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Select item 77691751.

Purinergic signaling is enhanced in the absence of UT‐A1 and UT‐A3

Nathaniel J. Himmel, Richard T. Rogers, Sara K. Redd, Yirong Wang, Mitsi A. Blount

Physiol Rep. 2021 Jan; 9(1): e14636. Published online 2020 Dec 28. doi: 10.14814/phy2.14636

PMCID:: PMC7769175

Article PDF–744K

Select item 73801882.

The urea transporter UT-A1 plays a predominant role in a urea-dependent urine-concentrating mechanism

Xiaoqiang Geng, Shun Zhang, Jinzhao He, Ang Ma, Yingjie Li, Min Li, Hong Zhou, Guangping Chen, Baoxue Yang

J Biol Chem. 2020 Jul 17; 295(29): 9893–9900. Published online 2020 May 27. doi: 10.1074/jbc.RA120.013628

PMCID:: PMC7380188

Article PDF–2.0M

Select item 72943403.

UT-A1/A3 knockout mice show reduced fibrosis following unilateral ureteral obstruction

Fitra Rianto, Akihiro Kuma, Carla L. Ellis, Faten Hassounah, Eva L. Rodriguez, Xiaonan H. Wang, Jeff M. Sands, Janet D. Klein

Am J Physiol Renal Physiol. 2020 May 1; 318(5): F1160–F1166. Published online 2020 Mar 16. doi: 10.1152/ajprenal.00008.2020

PMCID:: PMC7294340

Article

Select item 64593084.

Lack of urea transporters, UT-A1 and UT-A3, increases nitric oxide accumulation to dampen medullary sodium reabsorption through ENaC

Richard T. Rogers, Michael A. Sun, Qiang Yue, Hui-Fang Bao, Jeff M. Sands, Mitsi A. Blount, Douglas C. Eaton

Am J Physiol Renal Physiol. 2019 Mar 1; 316(3): F539–F549. Published online 2018 Dec 12. doi: 10.1152/ajprenal.00166.2018

PMCID:: PMC6459308

Article

Select item 35436215.

Urine concentration in the diabetic mouse requires both urea and water transporters

Titilayo O. Ilori, Mitsi A. Blount, Christopher F. Martin, Jeff M. Sands, Janet D. Klein

Am J Physiol Renal Physiol. 2013 Jan 1; 304(1): F103–F111. Published online 2012 Nov 7. doi: 10.1152/ajprenal.00385.2012

PMCID:: PMC3543621

Article

Select item 26143796.

Magnetic resonance imaging of urea transporter knockout mice reveals two distinct types of renal pelvic abnormality

Vinitha Jacob, Calista Harbaugh, John R. Dietz, Robert A. Fenton, Soo Mi Kim, Hayo Castrop, Jurgen Schnermann, Mark A. Knepper, Chung-Lin Chou, Stasia A. Anderson

Kidney Int. Author manuscript; available in PMC 2009 Nov 1.

Published in final edited form as: Kidney Int. 2008 Nov; 74(9): 1202–1208. Published online 2008 Aug 13. doi: 10.1038/ki.2008.392

PMCID:: PMC2614379

Article PDF–1.7M

Select item 14356877.

The UT-A Urea Transporter Promoter, UT-Aα, Targets Principal Cells of the Renal Inner Medullary Collecting Duct

Robert A. Fenton, Adetola Shodeinde, Mark A. Knepper

Am J Physiol Renal Physiol. Author manuscript; available in PMC 2007 Jan 1.

Published in final edited form as: Am J Physiol Renal Physiol. 2006 Jan; 290(1): F188–F195. Published online 2005 Aug 9. doi: 10.1152/ajprenal.00285.2005

PMCID:: PMC1435687

Article PDF–1.2M

Select item 14356868.

Renal Phenotype of UT-A Urea Transporter Knockout Mice

Robert A. Fenton, Anneliese Flynn, Adetola Shodeinde, Craig P. Smith, Jurgen Schnermann, Mark A. Knepper

J Am Soc Nephrol. Author manuscript; available in PMC 2006 Jun 1.

Published in final edited form as: J Am Soc Nephrol. 2005 Jun; 16(6): 1583–1592. Published online 2005 Apr 13. doi: 10.1681/ASN.2005010031

PMCID:: PMC1435686

Article PDF–478K

Select item 11902309.

Impaired Urea Accumulation in the Inner Medulla of Mice Lacking the Urea Transporter UT-A2

Shinichi Uchida, Eisei Sohara, Tatemitsu Rai, Masahito Ikawa, Masaru Okabe, Sei Sasaki

Mol Cell Biol. 2005 Aug; 25(16): 7357–7363. doi: 10.1128/MCB.25.16.7357-7363.2005

PMCID:: PMC1190230

Article PDF–252K

Select item 40994210.

