PMC Links for Gene (Select 74126) - PMC

Juncheng Wei, Yanzhi Yuan, Lu Chen, Yuanming Xu, Yuehui Zhang, Yajun Wang, Yanjie Yang, Clara Bien Peek, Lauren Diebold, Yi Yang, Beixue Gao, Chaozhi Jin, Johanna Melo-Cardenas, Navdeep S. Chandel, Donna D. Zhang, Hui Pan, Kezhong Zhang, Jian Wang, Fuchu He, Deyu Fang

Nat Commun. 2018; 9: 3659. Published online 2018 Sep 10. doi: 10.1038/s41467-018-06091-7

PMCID:: PMC6131148

Article PDF–3.8M

Select item 46702624.

Hrd1 and ER-Associated Protein Degradation, ERAD, Are Critical Elements of the Adaptive ER Stress Response in Cardiac Myocytes

Shirin Doroudgar, Mirko Völkers, Donna J Thuerauf, Mohsin Khan, Sadia Mohsin, Jonathan L Respress, Wei Wang, Natalie Gude, Oliver J Müller, Xander HT Wehrens, Mark A Sussman, Christopher C Glembotski

Circ Res. Author manuscript; available in PMC 2016 Aug 28.

Published in final edited form as: Circ Res. 2015 Aug 28; 117(6): 536–546. Published online 2015 Jul 2. doi: 10.1161/CIRCRESAHA.115.306993

PMCID:: PMC4670262

Article PDF–1.4M

Select item 46425545.

Experimental study of the protective effects of SYVN1 against diabetic retinopathy

Shuo Yang, Heng He, Qi Si Ma, Yong Zhang, Ying Zhu, Xing Wan, Feng Wen Wang, Shuai Shuai Wang, Lei Liu, Bin Li

Sci Rep. 2015; 5: 14036. Published online 2015 Sep 11. doi: 10.1038/srep14036

PMCID:: PMC4642554

Article PDF–1.5M

Select item 40067996.

Effects of Oxidative Stress on the Solubility of HRD1, a Ubiquitin Ligase Implicated in Alzheimer’s Disease

Ryo Saito, Masayuki Kaneko, Yoshihisa Kitamura, Kazuyuki Takata, Koichi Kawada, Yasunobu Okuma, Yasuyuki Nomura

PLoS One. 2014; 9(5): e94576. Published online 2014 May 1. doi: 10.1371/journal.pone.0094576

PMCID:: PMC4006799

Article PDF–4.8M

Select item 29635977.

E3 Ubiquitin Ligase Synoviolin Is Involved in Liver Fibrogenesis

Daisuke Hasegawa, Ryoji Fujii, Naoko Yagishita, Nobuyuki Matsumoto, Satoko Aratani, Toshihiko Izumi, Kazuko Azakami, Minako Nakazawa, Hidetoshi Fujita, Tomoo Sato, Natsumi Araya, Junki Koike, Mamoru Tadokoro, Noboru Suzuki, Kazuhiro Nagata, Haruki Senoo, Scott L. Friedman, Kusuki Nishioka, Yoshihisa Yamano, Fumio Itoh, Toshihiro Nakajima

PLoS One. 2010; 5(10): e13590. Published online 2010 Oct 25. doi: 10.1371/journal.pone.0013590

PMCID:: PMC2963597

Article PDF–510K

Select item 108733448.

SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex

Liangguang Leo Lin, Huilun Helen Wang, Brent Pederson, Xiaoqiong Wei, Mauricio Torres, You Lu, Zexin Jason Li, Xiaodan Liu, Hancheng Mao, Hui Wang, Linyao Elina Zhou, Zhen Zhao, Shengyi Sun, Ling Qi

Nat Commun. 2024; 15: 1440. Published online 2024 Feb 16. doi: 10.1038/s41467-024-45633-0

Correction in:: Nat Commun. 2024; 15: 3241.

PMCID:: PMC10873344

Article PDF–7.3M

Select item 106931559.

Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation

Bing Dai, Si Liu, Wenxin Shen, Li Chen, Qianlan Zhou, Lina Han, Qinzhen Zhang, Lishen Shan

Biol Res. 2023; 56: 64. Published online 2023 Dec 2. doi: 10.1186/s40659-023-00478-7

PMCID:: PMC10693155

Article PDF–5.2M

Select item 1040877110.

SYVN1 Promotes STAT3 Protein Ubiquitination and Exerts Antiangiogenesis Effects in Retinopathy of Prematurity Development

Shimei Chen, Jian Zhang, Dandan Sun, Yidong Wu, Junwei Fang, Xiaoling Wan, Shenping Li, Shuchang Zhang, Qing Gu, Qing Shao, Jun Dong, Xun Xu, Fang Wei, Qiao Sun

Invest Ophthalmol Vis Sci. 2023 Aug; 64(11): 8. Published online 2023 Aug 4. doi: 10.1167/iovs.64.11.8

PMCID:: PMC10408771

Article PDF–8.1M

Select item 984843111.

