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Select item 87452361.

RNA Exosome Component EXOSC4 Amplified in Multiple Cancer Types Is Required for the Cancer Cell Survival

Kenzui Taniue, Tanzina Tanu, Yuki Shimoura, Shuhei Mitsutomi, Han Han, Rika Kakisaka, Yusuke Ono, Nobue Tamamura, Kenji Takahashi, Youichiro Wada, Yusuke Mizukami, Nobuyoshi Akimitsu

Int J Mol Sci. 2022 Jan; 23(1): 496. Published online 2022 Jan 2. doi: 10.3390/ijms23010496

PMCID:: PMC8745236

Article PDF–6.0M

Select item 15819852.

Sequence-specific RNA binding mediated by the RNase PH domain of components of the exosome

John R. Anderson, Devi Mukherjee, Karthika Muthukumaraswamy, Karen C.M. Moraes, Carol J. Wilusz, Jeffrey Wilusz

RNA. 2006 Oct; 12(10): 1810–1816. doi: 10.1261/rna.144606

PMCID:: PMC1581985

Article PDF–435K

Select item 72694413.

Osteopetrosis-Associated Transmembrane Protein 1 Recruits RNA Exosome To Restrict Hepatitis B Virus Replication

Chunqiang Ma, Wei Xu, Qingyu Yang, Weiyong Liu, Qi Xiang, Junbo Chen, Qi Zhang, Yingle Liu, Kailang Wu, Jianguo Wu

J Virol. 2020 Jun; 94(11): e01800-19. Prepublished online 2020 Mar 18. Published online 2020 May 18. doi: 10.1128/JVI.01800-19

PMCID:: PMC7269441

Article PDF–4.7M

Select item 30010754.

A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination

Sérgio F. de Almeida, Ana García-Sacristán, Noélia Custódio, Maria Carmo-Fonseca

Nucleic Acids Res. 2010 Dec; 38(22): 8015–8026. Published online 2010 Aug 10. doi: 10.1093/nar/gkq703

PMCID:: PMC3001075

Article PDF–5.2M

Select item 838435.

Autoantibodies directed to novel components of the PM/Scl complex, the human exosome

Rick Brouwer, Wilma TM Vree Egberts, Gerald JD Hengstman, Reinout Raijmakers, Baziel GM van Engelen, Hans Peter Seelig, Manfred Renz, Rudolf Mierau, Ekkehard Genth, Ger JM Pruijn, Walther J van Venrooij

Arthritis Res. 2002; 4(2): 134–138. Published online 2001 Nov 12. doi: 10.1186/ar389

PMCID:: PMC83843

Article PDF–56K

Select item 28676916.

Addition of poly(A) and poly(A)-rich tails during RNA degradation in the cytoplasm of human cells

Shimyn Slomovic, Ella Fremder, Raymond H. G. Staals, Ger J. M. Pruijn, Gadi Schuster

Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16): 7407–7412. Published online 2010 Apr 5. doi: 10.1073/pnas.0910621107

PMCID:: PMC2867691

Article PDF–906K

Select item 95859117.

Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication

Tobias Moll, Valerie Odon, Calum Harvey, Mark O Collins, Andrew Peden, John Franklin, Emily Graves, Jack NG Marshall, Cleide dos Santos Souza, Sai Zhang, Lydia Castelli, Guillaume Hautbergue, Mimoun Azzouz, David Gordon, Nevan Krogan, Laura Ferraiuolo, Michael P Snyder, Pamela J Shaw, Jan Rehwinkel, Johnathan Cooper-Knock

Life Sci Alliance. 2023 Jan; 6(1): e202201449. Published online 2022 Oct 14. doi: 10.26508/lsa.202201449

PMCID:: PMC9585911

Article PDF–1.7M

Select item 18949348.

Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways

Erwin L. van Dijk, Geurt Schilders, Ger J.M. Pruijn

RNA. 2007 Jul; 13(7): 1027–1035. doi: 10.1261/rna.575107

PMCID:: PMC1894934

Article PDF–719K

Select item 31657249.

DDX60, a DEXD/H Box Helicase, Is a Novel Antiviral Factor Promoting RIG-I-Like Receptor-Mediated Signaling

Moeko Miyashita, Hiroyuki Oshiumi, Misako Matsumoto, Tsukasa Seya

Mol Cell Biol. 2011 Sep; 31(18): 3802–3819. doi: 10.1128/MCB.01368-10

PMCID:: PMC3165724

Article PDF–6.3M

Select item 31694710.

