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Select item 96676681.

TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma

Xiaoqin Xu, Ting Sun, Jiexian Jing

BMC Endocr Disord. 2022; 22: 280. Published online 2022 Nov 16. doi: 10.1186/s12902-022-01203-3

PMCID:: PMC9667668

Article PDF–5.4M

Select item 88210722.

Utility of TMPRSS4 as a Prognostic Biomarker and Potential Therapeutic Target in Patients with Gastric Cancer

Hirofumi Tazawa, Takahisa Suzuki, Akihisa Saito, Akira Ishikawa, Toshiaki Komo, Haruki Sada, Norimitsu Shimada, Naoto Hadano, Takashi Onoe, Takeshi Sudo, Yosuke Shimizu, Kazuya Kuraoka, Hirotaka Tashiro

J Gastrointest Surg. 2022; 26(2): 305–313. Published online 2021 Aug 11. doi: 10.1007/s11605-021-05101-2

PMCID:: PMC8821072

Article PDF–2.7M

Select item 79140733.

COVID-19 and SARS-CoV-2 host cell entry mediators: Expression profiling of TMRSS4 in health and disease

Periklis Katopodis, Rachel Kerslake, Julie Davies, Harpal S. Randeva, Kamaljit Chatha, Marcia Hall, Demetrios A. Spandidos, Vladimir Anikin, Andreas Polychronis, Jan L. Robertus, Ioannis Kyrou, Emmanouil Karteris

Int J Mol Med. 2021 Apr; 47(4): 64. Published online 2021 Feb 26. doi: 10.3892/ijmm.2021.4897

PMCID:: PMC7914073

Article PDF–788K

Select item 71733824.

Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment

Ganiou Assani, Julien Segbo, Xiaoyan Yu, Akadiri Yessoufou, Yudi Xiong, Xiong Zhou, Yunfeng Zhou

Asian Pac J Cancer Prev. 2019; 20(12): 3679–3687. doi: 10.31557/APJCP.2019.20.12.3679

PMCID:: PMC7173382

Article PDF–728K

Select item 70216255.

Role of TMPRSS4 Modulation in Breast Cancer Cell Proliferation

Ganiou Assani, Akadiri Yessoufou, Yudi Xiong, Julien Segbo, Xiaoyan Yu, Fuxiang Zhou, Yunfeng Zhou

Asian Pac J Cancer Prev. 2019; 20(6): 1849–1856. doi: 10.31557/APJCP.2019.20.6.1849

PMCID:: PMC7021625

Article PDF–738K

Select item 53604216.

Overexpression of TMPRSS4 promotes tumor proliferation and aggressiveness in breast cancer

Xiao-Mei Li, Wen-Lou Liu, Xu Chen, Ya-Wen Wang, Duan-Bo Shi, Hui Zhang, Ran-Ran Ma, Hai-Ting Liu, Xiang-Yu Guo, Feng Hou, Ming Li, Peng Gao

Int J Mol Med. 2017 Apr; 39(4): 927–935. Published online 2017 Feb 17. doi: 10.3892/ijmm.2017.2893

PMCID:: PMC5360421

Article PDF–1.3M

Select item 53428187.

TMPRSS4 as an emerging potential poor prognostic factor for solid tumors: A systematic review and meta-analysis

Ping Zeng, Peng Zhang, Li-Na Zhou, Min Tang, Yi-Xin Shen, Jun Jin, Ya-Qun Zhu, Min-Bin Chen

Oncotarget. 2016 Nov 15; 7(46): 76327–76336. Published online 2016 Jun 17. doi: 10.18632/oncotarget.10153

PMCID:: PMC5342818

Article PDF–2.4M

Select item 50083988.

Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients

Maria Villalba, Angel Diaz-Lagares, Miriam Redrado, Arrate L. de Aberasturi, Victor Segura, Maria Elena Bodegas, Maria J. Pajares, Ruben Pio, Javier Freire, Javier Gomez-Roman, Luis M. Montuenga, Manel Esteller, Juan Sandoval, Alfonso Calvo

Oncotarget. 2016 Apr 19; 7(16): 22752–22769. Published online 2016 Mar 14. doi: 10.18632/oncotarget.8045

PMCID:: PMC5008398

Article PDF–6.4M

Select item 45071769.

TMPRSS4 facilitates epithelial-mesenchymal transition of hepatocellular carcinoma and is a predictive marker for poor prognosis of patients after curative resection

Cheng-Hao Wang, Zhong-Yi Guo, Ze-Ting Chen, Xu-Ting Zhi, Deng-Ke Li, Zhao-Ru Dong, Zhi-Qiang Chen, San-Yuan Hu, Tao Li

Sci Rep. 2015; 5: 12366. Published online 2015 Jul 20. doi: 10.1038/srep12366

PMCID:: PMC4507176

Article PDF–3.0M

Select item 445359310.

TMPRSS4: an emerging potential therapeutic target in cancer

A L de Aberasturi, A Calvo

Br J Cancer. 2015 Jan 6; 112(1): 4–8. Published online 2014 Sep 9. doi: 10.1038/bjc.2014.403

PMCID:: PMC4453593

Article PDF–647K

Select item 429079811.

Transmembrane Protease Serine 4 Promotes Thyroid Cancer Proliferation via CREB Phosphorylation

Hongyu Guan, Weiwei Liang, Juan Liu, Guohong Wei, Hai Li, Lingling Xiu, Haipeng Xiao, Yanbing Li

Thyroid. 2015 Jan 1; 25(1): 85–94. doi: 10.1089/thy.2014.0155

PMCID:: PMC4290798

Article PDF–979K

Select item 427056112.