Urinary concentrating defect in mice with selective deletion of phloretin-sensitive urea transporters in the renal collecting duct

Robert A. Fenton, Chung-Lin Chou, Gavin S. Stewart, Craig P. Smith, Mark A. Knepper

Proc Natl Acad Sci U S A. 2004 May 11; 101(19): 7469–7474. Published online 2004 May 3. doi: 10.1073/pnas.0401704101

PMCID:: PMC409942

Article PDF–475K

Select item 743800211.

Water transport mediated by murine urea transporters: implications for urine concentration mechanisms

J. Kabutomori, N. Pina-Lopes, R. Musa-Aziz

Biol Open. 2020 Aug 15; 9(8): bio051805. Published online 2020 Aug 14. doi: 10.1242/bio.051805

PMCID:: PMC7438002

Article PDF–1.1M

Select item 542371612.

Generation and phenotypic analysis of mice lacking all urea transporters

Tao Jiang, Yingjie Li, Anita T. Layton, Weiling Wang, Yi Sun, Min Li, Hong Zhou, Baoxue Yang

Kidney Int. Author manuscript; available in PMC 2017 May 9.

Published in final edited form as: Kidney Int. 2017 Feb; 91(2): 338–351. Published online 2016 Nov 30. doi: 10.1016/j.kint.2016.09.017

PMCID:: PMC5423716

Article PDF–1.0M

Select item 484981313.

Transgenic Restoration of Urea Transporter A1 Confers Maximal Urinary Concentration in the Absence of Urea Transporter A3

Janet D. Klein, Yanhua Wang, Abinash Mistry, Lauren M. LaRocque, Patrick A. Molina, Richard T. Rogers, Mitsi A. Blount, Jeff M. Sands

J Am Soc Nephrol. 2016 May; 27(5): 1448–1455. Published online 2015 Sep 25. doi: 10.1681/ASN.2014121267

PMCID:: PMC4849813

Article

Select item 323386414.

Role of thin descending limb urea transport in renal urea handling and the urine concentrating mechanism

Tianluo Lei, Lei Zhou, Anita T. Layton, Hong Zhou, Xuejian Zhao, Lise Bankir, Baoxue Yang

Am J Physiol Renal Physiol. 2011 Dec; 301(6): F1251–F1259. Published online 2011 Aug 17. doi: 10.1152/ajprenal.00404.2011

PMCID:: PMC3233864

Article

Select item 481111815.

Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy

Dongjun Lee, Ying-Hua Wang, Demetrios Kalaitzidis, Janani Ramachandran, Homare Eda, David B. Sykes, Noopur Raje, David T. Scadden

J Clin Invest. 2016 Apr 1; 126(4): 1300–1310. Published online 2016 Feb 29. doi: 10.1172/JCI84620

PMCID:: PMC4811118

Article PDF–1.7M

Select item 582758916.

GRHL2 Is Required for Collecting Duct Epithelial Barrier Function and Renal Osmoregulation

Christian Hinze, Janett Ruffert, Katharina Walentin, Nina Himmerkus, Elham Nikpey, Olav Tenstad, Helge Wiig, Kerim Mutig, Zeliha Yesim Yurtdas, Janet D. Klein, Jeff M. Sands, Federica Branchi, Michael Schumann, Sebastian Bachmann, Markus Bleich, Kai M. Schmidt-Ott

J Am Soc Nephrol. 2018 Mar; 29(3): 857–868. Published online 2017 Dec 13. doi: 10.1681/ASN.2017030353

PMCID:: PMC5827589

Article

Select item 363114017.

CBAP Functions as a Novel Component in Chemokine-Induced ZAP70-Mediated T-Cell Adhesion and Migration

Yun-Jung Chiang, Kun-Chin Ho, Chien-Tsang Sun, Jeng-Jiann Chiu, Fang-Jen Lee, Fang Liao, Hsin-Fang Yang-Yen, Jeffrey Jong-Young Yen

PLoS One. 2013; 8(4): e61761. Published online 2013 Apr 19. doi: 10.1371/journal.pone.0061761

PMCID:: PMC3631140

Article PDF–2.9M

Select item 263408518.

The European Renal Genome Project: An Integrated Approach Towards Understanding the Genetics of Kidney Development and Disease

TE Willnow, C Antignac, AW Brändli, EI Christensen, RD Cox, D Davidson, JA Davies, O Devuyst, G Eichele, ND Hastie, PJ Verroust, A Schedl, IC Meij

Organogenesis. 2005 Apr-Jun; 2(2): 42–47. doi: 10.4161/org.2.2.2118

PMCID:: PMC2634085

Article PDF–629K

Select item 248143119.

Identification of transcripts with enriched expression in the developing and adult pancreas

Brad G Hoffman, Bogard Zavaglia, Joy Witzsche, Teresa Ruiz de Algara, Mike Beach, Pamela A Hoodless, Steven JM Jones, Marco A Marra, Cheryl D Helgason

Genome Biol. 2008; 9(6): R99. Published online 2008 Jun 14. doi: 10.1186/gb-2008-9-6-r99