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Select item 84184651.

PHD finger protein 19 expression in multiple myeloma: Association with clinical features, induction therapy outcome, disease progression, and survival

Yaqiong Li, Jichang Gong, Lingli Zhang

J Clin Lab Anal. 2021 Sep; 35(9): e23910. Published online 2021 Aug 13. doi: 10.1002/jcla.23910

PMCID:: PMC8418465

Article PDF–823K

Select item 83162742.

PHF19 inhibition as a therapeutic target in Multiple Myeloma

Carolina D. Schinke, Jordan T. Bird, Pingping Qu, Shmuel Yaccoby, Valeriy V Lyzogubov, Randal Shelton, Wen Ling, Eileen M Boyle, Sharyu Deshpande, Stephanie D. Byrum, Charity Washam, Samuel Mackintosh, Owen Stephens, Sharmilan Thanendrarajan, Maurizio Zangari, John Shaughnessy, Jr, Fenghuang Zhan, Bart Barlogie, Frits van Rhee, Brian A Walker

Curr Res Transl Med. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Curr Res Transl Med. 2021 Jul; 69(3): 103290. Published online 2021 Apr 22. doi: 10.1016/j.retram.2021.103290

PMCID:: PMC8316274

Article PDF–1.0M

Select item 73266993.

Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease

Mike J. Mason, Carolina Schinke, Christine L. P. Eng, Fadi Towfic, Fred Gruber, Andrew Dervan, Brian S. White, Aditya Pratapa, Yuanfang Guan, Hongjie Chen, Yi Cui, Bailiang Li, Thomas Yu, Elias Chaibub Neto, Konstantinos Mavrommatis, Maria Ortiz, Valeriy Lyzogubov, Kamlesh Bisht, Hongyue Y. Dai, Frank Schmitz, Erin Flynt, Dan Rozelle, Samuel A. Danziger, Alexander Ratushny, Multiple Myeloma DREAM Consortium, William S. Dalton, Hartmut Goldschmidt, Herve Avet-Loiseau, Mehmet Samur, Boris Hayete, Pieter Sonneveld, Kenneth H. Shain, Nikhil Munshi, Daniel Auclair, Dirk Hose, Gareth Morgan, Matthew Trotter, Douglas Bassett, Jonathan Goke, Brian A. Walker, Anjan Thakurta, Justin Guinney

Leukemia. 2020; 34(7): 1866–1874. Published online 2020 Feb 14. doi: 10.1038/s41375-020-0742-z

PMCID:: PMC7326699

Article PDF–1.2M

Select item 103874914.

Regulation of hPCL3 isoforms’ ubiquitination by TRIM21 in non-small cell lung cancer progression

Ye Xu, Wenhong Liu, Xiawei Jiang, Junfeng Li, Qingling Liu, Fang Su, Shanming Ruan, Zhiqian Zhang, Fangfang Tao

Life Sci Alliance. 2023 Oct; 6(10): e202302060. Published online 2023 Jul 28. doi: 10.26508/lsa.202302060

PMCID:: PMC10387491

Article PDF–3.3M

Select item 70643375.

PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells

Payal Jain, Cecilia Ballare, Enrique Blanco, Pedro Vizan, Luciano Di Croce

eLife. 2020; 9: e51373. Published online 2020 Mar 10. doi: 10.7554/eLife.51373

PMCID:: PMC7064337

Article PDF–3.1M

Select item 67767956.

PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation

Zhihong Ren, Jeong Hyun Ahn, Hequn Liu, Yi-Hsuan Tsai, Natarajan V. Bhanu, Brian Koss, David F. Allison, Anqi Ma, Aaron J. Storey, Ping Wang, Samuel G. Mackintosh, Ricky D. Edmondson, Richard W. J. Groen, Anton C. Martens, Benjamin A. Garcia, Alan J. Tackett, Jian Jin, Ling Cai, Deyou Zheng, Gang Greg Wang

Blood. 2019 Oct 3; 134(14): 1176–1189. Prepublished online 2019 Aug 5. doi: 10.1182/blood.2019000578

PMCID:: PMC6776795

Article

Select item 81708197.

LINC_00355 promotes gastric cancer progression by upregulating PHF19 expression through sponging miR-15a-5p

Jishui Zhang, Wenhao Lv, Yagang Liu, Weihua Fu, Baosheng Chen, Qiutong Ma, Xin Gao

BMC Cancer. 2021; 21: 657. Published online 2021 Jun 2. doi: 10.1186/s12885-021-08227-3

PMCID:: PMC8170819

Article PDF–4.9M

Select item 61891448.

