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Select item 66238601.

PALS1 Is Essential for Retinal Pigment Epithelium Structure and Neural Retina Stratification

Bokyung Park, Celso Henrique Alves, Ditte M. Lundvig, Naoyuki Tanimoto, Susanne C. Beck, Gesine Huber, Fabrice Richard, Jan Klooster, Till F. M. Andlauer, Eric C. Swindell, Milan Jamrich, André Le Bivic, Mathias W. Seeliger, Jan Wijnholds

J Neurosci. 2011 Nov 23; 31(47): 17230–17241. doi: 10.1523/JNEUROSCI.4430-11.2011

PMCID:: PMC6623860

Article PDF–2.2M

Select item 81877092.

Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1

Jin Chai, Yuanheng Cai, Changxu Pang, Liguo Wang, Sean McSweeney, John Shanklin, Qun Liu

Nat Commun. 2021; 12: 3433. Published online 2021 Jun 8. doi: 10.1038/s41467-021-23533-x

PMCID:: PMC8187709

Article PDF–1.3M

Select item 80946003.

Pals1 prevents Rac1-dependent colorectal cancer cell metastasis by inhibiting Arf6

Simona Mareike Lüttgenau, Christin Emming, Thomas Wagner, Julia Harms, Justine Guske, Katrin Weber, Ute Neugebauer, Rita Schröter, Olga Panichkina, Zoltán Pethő, Florian Weber, Albrecht Schwab, Anja Kathrin Wege, Pavel Nedvetsky, Michael P. Krahn

Mol Cancer. 2021; 20: 74. Published online 2021 May 4. doi: 10.1186/s12943-021-01354-2

PMCID:: PMC8094600

Article PDF–1.6M

Select item 79707984.

Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins

Ettore Lo Cascio, Angelo Toto, Gabriele Babini, Flavio De Maio, Maurizio Sanguinetti, Alvaro Mordente, Stefano Della Longa, Alessandro Arcovito

Comput Struct Biotechnol J. 2021; 19: 1838–1847. Published online 2021 Mar 18. doi: 10.1016/j.csbj.2021.03.014

PMCID:: PMC7970798

Article PDF–2.2M

Select item 43563665.

Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove

Marina E. Ivanova, Georgina C. Fletcher, Nicola O’Reilly, Andrew G. Purkiss, Barry J. Thompson, Neil Q. McDonald

Acta Crystallogr D Biol Crystallogr. 2015 Mar 1; 71(Pt 3): 555–564. Published online 2015 Feb 26. doi: 10.1107/S139900471402776X

PMCID:: PMC4356366

Article PDF–2.0M

Select item 32124726.

Crystallization and preliminary X-ray data collection of the L27_PATJ–(L27N,L27C)_Pals1–L27_MALS tripartite complex

Jinxiu Zhang, Xue Yang, Yuequan Shen, Jiafu Long

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Nov 1; 67(Pt 11): 1443–1447. Published online 2011 Oct 27. doi: 10.1107/S174430911103689X

PMCID:: PMC3212472

Article PDF–611K

Select item 29624567.

Polycystin-2 Activity Is Controlled by Transcriptional Coactivator with PDZ Binding Motif and PALS1-associated Tight Junction Protein

Kerstin Duning, Deike Rosenbusch, Marc A. Schlüter, Yuemin Tian, Karl Kunzelmann, Nina Meyer, Ulf Schulze, Arseni Markoff, Hermann Pavenstädt, Thomas Weide

J Biol Chem. 2010 Oct 29; 285(44): 33584–33588. Published online 2010 Sep 10. doi: 10.1074/jbc.C110.146381

PMCID:: PMC2962456

Article PDF–672K

Select item 81960108.

Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain

Airah Javorsky, Patrick O. Humbert, Marc Kvansakul

Commun Biol. 2021; 4: 724. Published online 2021 Jun 11. doi: 10.1038/s42003-021-02250-7

PMCID:: PMC8196010

Article PDF–1.6M

Select item 74614389.

Comparing the binding properties of peptides mimicking the Envelope protein of SARS‐CoV and SARS‐CoV‐2 to the PDZ domain of the tight junction‐associated PALS1 protein

Angelo Toto, Sana Ma, Francesca Malagrinò, Lorenzo Visconti, Livia Pagano, Kristian Stromgaard, Stefano Gianni

Protein Sci. 2020 Oct; 29(10): 2038–2042. Published online 2020 Sep 8. doi: 10.1002/pro.3936

PMCID:: PMC7461438

Article PDF–791K

Select item 538068210.

