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Select item 105811611.

Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer

Wei Wang, Yun Gu, Hao Ni, Qiuying Quan, Lingchuan Guo

Exp Biol Med (Maywood) 2023 Jun; 248(12): 1043–1055. Published online 2023 Apr 24. doi: 10.1177/15353702231160326

PMCID:: PMC10581161

Article PDF–7.9M

Select item 97569842.

Clinicopathological features, prognostic significance, and associated tumor cell functions of family with sequence similarity 111 member B in pancreatic adenocarcinoma

Qi Gong, QingTai Dong, Bin Zhong, Tao Zhang, Ding Cao, Yi Zhang, Dandan Ma, Xun Cai, ZhongHu Li

J Clin Lab Anal. 2022 Dec; 36(12): e24784. Published online 2022 Nov 21. doi: 10.1002/jcla.24784

PMCID:: PMC9756984

Article PDF–2.0M

Select item 93449083.

Mutations within the putative protease domain of the human FAM111B gene may predict disease severity and poor prognosis: A review of POIKTMP cases

Afolake Arowolo, Cenza Rhoda, Nonhlanhla Khumalo

Exp Dermatol. 2022 May; 31(5): 648–654. Published online 2022 Feb 13. doi: 10.1111/exd.14537

PMCID:: PMC9344908

Article PDF–1.1M

Select item 62077584.

Mutations of FAM111B gene are not associated with Systemic Sclerosis

A. Gcelu, G. Deshpande, G. Shaboodien, T. F. Spracklen, A. Kalla, M. Tikly, B. M. Mayosi, B Hodkinson

Sci Rep. 2018; 8: 15988. Published online 2018 Oct 30. doi: 10.1038/s41598-018-34341-7

PMCID:: PMC6207758

Article PDF–811K

Select item 48417545.

FAM111B MUTATION IS ASSOCIATED WITH INHERITED EXOCRINE PANCREATIC DYSFUNCTION

Aaron Seo, Tom Walsh, Ming Lee, Phoenix Ho, Evelyn Kanyu Hsu, Robert Sidbury, Mary-Claire King, Akiko Shimamura

Pancreas. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: Pancreas. 2016 Jul; 45(6): 858–862. doi: 10.1097/MPA.0000000000000529

PMCID:: PMC4841754

Article PDF–451K

Select item 38530046.

Mutations in FAM111B Cause Hereditary Fibrosing Poikiloderma with Tendon Contracture, Myopathy, and Pulmonary Fibrosis

Sandra Mercier, Sébastien Küry, Gasnat Shaboodien, Darren T. Houniet, Nonhlanhla P. Khumalo, Chantal Bou-Hanna, Nathalie Bodak, Valérie Cormier-Daire, Albert David, Laurence Faivre, Dominique Figarella-Branger, Romain K. Gherardi, Elise Glen, Antoine Hamel, Christian Laboisse, Cédric Le Caignec, Pierre Lindenbaum, Armelle Magot, Arnold Munnich, Jean-Marie Mussini, Komala Pillay, Thahira Rahman, Richard Redon, Emmanuelle Salort-Campana, Mauro Santibanez-Koref, Christel Thauvin, Sébastien Barbarot, Bernard Keavney, Stéphane Bézieau, Bongani M. Mayosi

Am J Hum Genet. 2013 Dec 5; 93(6): 1100–1107. doi: 10.1016/j.ajhg.2013.10.013

PMCID:: PMC3853004

Article PDF–1.6M

Select item 109319377.

Unravelling the Intricate Roles of FAM111A and FAM111B: From Protease-Mediated Cellular Processes to Disease Implications

Danielle Naicker, Cenza Rhoda, Falone Sunda, Afolake Arowolo

Int J Mol Sci. 2024 Mar; 25(5): 2845. Published online 2024 Feb 29. doi: 10.3390/ijms25052845

PMCID:: PMC10931937

Article PDF–1.7M

Select item 92950558.

DNMT3B-mediated FAM111B methylation promotes papillary thyroid tumor glycolysis, growth and metastasis

Xiang Zhu, Chunyuan Xue, Xiaofeng Kang, Xiaomeng Jia, Lin Wang, Muhsin H. Younis, Donghui Liu, Nan Huo, Yuchen Han, Zhao Chen, Jing Fu, Chunyu Zhou, Xiaoxiang Yao, Yimeng Du, Weibo Cai, Lei Kang, Zhaohui Lyu

Int J Biol Sci. 2022; 18(11): 4372–4387. Published online 2022 Jul 4. doi: 10.7150/ijbs.72397

PMCID:: PMC9295055

Article PDF–4.1M

Select item 82278109.