The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development

Eui-Seon Lee, Yam Prasad Aryal, Tae-Young Kim, Elina Pokharel, Ji-Youn Kim, Hitoshi Yamamoto, Chang-Hyeon An, Seo-Young An, Jae-Kwang Jung, Youngkyun Lee, Jung-Hong Ha, Wern-Joo Sohn, Jae-Young Kim

Front Physiol. 2022; 13: 1079355. Published online 2023 Jan 4. doi: 10.3389/fphys.2022.1079355

PMCID:: PMC9848431

Article PDF–4.4M

Select item 648351112.

The E3 ligase Hrd1 stabilizes Tregs by antagonizing inflammatory cytokine–induced ER stress response

Yuanming Xu, Johanna Melo-Cardenas, Yana Zhang, Isabella Gau, Juncheng Wei, Elena Montauti, Yusi Zhang, Beixue Gao, Hongjian Jin, Zhaolin Sun, Sang-Myeong Lee, Deyu Fang

JCI Insight. 2019 Mar 7; 4(5): e121887. Published online 2019 Mar 7. doi: 10.1172/jci.insight.121887

PMCID:: PMC6483511

Article PDF–1.8M

Select item 295552213.

Role of Interleukin 17 in Arthritis Chronicity through Survival of Synoviocytes via Regulation of Synoviolin Expression

Myew-Ling Toh, Gaelle Gonzales, Marije I. Koenders, Anne Tournadre, David Boyle, Erik Lubberts, Yuan Zhou, Gary S. Firestein, Wim B. van den Berg, Pierre Miossec

PLoS One. 2010; 5(10): e13416. Published online 2010 Oct 15. doi: 10.1371/journal.pone.0013416

PMCID:: PMC2955522

Article PDF–6.7M

Select item 119026614.

Identification of a Crucial Site for Synoviolin Expression

Kaneyuki Tsuchimochi, Naoko Yagishita, Satoshi Yamasaki, Tetsuya Amano, Yukihiro Kato, Ko-ichi Kawahara, Satoko Aratani, Hidetoshi Fujita, Fengyun Ji, Akiko Sugiura, Toshihiko Izumi, Asako Sugamiya, Ikuro Maruyama, Akiyoshi Fukamizu, Setsuro Komiya, Kusuki Nishioka, Toshihiro Nakajima

Mol Cell Biol. 2005 Aug; 25(16): 7344–7356. doi: 10.1128/MCB.25.16.7344-7356.2005

PMCID:: PMC1190266

Article PDF–768K

Select item 21808015.

Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy

Tetsuya Amano, Satoshi Yamasaki, Naoko Yagishita, Kaneyuki Tsuchimochi, Hiroshi Shin, Ko-ichi Kawahara, Satoko Aratani, Hidetoshi Fujita, Lei Zhang, Rie Ikeda, Ryoji Fujii, Naoki Miura, Setsuro Komiya, Kusuki Nishioka, Ikuro Maruyama, Akiyoshi Fukamizu, Toshihiro Nakajima

Genes Dev. 2003 Oct 1; 17(19): 2436–2449. doi: 10.1101/gad.1096603

PMCID:: PMC218080

Article PDF–783K

Select item 1037124616.

Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland

Xiaohan Zhang, Crystal Young, Xiao-Hui Liao, Samuel Refetoff, Mauricio Torres, Yaron Tomer, Mihaela Stefan-Lifshitz, Hao Zhang, Dennis Larkin, Deyu Fang, Ling Qi, Peter Arvan

JCI Insight. 2023 Jun 22; 8(12): e169937. Published online 2023 Jun 22. doi: 10.1172/jci.insight.169937

PMCID:: PMC10371246

Article PDF–18M

Select item 955061017.

SEL1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer

Asmita Bhattacharya, Juncheng Wei, Wenxin Song, Beixue Gao, Chunyan Tian, Shuangcheng Alivia Wu, Jian Wang, Ligong Chen, Deyu Fang, Ling Qi

iScience. 2022 Oct 21; 25(10): 105183. Published online 2022 Sep 24. doi: 10.1016/j.isci.2022.105183

PMCID:: PMC9550610

Article PDF–6.4M

Select item 788344418.

Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression

Ya Fan, Jia Wang, Yuemei Xu, Yipin Wang, Tao Song, Xiubin Liang, Feng Jin, Dongming Su

Cell Commun Signal. 2021; 19: 18. Published online 2021 Feb 15. doi: 10.1186/s12964-020-00679-7

Correction in:: Cell Commun Signal. 2021; 19: 111.

PMCID:: PMC7883444

Article PDF–4.9M

Select item 629269219.

The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1

Sam A Menzies, Norbert Volkmar, Dick JH van den Boomen, Richard T Timms, Anna S Dickson, James A Nathan, Paul J Lehner

eLife. 2018; 7: e40009. Published online 2018 Dec 13. doi: 10.7554/eLife.40009

PMCID:: PMC6292692

Article PDF–5.8M

Select item 623633620.

HRD1‐ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination

Juncheng Wei, Lu Chen, Fei Li, Yanzhi Yuan, Yajun Wang, Wanjun Xia, Yuehui Zhang, Yuanming Xu, Zhao Yang, Beixue Gao, Chaozhi Jin, Johanna Melo‐Cardenas, Richard M Green, Hui Pan, Jian Wang, Fuchu He, Kezhong Zhang, Deyu Fang

EMBO J. 2018 Nov 15; 37(22): e98942. Published online 2018 Nov 2. doi: 10.15252/embj.201898942