Clinical significance of TMPRSS4 in prostate cancer

Guohai Shi, Xiaoqun Yang, Bo Dai, Hailiang Zhang, Yijun Shen, Yao Zhu, Yiping Zhu, Wenjun Xiao, Chunguang Ma, Linguo Wen, Xiaojian Qin, Dalong Cao, Dingwei Ye

Int J Clin Exp Pathol. 2014; 7(11): 8053–8058. Published online 2014 Oct 15.

PMCID:: PMC4270561

Article PDF–462K

Select item 397483113.

TMPRSS4 correlates with colorectal cancer pathological stage and regulates cell proliferation and self-renewal ability

Ao Huang, Houmin Zhou, Hongchao Zhao, Yingjun Quan, Bo Feng, Minhua Zheng

Cancer Biol Ther. 2014 Mar 1; 15(3): 297–304. Published online 2013 Dec 12. doi: 10.4161/cbt.27308

PMCID:: PMC3974831

Article PDF–2.6M

Select item 376579314.

A mutation in the serine protease TMPRSS4 in a novel pediatric neurodegenerative disorder

Piya Lahiry, Lemuel Racacho, Jian Wang, John F Robinson, Gregory B Gloor, C Anthony Rupar, Victoria M Siu, Dennis E Bulman, Robert A Hegele

Orphanet J Rare Dis. 2013; 8: 126. Published online 2013 Aug 17. doi: 10.1186/1750-1172-8-126

PMCID:: PMC3765793

Article PDF–1.3M

Select item 358290315.

Expression of TMPRSS4 in non-small cell lung cancer and its modulation by hypoxia

TRI-HUNG NGUYEN, WILLIAM WEBER, EVIS HAVARI, TIMOTHY CONNORS, REBECCA G. BAGLEY, RAJASHREE McLAREN, PRASHANT R. NAMBIAR, STEPHEN L. MADDEN, BEVERLY A. TEICHER, BRUCE ROBERTS, JOHANNE KAPLAN, SRINIVAS SHANKARA

Int J Oncol. 2012 Sep; 41(3): 829–838. Published online 2012 Jun 12. doi: 10.3892/ijo.2012.1513

PMCID:: PMC3582903

Article PDF–753K

Select item 324253216.

Overexpression of TMPRSS4 in non-small cell lung cancer is associated with poor prognosis in patients with squamous histology

L Larzabal, P A Nguewa, R Pio, D Blanco, B Sanchez, M J Rodríguez, M J Pajares, R Catena, L M Montuenga, A Calvo

Br J Cancer. 2011 Nov 8; 105(10): 1608–1614. Published online 2011 Nov 8. doi: 10.1038/bjc.2011.432

PMCID:: PMC3242532

Article PDF–497K

Select item 681790817.

Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1

Maria Villalba, Esther Redin, Francisco Exposito, Maria Jose Pajares, Cristina Sainz, David Hervas, Elizabeth Guruceaga, Angel Diaz-Lagares, Cristina Cirauqui, Miriam Redrado, Karmele Valencia, Carlos de Andrea, Eloisa Jantus-Lewintre, Carlos Camps, Rafael Lopez-Lopez, Agustin Lahoz, Luis Montuenga, Ruben Pio, Juan Sandoval, Alfonso Calvo

Sci Rep. 2019; 9: 15400. Published online 2019 Oct 28. doi: 10.1038/s41598-019-51066-3

PMCID:: PMC6817908

Article PDF–1.7M

Select item 595872718.

The upregulation of TMPRSS4, partly ascribed to the downregulation of miR-125a-5p, promotes the growth of human lung adenocarcinoma via the NF-κB signaling pathway

Xiaoxi Fan, Yicheng Liang, Yang Liu, Yunpeng Bai, Chunlu Yang, Shun Xu

Int J Oncol. 2018 Jul; 53(1): 148–158. Published online 2018 May 7. doi: 10.3892/ijo.2018.4396

PMCID:: PMC5958727

Article PDF–1.5M

Select item 502962519.

Meta-analysis of transcriptome data identifies a novel 5-gene pancreatic adenocarcinoma classifier

Manoj K. Bhasin, Kenneth Ndebele, Octavian Bucur, Eric U. Yee, Hasan H. Otu, Jessica Plati, Andrea Bullock, Xuesong Gu, Eduardo Castan, Peng Zhang, Robert Najarian, Maria S. Muraru, Rebecca Miksad, Roya Khosravi-Far, Towia A. Libermann

Oncotarget. 2016 Apr 26; 7(17): 23263–23281. Published online 2016 Mar 16. doi: 10.18632/oncotarget.8139

PMCID:: PMC5029625

Article PDF–1.6M

Select item 431778420.

Methylation-induced downregulation of TFPI-2 causes TMPRSS4 overexpression and contributes to oncogenesis in a subset of non-small-cell lung carcinoma

Junko Hamamoto, Kenzo Soejima, Katsuhiko Naoki, Hiroyuki Yasuda, Yuichiro Hayashi, Satoshi Yoda, Sohei Nakayama, Ryosuke Satomi, Hideki Terai, Shinnosuke Ikemura, Takashi Sato, Daisuke Arai, Kota Ishioka, Keiko Ohgino, Tomoko Betsuyaku

Cancer Sci. 2015 Jan; 106(1): 34–42. Published online 2014 Dec 8. doi: 10.1111/cas.12569