Differential Regulation of Cellular FAM111B by Human Adenovirus C Type 5 E1 Oncogenes

Wing-Hang Ip, Britta Wilkens, Anastasia Solomatina, Judith Martin, Michael Melling, Paloma Hidalgo, Luca D. Bertzbach, Thomas Speiseder, Thomas Dobner

Viruses. 2021 Jun; 13(6): 1015. Published online 2021 May 28. doi: 10.3390/v13061015

PMCID:: PMC8227810

Article PDF–1.8M

Select item 753464010.

FAM111 protease activity undermines cellular fitness and is amplified by gain‐of‐function mutations in human disease

Saskia Hoffmann, Satyakrishna Pentakota, Andreas Mund, Peter Haahr, Fabian Coscia, Marta Gallo, Matthias Mann, Nicholas MI Taylor, Niels Mailand

EMBO Rep. 2020 Oct 5; 21(10): e50662. Published online 2020 Aug 9. doi: 10.15252/embr.202050662

PMCID:: PMC7534640

Article PDF–15M

Select item 341203111.

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB

Petra Van Damme, Marta Lasa, Bogdan Polevoda, Cristina Gazquez, Alberto Elosegui-Artola, Duk Soo Kim, Elena De Juan-Pardo, Kimberly Demeyer, Kristine Hole, Esther Larrea, Evy Timmerman, Jesus Prieto, Thomas Arnesen, Fred Sherman, Kris Gevaert, Rafael Aldabe

Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31): 12449–12454. Published online 2012 Jul 18. doi: 10.1073/pnas.1210303109

PMCID:: PMC3412031

Article PDF–958K

Select item 341237812.

Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity

Marija Usenovic, Adam L. Knight, Arpita Ray, Victoria Wong, Kevin R. Brown, Guy A. Caldwell, Kim A. Caldwell, Igor Stagljar, Dimitri Krainc

Hum Mol Genet. 2012 Sep 1; 21(17): 3785–3794. Published online 2012 May 29. doi: 10.1093/hmg/dds206

PMCID:: PMC3412378

Article PDF–534K

Select item 884482713.

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase

Zhifen Zhou, Yujing Li, Huimin Xu, Xiaowei Xie, Zibin He, Song Lin, Ruofei Li, Shouheng Jin, Jun Cui, Hai Hu, Feng Liu, Su Wu, Wenbin Ma, Zhou Songyang

iScience. 2022 Feb 18; 25(2): 103813. Published online 2022 Jan 25. doi: 10.1016/j.isci.2022.103813

PMCID:: PMC8844827

Article PDF–6.0M

Select item 302349414.

RioK1, a New Interactor of Protein Arginine Methyltransferase 5 (PRMT5), Competes with pICln for Binding and Modulates PRMT5 Complex Composition and Substrate Specificity

Gernot Guderian, Christoph Peter, Julia Wiesner, Albert Sickmann, Klaus Schulze-Osthoff, Utz Fischer, Matthias Grimmler

J Biol Chem. 2011 Jan 21; 286(3): 1976–1986. Published online 2010 Nov 16. doi: 10.1074/jbc.M110.148486

PMCID:: PMC3023494

Article PDF–4.1M

Select item 804593215.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Article PDF–1.9M

Select item 438371316.

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes

Jean-Philippe Lambert, Monika Tucholska, Christopher Go, James D.R. Knight, Anne-Claude Gingras

J Proteomics. Author manuscript; available in PMC 2016 Apr 6.

Published in final edited form as: J Proteomics. 2015 Apr 6; 118: 81–94. Published online 2014 Oct 2. doi: 10.1016/j.jprot.2014.09.011

PMCID:: PMC4383713

Article PDF–1.4M

Select item 979798817.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Article PDF–6.9M

Select item 905883618.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Article PDF–2.9M

Select item 659455119.

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin

Cell Rep. Author manuscript; available in PMC 2019 Jun 26.

Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060

PMCID:: PMC6594551

Article PDF–1.4M

Select item 426658820.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Article PDF–3.1M

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