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Items: 1 to 20 of 32

1.
G-protein activation by a metabotropic glutamate receptor
Alpay B. Seven, Ximena Barros-Álvarez, Marine de Lapeyrière, Makaía M. Papasergi-Scott, Michael J. Robertson, Chensong Zhang, Robert M. Nwokonko, Yang Gao, Justin G. Meyerowitz, Jean-Philippe Rocher, Dominik Schelshorn, Brian K. Kobilka, Jesper M. Mathiesen, Georgios Skiniotis
Nature. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Nature. 2021 Jul; 595(7867): 450–454. Published online 2021 Jun 30. doi: 10.1038/s41586-021-03680-3
PMCID:
PMC8822903
AbstractArticlePDF–5.5M
2.
Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state
Anne-Marinette Cao, Robert B. Quast, Fataneh Fatemi, Philippe Rondard, Jean-Philippe Pin, Emmanuel Margeat
Nat Commun. 2021; 12: 5426. Published online 2021 Sep 14. doi: 10.1038/s41467-021-25620-5
PMCID:
PMC8440590
AbstractArticlePDF–3.6M
3.
Conformational rearrangement during activation of a metabotropic glutamate receptor
Brandon Wey-Hung Liauw, Hamid Samareh Afsari, Reza Vafabakhsh
Nat Chem Biol. Author manuscript; available in PMC 2021 Jul 4.
Published in final edited form as: Nat Chem Biol. 2021 Mar; 17(3): 291–297. Published online 2021 Jan 4. doi: 10.1038/s41589-020-00702-5
PMCID:
PMC7904630
AbstractArticlePDF–5.1M
4.
Group II mGluRs suppress hyperexcitability in mouse and human nociceptors
Steve Davidson, Judith P. Golden, Bryan A. Copits, Pradipta R. Ray, Sherri K. Vogt, Manouela V. Valtcheva, Robert E. Schmidt, Andrea Ghetti, Theodore Price, Robert W. Gereau, IV
Pain. Author manuscript; available in PMC 2017 Sep 1.
Published in final edited form as: Pain. 2016 Sep; 157(9): 2081–2088. doi: 10.1097/j.pain.0000000000000621
PMCID:
PMC4988887
AbstractArticlePDF–1.7M
5.
Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ‐46281222
Maarten L J Doornbos, Laura Pérez‐Benito, Gary Tresadern, Thea Mulder‐Krieger, Ilse Biesmans, Andrés A Trabanco, Jose María Cid, Hilde Lavreysen, Adriaan P IJzerman, Laura H Heitman
Br J Pharmacol. 2016 Feb; 173(3): 588–600. Published online 2016 Jan 13. doi: 10.1111/bph.13390
PMCID:
PMC4728424
AbstractArticlePDF–1.5M
6.
Molecular determinants of positive allosteric modulation of the human metabotropic glutamate receptor 2
A Farinha, H Lavreysen, L Peeters, B Russo, S Masure, A A Trabanco, J Cid, G Tresadern
Br J Pharmacol. 2015 May; 172(9): 2383–2396. Published online 2015 Feb 27. doi: 10.1111/bph.13065
PMCID:
PMC4403101
AbstractArticlePDF–1.0M
7.
Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling
Driss El Moustaine, Sébastien Granier, Etienne Doumazane, Pauline Scholler, Rita Rahmeh, Patrick Bron, Bernard Mouillac, Jean-Louis Banères, Philippe Rondard, Jean-Philippe Pin
Proc Natl Acad Sci U S A. 2012 Oct 2; 109(40): 16342–16347. Published online 2012 Sep 17. doi: 10.1073/pnas.1205838109
PMCID:
PMC3479612
AbstractArticlePDF–905K
8.
Membrane-Sensitive Conformational States of Helix 8 in the Metabotropic Glu2 Receptor, a Class C GPCR
Agostino Bruno, Gabriele Costantino, Gianni de Fabritiis, Manuel Pastor, Jana Selent
PLoS One. 2012; 7(8): e42023. Published online 2012 Aug 1. doi: 10.1371/journal.pone.0042023
Correction in:
PLoS One. 2012; 7(11): 10.1371/annotation/b3d4540a-9b4b-4855-b570-6324b40232fe.
PMCID:
PMC3411606
AbstractArticlePDF–387K
9.
The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival
Hyoung-gon Lee, Xiongwei Zhu, Gemma Casadesus, Mercé Pallàs, Antoni Camins, Michael J. O’Neill, Shigetada Nakanishi, George Perry, Mark A. Smith
Brain Res. Author manuscript; available in PMC 2009 Jun 18.
Published in final edited form as: Brain Res. 2009 Jan 16; 1249: 244–250. Published online 2008 Nov 5. doi: 10.1016/j.brainres.2008.10.055
PMCID:
PMC2698437
AbstractArticlePDF–842K
10.
Heterodimerization of Chemoreceptors TAS1R3 and mGlu2 in Human Blood Leukocytes
Lena Ball, Julia Bauer, Dietmar Krautwurst
Int J Mol Sci. 2023 Aug; 24(16): 12942. Published online 2023 Aug 18. doi: 10.3390/ijms241612942
PMCID:
PMC10454557
AbstractArticlePDF–3.0M
11.
Rescue of Infralimbic mGluR2 Deficit Restores Control Over Drug-Seeking Behavior in Alcohol Dependence
Marcus W. Meinhardt, Anita C. Hansson, Stephanie Perreau-Lenz, Christina Bauder-Wenz, Oliver Stählin, Markus Heilig, Clive Harper, Karla U. Drescher, Rainer Spanagel, Wolfgang H. Sommer
J Neurosci. 2013 Feb 13; 33(7): 2794–2806. doi: 10.1523/JNEUROSCI.4062-12.2013
PMCID:
PMC3711176
AbstractArticlePDF–1.9M
12.
