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Select item 70940261.

Antibodies that conformationally activate ADAMTS13 allosterically enhance metalloprotease domain function

An-Sofie Schelpe, Anastasis Petri, Elien Roose, Inge Pareyn, Hans Deckmyn, Simon F. De Meyer, James T. B. Crawley, Karen Vanhoorelbeke

Blood Adv. 2020 Mar 24; 4(6): 1072–1080. Published online 2020 Mar 20. doi: 10.1182/bloodadvances.2019001375

PMCID:: PMC7094026

Article PDF–1.2M

Select item 67099912.

Formation and Resolution of Pial Microvascular Thrombosis in a Mouse Model of Thrombotic Thrombocytopenic Purpura

Reheman Adili, Michael Holinstat

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Sep; 39(9): 1817–1830. Published online 2019 Jul 25. doi: 10.1161/ATVBAHA.119.312848

PMCID:: PMC6709991

Article PDF–2.9M

Select item 62146163.

Transfusion of platelets loaded with recombinant ADAMTS13 is efficacious for inhibiting arterial thrombosis in mice and in human

Mohammad S. Abdelgawwad, Wenjing Cao, Liang Zheng, Nicole K. Kocher, Lance A. Williams, X. Long Zheng

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Nov; 38(11): 2731–2743. doi: 10.1161/ATVBAHA.118.311407

PMCID:: PMC6214616

Article PDF–1.9M

Select item 49688304.

Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura

Louis Deforche, Claudia Tersteeg, Elien Roose, Aline Vandenbulcke, Nele Vandeputte, Inge Pareyn, Elien De Cock, Hanspeter Rottensteiner, Hans Deckmyn, Simon F. De Meyer, Karen Vanhoorelbeke

PLoS One. 2016; 11(8): e0160388. Published online 2016 Aug 1. doi: 10.1371/journal.pone.0160388

PMCID:: PMC4968830

Article PDF–2.6M

Select item 44408845.

Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models

Brandy Pickens, Yingying Mao, Dengju Li, Don L. Siegel, Mortimer Poncz, Douglas B. Cines, X. Long Zheng

Blood. 2015 May 21; 125(21): 3326–3334. Prepublished online 2015 Mar 23. doi: 10.1182/blood-2014-07-587139

PMCID:: PMC4440884

Article

Select item 36507046.

AAV-mediated expression of an ADAMTS13 variant prevents shigatoxin-induced thrombotic thrombocytopenic purpura

Sheng-Yu Jin, Juan Xiao, Jialing Bao, Shangzhen Zhou, J. Fraser Wright, X. Long Zheng

Blood. 2013 May 9; 121(19): 3825–3829. Prepublished online 2013 Mar 20. doi: 10.1182/blood-2013-02-486779

PMCID:: PMC3650704

Article

Select item 29814857.

Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice

Jing Huang, David G. Motto, David R. Bundle, J. Evan Sadler

Blood. 2010 Nov 4; 116(18): 3653–3659. Prepublished online 2010 Jul 19. doi: 10.1182/blood-2010-02-271957

PMCID:: PMC2981485

Article

Select item 26523658.

Correction of murine ADAMTS13 deficiency by hematopoietic progenitor cell–mediated gene therapy

Pablo Laje, Dezhi Shang, Wenjing Cao, Masami Niiya, Masayuki Endo, Antoneta Radu, Nicole DeRogatis, Friedrich Scheiflinger, Philip W. Zoltick, Alan W. Flake, X. Long Zheng

Blood. 2009 Mar 5; 113(10): 2172–2180. Prepublished online 2009 Jan 13. doi: 10.1182/blood-2008-08-173021

PMCID:: PMC2652365

Article

Select item 25739959.

ADAMTS13 is expressed in hepatic stellate cells

Wenhua Zhou, Mari Inada, Tai-Ping Lee, Daniel Benten, Sergey Lyubsky, Eric E Bouhassira, Sanjeev Gupta, Han-Mou Tsai

Lab Invest. Author manuscript; available in PMC 2008 Oct 28.

Published in final edited form as: Lab Invest. 2005 Jun; 85(6): 780–788. doi: 10.1038/labinvest.3700275

PMCID:: PMC2573995

Article PDF–1.0M

Select item 192477410.

An IAP retrotransposon in the mouse ADAMTS13 gene creates ADAMTS13 variant proteins that are less effective in cleaving von Willebrand factor multimers

Wenhua Zhou, Eric E. Bouhassira, Han-Mou Tsai

Blood. 2007 Aug 1; 110(3): 886–893. Prepublished online 2007 Apr 10. doi: 10.1182/blood-2007-01-070953

PMCID:: PMC1924774

Article

Select item 881001811.

