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Select item 96976571.

iPLA2β-Null Mice Show HCC Protection by an Induction of Cell-Cycle Arrest after Diethylnitrosamine Treatment

Adriana Andrade, Tanja Poth, Alexander Brobeil, Uta Merle, Walee Chamulitrat

Int J Mol Sci. 2022 Nov; 23(22): 13760. Published online 2022 Nov 9. doi: 10.3390/ijms232213760

PMCID:: PMC9697657

Article PDF–1.7M

Select item 75659682.

Rescue of Hepatic Phospholipid Remodeling Defect in iPLA₂β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver

Walee Chamulitrat, Chutima Jansakun, Huili Li, Gerhard Liebisch

Biomolecules. 2020 Sep; 10(9): 1332. Published online 2020 Sep 17. doi: 10.3390/biom10091332

PMCID:: PMC7565968

Article PDF–3.2M

Select item 67216603.

iPla2β Deficiency Suppresses Hepatic ER UPR, Fxr, and Phospholipids in Mice Fed with MCD Diet, Resulting in Exacerbated Hepatic Bile Acids and Biliary Cell Proliferation

Yanan Ming, Xingya Zhu, Sabine Tuma-Kellner, Alexandra Ganzha, Gerhard Liebisch, Hongying Gan-Schreier, Walee Chamulitrat

Cells. 2019 Aug; 8(8): 879. Published online 2019 Aug 12. doi: 10.3390/cells8080879

PMCID:: PMC6721660

Article PDF–3.0M

Select item 66233674.

Neuroaxonal Dystrophy in Calcium-Independent Phospholipase A₂β Deficiency Results from Insufficient Remodeling and Degeneration of Mitochondrial and Presynaptic Membranes

Goichi Beck, Yuki Sugiura, Koei Shinzawa, Shinsuke Kato, Mitsutoshi Setou, Yoshihide Tsujimoto, Saburo Sakoda, Hisae Sumi-Akamaru

J Neurosci. 2011 Aug 3; 31(31): 11411–11420. doi: 10.1523/JNEUROSCI.0345-11.2011

PMCID:: PMC6623367

Article PDF–7.3M

Select item 50877435.

Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA₂β (Group VIA Phospholipase A₂)

Jason W. Ashley, William D. Hancock, Alexander J. Nelson, Robert N. Bone, Hubert M. Tse, Mary Wohltmann, John Turk, Sasanka Ramanadham

J Biol Chem. 2016 Oct 28; 291(44): 23268–23281. Published online 2016 Sep 20. doi: 10.1074/jbc.M116.754945

PMCID:: PMC5087743

Article PDF–1.8M

Select item 48317826.

Progressive Axonal Degeneration of Nigrostriatal Dopaminergic Neurons in Calcium-Independent Phospholipase A₂β Knockout Mice

Goichi Beck, Koei Shinzawa, Hideki Hayakawa, Kousuke Baba, Hisae Sumi-Akamaru, Yoshihide Tsujimoto, Hideki Mochizuki

PLoS One. 2016; 11(4): e0153789. Published online 2016 Apr 14. doi: 10.1371/journal.pone.0153789

PMCID:: PMC4831782

Article PDF–29M

Select item 48074767.

Mice with Genetic Deletion of Group VIA Phospholipase A₂β Exhibit Impaired Macrophage Function and Increased Parasite Load in Trypanosoma cruzi-Induced Myocarditis

Janhavi Sharma, Jennifer R. Blase, Daniel F. Hoft, John O. Marentette, John Turk, Jane McHowat

Infect Immun. 2016 Apr; 84(4): 1137–1142. Prepublished online 2016 Feb 8. Published online 2016 Mar 24. doi: 10.1128/IAI.01564-15

PMCID:: PMC4807476

Article PDF–1.1M

Select item 43039598.

Inhibition of Ca²⁺-Independent Phospholipase A₂β (iPLA₂β) Ameliorates Islet Infiltration and Incidence of Diabetes in NOD Mice

Robert N. Bone, Ying Gai, Victoria Magrioti, Maroula G. Kokotou, Tomader Ali, Xiaoyong Lei, Hubert M. Tse, George Kokotos, Sasanka Ramanadham

Diabetes. 2015 Feb; 64(2): 541–554. Published online 2014 Sep 11. doi: 10.2337/db14-0097

PMCID:: PMC4303959

Article PDF–1.9M

Select item 41894609.

Global Inactivation of the Pla2g6 Gene in Mice Does Not Cause Dyslipidemia under Chow or High-fat Diet Conditions

Li Zhang, Shumei Zhong, Ying Li, Guang Ji, Meenakshi Sundaram, Zemin Yao

J Cancer Prev. 2013 Sep; 18(3): 235–248. doi: 10.15430/JCP.2013.18.3.235

PMCID:: PMC4189460

Article PDF–2.7M

Select item 339380610.