The yeast exosome and human PM–Scl are related complexes of 3′ → 5′ exonucleases

Christine Allmang, Elisabeth Petfalski, Alexandre Podtelejnikov, Matthias Mann, David Tollervey, Philip Mitchell

Genes Dev. 1999 Aug 15; 13(16): 2148–2158. doi: 10.1101/gad.13.16.2148

PMCID:: PMC316947

Article PDF–1.1M

Select item 431024811.

Structure of an Rrp6-RNA exosome complex bound to polyA RNA

Elizabeth V. Wasmuth, Kurt Januszyk, Christopher D. Lima

Nature. Author manuscript; available in PMC 2015 Jan 29.

Published in final edited form as: Nature. 2014 Jul 24; 511(7510): 435–439. Published online 2014 Jul 6. doi: 10.1038/nature13406

PMCID:: PMC4310248

Article PDF–5.2M

Select item 306511412.

The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates

Uttiya Basu, Fei-Long Meng, Celia Keim, Veronika Grinstein, Evangelos Pefanis, Jennifer Eccleston, Tingting Zhang, Darienne Myers, Duane R. Wesemann, Kurt Januszyk, Richard I. Gregory, Haiteng Deng, Christopher D. Lima, Frederick W. Alt

Cell. Author manuscript; available in PMC 2011 Aug 4.

Published in final edited form as: Cell. 2011 Feb 4; 144(3): 353–363. Published online 2011 Jan 20. doi: 10.1016/j.cell.2011.01.001

PMCID:: PMC3065114

Article PDF–2.9M

Select item 494267513.

Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex

Eva Kowalinski, Alexander Kögel, Judith Ebert, Peter Reichelt, Elisabeth Stegmann, Bianca Habermann, Elena Conti

Mol Cell. 2016 Jul 7; 63(1): 125–134. doi: 10.1016/j.molcel.2016.05.028

PMCID:: PMC4942675

Article

Select item 560372914.

Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase

Sebastian Falk, Fabien Bonneau, Judith Ebert, Alexander Kögel, Elena Conti

Cell Rep. 2017 Sep 5; 20(10): 2279–2286. Published online 2017 Sep 5. doi: 10.1016/j.celrep.2017.08.033

PMCID:: PMC5603729

Article

Select item 215101415.

Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5′ to 3′ and 3′ to 5′

Thomas E. Mullen, William F. Marzluff

Genes Dev. 2008 Jan 1; 22(1): 50–65. doi: 10.1101/gad.1622708

PMCID:: PMC2151014

Article PDF–1.2M

Select item 291027216.

Dis3-like 1: a novel exoribonuclease associated with the human exosome

Raymond H J Staals, Alfred W Bronkhorst, Geurt Schilders, Shimyn Slomovic, Gadi Schuster, Albert J R Heck, Reinout Raijmakers, Ger J M Pruijn

EMBO J. 2010 Jul 21; 29(14): 2358–2367. Published online 2010 Jun 8. doi: 10.1038/emboj.2010.122

PMCID:: PMC2910272

Article PDF–914K

Select item 291027117.

The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L

Rafal Tomecki, Maiken S Kristiansen, Søren Lykke-Andersen, Aleksander Chlebowski, Katja M Larsen, Roman J Szczesny, Karolina Drazkowska, Agnieszka Pastula, Jens S Andersen, Piotr P Stepien, Andrzej Dziembowski, Torben Heick Jensen

EMBO J. 2010 Jul 21; 29(14): 2342–2357. Published online 2010 Jun 8. doi: 10.1038/emboj.2010.121

PMCID:: PMC2910271

Article PDF–2.7M

Select item 576815018.

MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4B^DCAF13 E3 Ligase in Osteosarcoma Cells

Zhi Chen, Wei Zhang, Kaibiao Jiang, Bin Chen, Kun Wang, Lifeng Lao, Canglong Hou, Fei Wang, Caiguo Zhang, Hongxing Shen

Mol Ther Nucleic Acids. 2018 Mar 2; 10: 254–268. Published online 2017 Dec 22. doi: 10.1016/j.omtn.2017.12.010

PMCID:: PMC5768150

Article PDF–2.7M

Select item 352727619.

A Synthetic Interaction Screen Identifies Factors Selectively Required for Proliferation and TERT Transcription in p53-Deficient Human Cancer Cells

Li Xie, Claude Gazin, Sung Mi Park, Lihua J. Zhu, Marie-anne Debily, Ellen L. W. Kittler, Maria L. Zapp, David Lapointe, Stephane Gobeil, Ching-Man Virbasius, Michael R. Green

PLoS Genet. 2012 Dec; 8(12): e1003151. Published online 2012 Dec 20. doi: 10.1371/journal.pgen.1003151