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Select item 44111541.

WDR12, a Member of Nucleolar PeBoW-Complex, Is Up-Regulated in Failing Hearts and Causes Deterioration of Cardiac Function

Anne-Mari Moilanen, Jaana Rysä, Leena Kaikkonen, Teemu Karvonen, Erja Mustonen, Raisa Serpi, Zoltán Szabó, Olli Tenhunen, Zsolt Bagyura, Juha Näpänkangas, Pauli Ohukainen, Pasi Tavi, Risto Kerkelä, Margrét Leósdóttir, Björn Wahlstrand, Thomas Hedner, Olle Melander, Heikki Ruskoaho

PLoS One. 2015; 10(4): e0124907. Published online 2015 Apr 27. doi: 10.1371/journal.pone.0124907

PMCID:: PMC4411154

Article PDF–7.4M

Select item 47054062.

The Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase Midasin

Erin M. Romes, Mack Sobhany, Robin E. Stanley

J Biol Chem. 2016 Jan 8; 291(2): 882–893. Published online 2015 Nov 24. doi: 10.1074/jbc.M115.693259

PMCID:: PMC4705406

Article PDF–1.7M

Select item 21714663.

Mammalian WDR12 is a novel member of the Pes1–Bop1 complex and is required for ribosome biogenesis and cell proliferation

Michael Hölzel, Michaela Rohrmoser, Martin Schlee, Thomas Grimm, Thomas Harasim, Anastassia Malamoussi, Anita Gruber-Eber, Elisabeth Kremmer, Wolfgang Hiddemann, Georg W. Bornkamm, Dirk Eick

J Cell Biol. 2005 Aug 1; 170(3): 367–378. doi: 10.1083/jcb.200501141

PMCID:: PMC2171466

Article PDF–2.4M

Select item 18999934.

Interdependence of Pes1, Bop1, and WDR12 Controls Nucleolar Localization and Assembly of the PeBoW Complex Required for Maturation of the 60S Ribosomal Subunit

Michaela Rohrmoser, Michael Hölzel, Thomas Grimm, Anastassia Malamoussi, Thomas Harasim, Mathias Orban, Iris Pfisterer, Anita Gruber-Eber, Elisabeth Kremmer, Dirk Eick

Mol Cell Biol. 2007 May; 27(10): 3682–3694. Published online 2007 Mar 12. doi: 10.1128/MCB.00172-07

PMCID:: PMC1899993

Article PDF–1.5M

Select item 14740605.

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex

Thomas Grimm, Michael Hölzel, Michaela Rohrmoser, Thomas Harasim, Anastassia Malamoussi, Anita Gruber-Eber, Elisabeth Kremmer, Dirk Eick

Nucleic Acids Res. 2006; 34(10): 3030–3043. Published online 2006 May 31. doi: 10.1093/nar/gkl378

PMCID:: PMC1474060

Article PDF–984K

Select item 24310416.

Isolation and Characterization of a Novel H1.2 Complex That Acts as a Repressor of p53-mediated Transcription

Kyunghwan Kim, Jongkyu Choi, Kyu Heo, Hyunjung Kim, David Levens, Kimitoshi Kohno, Edward M. Johnson, Hugh W. Brock, Woojin An

J Biol Chem. 2008 Apr 4; 283(14): 9113–9126. doi: 10.1074/jbc.M708205200

PMCID:: PMC2431041

Article PDF–757K

Select item 26810117.

Genome-wide association of early-onset myocardial infarction with common single nucleotide polymorphisms, common copy number variants, and rare copy number variants

Myocardial Infarction Genetics Consortium

Nat Genet. Author manuscript; available in PMC 2009 Sep 1.

Published in final edited form as: Nat Genet. 2009 Mar; 41(3): 334–341. Published online 2009 Feb 8. doi: 10.1038/ng.327

Correction in:: volume 41 on page 762

PMCID:: PMC2681011

Article PDF–630K

Select item 29653518.

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

Samuli Ripatti, Emmi Tikkanen, Marju Orho-Melander, Aki S Havulinna, Kaisa Silander, Amitabh Sharma, Candace Guiducci, Markus Perola, Antti Jula, Juha Sinisalo, Marja-Liisa Lokki, Markku S Nieminen, Olle Melander, Veikko Salomaa, Leena Peltonen, Sekar Kathiresan

Lancet. 2010 Oct 23; 376(9750): 1393–1400. doi: 10.1016/S0140-6736(10)61267-6

PMCID:: PMC2965351

Article

Select item 46830569.

Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7)

Xiaodan Ding, Wei Jiang, Peipei Zhou, Lulu Liu, Xiaoling Wan, Xiujie Yuan, Xizi Wang, Miao Chen, Jun Chen, Jing Yang, Chao Kong, Bin Li, Chao Peng, Catherine C. L. Wong, Fajian Hou, Yan Zhang

PLoS One. 2015; 10(12): e0145023. Published online 2015 Dec 17. doi: 10.1371/journal.pone.0145023

PMCID:: PMC4683056

Article PDF–4.1M

Select item 311926110.

Large-scale association analyses identifies 13 new susceptibility loci for coronary artery disease

Heribert Schunkert, Inke R. König, Sekar Kathiresan, Muredach P. Reilly, Themistocles L. Assimes, Hilma Holm, Michael Preuss, Alexandre F. R. Stewart, Maja Barbalic, Christian Gieger, Devin Absher, Zouhair Aherrahrou, Hooman Allayee, David Altshuler, Sonia S. Anand, Karl Andersen, Jeffrey L. Anderson, Diego Ardissino, Stephen G. Ball, Anthony J. Balmforth, Timothy A. Barnes, Diane M. Becker, Lewis C. Becker, Klaus Berger, Joshua C. Bis, S. Matthijs Boekholdt, Eric Boerwinkle, Peter S. Braund, Morris J. Brown, Mary Susan Burnett, Ian Buysschaert, Cardiogenics, John F. Carlquist, Li Chen, Sven Cichon, Veryan Codd, Robert W. Davies, George Dedoussis, Abbas Dehghan, Serkalem Demissie, Joseph M. Devaney, Ron Do, Angela Doering, Sandra Eifert, Nour Eddine El Mokhtari, Stephen G. Ellis, Roberto Elosua, James C. Engert, Stephen E. Epstein, Ulf de Faire, Marcus Fischer, Aaron R. Folsom, Jennifer Freyer, Bruna Gigante, Domenico Girelli, Solveig Gretarsdottir, Vilmundur Gudnason, Jeffrey R. Gulcher, Eran Halperin, Naomi Hammond, Stanley L. Hazen, Albert Hofman, Benjamin D. Horne, Thomas Illig, Carlos Iribarren, Gregory T. Jones, J.Wouter Jukema, Michael A. Kaiser, Lee M. Kaplan, John J.P. Kastelein, Kay-Tee Khaw, Joshua W. Knowles, Genovefa Kolovou, Augustine Kong, Reijo Laaksonen, Diether Lambrechts, Karin Leander, Guillaume Lettre, Mingyao Li, Wolfgang Lieb, Patrick Linsel-Nitschke, Christina Loley, Andrew J. Lotery, Pier M. Mannucci, Seraya Maouche, Nicola Martinelli, Pascal P. McKeown, Christa Meisinger, Thomas Meitinger, Olle Melander, Pier Angelica Merlini, Vincent Mooser, Thomas Morgan, Thomas W. Mühleisen, Joseph B. Muhlestein, Thomas Münzel, Kiran Musunuru, Janja Nahrstaedt, Christopher P. Nelson, Markus M. Nöthen, Oliviero Olivieri, Riyaz S. Patel, Chris C. Patterson, Annette Peters, Flora Peyvandi, Liming Qu, Arshed A. Quyyumi, Daniel J. Rader, Loukianos S. Rallidis, Catherine Rice, Frits R. Rosendaal, Diana Rubin, Veikko Salomaa, M. Lourdes Sampietro, Manj S. Sandhu, Eric Schadt, Arne Schäfer, Arne Schillert, Stefan Schreiber, Jürgen Schrezenmeir, Stephen M. Schwartz, David S. Siscovick, Mohan Sivananthan, Suthesh Sivapalaratnam, Albert Smith, Tamara B. Smith, Jaapjan D. Snoep, Nicole Soranzo, John A. Spertus, Klaus Stark, Kathy Stirrups, Monika Stoll, W. H. Wilson Tang, Stephanie Tennstedt, Gudmundur Thorgeirsson, Gudmar Thorleifsson, Maciej Tomaszewski, Andre G. Uitterlinden, Andre M. van Rij, Benjamin F. Voight, Nick J. Wareham, George A. Wells, H.-Erich Wichmann, Philipp S. Wild, Christina Willenborg, Jaqueline C. M. Witteman, Benjamin J. Wright, Shu Ye, Tanja Zeller, Andreas Ziegler, Francois Cambien, Alison H. Goodall, L. Adrienne Cupples, Thomas Quertermous, Winfried März, Christian Hengstenberg, Stefan Blankenberg, Willem H. Ouwehand, Alistair S. Hall, Panos Deloukas, John R. Thompson, Kari Stefansson, Robert Roberts, Unnur Thorsteinsdottir, Christopher J. O’Donnell, Ruth McPherson, Jeanette Erdmann, Nilesh J. Samani

Nat Genet. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Nat Genet. 2011 Mar 6; 43(4): 333–338. Published online 2011 Mar 6. doi: 10.1038/ng.784

PMCID:: PMC3119261

Article PDF–405K

Select item 411210211.

