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Select item 85826721.

Role of the Purinergic P2Y2 Receptor in Pulmonary Hypertension

Mazen Shihan, Tatyana Novoyatleva, Thilo Lehmeyer, Akylbek Sydykov, Ralph T. Schermuly

Int J Environ Res Public Health. 2021 Nov; 18(21): 11009. Published online 2021 Oct 20. doi: 10.3390/ijerph182111009

PMCID:: PMC8582672

Article PDF–4.1M

Select item 85337262.

Quantitative Super-Resolution Imaging for the Analysis of GPCR Oligomerization

Megan D. Joseph, Elena Tomas Bort, Richard P. Grose, Peter J. McCormick, Sabrina Simoncelli

Biomolecules. 2021 Oct; 11(10): 1503. Published online 2021 Oct 12. doi: 10.3390/biom11101503

PMCID:: PMC8533726

Article PDF–4.2M

Select item 81062943.

Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY2

Masaki Takahashi, Ryo Amano, Michiru Ozawa, Anna Martinez, Kazumasa Akita, Yoshikazu Nakamura

Proc Natl Acad Sci U S A. 2021 May 4; 118(18): e2019497118. Published online 2021 Apr 28. doi: 10.1073/pnas.2019497118

PMCID:: PMC8106294

Article PDF–1.2M

Select item 67545454.

P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells

Saisai Chen, Thomas Shenk, Maciej T. Nogalski

Proc Natl Acad Sci U S A. 2019 Sep 17; 116(38): 18971–18982. Published online 2019 Sep 3. doi: 10.1073/pnas.1907562116

PMCID:: PMC6754545

Article PDF–2.0M

Select item 61927885.

P2Y₂R-mediated inflammasome activation is involved in tumor progression in breast cancer cells and in radiotherapy-resistant breast cancer

Hana Jin, Young Shin Ko, Hye Jung Kim

Int J Oncol. 2018 Nov; 53(5): 1953–1966. Published online 2018 Sep 4. doi: 10.3892/ijo.2018.4552

PMCID:: PMC6192788

Article PDF–1.0M

Select item 57835966.

P2Y2 receptor promotes the migration and invasion of breast cancer cells via EMT-related genes Snail and E-cadherin

Ying Qiu, Yan Liu, Wei-Hua Li, Hong-Quan Zhang, Xin-Xia Tian, Wei-Gang Fang

Oncol Rep. 2018 Jan; 39(1): 138–150. Published online 2017 Nov 7. doi: 10.3892/or.2017.6081

PMCID:: PMC5783596

Article PDF–1.2M

Select item 57267677.

P2Y₂ Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling

Farid G. Khalafalla, Steven Greene, Hashim Khan, Kelli Ilves, Megan Monsanto, Roberto Alvarez, Jr., Monica Chavarria, Jonathan Nguyen, Benjamin Norman, Walter P. Dembitsky, Mark A. Sussman

Circ Res. Author manuscript; available in PMC 2018 Nov 10.

Published in final edited form as: Circ Res. 2017 Nov 10; 121(11): 1224–1236. Published online 2017 Sep 18. doi: 10.1161/CIRCRESAHA.117.310812

PMCID:: PMC5726767

Article PDF–1.5M

Select item 52729058.

P2Y₂ receptor modulates shear stress-induced cell alignment and actin stress fibers in human umbilical vein endothelial cells

Ramasri Sathanoori, Paulina Bryl-Gorecka, Christa E. Müller, Laurie Erb, Gary A. Weisman, Björn Olde, David Erlinge

Cell Mol Life Sci. 2017; 74(4): 731–746. Published online 2016 Sep 20. doi: 10.1007/s00018-016-2365-0

PMCID:: PMC5272905

Article PDF–15M

Select item 51428379.

Endothelial P2Y₂ receptor regulates LPS-induced neutrophil transendothelial migration in vitro

Filip Kukulski, Fethia Ben Yebdri, Fariborz Bahrami, Michel Fausther, Alain Tremblay, Jean Sévigny

Mol Immunol. Author manuscript; available in PMC 2016 Dec 7.

Published in final edited form as: Mol Immunol. 2010 Feb; 47(5): 991–999. Published online 2009 Dec 21. doi: 10.1016/j.molimm.2009.11.020

PMCID:: PMC5142837

Article PDF–1024K

Select item 440601210.

