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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 102085672.

Mitophagy restricts BAX/BAK-independent, Parkin-mediated apoptosis

Giovanni Quarato, Luigi Mari, Nicholas J. Barrows, Mao Yang, Sebastian Ruehl, Mark J. Chen, Cliff S. Guy, Jonathan Low, Taosheng Chen, Douglas R. Green

Sci Adv. 2023 May; 9(21): eadg8156. Published online 2023 May 24. doi: 10.1126/sciadv.adg8156

PMCID:: PMC10208567

Article PDF–1.7M

Select item 95204533.

Evaluating mitophagy in embryonic stem cells by using fluorescence-based imaging

Kun Liu, Xing Li, Zheng Li, Jiani Cao, Xiaoyan Li, Youqing Xu, Lei Liu, Tongbiao Zhao

Front Cell Dev Biol. 2022; 10: 910464. Published online 2022 Sep 15. doi: 10.3389/fcell.2022.910464

PMCID:: PMC9520453

Article PDF–1.9M

Select item 51033584.

ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance

Kun Liu, Qian Zhao, Pinglei Liu, Jiani Cao, Jiaqi Gong, Chaoqun Wang, Weixu Wang, Xiaoyan Li, Hongyan Sun, Chao Zhang, Yufei Li, Minggui Jiang, Shaohua Zhu, Qingyuan Sun, Jianwei Jiao, Baoyang Hu, Xiaoyang Zhao, Wei Li, Quan Chen, Qi Zhou, Tongbiao Zhao

Autophagy. 2016; 12(11): 2000–2008. Published online 2016 Aug 11. doi: 10.1080/15548627.2016.1212786

PMCID:: PMC5103358

Article PDF–1.1M

Select item 56933555.

Endothelial cell autophagy maintains shear-stress-induced nitric oxide generation via glycolysis-dependent purinergic signaling to eNOS

Leena P Bharath, Jae Min Cho, Seul-Ki Park, Ting Ruan, Youyou Li, Robert Mueller, Tyler Bean, Van Reese, Russel S Richardson, Jinjin Cai, Ashot Sargsyan, Karla Pires, Pon Velayutham Anandh Babu, Sihem Boudina, Timothy E Graham, J David Symons

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Sep; 37(9): 1646–1656. Published online 2017 Jul 6. doi: 10.1161/ATVBAHA.117.309510

PMCID:: PMC5693355

Article PDF–2.8M

Select item 55964276.

High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1

Pinglei Liu, Kun Liu, Haifeng Gu, Weixu Wang, Jiaqi Gong, Yingjie Zhu, Qian Zhao, Jiani Cao, Chunseng Han, Fei Gao, Quan Chen, Wei Li, Jianwei Jiao, Baoyang Hu, Qi Zhou, Tongbiao Zhao

Cell Death Differ. 2017 Oct; 24(10): 1672–1680. Published online 2017 Jun 16. doi: 10.1038/cdd.2017.90

PMCID:: PMC5596427

Article PDF–2.0M

Select item 44582187.

A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion

Yuxuan Miao, Guojie Li, Xiaoli Zhang, Haoxing Xu, Soman N. Abraham

Cell. Author manuscript; available in PMC 2016 Jun 4.

Published in final edited form as: Cell. 2015 Jun 4; 161(6): 1306–1319. Published online 2015 May 28. doi: 10.1016/j.cell.2015.05.009

PMCID:: PMC4458218

Article PDF–2.8M

Select item 38950388.

The E2-Like Conjugation Enzyme Atg3 Promotes Binding of IRG and Gbp Proteins to Chlamydia- and Toxoplasma-Containing Vacuoles and Host Resistance

Arun K. Haldar, Anthony S. Piro, Danielle M. Pilla, Masahiro Yamamoto, Jörn Coers

PLoS One. 2014; 9(1): e86684. Published online 2014 Jan 17. doi: 10.1371/journal.pone.0086684

PMCID:: PMC3895038

Article PDF–4.4M

Select item 33276149.

Vaccinia virus leads to ATG12–ATG3 conjugation and deficiency in autophagosome formation

Joseph G. Moloughney, Claude E. Monken, Hanlin Tao, Haiyan Zhang, Janice D. Thomas, Edmund C. Lattime, Shengkan Jin

Autophagy. 2011 Dec 1; 7(12): 1434–1447. doi: 10.4161/auto.7.12.17793

PMCID:: PMC3327614

Article PDF–3.6M

Select item 680293910.

Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk

Jinjin Cai, Karla M. Pires, Maroua Ferhat, Bhagirath Chaurasia, Ma´rcio A. Buffolo, Rana Smalling, Ashot Sargsyan, Donald L. Atkinson, Scott A. Summers, Timothy E. Graham, Sihem Boudina

Cell Rep. Author manuscript; available in PMC 2019 Oct 21.

Published in final edited form as: Cell Rep. 2018 Nov 13; 25(7): 1708–1717.e5. doi: 10.1016/j.celrep.2018.10.040

PMCID:: PMC6802939

Article PDF–2.1M

Select item 577433311.

