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Select item 57941861.

Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay

Olivier Duverger, Jenna C. Carlson, Chelsea M. Karacz, Mary E. Schwartz, Michael A. Cross, Mary L. Marazita, John R. Shaffer, Maria I. Morasso

PLoS Genet. 2018 Jan; 14(1): e1007168. Published online 2018 Jan 22. doi: 10.1371/journal.pgen.1007168

Correction in:: PLoS Genet. 2019 Jun; 15(6): e1008230.

PMCID:: PMC5794186

Article PDF–8.7M

Select item 90668662.

TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5

Xiaoying Jin, Dandan Wang, Mengxia Lei, Yan Guo, Yuqing Cui, Fengzhi Chen, Weiling Sun, Xuesong Chen

J Transl Med. 2022; 20: 191. Published online 2022 May 4. doi: 10.1186/s12967-022-03370-2

PMCID:: PMC9066866

Article PDF–6.8M

Select item 73102873.

FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1

Weidong Shi, Lanyun Feng, Shu Dong, Zhouyu Ning, Yongqiang Hua, Luming Liu, Zhen Chen, Zhiqiang Meng

Cell Commun Signal. 2020; 18: 100. Published online 2020 Jun 23. doi: 10.1186/s12964-020-00604-y

PMCID:: PMC7310287

Article PDF–2.2M

Select item 74526804.

N6-Methyladenosine modification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1

Chenliang Zhou, Zhichang Zhang, Xiaoshi Zhu, Guowei Qian, Yan Zhou, Yong Sun, Wenxi Yu, Jiahui Wang, Haiyang Lu, Feng Lin, Zan Shen, Shuier Zheng

EBioMedicine. 2020 Sep; 59: 102955. Published online 2020 Aug 24. doi: 10.1016/j.ebiom.2020.102955

PMCID:: PMC7452680

Article PDF–5.1M

Select item 69251345.

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers

Kyoungwha Pang, Jinah Park, Sung Gwe Ahn, Jihee Lee, Yuna Park, Akira Ooshima, Seiya Mizuno, Satoshi Yamashita, Kyung-Soon Park, So-Young Lee, Joon Jeong, Toshikazu Ushijima, Kyung-Min Yang, Seong-Jin Kim

Nat Commun. 2019; 10: 5805. Published online 2019 Dec 20. doi: 10.1038/s41467-019-13852-5

PMCID:: PMC6925134

Article PDF–4.5M

Select item 69620966.

Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F

Pauline Esteves, Laetitia Dard, Aurélia Brillac, Christophe Hubert, Saharnaz Sarlak, Benoît Rousseau, Elodie Dumon, Julien Izotte, Marc Bonneu, Didier Lacombe, Jean-William Dupuy, Nivea Amoedo, Rodrigue Rossignol

Oncogene. 2020; 39(3): 617–636. Published online 2019 Sep 16. doi: 10.1038/s41388-019-1009-x

PMCID:: PMC6962096

Article PDF–4.7M

Select item 20641777.

New consensus nomenclature for mammalian keratins

Jürgen Schweizer, Paul E. Bowden, Pierre A. Coulombe, Lutz Langbein, E. Birgitte Lane, Thomas M. Magin, Lois Maltais, M. Bishr Omary, David A.D. Parry, Michael A. Rogers, Mathew W. Wright

J Cell Biol. 2006 Jul 17; 174(2): 169–174. doi: 10.1083/jcb.200603161

PMCID:: PMC2064177

Article PDF–829K

Select item 48828678.

Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor

Sarah Daakour, Leon Juvenal Hajingabo, Despoina Kerselidou, Aurelie Devresse, Richard Kettmann, Nicolas Simonis, Franck Dequiedt, Jean-Claude Twizere

BMC Cancer. 2016; 16: 335. Published online 2016 May 26. doi: 10.1186/s12885-016-2374-2

PMCID:: PMC4882867

Article PDF–1.8M

Select item 93604439.

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner

Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas

Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3

PMCID:: PMC9360443

Article PDF–5.8M

Select item 267088110.

Charting the molecular network of the drug target Bcr-Abl

Marc Brehme, Oliver Hantschel, Jacques Colinge, Ines Kaupe, Melanie Planyavsky, Thomas Köcher, Karl Mechtler, Keiryn L. Bennett, Giulio Superti-Furga

Proc Natl Acad Sci U S A. 2009 May 5; 106(18): 7414–7419. Published online 2009 Apr 20. doi: 10.1073/pnas.0900653106

PMCID:: PMC2670881

Article PDF–813K

Select item 471456111.

KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II

Ryan P. McNamara, Jonathan E. Reeder, Elizabeth A. McMillan, Curtis W. Bacon, Jennifer L. McCann, Iván D’Orso

Mol Cell. Author manuscript; available in PMC 2017 Jan 7.

Published in final edited form as: Mol Cell. 2016 Jan 7; 61(1): 39–53. Published online 2015 Dec 24. doi: 10.1016/j.molcel.2015.11.004

PMCID:: PMC4714561

Article PDF–2.2M

Select item 1014884312.

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin

Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun

Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y

PMCID:: PMC10148843

Article PDF–11M

Select item 422778613.

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling

Rajat Roy, Danielle Durie, Hui Li, Bing-Qian Liu, John Mark Skehel, Francesco Mauri, Lucia Veronica Cuorvo, Mattia Barbareschi, Lin Guo, Martin Holcik, Michael J. Seckl, Olivier E. Pardo

Nucleic Acids Res. 2014 Nov 10; 42(20): 12483–12497. Published online 2014 Oct 16. doi: 10.1093/nar/gku953

PMCID:: PMC4227786

Article PDF–688K

Select item 526093914.

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman

Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387

PMCID:: PMC5260939

Article PDF–1.1M

Select item 673723015.

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant

Ana M. Matos, Francisco R. Pinto, Patrícia Barros, Margarida D. Amaral, Rainer Pepperkok, Paulo Matos

J Biol Chem. 2019 Sep 6; 294(36): 13396–13410. Published online 2019 Jul 19. doi: 10.1074/jbc.RA119.008738

PMCID:: PMC6737230

Article PDF–2.6M

Select item 573755516.

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality

Helen Hoffmeister, Andreas Fuchs, Fabian Erdel, Sophia Pinz, Regina Gröbner-Ferreira, Astrid Bruckmann, Rainer Deutzmann, Uwe Schwartz, Rodrigo Maldonado, Claudia Huber, Anne-Sarah Dendorfer, Karsten Rippe, Gernot Längst

Nucleic Acids Res. 2017 Oct 13; 45(18): 10534–10554. Published online 2017 Aug 28. doi: 10.1093/nar/gkx711

PMCID:: PMC5737555

Article PDF–7.2M

Select item 1003393717.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Article PDF–1.5M

Select item 944065318.

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy

Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui

Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y

PMCID:: PMC9440653

Article PDF–2.9M

Select item 338306519.

Mapping the Nephronophthisis-Joubert-Meckel-Gruber Protein Network Reveals Ciliopathy Disease Genes and Pathways

Liyun Sang, Julie J. Miller, Kevin C. Corbit, Rachel H. Giles, Matthew J. Brauer, Edgar A. Otto, Lisa M. Baye, Xiaohui Wen, Suzie J. Scales, Mandy Kwong, Erik G. Huntzicker, Mindan K. Sfakianos, Wendy Sandoval, J. Fernando Bazan, Priya Kulkarni, Francesc R. Garcia-Gonzalo, Allen D. Seol, John F. O'Toole, Susanne Held, Heiko M. Reutter, William S. Lane, Muhammad Arshad Rafiq, Abdul Noor, Muhammad Ansar, Akella Radha Rama Devi, Val C. Sheffield, Diane C. Slusarski, John B. Vincent, Daniel A. Doherty, Friedhelm Hildebrandt, Jeremy F. Reiter, Peter K. Jackson

Cell. Author manuscript; available in PMC 2012 Jun 26.

Published in final edited form as: Cell. 2011 May 13; 145(4): 513–528. doi: 10.1016/j.cell.2011.04.019

PMCID:: PMC3383065

Article PDF–2.0M

Select item 404523520.

Identifying biological pathways that underlie primordial short stature using network analysis

Dan Hanson, Adam Stevens, Philip G Murray, Graeme C M Black, Peter E Clayton

J Mol Endocrinol. 2014 Jun; 52(3): 333–344. Prepublished online 2014 Apr 7. doi: 10.1530/JME-14-0029

PMCID:: PMC4045235

Article PDF–663K

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