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Items: 1 to 20 of 162

1.
VPS35 down regulation alters degradation pathways in neuronal cells
Alessia Filippone, Jian-Guo Li, Domenico Praticò
J Alzheimers Dis. Author manuscript; available in PMC 2022 Jun 14.
Published in final edited form as: J Alzheimers Dis. 2021; 84(3): 1079–1089. doi: 10.3233/JAD-210701
PMCID:
PMC9195474
ArticlePDF–1.9M
2.
ITRAQ-based quantitative proteomic analysis reveals that VPS35 promotes the expression of MCM2-7 genes in HeLa cells
Xian Hong, Tao Wang, Juan Du, Yu Hong, Cai-Ping Yang, Wei Xiao, Yang Li, Ming Wang, He Sun, Zhi-Hui Deng
Sci Rep. 2022; 12: 9700. Published online 2022 Jun 11. doi: 10.1038/s41598-022-13934-3
PMCID:
PMC9188599
ArticlePDF–1.9M
3.
Parkinson’s disease–associated VPS35 mutant reduces mitochondrial membrane potential and impairs PINK1/Parkin-mediated mitophagy
Kai Yu Ma, Michiel R. Fokkens, Fulvio Reggiori, Muriel Mari, Dineke S. Verbeek
Transl Neurodegener. 2021; 10: 19. Published online 2021 Jun 15. doi: 10.1186/s40035-021-00243-4
PMCID:
PMC8204421
ArticlePDF–4.4M
4.
Parkinson’s Disease Causative Mutation in Vps35 Disturbs Tetherin Trafficking to Cell Surfaces and Facilitates Virus Spread
Yingzhuo Ding, Yan Li, Gaurav Chhetri, Xiaoxin Peng, Jing Wu, Zejian Wang, Bo Zhao, Wenjuan Zhao, Xueyi Li
Cells. 2021 Apr; 10(4): 746. Published online 2021 Mar 28. doi: 10.3390/cells10040746
PMCID:
PMC8066283
ArticlePDF–9.0M
5.
Mitochondrial and Clearance Impairment in p.D620N VPS35 Patient‐Derived Neurons
Zoé Hanss, Simone B. Larsen, Paul Antony, Pauline Mencke, François Massart, Javier Jarazo, Jens C. Schwamborn, Peter A. Barbuti, George D. Mellick, Rejko Krüger
Mov Disord. 2021 Mar; 36(3): 704–715. Published online 2020 Nov 3. doi: 10.1002/mds.28365
PMCID:
PMC8048506
ArticlePDF–6.5M
6.
Endosomal dysfunction in iPSC-derived neural cells from Parkinson’s disease patients with VPS35 D620N
Keiko Bono, Chikako Hara-Miyauchi, Shunsuke Sumi, Hisayoshi Oka, Yasuyuki Iguchi, Hirotaka James Okano
Mol Brain. 2020; 13: 137. Published online 2020 Oct 8. doi: 10.1186/s13041-020-00675-5
PMCID:
PMC7542911
ArticlePDF–1.5M
7.
Enhanced hyaluronan signaling and autophagy dysfunction by VPS35 D620N
Abir A. Rahman, Alejandro Soto-Avellaneda, Hyun Yong Jin, Iva Stojkovska, Nathan K. Lai, Joshua E. Albright, Abby R. Webb, Emily Oe, Jacob P. Valarde, Alexandra E. Oxford, Paige E. Urquhart, Brandon Wagner, Connor Brown, Isabella Amado, Peyton Vasquez, Nicholas Lehning, Veselin Grozdanov, Xinzhu Pu, Karin M. Danzer, Brad E. Morrison
Neuroscience. Author manuscript; available in PMC 2021 Aug 10.
Published in final edited form as: Neuroscience. 2020 Aug 10; 441: 33–45. Published online 2020 Jun 13. doi: 10.1016/j.neuroscience.2020.06.009
PMCID:
PMC7390708
ArticlePDF–1.3M
8.
Where no Ras has gone before: VPS35 steers N-Ras through the cytosol
Mo Zhou, Mark R. Philips
Small GTPases. 2019 Jan; 10(1): 20–25. Published online 2017 Jan 27. doi: 10.1080/21541248.2016.1263380
PMCID:
PMC6343534
ArticlePDF–605K
9.