Suppression of FIP200 and autophagy by tumor-derived lactate promotes naïve T cell apoptosis and affects tumor immunity

Houjun Xia, Wei Wang, Joel Crespo, Ilona Kryczek, Wei Li, Shuang Wei, Zhaoqun Bian, Tomasz Maj, Mingxiao He, Rebecca J. Liu, Youwen He, Ramandeep Rattan, Adnan Munkarah, Jun-Lin Guan, Weiping Zou

Sci Immunol. Author manuscript; available in PMC 2018 Jan 19.

Published in final edited form as: Sci Immunol. 2017 Nov 17; 2(17): eaan4631. doi: 10.1126/sciimmunol.aan4631

PMCID:: PMC5774333

Article PDF–3.6M

Select item 352855712.

Autophagy hijacked through viroporin-activated calcium/calmodulin-dependent kinase kinase-β signaling is required for rotavirus replication

Sue E. Crawford, Joseph M. Hyser, Budi Utama, Mary K. Estes

Proc Natl Acad Sci U S A. 2012 Dec 11; 109(50): E3405–E3413. Published online 2012 Nov 26. doi: 10.1073/pnas.1216539109

PMCID:: PMC3528557

Article PDF–1.4M

Select item 257515613.

The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice

Yu-shin Sou, Satoshi Waguri, Jun-ichi Iwata, Takashi Ueno, Tsutomu Fujimura, Taichi Hara, Naoki Sawada, Akane Yamada, Noboru Mizushima, Yasuo Uchiyama, Eiki Kominami, Keiji Tanaka, Masaaki Komatsu

Mol Biol Cell. 2008 Nov; 19(11): 4762–4775. doi: 10.1091/mbc.E08-03-0309

PMCID:: PMC2575156

Article PDF–2.3M

Select item 575883014.

Oxidation of Atg3 and Atg7 mediates inhibition of autophagy

Karen Frudd, Thomas Burgoyne, Joseph Robert Burgoyne

Nat Commun. 2018; 9: 95. Published online 2018 Jan 8. doi: 10.1038/s41467-017-02352-z

PMCID:: PMC5758830

Article PDF–2.9M

Select item 560267415.

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of T_H9 cells

Thaiz Rivera Vargas, Zhijian Cai, Yingying Shen, Magalie Dosset, Isis Benoit-Lizon, Tiffany Martin, Aurélie Roussey, Richard A. Flavell, François Ghiringhelli, Lionel Apetoh

Nat Commun. 2017; 8: 559. Published online 2017 Sep 15. doi: 10.1038/s41467-017-00468-w

PMCID:: PMC5602674

Article PDF–1.2M

Select item 488950616.

Atg5 is essential for the development and survival of innate lymphocytes

Timothy E. O’Sullivan, Clair D. Geary, Orr-El Weizman, Theresa L. Geiger, Moritz Rapp, Gerald W. Dorn, II, Michael Overholtzer, Joseph C. Sun

Cell Rep. Author manuscript; available in PMC 2016 Jun 2.

Published in final edited form as: Cell Rep. 2016 May 31; 15(9): 1910–1919. Published online 2016 May 19. doi: 10.1016/j.celrep.2016.04.082

PMCID:: PMC4889506

Article PDF–2.4M

Select item 483518817.

Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1

Wei Jia, Ming-Xiao He, Ian X McLeod, Jian Guo, Dong Ji, You-Wen He

Autophagy. 2015 Dec; 11(12): 2335–2345. Published online 2015 Nov 16. doi: 10.1080/15548627.2015.1110666

PMCID:: PMC4835188

Article PDF–779K

Select item 573762618.

BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory

Timothy E. O’Sullivan, Lexus R. Johnson, Helen H. Kang, Joseph C. Sun

Immunity. Author manuscript; available in PMC 2017 Dec 20.

Published in final edited form as: Immunity. 2015 Aug 18; 43(2): 331–342. Published online 2015 Aug 4. doi: 10.1016/j.immuni.2015.07.012

PMCID:: PMC5737626

Article PDF–1.5M

Select item 493299319.

Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity

Owen M. Siggs, Alexander Stockenhuber, Mukta Deobagkar-Lele, Katherine R. Bull, Tanya L. Crockford, Bethany L. Kingston, Greg Crawford, Consuelo Anzilotti, Violetta Steeples, Sahar Ghaffari, Gabor Czibik, Mohamed Bellahcene, Hugh Watkins, Houman Ashrafian, Benjamin Davies, Angela Woods, David Carling, Arash Yavari, Bruce Beutler, Richard J. Cornall

Proc Natl Acad Sci U S A. 2016 Jun 28; 113(26): E3706–E3715. Published online 2016 Jun 14. doi: 10.1073/pnas.1607592113

PMCID:: PMC4932993

Article PDF–2.0M

Select item 434487420.

ATG12-ATG3 Interacts with Alix to Promote Basal Autophagic Flux and Late Endosome Function

Lyndsay Murrow, Ritu Malhotra, Jayanta Debnath

Nat Cell Biol. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Nat Cell Biol. 2015 Mar; 17(3): 300–310. Published online 2015 Feb 16. doi: 10.1038/ncb3112

PMCID:: PMC4344874

Article PDF–2.4M

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