Elevated Level of Metabotropic Glutamate Receptor 2/3 in the Prefrontal Cortex in Major Depression
Anteneh M. Feyissa, William L. Woolverton, Jose J. Miguel-Hidalgo, Zhixia Wang, Patrick B. Kyle, Gregor Hasler, Craig A. Stockmeier, Abiye H. Iyo, Beata Karolewicz
Prog Neuropsychopharmacol Biol Psychiatry. Author manuscript; available in PMC 2011 Mar 17.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2010 Mar 17; 34(2): 279–283. Published online 2009 Nov 26. doi: 10.1016/j.pnpbp.2009.11.018
PMCID:
PMC2826512
AbstractArticlePDF–727K
13.
Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia
Subroto Ghose, Jeremy M. Crook, Cynthia L. Bartus, Thomas G. Sherman, Mary M. Herman, Thomas M. Hyde, Joel E. Kleinman, Mayada Akil
Int J Neurosci. Author manuscript; available in PMC 2009 Nov 1.
Published in final edited form as: Int J Neurosci. 2008 Nov; 118(11): 1609–1627. doi: 10.1080/00207450802330702
PMCID:
PMC2749493
AbstractArticlePDF–1.1M
14.
Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease
Yuesong Gong, Carol F. Lippa, Jinghua Zhu, Qishan Lin, Andrea L. Rosso
Brain Res. Author manuscript; available in PMC 2009 Sep 25.
Published in final edited form as: Brain Res. 2009 Oct 6; 1292: 191–198. Published online 2009 Jul 25. doi: 10.1016/j.brainres.2009.07.056
PMCID:
PMC2745956
AbstractArticlePDF–231K
15.
SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells
Jinliang Wang, Guan Yang, Xinxin Wang, Zhiyuan Wen, Lei Shuai, Jie Luo, Chong Wang, Ziruo Sun, Renqiang Liu, Jinying Ge, Xijun He, Ronghong Hua, Xijun Wang, Xiao Yang, Weiye Chen, Gongxun Zhong, Zhigao Bu
Cell Discov. 2021; 7: 119. Published online 2021 Dec 14. doi: 10.1038/s41421-021-00357-z
Correction in:
Cell Discov. 2021; 7: 124.
PMCID:
PMC8668938
AbstractArticlePDF–3.9M
16.
Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics
Natalie Matosin, Francesca Fernandez-Enright, Elisabeth Frank, Chao Deng, Jenny Wong, Xu-Feng Huang, Kelly A. Newell
J Psychiatry Neurosci. 2014 Nov; 39(6): 407–416. Prepublished online 2014 Jun 24. doi: 10.1503/jpn.130242
PMCID:
PMC4214875
AbstractArticlePDF–546K
17.
Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia
José L. Moreno, Patricia Miranda-Azpiazu, Aintzane García-Bea, Jason Younkin, Meng Cui, Alexey Kozlenkov, Ariel Ben-Ezra, Georgios Voloudakis, Amanda K. Fakira, Lia Baki, Yongchao Ge, Anastasios Georgakopoulos, José A. Morón, Graeme Milligan, Juan F. López-Giménez, Nikolaos K. Robakis, Diomedes E. Logothetis, J. Javier Meana, Javier González-Maeso
Sci Signal. Author manuscript; available in PMC 2017 Jan 12.
Published in final edited form as: Sci Signal. 2016; 9(410): ra5. Published online 2016 Jan 12. doi: 10.1126/scisignal.aab0467
PMCID:
PMC4819166
AbstractArticlePDF–1.0M
18.
Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function
José L. Moreno, Carolina Muguruza, Adrienne Umali, Steven Mortillo, Terrell Holloway, Fuencisla Pilar-Cuéllar, Giuseppe Mocci, Jeremy Seto, Luis F. Callado, Rachael L. Neve, Graeme Milligan, Stuart C. Sealfon, Juan F. López-Giménez, J. Javier Meana, Deanna L. Benson, Javier González-Maeso
J Biol Chem. 2012 Dec 28; 287(53): 44301–44319. Published online 2012 Nov 5. doi: 10.1074/jbc.M112.413161
PMCID:
PMC3531745
AbstractArticlePDF–3.3M
19.
Identification of a Novel Serotonin/Glutamate Receptor Complex Implicated in Psychosis
Javier González-Maeso, Rosalind Ang, Tony Yuen, Pokman Chan, Noelia V. Weisstaub, Juan F. López-Giménez, Mingming Zhou, Yuuya Okawa, Luis F. Callado, Graeme Milligan, Jay A. Gingrich, Marta Filizola, J. Javier Meana, Stuart C. Sealfon
Nature. Author manuscript; available in PMC 2009 Sep 14.
Published in final edited form as: Nature. 2008 Mar 6; 452(7183): 93–97. Published online 2008 Feb 24. doi: 10.1038/nature06612
PMCID:
PMC2743172
AbstractArticlePDF–1.2M
20.
Group II Metabotropic Glutamate Receptor Interactions with NHERF Scaffold Proteins: Implications for Receptor Localization in Brain
Stefanie L. Ritter-Makinson, Maryse Paquet, James W. Bogenpohl, Rachel E. Rodin, C. Chris Yun, Edward J. Weinman, Yoland Smith, Randy A. Hall
Neuroscience. Author manuscript; available in PMC 2018 Jun 14.
Published in final edited form as: Neuroscience. 2017 Jun 14; 353: 58–75. Published online 2017 Apr 7. doi: 10.1016/j.neuroscience.2017.03.060
PMCID:
PMC5503475
AbstractArticlePDF–1.0M

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