item 411811210.

F-Box Only Protein 31 (FBXO31) Negatively Regulates p38 Mitogen-activated Protein Kinase (MAPK) Signaling by Mediating Lysine 48-linked Ubiquitination and Degradation of Mitogen-activated Protein Kinase Kinase 6 (MKK6)

Jia Liu, Liang Han, Bin Li, Jie Yang, Michael S. Y. Huen, Xin Pan, Sai Wah Tsao, Annie L. M. Cheung

J Biol Chem. 2014 Aug 1; 289(31): 21508–21518. Published online 2014 Jun 16. doi: 10.1074/jbc.M114.560342

PMCID:: PMC4118112

Article PDF–2.3M

Select item 358633911.

The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, Herceptin sensitivity and tumorigenesis

Chia-Hsin Chan, Chien-Feng Li, Wei-Lei Yang, Yuan Gao, Szu-Wei Lee, Zizhen Feng, Hsuan-Ying Huang, Kelvin K. C. Tsai, Leo G. Flores, Yiping Shao, John D. Hazle, Dihua Yu, Wenyi Wei, Dos Sarbassov, Mien-Chie Hung, Keiichi I. Nakayama, Hui-Kuan Lin

Cell. Author manuscript; available in PMC 2013 May 25.

Published in final edited form as: Cell. 2012 May 25; 149(5): 1098–1111. doi: 10.1016/j.cell.2012.02.065

PMCID:: PMC3586339

Article PDF–3.1M

Select item 793327512.

Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

Dawoon Baek, Kwang Hwan Park, Kyoung-Mi Lee, Sujin Jung, Soyeong Joung, Jihyun Kim, Jin Woo Lee

Cell Death Dis. 2021 Mar; 12(3): 238. Published online 2021 Mar 4. doi: 10.1038/s41419-021-03517-x

PMCID:: PMC7933275

Article PDF–2.1M

Select item 632887413.

Prognostic values of F-box members in breast cancer: an online database analysis and literature review

Xiaochen Wang, Tao Zhang, Shizhen Zhang, Jinlan Shan

Biosci Rep. 2019 Jan 31; 39(1): BSR20180949. Prepublished online 2018 Oct 19. Published online 2019 Jan 3. doi: 10.1042/BSR20180949

PMCID:: PMC6328874

Article PDF–819K

Select item 542924414.

A MicroRNA/Ubiquitin Ligase Feedback Loop Regulates Slug-Mediated Invasion in Breast Cancer

Rajesh Kumar Manne, Yashika Agrawal, Anil Bargale, Asha Patel, Debasish Paul, Neha Anilkumar Gupta, Srikanth Rapole, Vasudevan Seshadri, Deepa Subramanyam, Praveenkumar Shetty, Manas Kumar Santra

Neoplasia. 2017 Jun; 19(6): 483–495. Published online 2017 May 10. doi: 10.1016/j.neo.2017.02.013

PMCID:: PMC5429244

Article PDF–1.5M

Select item 850719715.

FBXL20 promotes breast cancer malignancy by inhibiting apoptosis through degradation of PUMA and BAX

Rajesh Kumar Manne, Yashika Agrawal, Sunil K. Malonia, Shahid Banday, Sarathkumar Edachery, Asha Patel, Avinash Kumar, Praveenkumar Shetty, Manas Kumar Santra

J Biol Chem. 2021 Oct; 297(4): 101253. Published online 2021 Sep 26. doi: 10.1016/j.jbc.2021.101253