Disturbed brain phospholipid and docosahexaenoic acid metabolism in calcium-independent phospholipase A₂-VIA (iPLA₂β)-knockout mice

Yewon Cheon, Hyung-Wook Kim, Miki Igarashi, Hiren R. Modi, Lisa Chang, Kaizong Ma, Deanna Greenstein, Mary Wohltmann, John Turk, Stanley I Rapoport, Ameer Y. Taha

Biochim Biophys Acta. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Biochim Biophys Acta. 2012 Sep; 1821(9): 1278–1286. Published online 2012 Feb 10. doi: 10.1016/j.bbalip.2012.02.003

PMCID:: PMC3393806

Article PDF–668K

Select item 334937011.

Lung endothelial cell platelet-activating factor production and inflammatory cell adherence are increased in response to cigarette smoke component exposure

Janhavi Sharma, Dawn M. Young, John O. Marentette, Prerna Rastogi, John Turk, Jane McHowat

Am J Physiol Lung Cell Mol Physiol. 2012 Jan 1; 302(1): L47–L55. Published online 2011 Oct 7. doi: 10.1152/ajplung.00179.2011

PMCID:: PMC3349370

Article

Select item 328278012.

iPLA₂β Overexpression in Smooth Muscle Exacerbates Angiotensin II-Induced Hypertension and Vascular Remodeling

Lindsay E. Calderon, Shu Liu, Wen Su, Zhongwen Xie, Zhenheng Guo, Wanda Eberhard, Ming C. Gong

PLoS One. 2012; 7(2): e31850. Published online 2012 Feb 20. doi: 10.1371/journal.pone.0031850

PMCID:: PMC3282780

Article PDF–818K

Select item 320393513.

Genetic Ablation of PLA2G6 in Mice Leads to Cerebellar Atrophy Characterized by Purkinje Cell Loss and Glial Cell Activation

Zhengshan Zhao, Jing Wang, Chunying Zhao, Weina Bi, Zhenyu Yue, Zhongmin Alex Ma

PLoS One. 2011; 6(10): e26991. Published online 2011 Oct 28. doi: 10.1371/journal.pone.0026991

PMCID:: PMC3203935

Article PDF–3.4M

Select item 307463414.

Platelet-activating factor and metastasis: calcium-independent phospholipase A₂β deficiency protects against breast cancer metastasis to the lung

Jane McHowat, Gail Gullickson, Richard G. Hoover, Janhavi Sharma, John Turk, Jacki Kornbluth

Am J Physiol Cell Physiol. 2011 Apr; 300(4): C825–C832. Published online 2011 Jan 12. doi: 10.1152/ajpcell.00502.2010

PMCID:: PMC3074634

Article

Select item 299690015.

Group VIA phospholipase A₂ in both host and tumor cells is involved in ovarian cancer development

Hui Li, Zhenwen Zhao, Gang Wei, Libo Yan, Dongmei Wang, Hong Zhang, George Earl Sandusky, John Turk, Yan Xu

FASEB J. 2010 Oct; 24(10): 4103–4116. doi: 10.1096/fj.10-161356

Correction in:: FASEB J. 2015 Jan; 29(1): 354.

PMCID:: PMC2996900

Article

Select item 295255716.

Imaging decreased brain docosahexaenoic acid metabolism and signaling in iPLA₂β (VIA)-deficient mice

Mireille Basselin, Angelo O. Rosa, Epolia Ramadan, Yewon Cheon, Lisa Chang, Mei Chen, Deanna Greenstein, Mary Wohltmann, John Turk, Stanley I. Rapoport

J Lipid Res. 2010 Nov; 51(11): 3166–3173. doi: 10.1194/jlr.M008334

PMCID:: PMC2952557

Article PDF–743K

Select item 293818717.

Endothelial Cell Prostaglandin I₂ and Platelet-Activating Factor Production Are Markedly Attenuated in the Calcium-Independent Phospholipase A₂β Knockout Mouse

Janhavi Sharma, John Turk, Jane McHowat

Biochemistry. Author manuscript; available in PMC 2011 Jul 6.

Published in final edited form as: Biochemistry. 2010 Jul 6; 49(26): 5473–5481. doi: 10.1021/bi100752u

PMCID:: PMC2938187

Article PDF–1.8M

Select item 290393418.

Protection of Pancreatic β-Cells by Group VIA Phospholipase A₂-Mediated Repair of Mitochondrial Membrane Peroxidation

Zhengshan Zhao, Xu Zhang, Chunying Zhao, Jinwoo Choi, Jieyi Shi, Keying Song, John Turk, Zhongmin Alex Ma

Endocrinology. 2010 Jul; 151(7): 3038–3048. Published online 2010 Mar 12. doi: 10.1210/en.2010-0016

Correction in:: Endocrinology. 2011 Jan 1; 152(1): 336.

PMCID:: PMC2903934

Article

Select item 288665819.

Genetic ablation of calcium-independent phospholipase A₂β causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine

Hans H. Dietrich, Dana R. Abendschein, Sung Ho Moon, Neema Nayeb-Hashemi, David J. Mancuso, Christopher M. Jenkins, Kevin M. Kaltenbronn, Kendall J. Blumer, John Turk, Richard W. Gross

Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6): H2208–H2220. Published online 2010 Apr 9. doi: 10.1152/ajpheart.00839.2009