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Select item 68624281.

Single-Channel Properties of the ROMK-Pore-Forming Subunit of the Mitochondrial ATP-Sensitive Potassium Channel

Michał Laskowski, Bartłomiej Augustynek, Piotr Bednarczyk, Monika Żochowska, Justyna Kalisz, Brian O’Rourke, Adam Szewczyk, Bogusz Kulawiak

Int J Mol Sci. 2019 Nov; 20(21): 5323. Published online 2019 Oct 25. doi: 10.3390/ijms20215323

PMCID:: PMC6862428

Abstract Article PDF–2.8M

Select item 58361122.

The endosomal trafficking factors CORVET and ESCRT suppress plasma membrane residence of the renal outer medullary potassium channel (ROMK)

Timothy D. Mackie, Bo-Young Kim, Arohan R. Subramanya, Daniel J. Bain, Allyson F. O'Donnell, Paul A. Welling, Jeffrey L. Brodsky

J Biol Chem. 2018 Mar 2; 293(9): 3201–3217. Published online 2018 Jan 8. doi: 10.1074/jbc.M117.819086

PMCID:: PMC5836112

Abstract Article PDF–2.6M

Select item 37226753.

Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions

Najaf Amin, Jouke-Jan Hottenga, Narelle K Hansell, A Cecile JW Janssens, Marleen HM de Moor, Pamela AF Madden, Irina V Zorkoltseva, Brenda W Penninx, Antonio Terracciano, Manuela Uda, Toshiko Tanaka, Tonu Esko, Anu Realo, Luigi Ferrucci, Michelle Luciano, Gail Davies, Andres Metspalu, Goncalo R Abecasis, Ian J Deary, Katri Raikkonen, Laura J Bierut, Paul T Costa, Viatcheslav Saviouk, Gu Zhu, Anatoly V Kirichenko, Aaron Isaacs, Yurii S Aulchenko, Gonneke Willemsen, Andrew C Heath, Michele L Pergadia, Sarah E Medland, Tatiana I Axenovich, Eco de Geus, Grant W Montgomery, Margaret J Wright, Ben A Oostra, Nicholas G Martin, Dorret I Boomsma, Cornelia M van Duijn

Eur J Hum Genet. 2013 Aug; 21(8): 876–882. Published online 2012 Dec 5. doi: 10.1038/ejhg.2012.263

PMCID:: PMC3722675

Abstract Article PDF–383K

Select item 35297424.

Association of KCNJ1 variation with change in fasting glucose and new onset diabetes during HCTZ treatment

JH Karnes, CW McDonough, Y Gong, TT Vo, TY Langaee, AB Chapman, JG Gums, AL Beitelshees, KR Bailey, JL Del-Aguila, EA Boerwinkle, CJ Pepine, ST Turner, JA Johnson, RM Cooper-DeHoff

Pharmacogenomics J. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Pharmacogenomics J. 2013 Oct; 13(5): 430–436. Published online 2012 Aug 21. doi: 10.1038/tpj.2012.34

PMCID:: PMC3529742

Abstract Article PDF–441K

Select item 30475075.

Protein Kinase C (PKC)-induced Phosphorylation of ROMK1 Is Essential for the Surface Expression of ROMK1 Channels

DaoHong Lin, Hyacinth Sterling, Kenneth M. Lerea, Gerhard Giebisch, Wen-Hui Wang

J Biol Chem. Author manuscript; available in PMC 2011 Mar 2.

Published in final edited form as: J Biol Chem. 2002 Nov 15; 277(46): 44278–44284. Published online 2002 Sep 6. doi: 10.1074/jbc.M203702200

PMCID:: PMC3047507

Abstract Article PDF–752K

Select item 26729386.

Structural changes in the cytoplasmic pore of the Kir1.1 channel during pH_i-gating probed by FRET

Jay-Ron Lee, Ru-Chi Shieh

J Biomed Sci. 2009; 16(1): 29. Published online 2009 Mar 6. doi: 10.1186/1423-0127-16-29

PMCID:: PMC2672938

Abstract Article PDF–833K

Select item 22906107.

Molecular mechanism of a COOH-terminal gating determinant in the ROMK channel revealed by a Bartter's disease mutation

Thomas P Flagg, Dana Yoo, Christopher M Sciortino, Margaret Tate, Michael F Romero, Paul A Welling

J Physiol. 2002 Oct 15; 544(Pt 2): 351–362. Published online 2002 Sep 13. doi: 10.1113/jphysiol.2002.027581

PMCID:: PMC2290610

Abstract Article PDF–490K

Select item 11750148.

Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K⁺ channel (ROMK)

Anthony D. O'Connell, Qiang Leng, Ke Dong, Gordon G. MacGregor, Gerhard Giebisch, Steven C. Hebert

Proc Natl Acad Sci U S A. 2005 Jul 12; 102(28): 9954–9959. Published online 2005 Jun 29. doi: 10.1073/pnas.0504332102

PMCID:: PMC1175014

Abstract Article PDF–395K

Select item 55460249.

Endoplasmic reticulum–associated degradation of the renal potassium channel, ROMK, leads to type II Bartter syndrome

Brighid M. O'Donnell, Timothy D. Mackie, Arohan R. Subramanya, Jeffrey L. Brodsky

J Biol Chem. 2017 Aug 4; 292(31): 12813–12827. Published online 2017 Jun 19. doi: 10.1074/jbc.M117.786376

PMCID:: PMC5546024

Abstract Article PDF–2.7M

Select item 419541710.

