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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 101638242.

Excessive Mechanotransduction in Sensory Neurons Causes Joint Contractures

Shang Ma, Adrienne E. Dubin, Luis O. Romero, Meaghan Loud, Alexandra Salazar, Sarah Chu, Nikola Klier, Sameer Masri, Yunxiao Zhang, Yu Wang, Alex T. Chesler, Katherine A. Wilkinson, Valeria Vásquez, Kara L. Marshall, Ardem Patapoutian

Science. Author manuscript; available in PMC 2023 May 6.

Published in final edited form as: Science. 2023 Jan 13; 379(6628): 201–206. Published online 2023 Jan 12. doi: 10.1126/science.add3598

PMCID:: PMC10163824

Article PDF–1.7M

Select item 96882423.

Midpalatal Suture: Single-Cell RNA-Seq Reveals Intramembrane Ossification and Piezo2 Chondrogenic Mesenchymal Cell Involvement

Lu Gao, Tiansong Xu, Liqi Zhang, Yuchen Li, Tianxing Yan, Guoxia Yu, Feng Chen

Cells. 2022 Nov; 11(22): 3585. Published online 2022 Nov 12. doi: 10.3390/cells11223585

PMCID:: PMC9688242

Article PDF–3.1M

Select item 91737514.

Focused ultrasound excites action potentials in mammalian peripheral neurons in part through the mechanically gated ion channel PIEZO2

Benjamin U. Hoffman, Yoshichika Baba, Stephen A. Lee, Chi-Kun Tong, Elisa E. Konofagou, Ellen A. Lumpkin

Proc Natl Acad Sci U S A. 2022 May 24; 119(21): e2115821119. Published online 2022 May 17. doi: 10.1073/pnas.2115821119

PMCID:: PMC9173751

Article PDF–2.5M

Select item 76730065.

Piezo2 Mediates Low-Threshold Mechanically Evoked Pain in the Cornea

Jorge Fernández-Trillo, Danny Florez-Paz, Almudena Íñigo-Portugués, Omar González-González, Ana Gómez del Campo, Alejandro González, Félix Viana, Carlos Belmonte, Ana Gomis

J Neurosci. 2020 Nov 18; 40(47): 8976–8993. doi: 10.1523/JNEUROSCI.0247-20.2020

PMCID:: PMC7673006

Article PDF–4.9M

Select item 72022116.

Gi‐coupled receptor activation potentiates Piezo2 currents via Gβγ

John Smith Del Rosario, Yevgen Yudin, Songxue Su, Cassandra M Hartle, Tooraj Mirshahi, Tibor Rohacs

EMBO Rep. 2020 May 6; 21(5): e49124. Published online 2020 Mar 29. doi: 10.15252/embr.201949124

PMCID:: PMC7202211

Article PDF–1.4M

Select item 51901247.

Piezo2 protein: A novel regulator of tumor angiogenesis and hyperpermeability

Hong Yang, Chang Liu, Rong-Mei Zhou, Jin Yao, Xiu-Miao Li, Yi Shen, Hong Cheng, Jun Yuan, Biao Yan, Qin Jiang

Oncotarget. 2016 Jul 12; 7(28): 44630–44643. Published online 2016 Jun 17. doi: 10.18632/oncotarget.10134

PMCID:: PMC5190124

Article PDF–13M

Select item 109192518.

Caldendrin Is a Repressor of PIEZO2 Channels and Touch Sensation in Mice

Josue A. Lopez, Luis O. Romero, Wai-Lin Kaung, J. Wesley Maddox, Valeria Vásquez, Amy Lee

J Neurosci. 2024 Mar 6; 44(10): e1402232023. doi: 10.1523/JNEUROSCI.1402-23.2023

PMCID:: PMC10919251

Article PDF–3.7M

Select item 101488229.

Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis

Alia M. Obeidat, Matthew J. Wood, Natalie S. Adamczyk, Shingo Ishihara, Jun Li, Lai Wang, Dongjun Ren, David A. Bennett, Richard J. Miller, Anne-Marie Malfait, Rachel E. Miller

Nat Commun. 2023; 14: 2479. Published online 2023 Apr 29. doi: 10.1038/s41467-023-38241-x

PMCID:: PMC10148822

Article PDF–2.7M

Select item 997796310.

Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome

Luis O. Romero, Rebeca Caires, A. Kaitlyn Victor, Juanma Ramirez, Francisco J. Sierra-Valdez, Patrick Walsh, Vincent Truong, Jungsoo Lee, Ugo Mayor, Lawrence T. Reiter, Valeria Vásquez, Julio F. Cordero-Morales

Nat Commun. 2023; 14: 1167. Published online 2023 Mar 1. doi: 10.1038/s41467-023-36818-0

PMCID:: PMC9977963

Article PDF–33M

Select item 929416311.