The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy

Peter M. Quinn, Lucie P. Pellissier, Jan Wijnholds

Front Neurosci. 2017; 11: 175. Published online 2017 Apr 5. doi: 10.3389/fnins.2017.00175

PMCID:: PMC5380682

Article PDF–3.7M

Select item 332283111.

Structure of an L27 Domain Heterotrimer from Cell Polarity Complex Patj/Pals1/Mals2 Reveals Mutually Independent L27 Domain Assembly Mode

Jinxiu Zhang, Xue Yang, Zheng Wang, Hao Zhou, Xingqiao Xie, Yuequan Shen, Jiafu Long

J Biol Chem. 2012 Mar 30; 287(14): 11132–11140. Published online 2012 Feb 15. doi: 10.1074/jbc.M111.321216

PMCID:: PMC3322831

Article PDF–2.4M

Select item 306818112.

Participation of the Cell Polarity Protein PALS1 to T-Cell Receptor-Mediated NF-κB Activation

Gabrielle Carvalho, Konstantinos Poalas, Catherine Demian, Emeline Hatchi, Aimé Vazquez, Nicolas Bidère

PLoS One. 2011; 6(3): e18159. Published online 2011 Mar 30. doi: 10.1371/journal.pone.0018159

PMCID:: PMC3068181

Article PDF–1.1M

Select item 298209113.

The SARS Coronavirus E Protein Interacts with PALS1 and Alters Tight Junction Formation and Epithelial Morphogenesis

Kim-Tat Teoh, Yu-Lam Siu, Wing-Lim Chan, Marc A. Schlüter, Chia-Jen Liu, J. S. Malik Peiris, Roberto Bruzzone, Benjamin Margolis, Béatrice Nal

Mol Biol Cell. 2010 Nov 15; 21(22): 3838–3852. doi: 10.1091/mbc.E10-04-0338

PMCID:: PMC2982091

Article

Select item 214027514.

Internal Recognition Through PDZ Domain Plasticity in the Par-6 - Pals1 Complex

Rhiannon R. Penkert, Heather M. DiVittorio, Kenneth E. Prehoda

Nat Struct Mol Biol. Author manuscript; available in PMC 2007 Dec 17.

Published in final edited form as: Nat Struct Mol Biol. 2004 Nov; 11(11): 1122–1127. Published online 2004 Oct 10. doi: 10.1038/nsmb839

PMCID:: PMC2140275

Article PDF–1.1M

Select item 1001457515.

Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion

Julia Harms, Simona Mareike Lüttgenau, Christin Emming, Justine Guske, Katrin Weber, Thomas Wagner, Larissa Schowe, Pavel Nedvetsky, Michael P. Krahn

Cancer Gene Ther. 2023; 30(3): 497–506. Published online 2022 Dec 9. doi: 10.1038/s41417-022-00570-2

PMCID:: PMC10014575

Article PDF–5.0M

Select item 217325416.

The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost

Michael H. Roh, Olga Makarova, Chia-Jen Liu, Shin, Seonok Lee, Stephanie Laurinec, Meera Goyal, Roger Wiggins, Ben Margolis

J Cell Biol. 2002 Apr 1; 157(1): 161–172. doi: 10.1083/jcb.200109010

PMCID:: PMC2173254

Article PDF–909K

Select item 961020717.

A Syntenin Inhibitor Blocks Endosomal Entry of SARS-CoV-2 and a Panel of RNA Viruses

Richard Lindqvist, Caroline Benz, Vita Sereikaite, Lars Maassen, Louise Laursen, Per Jemth, Kristian Strømgaard, Ylva Ivarsson, Anna K. Överby

Viruses. 2022 Oct; 14(10): 2202. Published online 2022 Oct 6. doi: 10.3390/v14102202

PMCID:: PMC9610207

Article PDF–1.5M

Select item 890912718.

Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins

Yanlei Zhu, Flavio Alvarez, Nicolas Wolff, Ariel Mechaly, Sébastien Brûlé, Benoit Neitthoffer, Sandrine Etienne-Manneville, Ahmed Haouz, Batiste Boëda, Célia Caillet-Saguy

Front Microbiol. 2022; 13: 829094. Published online 2022 Feb 23. doi: 10.3389/fmicb.2022.829094

PMCID:: PMC8909127

Article PDF–3.1M

Select item 458591519.

CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium

Antonio E. Paniagua, Saúl Herranz-Martín, David Jimeno, Ángela M. Jimeno, Saray López-Benito, Juan Carlos Arévalo, Almudena Velasco, José Aijón, Concepción Lillo

Sci Rep. 2015; 5: 14504. Published online 2015 Sep 25. doi: 10.1038/srep14504