Parkinson’s Disease-Associated Pathogenic VPS35 Mutation Causes Complex I Deficits
Leping Zhou, Wenzhang Wang, Charles Hoppel, Jun Liu, Xiongwei Zhu
Biochim Biophys Acta. Author manuscript; available in PMC 2018 Nov 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Nov; 1863(11): 2791–2795. Published online 2017 Jul 29. doi: 10.1016/j.bbadis.2017.07.032
PMCID:
PMC5659972
ArticlePDF–1.4M
10.
Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development
Zhen-Dong Xiao, Leng Han, Hyemin Lee, Li Zhuang, Yilei Zhang, Joelle Baddour, Deepak Nagrath, Christopher G. Wood, Jian Gu, Xifeng Wu, Han Liang, Boyi Gan
Nat Commun. 2017; 8: 783. Published online 2017 Oct 4. doi: 10.1038/s41467-017-00902-z
PMCID:
PMC5627275
ArticlePDF–1.1M
11.
VPS35, the Retromer Complex and Parkinson’s Disease
Erin T. Williams, Xi Chen, Darren J. Moore
J Parkinsons Dis. 2017; 7(2): 219–233. Prepublished online 2017 Feb 8. Published online 2017 May 16. doi: 10.3233/JPD-161020
PMCID:
PMC5438477
ArticlePDF–433K
12.
Screening for VPS35 mutations in Parkinson's disease
Una-Marie Sheerin, Gavin Charlesworth, Jose Bras, Rita Guerreiro, Kailash Bhatia, Thomas Foltynie, Patricia Limousin, Laura Silveira-Moriyama, Andrew Lees, Nicholas Wood
Neurobiol Aging. 2012 Apr; 33(4): 838.e1–838.e5. doi: 10.1016/j.neurobiolaging.2011.10.032
PMCID:
PMC3629567
Article
13.
Pathogenic Mutation in VPS35 Impairs Its Protection against MPP+ Cytotoxicity
Fangfang Bi, Fang Li, Cao Huang, Hongxia Zhou
Int J Biol Sci. 2013; 9(2): 149–155. Published online 2013 Jan 26. doi: 10.7150/ijbs.5617
PMCID:
PMC3572397
ArticlePDF–1.0M
14.
A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants
Manu Sharma, John P A Ioannidis, Jan O Aasly, Grazia Annesi, Alexis Brice, Lars Bertram, Maria Bozi, Maria Barcikowska, David Crosiers, Carl E Clarke, Maurizio F Facheris, Matthew Farrer, Gaetan Garraux, Suzana Gispert, Georg Auburger, Carles Vilariño-Güell, Georgios M Hadjigeorgiou, Andrew A Hicks, Nobutaka Hattori, Beom S Jeon, Zygmunt Jamrozik, Anna Krygowska-Wajs, Suzanne Lesage, Christina M Lill, Juei-Jueng Lin, Timothy Lynch, Peter Lichtner, Anthony E Lang, Cecile Libioulle, Miho Murata, Vincent Mok, Barbara Jasinska-Myga, George D Mellick, Karen E Morrison, Thomas Meitnger, Alexander Zimprich, Grzegorz Opala, Peter P Pramstaller, Irene Pichler, Sung Sup Park, Aldo Quattrone, Ekaterina Rogaeva, Owen A. Ross, Leonidas Stefanis, Joanne D Stockton, Wataru Satake, Peter A Silburn, Tim M Strom, Jessie Theuns, Eng- King Tan, Tatsushi Toda, Hiroyuki Tomiyama, Ryan J Uitti, Christine Van Broeckhoven, Karin Wirdefeldt, Zbigniew Wszolek, Georgia Xiromerisiou, Harumi S Yomono, Kuo-Chu Yueh, Yi Zhao, Thomas Gasser, Demetrius Maraganore, Rejko Krüger, on behalf of GEOPD consortium
J Med Genet. 2012 Nov; 49(11): 721–726. doi: 10.1136/jmedgenet-2012-101155
Correction in:
J Med Genet. 2013 Mar; 50(3): 202.
PMCID:
PMC3488700
ArticlePDF–219K
15.