ADAMTS-13-regulated nuclear factor E2-related factor 2 signaling inhibits ferroptosis to ameliorate cisplatin-induced acute kidney injuy: Running title: Role of ADAMTS-13 and ferroptosis in AKI.

Xiaoyan Meng, Wenjing Huang, Weiwei Mo, Tingting Shu, Haoqiang Yang, Haibo Ning

Bioengineered. 2021; 12(2): 11610–11621. Published online 2021 Dec 7. doi: 10.1080/21655979.2021.1994707

PMCID:: PMC8810018

Article PDF–3.4M

Select item 676426612.

Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy

Liang Zheng, Di Zhang, Wenjing Cao, Wen-Chao Song, X. Long Zheng

Blood. 2019 Sep 26; 134(13): 1095–1105. Prepublished online 2019 Aug 13. doi: 10.1182/blood.2019001040

PMCID:: PMC6764266

Article

Select item 612808213.

von Willebrand factor enhances microvesicle-induced vascular leakage and coagulopathy in mice with traumatic brain injury

Yingang Wu, Wei Liu, Yuan Zhou, Tristan Hilton, Zilong Zhao, Wei Liu, Min Wang, Jason Yeon, Katie Houck, Perumal Thiagarajan, Fangyi Zhang, Fu-Dong Shi, Xiaoping Wu, Min Li, Jing-fei Dong, Jianning Zhang

Blood. 2018 Sep 6; 132(10): 1075–1084. Prepublished online 2018 Jun 25. doi: 10.1182/blood-2018-03-841932

PMCID:: PMC6128082

Article

Select item 605561214.

Role of von Willebrand factor and ADAMTS‐13 in early brain injury after experimental subarachnoid hemorrhage

H. Wan, Y. Wang, J. Ai, S. Brathwaite, H. Ni, R.L. Macdonald, E.M. Hol, J.C.M. Meijers, M.D.I. Vergouwen

J Thromb Haemost. 2018 Jul; 16(7): 1413–1422. Published online 2018 Jun 8. doi: 10.1111/jth.14136

PMCID:: PMC6055612

Article PDF–657K

Select item 550128715.

ADAMTS13 retards progression of diabetic nephropathy by inhibiting intrarenal thrombosis in mice

Nirav Dhanesha, Prakash Doddapattar, Mehul R Chorawala, Manasa K. Nayak, Koichi Kokame, Janice M. Staber, Steven R. Lentz, Anil K. Chauhan

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Jul; 37(7): 1332–1338. Published online 2017 May 11. doi: 10.1161/ATVBAHA.117.309539

PMCID:: PMC5501287

Article PDF–661K

Select item 550114716.

ADAMTS13 controls vascular remodeling by modifying VWF reactivity during stroke recovery

Haochen Xu, Yongliang Cao, Xing Yang, Ping Cai, Lijing Kang, Ximin Zhu, Haiyu Luo, Lu Lu, Lixiang Wei, Xiaofei Bai, Yuanbo Zhu, Bing-Qiao Zhao, Wenying Fan

Blood. 2017 Jul 6; 130(1): 11–22. Prepublished online 2017 Apr 20. doi: 10.1182/blood-2016-10-747089

PMCID:: PMC5501147

Article

Select item 500189517.

Endothelial cell-derived VWF is the major determinant that mediates VWF-dependent acute ischemic stroke by promoting post-ischemic thrombo-inflammation

Nirav Dhanesha, Prem Prakash, Prakash Doddapattar, Ira Khanna, Molly J Pollpeter, Manasa K. Nayak, Janice M. Staber, Anil K. Chauhan

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Sep; 36(9): 1829–1837. Published online 2016 Jul 21. doi: 10.1161/ATVBAHA.116.307660

PMCID:: PMC5001895

Article PDF–2.7M

Select item 443201018.

von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans

Alexander T. Bauer, Jan Suckau, Kathrin Frank, Anna Desch, Lukas Goertz, Andreas H. Wagner, Markus Hecker, Tobias Goerge, Ludmila Umansky, Philipp Beckhove, Jochen Utikal, Christian Gorzelanny, Nancy Diaz-Valdes, Viktor Umansky, Stefan W. Schneider

Blood. 2015 May 14; 125(20): 3153–3163. Prepublished online 2015 Feb 24. doi: 10.1182/blood-2014-08-595686