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Select item 75203341.

Knockdown of endogenous RNF4 exacerbates ischaemia‐induced cardiomyocyte apoptosis in mice

Fang Qiu, Yanna Han, Xiaoqi Shao, Petro Paulo, Wenyue Li, Mengying Zhu, Nannan Tang, Shuaili Guo, Yibing Chen, Han Wu, Dan Zhao, Yu Liu, Wenfeng Chu

J Cell Mol Med. 2020 Sep; 24(17): 9545–9559. Published online 2020 Jul 28. doi: 10.1111/jcmm.15363

PMCID:: PMC7520334

Article PDF–2.4M

Select item 74227212.

Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications

Carl C. Ward, Jordan I. Kleinman, Scott M. Brittain, Patrick S. Lee, Clive Yik Sham Chung, Kenneth Kim, Yana Petri, Jason R. Thomas, John A. Tallarico, Jeffrey M. McKenna, Markus Schirle, Daniel K. Nomura

ACS Chem Biol. Author manuscript; available in PMC 2020 Nov 15.

Published in final edited form as: ACS Chem Biol. 2019 Nov 15; 14(11): 2430–2440. Published online 2019 May 13. doi: 10.1021/acschembio.8b01083

PMCID:: PMC7422721

Article PDF–1.7M

Select item 54130873.

The Epstein-Barr virus miR-BHRF1-1 targets RNF4 during productive infection to promote the accumulation of SUMO conjugates and the release of infectious virus

Jinlin Li, Simone Callegari, Maria G. Masucci

PLoS Pathog. 2017 Apr; 13(4): e1006338. Published online 2017 Apr 17. doi: 10.1371/journal.ppat.1006338

PMCID:: PMC5413087

Article PDF–3.7M

Select item 91359434.

DNA damage-induced degradation of Sp1 promotes cellular senescence

Michelle L. Swift, Christian Sell, Jane Azizkhan-Clifford

GeroScience. 2022 Apr; 44(2): 683–698. Published online 2021 Sep 22. doi: 10.1007/s11357-021-00456-5

PMCID:: PMC9135943

Article PDF–3.5M

Select item 60027015.

E1B-55K-Mediated Regulation of RNF4 SUMO-Targeted Ubiquitin Ligase Promotes Human Adenovirus Gene Expression

Sarah Müncheberg, Ron T. Hay, Wing H. Ip, Tina Meyer, Christina Weiß, Jara Brenke, Sawinee Masser, Kamyar Hadian, Thomas Dobner, Sabrina Schreiner

J Virol. 2018 Jul 1; 92(13): e00164-18. Prepublished online 2018 Apr 25. Published online 2018 Jun 13. doi: 10.1128/JVI.00164-18

PMCID:: PMC6002701

Article PDF–3.0M

Select item 50420186.

RNF4-mediated SUMOylation is essential for NDRG2 suppression of lung adenocarcinoma

Jicheng Tantai, Xufeng Pan, Dingzhong Hu

Oncotarget. 2016 May 3; 7(18): 26837–26843. Published online 2016 Apr 9. doi: 10.18632/oncotarget.8663

PMCID:: PMC5042018

Article PDF–4.2M

Select item 48689787.

Loss of ubiquitin E2 Ube2w rescues hypersensitivity of Rnf4 mutant cells to DNA damage

Jean-François Maure, Sandra C. Moser, Ellis G. Jaffray, Arno F. Alpi, Ronald T. Hay

Sci Rep. 2016; 6: 26178. Published online 2016 May 17. doi: 10.1038/srep26178

PMCID:: PMC4868978

Article PDF–1.4M

Select item 42563158.

RING Finger Protein 4 (RNF4) Derepresses Gene Expression from DNA Methylation

Yu Wang

J Biol Chem. 2014 Dec 5; 289(49): 33808–33813. Published online 2014 Oct 29. doi: 10.1074/jbc.C114.611558

PMCID:: PMC4256315

Article PDF–1.6M

Select item 33067069.

Gold nanoparticles as a platform for creating a multivalent poly-SUMO chain inhibitor that also augments ionizing radiation

Yi-Jia Li, Angela L. Perkins, Yang Su, Yuelong Ma, Loren Colson, David A. Horne, Yuan Chen

Proc Natl Acad Sci U S A. 2012 Mar 13; 109(11): 4092-4097. Published online 2012 Mar 2. doi: 10.1073/pnas.1109131109

PMCID:: PMC3306706

Article PDF–1.2M

Select item 327735310.

The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax

Kimberly A. Fryrear, Xin Guo, Oliver Kerscher, O. John Semmes

Blood. 2012 Feb 2; 119(5): 1173–1181. Prepublished online 2011 Nov 21. doi: 10.1182/blood-2011-06-358564

PMCID:: PMC3277353

Article

Select item 950936011.

RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival

Rostislav Novak, Yamen Abu Ahmad, Michael Timaner, Eliya Bitman-Lotan, Avital Oknin-Vaisman, Roi Horwitz, Oliver Hartmann, Michaela Reissland, Viktoria Buck, Mathias Rosenfeldt, David Nikomarov, Markus Elmar Diefenbacher, Yuval Shaked, Amir Orian

Cell Death Dis. 2022 Sep; 13(9): 820. Published online 2022 Sep 24. doi: 10.1038/s41419-022-05262-1

PMCID:: PMC9509360

Article PDF–4.2M

Select item 863311812.

