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Items: 1 to 20 of 113

1.
Allosteric modulation of cytochrome P450 enzymes by the NADPH cytochrome P450 reductase FMN-containing domain
Sarah D. Burris-Hiday, Emily E. Scott
J Biol Chem. 2023 Sep; 299(9): 105112. Published online 2023 Jul 28. doi: 10.1016/j.jbc.2023.105112
PMCID:
PMC10481364
ArticlePDF–2.2M
2.
Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism
Francisco Esteves, Cristina M. M. Almeida, Sofia Silva, Inês Saldanha, Philippe Urban, José Rueff, Denis Pompon, Gilles Truan, Michel Kranendonk
Biomolecules. 2023 Jul; 13(7): 1083. Published online 2023 Jul 6. doi: 10.3390/biom13071083
PMCID:
PMC10377444
ArticlePDF–3.2M
3.
In Silico Analysis of PORD Mutations on the 3D Structure of P450 Oxidoreductase
Muhammad Nurhafizuddin, Aziemah Azizi, Long Chiau Ming, Naeem Shafqat
Molecules. 2022 Jul; 27(14): 4646. Published online 2022 Jul 21. doi: 10.3390/molecules27144646
PMCID:
PMC9323898
ArticlePDF–3.1M
4.
POR polymorphisms are associated with 21 hydroxylase deficiency
F. Pecori Giraldi, S. Einaudi, A. Sesta, F. Verna, M. Messina, C. Manieri, E. Menegatti, L. Ghizzoni
J Endocrinol Invest. 2021; 44(10): 2219–2226. Published online 2021 Mar 5. doi: 10.1007/s40618-021-01527-2
PMCID:
PMC8421294
ArticlePDF–628K
5.
Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase
Simon Bo Jensen, Sara Thodberg, Shaheena Parween, Matias E. Moses, Cecilie C. Hansen, Johannes Thomsen, Magnus B. Sletfjerding, Camilla Knudsen, Rita Del Giudice, Philip M. Lund, Patricia R. Castaño, Yanet G. Bustamante, Maria Natalia Rojas Velazquez, Flemming Steen Jørgensen, Amit V. Pandey, Tomas Laursen, Birger Lindberg Møller, Nikos S. Hatzakis
Nat Commun. 2021; 12: 2260. Published online 2021 Apr 15. doi: 10.1038/s41467-021-22562-w
PMCID:
PMC8050233
ArticlePDF–3.2M
6.
Clinical and genetic analysis of cytochrome P450 oxidoreductase (POR) deficiency in a female and the analysis of a novel POR intron mutation causing alternative mRNA splicing: Overall analysis of a female with POR deficiency
Tao Zhang, Zhou Li, Xinling Ren, Bo Huang, Guijin Zhu, Wei Yang, Lei Jin
J Assist Reprod Genet. 2020 Oct; 37(10): 2503–2511. Published online 2020 Jul 28. doi: 10.1007/s10815-020-01899-z
PMCID:
PMC7550433
ArticlePDF–1.0M
7.
Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450
Diana Campelo, Francisco Esteves, Bernardo Brito Palma, Bruno Costa Gomes, José Rueff, Thomas Lautier, Philippe Urban, Gilles Truan, Michel Kranendonk
Int J Mol Sci. 2018 Dec; 19(12): 3914. Published online 2018 Dec 6. doi: 10.3390/ijms19123914
PMCID:
PMC6321550
ArticlePDF–1.8M
8.
Differentiation‐associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic‐metabolizing activity of “luminal” muscle‐invasive bladder cancers
Simon C. Baker, Volker M. Arlt, Radek Indra, Madeleine Joel, Marie Stiborová, Ian Eardley, Niaz Ahmad, Wolfgang Otto, Maximilian Burger, Peter Rubenwolf, David H. Phillips, Jennifer Southgate
Mol Carcinog. 2018 May; 57(5): 606–618. Published online 2018 Feb 1. doi: 10.1002/mc.22784
PMCID:
PMC5900743
ArticlePDF–5.2M
9.
Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro
Duanpen Sandee, Kari Morrissey, Vishal Agrawal, Harrison K. Tam, Melissa A. Kramer, Timothy S. Tracy, Kathleen M. Giacomini, Walter L. Miller
Pharmacogenet Genomics. Author manuscript; available in PMC 2017 Nov 30.
Published in final edited form as: Pharmacogenet Genomics. 2010 Nov; 20(11): 677–686. doi: 10.1097/FPC.0b013e32833f4f9b
PMCID:
PMC5708132
ArticlePDF–1.6M
10.
Orchestrated Domain Movement in Catalysis by Cytochrome P450 Reductase
Samuel L. Freeman, Anne Martel, Emma L. Raven, Gordon C. K. Roberts
Sci Rep. 2017; 7: 9741. Published online 2017 Aug 29. doi: 10.1038/s41598-017-09840-8
PMCID:
PMC5575293
ArticlePDF–3.0M
11.
Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype
Karen M. McCammon, Satya P. Panda, Chuanwu Xia, Jung-Ja P. Kim, Daniela Moutinho, Michel Kranendonk, Richard J. Auchus, Eileen M. Lafer, Debashis Ghosh, Pavel Martasek, Rekha Kar, Bettie Sue Masters, Linda J. Roman
J Biol Chem. 2016 Sep 23; 291(39): 20487–20502. Published online 2016 Aug 5. doi: 10.1074/jbc.M116.716019
PMCID:
PMC5034044
ArticlePDF–1.5M
12.
Correlation of Cytochrome P450 Oxidoreductase Expression with the Expression of 10 Isoforms of Cytochrome P450 in Human Liver
Hai-Feng Zhang, Zhi-Hui Li, Jia-Yu Liu, Ting-Ting Liu, Ping Wang, Yan Fang, Jun Zhou, Ming-Zhu Cui, Na Gao, Xin Tian, Jie Gao, Qiang Wen, Lin-Jing Jia, Hai-Ling Qiao
Drug Metab Dispos. 2016 Aug; 44(8): 1193–1200. Published online 2016 Aug. doi: 10.1124/dmd.116.069849
PMCID:
PMC4986620
ArticlePDF–650K
13.
Electron transfer by human wild-type and A287P mutant P450 oxidoreductase assessed by transient kinetics: functional basis of P450 oxidoreductase deficiency
Yi Jin, Mo Chen, Trevor M. Penning, Walter L. Miller
Biochem J. Author manuscript; available in PMC 2016 May 15.
Published in final edited form as: Biochem J. 2015 May 15; 468(1): 25–31. doi: 10.1042/BJ20141410
PMCID:
PMC4692368
ArticlePDF–1.5M
14.
Genetic variations in NADPH-CYP450 oxidoreductase in a Czech Slavic cohort
Mária Tomková, Satya Prakash Panda, Ondřej Šeda, Alice Baxová, Martina Hůlková, Bettie Sue Siler Masters, Pavel Martásek
Pharmacogenomics. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Pharmacogenomics. 2015; 16(3): 205–215. doi: 10.2217/pgs.14.169
PMCID:
PMC4662547
ArticlePDF–1.2M
15.
Consequences of POR mutations and polymorphisms
Walter L. Miller, Vishal Agrawal, Duanpen Sandee, Meng Kian Tee, Ningwu Huang, Ji Ha Choi, Kari Morrissey, Kathleen M. Giacomini
Mol Cell Endocrinol. Author manuscript; available in PMC 2015 Nov 4.
Published in final edited form as: Mol Cell Endocrinol. 2011 Apr 10; 336(0): 174–179. Published online 2010 Nov 9. doi: 10.1016/j.mce.2010.10.022
PMCID:
PMC4632974
ArticlePDF–186K
16.
Functional POR A503V is associated with the risk of bladder cancer in a Chinese population
Xue Xiao, Gaoxiang Ma, Shushu Li, Meilin Wang, Nian Liu, Lan Ma, Zhan Zhang, Haiyan Chu, Zhengdong Zhang, Shou-Lin Wang
Sci Rep. 2015; 5: 11751. Published online 2015 Jun 30. doi: 10.1038/srep11751
PMCID:
PMC4485255
ArticlePDF–1.0M
17.
A Well-Balanced Preexisting Equilibrium Governs Electron Flux Efficiency of a Multidomain Diflavin Reductase
Oriane Frances, Fataneh Fatemi, Denis Pompon, Eric Guittet, Christina Sizun, Javier Pérez, Ewen Lescop, Gilles Truan
Biophys J. 2015 Mar 24; 108(6): 1527–1536. doi: 10.1016/j.bpj.2015.01.032
PMCID:
PMC4375552
ArticlePDF–2.0M
18.
Identification of six novel P450 oxidoreductase missense variants in Ashkenazi and Moroccan Jewish populations
Mária Tomková, Christopher C Marohnic, David Gurwitz, Ondřej Šeda, Bettie Sue Siler Masters, Pavel Martásek
Pharmacogenomics. Author manuscript; available in PMC 2014 Dec 18.
Published in final edited form as: Pharmacogenomics. 2012 Apr; 13(5): 543–554. doi: 10.2217/pgs.12.21
PMCID:
PMC4270371
ArticlePDF–1.0M
19.
Pharmacogenomics of human P450 oxidoreductase
Amit V. Pandey, Patrick Sproll
Front Pharmacol. 2014; 5: 103. Published online 2014 May 9. doi: 10.3389/fphar.2014.00103
PMCID:
PMC4023047
ArticlePDF–2.8M
20.
NADPH-Cytochrome P450 Reductase Is Regulated by All-Trans Retinoic Acid and by 1,25-Dihydroxyvitamin D3 in Human Acute Myeloid Leukemia Cells
Elżbieta Gocek, Aleksandra Marchwicka, Kamila Bujko, Ewa Marcinkowska
PLoS One. 2014; 9(3): e91752. Published online 2014 Mar 18. doi: 10.1371/journal.pone.0091752
PMCID:
PMC3958372
ArticlePDF–635K

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