P2Y₂receptor activation by nucleotides released from highly metastatic breast cancer cells increases tumor growth and invasion via crosstalk with endothelial cells

Hana Jin, So Young Eun, Jong Sil Lee, Sang Won Park, Jae Heun Lee, Ki Churl Chang, Hye Jung Kim

Breast Cancer Res. 2014; 16: R77. Published online 2014 Aug 26. doi: 10.1186/bcr3694

PMCID:: PMC4406012

Article PDF–1.9M

Select item 425343711.

P2Y₂R activation by nucleotides released from the highly metastatic breast cancer cell contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment

Young Nak Joo, Hana Jin, So Young Eun, Sang Won Park, Ki Churl Chang, Hye Jung Kim

Oncotarget. 2014 Oct; 5(19): 9322–9334. Published online 2014 Sep 2. doi: 10.18632/oncotarget.2427

PMCID:: PMC4253437

Article PDF–2.8M

Select item 408195012.

The P2Y₂ Nucleotide Receptor Mediates the Proliferation and Migration of Human Hepatocellular Carcinoma Cells Induced by ATP

Rui Xie, Jingyu Xu, Guorong Wen, Hai Jin, Xuemei Liu, Yuan Yang, Bei Ji, Yixia Jiang, Penghong Song, Hui Dong, Biguang Tuo

J Biol Chem. 2014 Jul 4; 289(27): 19137–19149. Published online 2014 May 20. doi: 10.1074/jbc.M113.540047

PMCID:: PMC4081950

Article PDF–4.9M

Select item 407835813.

The inhibitory effects of extracellular ATP on the growth of nasopharyngeal carcinoma cells via P2Y2 receptor and osteopontin

Guang Yang, Shenghong Zhang, Yanling Zhang, Qiming Zhou, Sheng Peng, Tao Zhang, Changfu Yang, Zhenyu Zhu, Fujun Zhang

J Exp Clin Cancer Res. 2014; 33(1): 53. Published online 2014 Jun 24. doi: 10.1186/1756-9966-33-53

PMCID:: PMC4078358

Article PDF–3.7M

Select item 395490414.

Loss of P2Y₂ Nucleotide Receptors Enhances Early Pathology in the TgCRND8 Mouse Model of Alzheimer’s Disease

Deepa Ajit, Lucas T. Woods, Jean M. Camden, Christina N. Thebeau, Farid G. El-Sayed, W. Greeson Glen, Laurie Erb, Michael J. Petris, Douglas C. Miller, Grace Y. Sun, Gary A. Weisman

Mol Neurobiol. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Mol Neurobiol. 2014 Apr; 49(2): 1031–1042. Published online 2013 Nov 6. doi: 10.1007/s12035-013-8577-5

PMCID:: PMC3954904

Article PDF–1.3M

Select item 379186515.

Mechanosensitive ATP Release Maintains Proper Mucus Hydration of Airways

Brian Button, Seiko F. Okada, Charles Brandon Frederick, William R. Thelin, Richard C. Boucher

Sci Signal. Author manuscript; available in PMC 2014 Jun 11.

Published in final edited form as: Sci Signal. 2013 Jun 11; 6(279): ra46. Published online 2013 Jun 11. doi: 10.1126/scisignal.2003755

PMCID:: PMC3791865

Article PDF–1.5M

Select item 356843316.

Association of P2Y₂ receptor SNPs with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

Anke Wesselius, Martijn J. L. Bours, Zanne Henriksen, Susanne Syberg, Solveig Petersen, Peter Schwarz, Niklas R. Jørgensen, Svenhjalmar van Helden, Pieter C. Dagnelie

Purinergic Signal. 2013 Mar; 9(1): 41–49. Published online 2012 Jul 8. doi: 10.1007/s11302-012-9326-3

PMCID:: PMC3568433

Article PDF–337K

Select item 340481217.

Molecular Modeling of the Human P2Y₂ Receptor and Design of a Selective Agonist, 2′-Amino-2′-deoxy-2-thio-UTP

Andrei A. Ivanov, Hyojin Ko, Liesbet Cosyn, Savitri Maddileti, Pedro Besada, Ingrid Fricks, Stefano Costanzi, T. Kendall Harden, Serge Van Calenbergh, Kenneth A. Jacobson

J Med Chem. Author manuscript; available in PMC 2012 Jul 25.

Published in final edited form as: J Med Chem. 2007 Mar 22; 50(6): 1166–1176. Published online 2007 Feb 16. doi: 10.1021/jm060903o