Inhibition of Retromer Activity by Herpesvirus Saimiri Tip Leads to CD4 Downregulation and Efficient T Cell Transformation
Dior Kingston, Heesoon Chang, Armin Ensser, Hye-Ra Lee, Jongsoo Lee, Sun-Hwa Lee, Jae Ung Jung, Nam-Hyuk Cho
J Virol. 2011 Oct; 85(20): 10627–10638. doi: 10.1128/JVI.00757-11
PMCID:
PMC3187508
ArticlePDF–2.4M
16.
A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
Alexander Zimprich, Anna Benet-Pagès, Walter Struhal, Elisabeth Graf, Sebastian H. Eck, Marc N. Offman, Dietrich Haubenberger, Sabine Spielberger, Eva C. Schulte, Peter Lichtner, Shaila C. Rossle, Norman Klopp, Elisabeth Wolf, Klaus Seppi, Walter Pirker, Stefan Presslauer, Brit Mollenhauer, Regina Katzenschlager, Thomas Foki, Christoph Hotzy, Eva Reinthaler, Ashot Harutyunyan, Robert Kralovics, Annette Peters, Fritz Zimprich, Thomas Brücke, Werner Poewe, Eduard Auff, Claudia Trenkwalder, Burkhard Rost, Gerhard Ransmayr, Juliane Winkelmann, Thomas Meitinger, Tim M. Strom
Am J Hum Genet. 2011 Jul 15; 89(1): 168–175. doi: 10.1016/j.ajhg.2011.06.008
PMCID:
PMC3135812
ArticlePDF–308K
17.
VPS35 Mutations in Parkinson Disease
Carles Vilariño-Güell, Christian Wider, Owen A. Ross, Justus C. Dachsel, Jennifer M. Kachergus, Sarah J. Lincoln, Alexandra I. Soto-Ortolaza, Stephanie A. Cobb, Greggory J. Wilhoite, Justin A. Bacon, Bahareh Behrouz, Heather L. Melrose, Emna Hentati, Andreas Puschmann, Daniel M. Evans, Elizabeth Conibear, Wyeth W. Wasserman, Jan O. Aasly, Pierre R. Burkhard, Ruth Djaldetti, Joseph Ghika, Faycal Hentati, Anna Krygowska-Wajs, Tim Lynch, Eldad Melamed, Alex Rajput, Ali H. Rajput, Alessandra Solida, Ruey-Meei Wu, Ryan J. Uitti, Zbigniew K. Wszolek, François Vingerhoets, Matthew J. Farrer
Am J Hum Genet. 2011 Jul 15; 89(1): 162–167. doi: 10.1016/j.ajhg.2011.06.001
Correction in:
Am J Hum Genet. 2011 Aug 12; 89(2): 347.
PMCID:
PMC3135796
ArticlePDF–580K
18.
The impact of VPS35 D620N mutation on alternative autophagy and its reversal by estrogen in Parkinson's disease
Tomotaka Shiraishi, Keiko Bono, Hiromi Hiraki, Yoko Manome, Hisayoshi Oka, Yasuyuki Iguchi, Hirotaka James Okano
Cell Mol Life Sci. 2024; 81(1): 103. Published online 2024 Feb 27. doi: 10.1007/s00018-024-05123-4
PMCID:
PMC10896810
ArticlePDF–3.8M
19.
VPS35 and retromer dysfunction in Parkinson's disease
Jordan Rowlands, Darren J. Moore
Philos Trans R Soc Lond B Biol Sci. April 8, 2024; 379(1899): 20220384. Published online February 19, 2024. doi: 10.1098/rstb.2022.0384
PMCID:
PMC10874700
ArticlePDF–578K
20.
VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer
Junxian Yu, Haoran Feng, Qingqing Sang, Fangyuan Li, Mengdi Chen, Beiqin Yu, Zhuoqing Xu, Tao Pan, Xiongyan Wu, Junyi Hou, Zhenggang Zhu, Chao Yan, Liping Su, Jianfang Li, Bingya Liu
eBioMedicine. 2023 Mar; 89: 104451. Published online 2023 Feb 2. doi: 10.1016/j.ebiom.2023.104451
PMCID:
PMC9931929
ArticlePDF–5.6M

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