Calcium Intake and Ion Transporter Genetic Polymorphisms Interact in Human Colorectal Neoplasia Risk in a 2-Phase Study

Xiangzhu Zhu, Ji Liang, Martha J. Shrubsole, Reid M. Ness, Qiuyin Cai, Jirong Long, Zhi Chen, Guoliang Li, Dawn Wiese, Bing Zhang, Walter E. Smalley, Todd L. Edwards, Edward Giovannucci, Wei Zheng, Qi Dai

J Nutr. 2014 Nov; 144(11): 1734–1741. Published online 2014 Aug 27. doi: 10.3945/jn.114.196709

PMCID:: PMC4195417

Abstract Article PDF–516K

Select item 305500011.

Heterozygous mutations of the gene for Kir 1.1 (ROMK) in antenatal Bartter syndrome presenting with transient hyperkalemia, evolving to a benign course.

Jong Tae Cho, Lisa Marie Guay-Woodford

J Korean Med Sci. 2003 Feb; 18(1): 65–68. doi: 10.3346/jkms.2003.18.1.65

PMCID:: PMC3055000

Summary PDF–93K

Select item 251918112.

Domains of WNK1 kinase in the regulation of ROMK1

Hao-Ran Wang, Zhen Liu, Chou-Long Huang

Am J Physiol Renal Physiol. 2008 Aug; 295(2): F438–F445. Published online 2008 Jun 11. doi: 10.1152/ajprenal.90287.2008

PMCID:: PMC2519181

Abstract Article

Select item 182106613.

Intersectin links WNK kinases to endocytosis of ROMK1

Guocheng He, Hao-Ran Wang, Shao-Kuei Huang, Chou-Long Huang

J Clin Invest. 2007 Apr 2; 117(4): 1078–1087. Published online 2007 Mar 22. doi: 10.1172/JCI30087

PMCID:: PMC1821066

Abstract Article PDF–1.3M

Select item 1037478614.

Association of polymorphisms of calcium reabsorption genes SLC12A1, KCNJ1 and SLC8A1 with colorectal adenoma

Xiaolian Lai, Shuoyan Lu, Jia Jiang, Hanqun Zhang, Qinglin Yang, Yuncong Liu, Libo Li, Sanming Li, Si Dai, Yanping Chen, Yan Chen, Jun Liu, Yong Li

J Cancer Res Clin Oncol. 2023; 149(11): 8335–8344. Published online 2023 Apr 19. doi: 10.1007/s00432-023-04773-4

PMCID:: PMC10374786

Abstract Article PDF–639K

Select item 611300315.

Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation

Priyanka Nandakumar, Alanna C. Morrison, Megan L. Grove, Eric Boerwinkle, Aravinda Chakravarti

Medicine (Baltimore) 2018 Aug; 97(33): e11865. Published online 2018 Aug 17. doi: 10.1097/MD.0000000000011865

PMCID:: PMC6113003

Abstract Article PDF–595K

Select item 439429016.

Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK)

Dao-Hong Lin, Peng Yue, Orlando Yarborough, III, Ute I. Scholl, Gerhard Giebisch, Richard P. Lifton, Jesse Rinehart, Wen-Hui Wang

Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14): 4495–4500. Published online 2015 Mar 24. doi: 10.1073/pnas.1503437112

PMCID:: PMC4394290

Abstract Article PDF–905K

Select item 273640417.

Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels

Peng Yue, Dao-Hong Lin, Chun-Yang Pan, Qiang Leng, Gerhard Giebisch, Richard P. Lifton, Wen-Hui Wang

Proc Natl Acad Sci U S A. 2009 Sep 1; 106(35): 15061–15066. Published online 2009 Aug 18. doi: 10.1073/pnas.0907855106

PMCID:: PMC2736404

Abstract Article PDF–506K

Select item 302351818.

Tamm-Horsfall Glycoprotein Interacts with Renal Outer Medullary Potassium Channel ROMK2 and Regulates Its Function

Aparna Renigunta, Vijay Renigunta, Turgay Saritas, Niels Decher, Kerim Mutig, Siegfried Waldegger

J Biol Chem. 2011 Jan 21; 286(3): 2224–2235. Published online 2010 Nov 16. doi: 10.1074/jbc.M110.149880

PMCID:: PMC3023518

Abstract Article PDF–2.4M

Select item 270145219.

Regulation of Renal Outer Medullary Potassium Channel and Renal K⁺ Excretion by Klotho

Seung-Kuy Cha, Ming-Chang Hu, Hiroshi Kurosu, Makoto Kuro-o, Orson Moe, Chou-Long Huang

Mol Pharmacol. 2009 Jul; 76(1): 38–46. Published online 2009 Apr 6. doi: 10.1124/mol.109.055780

PMCID:: PMC2701452

Abstract Article PDF–428K

Select item 267328820.

Regulation of ROMK Channel and K⁺ Homeostasis by Kidney-specific WNK1 Kinase

Zhen Liu, Hao-Ran Wang, Chou-Long Huang

J Biol Chem. 2009 May 1; 284(18): 12198–12206. doi: 10.1074/jbc.M806551200

PMCID:: PMC2673288

Abstract Article PDF–521K

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