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Select item 66496671.

Irreversible APC^Cdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry

Steven D. Cappell, Mingyu Chung, Ariel Jaimovich, Sabrina L. Spencer, Tobias Meyer

Cell. Author manuscript; available in PMC 2019 Jul 23.

Published in final edited form as: Cell. 2016 Jun 30; 166(1): 167–180. doi: 10.1016/j.cell.2016.05.077

PMCID:: PMC6649667

Article PDF–1.7M

Select item 52170132.

Suppression of APC/C^Cdh1 has subtype specific biological effects in acute myeloid leukemia

Daniel Ewerth, Andrea Schmidts, Manuel Hein, Dominik Schnerch, Arunas Kvainickas, Christine Greil, Justus Duyster, Monika Engelhardt, Ralph Wäsch

Oncotarget. 2016 Jul 26; 7(30): 48220–48230. Published online 2016 Jun 21. doi: 10.18632/oncotarget.10196

PMCID:: PMC5217013

Article PDF–5.1M

Select item 49332643.

O-GlcNAcylation Antagonizes Phosphorylation of CDH1 (CDC20 Homologue 1)

Jie Tian, Qizhi Geng, Yuehe Ding, Ji Liao, Meng-Qiu Dong, Xingzhi Xu, Jing Li

J Biol Chem. 2016 Jun 3; 291(23): 12136–12144. Published online 2016 Apr 14. doi: 10.1074/jbc.M116.717850

PMCID:: PMC4933264

Article PDF–1.6M

Select item 48899304.

New origin firing is inhibited by APC/C^Cdh1 activation in S-phase after severe replication stress

Amaia Ercilla, Alba Llopis, Sonia Feu, Sergi Aranda, Patrik Ernfors, Raimundo Freire, Neus Agell

Nucleic Acids Res. 2016 Jun 2; 44(10): 4745–4762. Published online 2016 Mar 2. doi: 10.1093/nar/gkw132

PMCID:: PMC4889930

Article PDF–7.1M

Select item 39236375.

Uncovering the role of APC-Cdh1 in generating the dynamics of S-phase onset

Xi Yuan, Jeyaraman Srividhya, Thomas De Luca, Ju-hyong E. Lee, Joseph R. Pomerening

Mol Biol Cell. 2014 Feb 15; 25(4): 441–456. doi: 10.1091/mbc.E13-08-0480

PMCID:: PMC3923637

Article PDF–6.9M

Select item 29738766.

Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes

Sergio L. Colombo, Miriam Palacios-Callender, Nanci Frakich, Joel De Leon, Christoph A. Schmitt, Leanne Boorn, Nicola Davis, Salvador Moncada

Proc Natl Acad Sci U S A. 2010 Nov 2; 107(44): 18868–18873. Published online 2010 Oct 4. doi: 10.1073/pnas.1012362107

PMCID:: PMC2973876

Article PDF–874K

Select item 863217.

Nonperiodic Activity of the Human Anaphase-Promoting Complex–Cdh1 Ubiquitin Ligase Results in Continuous DNA Synthesis Uncoupled from Mitosis

Claus Storgaard Sørensen, Claudia Lukas, Edgar R. Kramer, Jan-Michael Peters, Jiri Bartek, Jiri Lukas

Mol Cell Biol. 2000 Oct; 20(20): 7613–7623. doi: 10.1128/mcb.20.20.7613-7623.2000

PMCID:: PMC86321

Article PDF–2.1M

Select item 99264688.

Structural investigation of CDCA3‐Cdh1 protein–protein interactions using in vitro studies and molecular dynamics simulation

Tabassum Khair Barbhuiya, Mark Fisher, Eric D. Boittier, Emma Bolderson, Kenneth J. O'Byrne, Derek J. Richard, Mark Nathaniel Adams, Neha S. Gandhi

Protein Sci. 2023 Mar; 32(3): e4572. Published online 2023 Feb 14. doi: 10.1002/pro.4572

PMCID:: PMC9926468

Article PDF–2.7M

Select item 91665429.

De novo FZR1 loss-of-function variants cause developmental and epileptic encephalopathies

Sathiya N Manivannan, Jolien Roovers, Noor Smal, Candace T Myers, Dilsad Turkdogan, Filip Roelens, Oguz Kanca, Hyung-Lok Chung, Tasja Scholz, Katharina Hermann, Tatjana Bierhals, Hande S Caglayan, Hannah Stamberger, MAE Working Group of EuroEPINOMICS RES Consortium , Heather Mefford, Peter de Jonghe, Shinya Yamamoto, Sarah Weckhuysen, Hugo J Bellen

Brain. 2022 May; 145(5): 1684–1697. Published online 2021 Nov 11. doi: 10.1093/brain/awab409

PMCID:: PMC9166542

Article PDF–1.7M

Select item 769920310.