PHF19 promotes the proliferation, migration, and chemosensitivity of glioblastoma to doxorubicin through modulation of the SIAH1/β–catenin axis

Qing Deng, Jianbing Hou, Liying Feng, Ailing Lv, Xiaoxue Ke, Hanghua Liang, Feng Wang, Kui Zhang, Kuijun Chen, Hongjuan Cui

Cell Death Dis. 2018 Nov; 9(11): 1049. Published online 2018 Oct 15. doi: 10.1038/s41419-018-1082-z

PMCID:: PMC6189144

Article PDF–2.9M

Select item 46853179.

G9a orchestrates PCL3 and KDM7A to promote histone H3K27 methylation

Mei-Ren Pan, Ming-Chuan Hsu, Li-Tzong Chen, Wen-Chun Hung

Sci Rep. 2015; 5: 18709. Published online 2015 Dec 21. doi: 10.1038/srep18709

PMCID:: PMC4685317

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Select item 332303910.

Hypermethylated in Cancer 1 (HIC1) Recruits Polycomb Repressive Complex 2 (PRC2) to a Subset of Its Target Genes through Interaction with Human Polycomb-like (hPCL) Proteins

Gaylor Boulay, Marion Dubuissez, Capucine Van Rechem, Antoine Forget, Kristian Helin, Olivier Ayrault, Dominique Leprince

J Biol Chem. 2012 Mar 23; 287(13): 10509–10524. Published online 2012 Feb 7. doi: 10.1074/jbc.M111.320234

PMCID:: PMC3323039

Article PDF–3.9M

Select item 270505811.

REL, a member of the NF-?B family of transcription factors, is a newly defined risk locus for rheumatoid arthritis

Peter K. Gregersen, Chistopher I Amos, Annette T. Lee, Emily Lu, Elaine F. Remmers, Daniel L. Kastner, Michael F. Seldin, Lindsey A Criswell, Robert M. Plenge, V. Michael Holers, Ted Mikuls, Tuulikki Sokka, Larry W. Moreland, S. Louis Bridges, Gang Xie, Ann B. Begovich, Katherine A. Siminovitch

Nat Genet. Author manuscript; available in PMC 2010 Jan 1.

Published in final edited form as: Nat Genet. 2009 Jul; 41(7): 820–823. Published online 2009 Jun 7. doi: 10.1038/ng.395

PMCID:: PMC2705058

Article PDF–649K

Select item 304468512.

Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci

Alexandra Zhernakova, Eli A. Stahl, Gosia Trynka, Soumya Raychaudhuri, Eleanora A. Festen, Lude Franke, Harm-Jan Westra, Rudolf S. N. Fehrmann, Fina A. S. Kurreeman, Brian Thomson, Namrata Gupta, Jihane Romanos, Ross McManus, Anthony W. Ryan, Graham Turner, Elisabeth Brouwer, Marcel D. Posthumus, Elaine F. Remmers, Francesca Tucci, Rene Toes, Elvira Grandone, Maria Cristina Mazzilli, Anna Rybak, Bozena Cukrowska, Marieke J. H. Coenen, Timothy R. D. J. Radstake, Piet L. C. M. van Riel, Yonghong Li, Paul I. W. de Bakker, Peter K. Gregersen, Jane Worthington, Katherine A. Siminovitch, Lars Klareskog, Tom W. J. Huizinga, Cisca Wijmenga, Robert M. Plenge

PLoS Genet. 2011 Feb; 7(2): e1002004. Published online 2011 Feb 24. doi: 10.1371/journal.pgen.1002004

PMCID:: PMC3044685

Article PDF–421K

Select item 357058913.

An H3K36 methylation engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

Ling Cai, Scott B. Rothbart, Rui Lu, Bowen Xu, Wei-Yi Chen, Ashutosh Tripathy, Shira Rockowitz, Deyou Zheng, Dinshaw J Patel, C. David Allis, Brian D. Strahl, Jikui Song, Gang Greg Wang

Mol Cell. Author manuscript; available in PMC 2014 Feb 7.