Electroacupuncture Attenuates Post-Inflammatory IBS-Associated Visceral and Somatic Hypersensitivity and Correlates With the Regulatory Mechanism of Epac1–Piezo2 Axis

Jing Guo, Lu Chen, Yu-hang Wang, Ya-fang Song, Zhan-hao Zhao, Ting-ting Zhao, Zhi-ying Lin, Dong-mei Gu, Yun-qi Liu, Yong-jun Peng, Li-xia Pei, Jian-hua Sun

Front Endocrinol (Lausanne) 2022; 13: 918652. Published online 2022 Jul 5. doi: 10.3389/fendo.2022.918652

PMCID:: PMC9294163

Article PDF–9.9M

Select item 928007212.

TMEM120A/TACAN inhibits mechanically activated PIEZO2 channels

John Smith Del Rosario, Matthew Gabrielle, Yevgen Yudin, Tibor Rohacs

J Gen Physiol. 2022 Aug 1; 154(8): e202213164. Published online 2022 Jul 12. doi: 10.1085/jgp.202213164

PMCID:: PMC9280072

Article PDF–5.4M

Select item 911401213.

Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes

Benjamin Kloth, Giulia Mearini, Florian Weinberger, Justus Stenzig, Birgit Geertz, Jutta Starbatty, Diana Lindner, Udo Schumacher, Hermann Reichenspurner, Thomas Eschenhagen, Marc N. Hirt

Sci Rep. 2022; 12: 8193. Published online 2022 May 17. doi: 10.1038/s41598-022-12085-9

PMCID:: PMC9114012

Article PDF–2.1M

Select item 879233114.

Specialized Mechanosensory Epithelial Cells in Mouse Gut Intrinsic Tactile Sensitivity

Anthony J. Treichel, Isabelle Finholm, Kaitlyn R. Knutson, Constanza Alcaino, Sara T. Whiteman, Matthew R. Brown, Aleksey Matveyenko, Andrew Wegner, Halil Kacmaz, Arnaldo Mercado-Perez, Gabriella Bedekovicsne Gajdos, Tamas Ordog, Madhusudan Grover, Joseph Szurzewski, David R. Linden, Gianrico Farrugia, Arthur Beyder

Gastroenterology. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Gastroenterology. 2022 Feb; 162(2): 535–547.e13. Published online 2021 Oct 22. doi: 10.1053/j.gastro.2021.10.026

PMCID:: PMC8792331

Article PDF–1.8M

Select item 852564315.

Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception

Marianela G. Dalghi, Wily G. Ruiz, Dennis R. Clayton, Nicolas Montalbetti, Stephanie L. Daugherty, Jonathan M. Beckel, Marcelo D. Carattino, Gerard Apodaca

JCI Insight. 2021 Oct 8; 6(19): e152984. Published online 2021 Oct 8. doi: 10.1172/jci.insight.152984

PMCID:: PMC8525643

Article PDF–8.2M

Select item 821950616.

Piezo2 downregulation via the Cre-lox system affects aqueous humor dynamics in mice

Jingwang Fang, Fei Hou, Shen Wu, Yani Liu, Linna Wang, Jingxue Zhang, Ningli Wang, Kewei Wang, Wei Zhu

Mol Vis. 2021; 27: 354–364. Published online 2021 May 20.

PMCID:: PMC8219506

Article PDF–3.4M

Select item 670998617.

The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice

Swetha E. Murthy, Meaghan C. Loud, Ihab Daou, Kara L. Marshall, Frederick Schwaller, Johannes Kühnemund, Allain G. Francisco, William T. Keenan, Adrienne E. Dubin, Gary R. Lewin, Ardem Patapoutian

Sci Transl Med. Author manuscript; available in PMC 2019 Aug 26.

Published in final edited form as: Sci Transl Med. 2018 Oct 10; 10(462): eaat9897. doi: 10.1126/scitranslmed.aat9897

PMCID:: PMC6709986

Article PDF–918K

Select item 602845418.

Somatosensory innervation of the oral mucosa of adult and aging mice

Yalda Moayedi, Lucia F. Duenas-Bianchi, Ellen A. Lumpkin

Sci Rep. 2018; 8: 9975. Published online 2018 Jul 2. doi: 10.1038/s41598-018-28195-2

PMCID:: PMC6028454

Article PDF–3.9M

Select item 564637819.

Transduction of repetitive mechanical stimuli by Piezo1 and Piezo2 ion channels

Amanda H. Lewis, Alisa F. Cui, Malcolm F. McDonald, Jörg Grandl

Cell Rep. Author manuscript; available in PMC 2017 Oct 18.

Published in final edited form as: Cell Rep. 2017 Jun 20; 19(12): 2572–2585. doi: 10.1016/j.celrep.2017.05.079

PMCID:: PMC5646378

Article PDF–1.0M

Select item 519973320.

Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces

Fan Wang, Kaitlyn Knutson, Constanza Alcaino, David R. Linden, Simon J. Gibbons, Purna Kashyap, Madhusudan Grover, Richard Oeckler, Philip A. Gottlieb, Hui Joyce Li, Andrew B. Leiter, Gianrico Farrugia, Arthur Beyder

J Physiol. 2017 Jan 1; 595(1): 79–91. Published online 2016 Aug 13. doi: 10.1113/JP272718

PMCID:: PMC5199733

Article PDF–981K

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