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Select item 76733271.

High expression of CIN85 promotes proliferation and invasion of human esophageal squamous cell carcinoma

Xiao-Yang Hua, Xing-Xing Bie, Xi Cheng, Shu-Guang Zhang

Mol Med Rep. 2021 Jan; 23(1): 12. Published online 2020 Nov 3. doi: 10.3892/mmr.2020.11650

PMCID:: PMC7673327

Article PDF–1.1M

Select item 42680552.

Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis

Gulzar Ahmad, Bhopal Mohapatra, Nancy A. Schulte, Scott Nadeau, Haitao Luan, Neha Zutshi, Eric Tom, Cesar Ortega-Cava, Chun Tu, Masashi Sanada, Seishi Ogawa, Myron L. Toews, Vimla Band, Hamid Band

Int J Biochem Cell Biol. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Int J Biochem Cell Biol. 2014 Dec; 0: 123–134. Published online 2014 Oct 23. doi: 10.1016/j.biocel.2014.10.019

PMCID:: PMC4268055

Article PDF–2.9M

Select item 29503283.

A Critical Role of c-Cbl-Interacting Protein of 85 kDa in the Development and Progression of Head and Neck Squamous Cell Carcinomas through the Ras-ERK Pathway

Takahiro Wakasaki, Muneyuki Masuda, Hiroaki Niiro, Siamak Jabbarzadeh-Tabrizi, Kumiko Noda, Tadayoshi Taniyama, Shizuo Komune, Koichi Akashi

Neoplasia. 2010 Oct; 12(10): 789–796. doi: 10.1593/neo.10396

PMCID:: PMC2950328

Article PDF–1.7M

Select item 79051664.

SH3KBP1 Promotes Glioblastoma Tumorigenesis by Activating EGFR Signaling

Hai Song, Yanpei Wang, Chaojia Shi, Jianxiang Lu, Tian Yuan, Xiangpeng Wang

Front Oncol. 2020; 10: 583984. Published online 2021 Feb 11. doi: 10.3389/fonc.2020.583984

PMCID:: PMC7905166

Article PDF–3.2M

Select item 78257885.

In Silico Identification of Potential Druggable Binding Sites on CIN85 SH3 Domain

Serena Vittorio, Thomas Seidel, Arthur Garon, Rosaria Gitto, Thierry Langer, Laura De Luca

Int J Mol Sci. 2021 Jan; 22(2): 534. Published online 2021 Jan 7. doi: 10.3390/ijms22020534

PMCID:: PMC7825788

Article PDF–4.6M

Select item 59402576.

Germline deletion of CIN85 in humans with X chromosome–linked antibody deficiency

Baerbel Keller, Moneef Shoukier, Kathrin Schulz, Arshiya Bhatt, Ines Heine, Valentina Strohmeier, Carsten Speckmann, Niklas Engels, Klaus Warnatz, Jürgen Wienands

J Exp Med. 2018 May 7; 215(5): 1327–1336. doi: 10.1084/jem.20170534

PMCID:: PMC5940257

Article PDF–1.5M

Select item 50161337.

A Novel Interaction of the Catalytic Subunit of Protein Phosphatase 2A with the Adaptor Protein CIN85 Suppresses Phosphatase Activity and Facilitates Platelet Outside-in α_IIbβ₃ Integrin Signaling

Tanvir Khatlani, Subhashree Pradhan, Qi Da, Tanner Shaw, Vladimir L. Buchman, Miguel A. Cruz, K. Vinod Vijayan

J Biol Chem. 2016 Aug 12; 291(33): 17360–17368. Published online 2016 Jun 22. doi: 10.1074/jbc.M115.704296

PMCID:: PMC5016133

Article PDF–2.4M

Select item 28494938.

The ORF3 Protein of Hepatitis E Virus Delays Degradation of Activated Growth Factor Receptors by Interacting with CIN85 and Blocking Formation of the Cbl-CIN85 Complex

Vivek Chandra, Manjula Kalia, Krishnan Hajela, Shahid Jameel

J Virol. 2010 Apr; 84(8): 3857–3867. Published online 2010 Feb 3. doi: 10.1128/JVI.01994-09

PMCID:: PMC2849493

Article PDF–1.6M

Select item 77015729.

LncRNA ARAP1‐AS2 promotes high glucose‐induced human proximal tubular cell injury via persistent transactivation of the EGFR by interacting with ARAP1

Xin Li, Tian‐Kui Ma, Si Wen, Lu‐Lu Li, Li Xu, Xin‐Wang Zhu, Cong‐Xiao Zhang, Nan Liu, Xu Wang, Qiu‐Ling Fan

J Cell Mol Med. 2020 Nov; 24(22): 12994–13009. Published online 2020 Sep 23. doi: 10.1111/jcmm.15897

PMCID:: PMC7701572

Article PDF–2.7M

Select item 377064410.

Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications

Jose L. Ortega Roldan, Salvador Casares, Malene Ringkjøbing Jensen, Nayra Cárdenes, Jerónimo Bravo, Martin Blackledge, Ana I. Azuaga, Nico A. J. van Nuland

PLoS One. 2013; 8(9): e73018. Published online 2013 Sep 11. doi: 10.1371/journal.pone.0073018

PMCID:: PMC3770644

Article PDF–3.0M

Select item 308317511.

CIN85 Modulates the Down-regulation of FcγRIIa Expression and Function by c-Cbl in a PKC-dependent Manner in Human Neutrophils

Louis Marois, Myriam Vaillancourt, Guillaume Paré, Valérie Gagné, Maria J. G. Fernandes, Emmanuelle Rollet-Labelle, Paul H. Naccache

J Biol Chem. 2011 Apr 29; 286(17): 15073–15084. Published online 2011 Mar 3. doi: 10.1074/jbc.M110.213660

PMCID:: PMC3083175

Article PDF–3.0M

Select item 55629912.

Herpes simplex virus 1 infected cell protein 0 forms a complex with CIN85 and Cbl and mediates the degradation of EGF receptor from cell surfaces

Yu Liang, Alexei Kurakin, Bernard Roizman

Proc Natl Acad Sci U S A. 2005 Apr 19; 102(16): 5838–5843. Published online 2005 Apr 11. doi: 10.1073/pnas.0501253102

PMCID:: PMC556299

Article PDF–591K

Select item 16447613.

Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization

Mirko H. H. Schmidt, Frank B. Furnari, Webster K. Cavenee, Oliver Bögler

Proc Natl Acad Sci U S A. 2003 May 27; 100(11): 6505–6510. Published online 2003 May 6. doi: 10.1073/pnas.1031790100

PMCID:: PMC164476

Article PDF–264K

Select item 450889614.

CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface

Ihor Yakymovych, Mariya Yakymovych, Guangxiang Zang, Yabing Mu, Anders Bergh, Maréne Landström, Carl-Henrik Heldin

J Cell Biol. 2015 Jul 20; 210(2): 319–332. doi: 10.1083/jcb.201411025

PMCID:: PMC4508896

Article PDF–2.8M

Select item 294406515.

A Dyn2–CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding

Barbara Schroeder, Shaun G Weller, Jing Chen, Daniel Billadeau, Mark A McNiven

EMBO J. 2010 Sep 15; 29(18): 3039–3053. Published online 2010 Aug 13. doi: 10.1038/emboj.2010.190

PMCID:: PMC2944065

Article PDF–3.3M

Select item 765715916.

Adaptor protein complex of FRS2β and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation

Yuriko Minegishi, Yoshio Shibagaki, Anna Mizutani, Koji Fujita, Tohru Tezuka, Masao Kinoshita, Masahiko Kuroda, Seisuke Hattori, Noriko Gotoh

Cancer Sci. 2013 Mar; 104(3): 345–352. Published online 2013 Feb 8. doi: 10.1111/cas.12086

PMCID:: PMC7657159

Article PDF–1.6M

Select item 380558317.

Inhibition of CIN85-Mediated Invasion by a Novel SH3 Domain Binding Motif in the Lysyl Oxidase Propeptide

Seiichi Sato, Yingshe Zhao, Misa Imai, Philip C. Simister, Stephan M. Feller, Philip C. Trackman, Kathrin H. Kirsch, Gail E. Sonenshein

PLoS One. 2013; 8(10): e77288. Published online 2013 Oct 22. doi: 10.1371/journal.pone.0077288

PMCID:: PMC3805583

Article PDF–4.6M

Select item 344240818.

CIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies

Barbara Schroeder, Subhashini Srivatsan, Andrey Shaw, Daniel Billadeau, Mark A. McNiven

Mol Biol Cell. 2012 Sep 15; 23(18): 3602–3611. doi: 10.1091/mbc.E11-08-0666

PMCID:: PMC3442408

Article PDF–1.3M

Select item 144042119.

State and Role of Src Family Kinases in Replication of Herpes Simplex Virus 1

Yu Liang, Bernard Roizman

J Virol. 2006 Apr; 80(7): 3349–3359. doi: 10.1128/JVI.80.7.3349-3359.2006

PMCID:: PMC1440421

Article PDF–470K

Select item 30660820.

Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein

Ivan Gout, Gayle Middleton, Jimi Adu, Natalia N. Ninkina, Ludmila B. Drobot, Valery Filonenko, Gennady Matsuka, Alun M. Davies, Michael Waterfield, Vladimir L. Buchman

EMBO J. 2000 Aug 1; 19(15): 4015–4025. doi: 10.1093/emboj/19.15.4015