Published in final edited form as: Mol Cell. 2013 Feb 7; 49(3): 571–582. Published online 2012 Dec 27. doi: 10.1016/j.molcel.2012.11.026

PMCID:: PMC3570589

Article PDF–4.3M

Select item 392693814.

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

Cecilia Ballaré, Martin Lange, Audrone Lapinaite, Gloria Mas Martin, Lluis Morey, Gloria Pascual, Robert Liefke, Bernd Simon, Yang Shi, Or Gozani, Teresa Carlomagno, Salvador Aznar Benitah, Luciano Di Croce

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Feb 17.

Published in final edited form as: Nat Struct Mol Biol. 2012 Dec; 19(12): 1257–1265. Published online 2012 Oct 28. doi: 10.1038/nsmb.2434

PMCID:: PMC3926938

Article PDF–4.0M

Select item 394409815.

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Yukinori Okada, Di Wu, Gosia Trynka, Towfique Raj, Chikashi Terao, Katsunori Ikari, Yuta Kochi, Koichiro Ohmura, Akari Suzuki, Shinji Yoshida, Robert R. Graham, Arun Manoharan, Ward Ortmann, Tushar Bhangale, Joshua C. Denny, Robert J. Carroll, Anne E. Eyler, Jeffrey D. Greenberg, Joel M. Kremer, Dimitrios A. Pappas, Lei Jiang, Jian Yin, Lingying Ye, Ding-Feng Su, Jian Yang, Gang Xie, Ed Keystone, Harm-Jan Westra, Tõnu Esko, Andres Metspalu, Xuezhong Zhou, Namrata Gupta, Daniel Mirel, Eli A. Stahl, Dorothée Diogo, Jing Cui, Katherine Liao, Michael H. Guo, Keiko Myouzen, Takahisa Kawaguchi, Marieke J.H. Coenen, Piet L.C.M. van Riel, Mart A.F.J. van de Laar, Henk-Jan Guchelaar, Tom W.J. Huizinga, Philippe Dieudé, Xavier Mariette, S. Louis Bridges, Jr., Alexandra Zhernakova, Rene E.M. Toes, Paul P. Tak, Corinne Miceli-Richard, So-Young Bang, Hye-Soon Lee, Javier Martin, Miguel A. Gonzalez-Gay, Luis Rodriguez-Rodriguez, Solbritt Rantapää-Dahlqvist, Lisbeth Ärlestig, Hyon K. Choi, Yoichiro Kamatani, Pilar Galan, Mark Lathrop, the RACI consortium, the GARNET consortium, Steve Eyre, John Bowes, Anne Barton, Niek de Vries, Larry W. Moreland, Lindsey A. Criswell, Elizabeth W. Karlson, Atsuo Taniguchi, Ryo Yamada, Michiaki Kubo, Jun S. Liu, Sang-Cheol Bae, Jane Worthington, Leonid Padyukov, Lars Klareskog, Peter K. Gregersen, Soumya Raychaudhuri, Barbara E. Stranger, Philip L. De Jager, Lude Franke, Peter M. Visscher, Matthew A. Brown, Hisashi Yamanaka, Tsuneyo Mimori, Atsushi Takahashi, Huji Xu, Timothy W. Behrens, Katherine A. Siminovitch, Shigeki Momohara, Fumihiko Matsuda, Kazuhiko Yamamoto, Robert M. Plenge

Nature. Author manuscript; available in PMC 2014 Aug 20.

Published in final edited form as: Nature. 2014 Feb 20; 506(7488): 376–381. Published online 2013 Dec 25. doi: 10.1038/nature12873

PMCID:: PMC3944098

Article PDF–1.9M

Select item 509804216.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Giorgio Oliviero, Gerard L. Brien, Ariane Waston, Gundula Streubel, Emilia Jerman, Darrell Andrews, Benjamin Doyle, Nayla Munawar, Kieran Wynne, John Crean, Adrian P. Bracken, Gerard Cagney

Mol Cell Proteomics. 2016 Nov; 15(11): 3450–3460. Published online 2016 Sep 15. doi: 10.1074/mcp.M116.062240

PMCID:: PMC5098042

Article PDF–1.9M

Select item 904055617.

A protein interaction landscape of breast cancer

Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan

Science. Author manuscript; available in PMC 2022 Apr 26.

Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066

PMCID:: PMC9040556

Article PDF–2.2M

Select item 464794118.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Article

Select item 874895819.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Article PDF–3.0M

Select item 407349420.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Article PDF–2.1M

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