Shared genetic susceptibility to ischemic stroke and coronary artery disease – a genome-wide analysis of common variants

Martin Dichgans, Rainer Malik, Inke R. König, Jonathan Rosand, Robert Clarke, Solveig Gretarsdottir, Gudmar Thorleifsson, Braxton D. Mitchell, Themistocles L. Assimes, Christopher Levi, Christopher J. O′Donnell, Myriam Fornage, Unnur Thorsteinsdottir, Bruce M. Psaty, Christian Hengstenberg, Sudha Seshadri, Jeanette Erdmann, Joshua C. Bis, Annette Peters, Giorgio B. Boncoraglio, Winfried März, James F. Meschia, Sekar Kathiresan, M. Arfan Ikram, Ruth McPherson, Kari Stefansson, Cathie Sudlow, Muredach P. Reilly, John R. Thompson, Pankaj Sharma, Jemma C. Hopewell, John C. Chambers, Hugh Watkins, Peter M. Rothwell, Robert Roberts, the METASTROKE Consortium, the CARDIoGRAM consortium, the C4D consortium, the International Stroke Genetics Consortium, Hugh S. Markus, Nilesh J. Samani, Martin Farrall, Heribert Schunkert

Stroke. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Stroke. 2014 Jan; 45(1): 24–36. Published online 2013 Nov 21. doi: 10.1161/STROKEAHA.113.002707

PMCID:: PMC4112102

Article PDF–979K

Select item 13361712.

Functional Proteomic Analysis of Human Nucleolus

Alexander Scherl, Yohann Couté, Catherine Déon, Aleth Callé, Karine Kindbeiter, Jean-Charles Sanchez, Anna Greco, Denis Hochstrasser, Jean-Jacques Diaz

Mol Biol Cell. 2002 Nov; 13(11): 4100–4109. doi: 10.1091/mbc.E02-05-0271

PMCID:: PMC133617

Article PDF–369K

Select item 342832413.

Targeted Ubiquitination and Degradation of G-Protein-Coupled Receptor Kinase 5 by the DDB1-CUL4 Ubiquitin Ligase Complex

Ziyan Wu, Yuejun Chen, Tong Yang, Qinqin Gao, Man Yuan, Lan Ma

PLoS One. 2012; 7(8): e43997. Published online 2012 Aug 27. doi: 10.1371/journal.pone.0043997

PMCID:: PMC3428324

Article PDF–2.0M

Select item 846595314.

Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus

Xiaoqin Zheng, Zeyu Sun, Liang Yu, Danrong Shi, Miaojin Zhu, Hangping Yao, Lanjuan Li

Pathogens. 2021 Sep; 10(9): 1155. Published online 2021 Sep 8. doi: 10.3390/pathogens10091155

PMCID:: PMC8465953

Article PDF–1.7M

Select item 328162815.

Cytoplasmic Metadherin (MTDH) Provides Survival Advantage under Conditions of Stress by Acting as RNA-binding Protein

Xiangbing Meng, Danlin Zhu, Shujie Yang, Xinjun Wang, Zhi Xiong, Yuping Zhang, Pavla Brachova, Kimberly K. Leslie

J Biol Chem. 2012 Feb 10; 287(7): 4485–4491. Published online 2011 Dec 23. doi: 10.1074/jbc.C111.291518

PMCID:: PMC3281628

Article PDF–2.0M

Select item 458732616.

BioID-based Identification of Skp Cullin F-box (SCF)^β-TrCP1/2 E3 Ligase Substrates

Etienne Coyaud, Monika Mis, Estelle M. N. Laurent, Wade H. Dunham, Amber L. Couzens, Melanie Robitaille, Anne-Claude Gingras, Stephane Angers, Brian Raught

Mol Cell Proteomics. 2015 Jul; 14(7): 1781–1795. Published online 2015 Apr 21. doi: 10.1074/mcp.M114.045658