RNF4 Regulates the BLM Helicase in Recovery From Replication Fork Collapse

Nathan Ellis, Jianmei Zhu, Mary K Yagle, Wei-Chih Yang, Jing Huang, Alexander Kwako, Michael M. Seidman, Michael J. Matunis

Front Genet. 2021; 12: 753535. Published online 2021 Nov 12. doi: 10.3389/fgene.2021.753535

PMCID:: PMC8633118

Article PDF–2.4M

Select item 730709013.

Effect of SUMO-SIM Interaction on the ICP0-Mediated Degradation of PML Isoform II and Its Associated Proteins in Herpes Simplex Virus 1 Infection

Behdokht Jan Fada, Elie Kaadi, Subodh Kumar Samrat, Yi Zheng, Haidong Gu

J Virol. 2020 Jun; 94(12): e00470-20. Prepublished online 2020 Apr 15. Published online 2020 Jun 1. doi: 10.1128/JVI.00470-20

PMCID:: PMC7307090

Article PDF–2.2M

Select item 576838114.

Factor inhibiting HIF1–A novel target of SUMOylation in the human placenta

Julien Sallais, Sruthi Alahari, Andrea Tagliaferro, Jayonta Bhattacharjee, Martin Post, Isabella Caniggia

Oncotarget. 2017 Dec 26; 8(69): 114002–114018. Published online 2017 Dec 7. doi: 10.18632/oncotarget.23113

PMCID:: PMC5768381

Article PDF–3.3M

Select item 572418715.

Converging Small Ubiquitin-like Modifier (SUMO) and Ubiquitin Signaling: Improved Methodology Identifies Co-modified Target Proteins

Sabine A. G. Cuijpers, Edwin Willemstein, Alfred C. O. Vertegaal

Mol Cell Proteomics. 2017 Dec; 16(12): 2281–2295. Published online 2017 Sep 26. doi: 10.1074/mcp.TIR117.000152

PMCID:: PMC5724187

Article PDF–1.5M

Select item 569996816.

Respiratory syncytial virus induces NRF2 degradation through a promyelocytic leukemia protein - ring finger protein 4 dependent pathway

Narayana Komaravelli, Maria Ansar, Roberto P. Garofalo, Antonella Casola

Free Radic Biol Med. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Free Radic Biol Med. 2017 Dec; 113: 494–504. Published online 2017 Oct 28. doi: 10.1016/j.freeradbiomed.2017.10.380

PMCID:: PMC5699968

Article PDF–1.4M

Select item 512523817.

RNF4-Dependent Oncogene Activation by Protein Stabilization

Jane J. Thomas, Mona Abed, Julian Heuberger, Rostislav Novak, Yaniv Zohar, Angela P. Beltran Lopez, Julie S. Trausch-Azar, Ma. Xenia G. Ilagan, David Benhamou, Gunnar Dittmar, Raphael Kopan, Walter Birchmeier, Alan L. Schwartz, Amir Orian

Cell Rep. Author manuscript; available in PMC 2016 Nov 28.

Published in final edited form as: Cell Rep. 2016 Sep 20; 16(12): 3388–3400. doi: 10.1016/j.celrep.2016.08.024

PMCID:: PMC5125238

Article PDF–4.3M

Select item 447761218.

Ubiquitin-specific Protease 11 (USP11) Deubiquitinates Hybrid Small Ubiquitin-like Modifier (SUMO)-Ubiquitin Chains to Counteract RING Finger Protein 4 (RNF4)

Ivo A. Hendriks, Joost Schimmel, Karolin Eifler, Jesper V. Olsen, Alfred C. O. Vertegaal

J Biol Chem. 2015 Jun 19; 290(25): 15526–15537. Published online 2015 May 12. doi: 10.1074/jbc.M114.618132

PMCID:: PMC4477612

Article PDF–3.3M

Select item 439649119.

RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway

Jenny Xie, Hyungjin Kim, Lisa A. Moreau, Shannon Puhalla, Judy Garber, Muthana Al Abo, Shunichi Takeda, Alan D. D’Andrea

J Clin Invest. 2015 Apr 1; 125(4): 1523–1532. Published online 2015 Mar 9. doi: 10.1172/JCI79325

PMCID:: PMC4396491

Article PDF–2.3M

Select item 390139520.

Multivalent interactions of the SUMO-interaction motifs in RING finger protein 4 determine the specificity for chains of the SUMO

Kirstin Keusekotten, Veronika N. Bade, Katrin Meyer-Teschendorf, Annie Miriam Sriramachandran, Katrin Fischer-Schrader, Anke Krause, Christiane Horst, Günter Schwarz, Kay Hofmann, R. Jürgen Dohmen, Gerrit J. K. Praefcke

Biochem J. 2014 Jan 1; 457(Pt 1): 207–214. Prepublished online 2013 Oct 23. Published online 2013 Dec 10. doi: 10.1042/BJ20130753