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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 82896902.

L-type channel inactivation balances the increased peak calcium current due to absence of Rad in cardiomyocytes

Brooke M. Ahern, Andrea Sebastian, Bryana M. Levitan, Jensen Goh, Douglas A. Andres, Jonathan Satin

J Gen Physiol. 2021 Sep 6; 153(9): e202012854. Published online 2021 Jul 16. doi: 10.1085/jgp.202012854

PMCID:: PMC8289690

Article PDF–5.8M

Select item 68867233.

Rad GTPase is essential for the regulation of bone density and bone marrow adipose tissue in mice

Catherine N. Withers, Drew M. Brown, Innocent Byiringiro, Matthew R. Allen, Keith W. Condon, Jonathan Satin, Douglas A. Andres

Bone. Author manuscript; available in PMC 2019 Dec 2.

Published in final edited form as: Bone. 2017 Oct; 103: 270–280. Published online 2017 Jul 18. doi: 10.1016/j.bone.2017.07.018

PMCID:: PMC6886723

Article PDF–1.6M

Select item 66354394.

Myocardial-restricted ablation of the GTPase RAD results in a pro-adaptive heart response in mice

Brooke M. Ahern, Bryana M. Levitan, Sudhakar Veeranki, Mihir Shah, Nemat Ali, Andrea Sebastian, Wen Su, Ming C. Gong, Jiayang Li, Julian E. Stelzer, Douglas A. Andres, Jonathan Satin

J Biol Chem. 2019 Jul 12; 294(28): 10913–10927. Published online 2019 May 30. doi: 10.1074/jbc.RA119.008782

PMCID:: PMC6635439

Article PDF–4.0M

Select item 51432075.

Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart

Bryana M. Levitan, Janet R. Manning, Catherine N. Withers, Jeffrey D. Smith, Robin M. Shaw, Douglas A. Andres, Vincent L. Sorrell, Jonathan Satin

J Cardiovasc Transl Res. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: J Cardiovasc Transl Res. 2016 Dec; 9(5-6): 432–444. Published online 2016 Oct 31. doi: 10.1007/s12265-016-9716-y

PMCID:: PMC5143207

Article PDF–1.3M

Select item 46315376.

Loss of Rad-GTPase produces a novel adaptive cardiac phenotype resistant to systolic decline with aging

Janet R. Manning, Catherine N. Withers, Bryana Levitan, Jeffrey D. Smith, Douglas A. Andres, Jonathan Satin

Am J Physiol Heart Circ Physiol. 2015 Oct; 309(8): H1336–H1345. Published online 2015 Sep 14. doi: 10.1152/ajpheart.00389.2015

PMCID:: PMC4631537

Article

Select item 38867777.

Rad GTPase Deletion Increases L‐type Calcium Channel Current Leading to Increased Cardiac Contraction

Janet R. Manning, Guo Yin, Catherine N. Kaminski, Janos Magyar, Han‐Zhong Feng, John Penn, Gail Sievert, Katherine Thompson, J.‐P. Jin, Douglas A. Andres, Jonathan Satin

J Am Heart Assoc. 2013 Dec; 2(6): e000459. Published online 2013 Dec 19. doi: 10.1161/JAHA.113.000459

PMCID:: PMC3886777

Article PDF–2.0M

Select item 14501978.

Overexpression of Rad in muscle worsens diet-induced insulin resistance and glucose intolerance and lowers plasma triglyceride level

Jacob Ilany, Philip J. Bilan, Sonia Kapur, James S. Caldwell, Mary-Elizabeth Patti, Andre Marette, C. Ronald Kahn

Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12): 4481–4486. Published online 2006 Mar 14. doi: 10.1073/pnas.0511246103

PMCID:: PMC1450197

Article PDF–1.1M

Select item 42037539.

RGK protein-mediated impairment of slow depolarization- dependent Ca²⁺ entry into developing myotubes

Christin F Romberg, Donald Beqollari, Ulises Meza, Roger A Bannister

Channels (Austin) 2014 May 1; 8(3): 243–248. Published online 2014 Jan 29. doi: 10.4161/chan.27686

PMCID:: PMC4203753

Article PDF–491K

Select item 448502410.

Rem uncouples excitation–contraction coupling in adult skeletal muscle fibers

Donald Beqollari, Christin F. Romberg, Dilyana Filipova, Ulises Meza, Symeon Papadopoulos, Roger A. Bannister

J Gen Physiol. 2015 Jul; 146(1): 97–108. doi: 10.1085/jgp.201411314

PMCID:: PMC4485024

Article PDF–1.9M

Select item 365753711.

Rad GTPase inhibits cardiac fibrosis through connective tissue growth factor

Ji Zhang, Lin Chang, Chunlei Chen, Meiling Zhang, Yan Luo, Milton Hamblin, Luis Villacorta, Jing-Wei Xiong, Y. Eugene Chen, Jifeng Zhang, Xiaojun Zhu

Cardiovasc Res. 2011 Jul 1; 91(1): 90–98. Published online 2011 Mar 7. doi: 10.1093/cvr/cvr068

PMCID:: PMC3657537

Article

Select item 28361512.

Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases

Brian S. Finlin, Shawn M. Crump, Jonathan Satin, Douglas A. Andres

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14469–14474. Published online 2003 Nov 17. doi: 10.1073/pnas.2437756100

PMCID:: PMC283615

Article PDF–454K

Select item 420736213.

Rad GTPase Deficiency Leads to Cardiac Hypertrophy

Lin Chang, Jifeng Zhang, Yu-Hua Tseng, Chang-Qing Xie, Jacob Ilany, Jens C. Brüning, Zhongcui Sun, Xiaojun Zhu, Taixing Cui, Keith A. Youker, Qinglin Yang, Sharlene M. Day, C. Ronald Kahn, Y. Eugene Chen

Circulation. Author manuscript; available in PMC 2014 Oct 23.

Published in final edited form as: Circulation. 2007 Dec 18; 116(25): 2976–2983. Published online 2007 Dec 3. doi: 10.1161/CIRCULATIONAHA.107.707257

PMCID:: PMC4207362

Article PDF–1.3M

Select item 598760614.

Gene expression profiling in the developing secondary palate in the absence of Tbx1 function

Maria Zoupa, Guilherme Machado Xavier, Stephanie Bryan, Ioannis Theologidis, Matthew Arno, Martyn T. Cobourne

BMC Genomics. 2018; 19: 429. Published online 2018 Jun 4. doi: 10.1186/s12864-018-4782-y

PMCID:: PMC5987606

Article PDF–2.6M

Select item 461808615.

The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft

Immunity. Author manuscript; available in PMC 2016 Oct 20.

Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017

PMCID:: PMC4618086

Article PDF–2.2M

Select item 529582116.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Article PDF–3.0M

Select item 396495517.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Article PDF–5.7M

Select item 302253418.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Article PDF–3.8M

Select item 31099219.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Article PDF–3.4M

Select item 31098020.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Article PDF–1.4M

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