E3 Ubiquitin Ligase APC/C^Cdh1 Negatively Regulates FAH Protein Stability by Promoting Its Polyubiquitination

Kamini Kaushal, Sang Hyeon Woo, Apoorvi Tyagi, Dong Ha Kim, Bharathi Suresh, Kye-Seong Kim, Suresh Ramakrishna

Int J Mol Sci. 2020 Nov; 21(22): 8719. Published online 2020 Nov 18. doi: 10.3390/ijms21228719

PMCID:: PMC7699203

Article PDF–10M

Select item 743460411.

Whole‐exome sequencing and genome‐wide association studies identify novel sarcopenia risk genes in Han Chinese

Shu Ran, Xiao He, Zi‐Xuan Jiang, Yu Liu, Yu‐Xue Zhang, Lei Zhang, Gui‐Shan Gu, Yufang Pei, Bao‐Lin Liu, Qing Tian, Yong‐Hong Zhang, Jing‐Yu Wang, Hong‐Wen Deng

Mol Genet Genomic Med. 2020 Aug; 8(8): e1267. Published online 2020 Jun 1. doi: 10.1002/mgg3.1267

PMCID:: PMC7434604

Article PDF–1.1M

Select item 700033712.

Cdh1-mediated Skp2 degradation by dioscin reprogrammes aerobic glycolysis and inhibits colorectal cancer cells growth

Li Zhou, Xinfang Yu, Ming Li, Guanghui Gong, Wenbin Liu, Tian Li, Huilan Zuo, Wei Li, Feng Gao, Haidan Liu

EBioMedicine. 2020 Jan; 51: 102570. Published online 2019 Dec 2. doi: 10.1016/j.ebiom.2019.11.031

PMCID:: PMC7000337

Article PDF–3.1M

Select item 538665113.

Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells

Junzhang Zhao, Rui Zhou, Kaiyuan Hui, Yang Yang, QiuYue Zhang, Yali Ci, Lei Shi, Caimin Xu, Fang Huang, Yu Hu

Oncotarget. 2017 Mar 21; 8(12): 18832–18847. Published online 2016 Nov 25. doi: 10.18632/oncotarget.13600

PMCID:: PMC5386651

Article PDF–2.6M

Select item 538386714.

FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia

Jo Ishizawa, Eiji Sugihara, Shinji Kuninaka, Kaoru Mogushi, Kensuke Kojima, Christopher B. Benton, Ran Zhao, Dhruv Chachad, Norisato Hashimoto, Rodrigo O. Jacamo, Yihua Qiu, Suk Young Yoo, Shinichiro Okamoto, Michael Andreeff, Steven M. Kornblau, Hideyuki Saya

Blood. 2017 Apr 6; 129(14): 1958–1968. Prepublished online 2017 Jan 31. doi: 10.1182/blood-2016-07-726216

PMCID:: PMC5383867

Article

Select item 534256715.

Identification of the APC/C co-factor FZR1 as a novel therapeutic target for multiple myeloma

Lisa J. Crawford, Gordon Anderson, Cliona K. Johnston, Alexandra E. Irvine

Oncotarget. 2016 Oct 25; 7(43): 70481–70493. Published online 2016 Sep 15. doi: 10.18632/oncotarget.12026

PMCID:: PMC5342567

Article PDF–2.8M

Select item 502581216.

APC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathway

Ajeena Ramanujan, Swati Tiwari

Biosci Rep. 2016 Oct; 36(5): e00377. Prepublished online 2016 Jul 8. Published online 2016 Sep 16. doi: 10.1042/BSR20160152

PMCID:: PMC5025812

Article PDF–752K

Select item 488927717.

TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth

Savvas C. Pavlides, Jon Lecanda, Julien Daubriac, Unnati M. Pandya, Patricia Gama, Stephanie Blank, Khushbakhat Mittal, Pratibha Shukla, Leslie I. Gold

Cell Cycle. 2016; 15(7): 931–947. Published online 2016 Mar 10. doi: 10.1080/15384101.2016.1150393