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Select item 82174671.

Map2k5-Deficient Mice Manifest Phenotypes and Pathological Changes of Dopamine Deficiency in the Central Nervous System

Yumeng Huang, Pei Wang, Rodrigo Morales, Qi Luo, Jianfang Ma

Front Aging Neurosci. 2021; 13: 651638. Published online 2021 Jun 8. doi: 10.3389/fnagi.2021.651638

PMCID:: PMC8217467

Article PDF–19M

Select item 63937652.

MEK5 promotes lung adenocarcinoma

Adrián Sánchez-Fdez, María Jesús Ortiz-Ruiz, María Florencia Re-Louhau, Isabel Ramos, Óscar Blanco-Múñez, Dolores Ludeña, Mar Abad, Manuel Sánchez-Martín, Atanasio Pandiella, Azucena Esparís-Ogando

Eur Respir J. 2019 Feb; 53(2): 1801327. Published online 2019 Feb 28. doi: 10.1183/13993003.01327-2018

PMCID:: PMC6393765

Article PDF–478K

Select item 26143663.

Association of MEK5 with ERK5, but not ERK5 kinase activation, inhibits small ubiquitin-related modification of ERK5 kinase (ERK5-SUMOylation), and prevents diabetes-mediated exacerbation of left ventricular dysfunction after myocardial infarction

Tetsuro Shishido, Chang-Hoon Woo, Bo Ding, Carolyn McClain, Carlos A. Molina, Chen Yan, Jay Yang, Jun-ichi Abe

Circ Res. Author manuscript; available in PMC 2009 Jun 6.

Published in final edited form as: Circ Res. 2008 Jun 6; 102(11): 1416–1425. Published online 2008 May 8. doi: 10.1161/CIRCRESAHA.107.168138

PMCID:: PMC2614366

Article PDF–4.8M

Select item 24864214.

Non-redundant function of the MEK5–ERK5 pathway in thymocyte apoptosis

Sue J Sohn, Gavin M Lewis, Astar Winoto

EMBO J. 2008 Jul 9; 27(13): 1896–1906. Published online 2008 Jun 12. doi: 10.1038/emboj.2008.114

PMCID:: PMC2486421

Article PDF–476K

Select item 14302425.

Regulation of Nuclear Translocation of Extracellular Signal-Regulated Kinase 5 by Active Nuclear Import and Export Mechanisms

Kunio Kondoh, Kazuya Terasawa, Hiroko Morimoto, Eisuke Nishida

Mol Cell Biol. 2006 Mar; 26(5): 1679–1690. doi: 10.1128/MCB.26.5.1679-1690.2006

PMCID:: PMC1430242

Article PDF–1.0M

Select item 12802696.

A Novel Mitogen-Activated Protein Kinase Docking Site in the N Terminus of MEK5α Organizes the Components of the Extracellular Signal-Regulated Kinase 5 Signaling Pathway

Jan Seyfried, Xin Wang, Giorgi Kharebava, Cathy Tournier

Mol Cell Biol. 2005 Nov; 25(22): 9820–9828. doi: 10.1128/MCB.25.22.9820-9828.2005

PMCID:: PMC1280269

Article PDF–468K

Select item 44381297.

Inducible Activation of ERK5 MAP Kinase Enhances Adult Neurogenesis in the Olfactory Bulb and Improves Olfactory Function

Wenbin Wang, Song Lu, Tan Li, Yung-Wei Pan, Junhui Zou, Glen M. Abel, Lihong Xu, Daniel R. Storm, Zhengui Xia

J Neurosci. 2015 May 20; 35(20): 7833–7849. doi: 10.1523/JNEUROSCI.3745-14.2015

PMCID:: PMC4438129

Article PDF–8.5M

Select item 41156738.

Activation of Extracellular Signal-Regulated Kinase 5 Reduces Cardiac Apoptosis and Dysfunction via Inhibition of a Phosphodiesterase 3A/Inducible cAMP Early Repressor Feedback Loop

Chen Yan, Bo Ding, Tetsuro Shishido, Chang-Hoon Woo, Seigo Itoh, Kye-Im Jeon, Weimin Liu, Haodong Xu, Carolyn McClain, Carlos A. Molina, Burns C. Blaxall, Jun-ichi Abe

Circ Res. Author manuscript; available in PMC 2014 Jul 30.

Published in final edited form as: Circ Res. 2007 Mar 2; 100(4): 510–519. Published online 2007 Feb 1. doi: 10.1161/01.RES.0000259045.49371.9c

PMCID:: PMC4115673

Article PDF–1.3M

Select item 27292619.

MEK5 and ERK5 are mediators of the pro-myogenic actions of IGF-2

Emma J. Carter, Ruth A. Cosgrove, Ivelisse Gonzalez, Joan H. Eisemann, Fiona A. Lovett, Laura J. Cobb, Jennifer M. Pell

J Cell Sci. 2009 Sep 1; 122(17): 3104–3112. Published online 2009 Aug 4. doi: 10.1242/jcs.045757

PMCID:: PMC2729261

Article

Select item 12547510.

Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy

Rebekka L. Nicol, Norbert Frey, Gray Pearson, Melanie Cobb, James Richardson, Eric N. Olson

EMBO J. 2001 Jun 1; 20(11): 2757–2767. doi: 10.1093/emboj/20.11.2757

PMCID:: PMC125475

Article PDF–424K

Select item 275720111.

MEK5/ERK5 Signaling Modulates Endothelial Cell Migration and Focal Contact Turnover

Désirée Spiering, Mirco Schmolke, Nils Ohnesorge, Marc Schmidt, Matthias Goebeler, Joachim Wegener, Viktor Wixler, Stephan Ludwig

J Biol Chem. 2009 Sep 11; 284(37): 24972–24980. Published online 2009 Jul 15. doi: 10.1074/jbc.M109.042911

PMCID:: PMC2757201

Article PDF–2.1M

Select item 190006312.

Noncanonical Function of MEKK2 and MEK5 PB1 Domains for Coordinated Extracellular Signal-Regulated Kinase 5 and c-Jun N-Terminal Kinase Signaling

Kazuhiro Nakamura, Gary L. Johnson

Mol Cell Biol. 2007 Jun; 27(12): 4566–4577. Published online 2007 Apr 23. doi: 10.1128/MCB.00125-07

PMCID:: PMC1900063

Article PDF–630K

Select item 445113513.

BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival

Emilie Jacque, Edina Schweighoffer, Victor L.J. Tybulewicz, Steven C. Ley

J Exp Med. 2015 Jun 1; 212(6): 883–892. doi: 10.1084/jem.20142127

PMCID:: PMC4451135

Article PDF–2.1M

Select item 1042415014.

TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development

Erdyni N. Tsitsikov, Khanh P. Phan, Yufeng Liu, Alla V. Tsytsykova, Mike Kinter, Lauren Selland, Lori Garman, Courtney Griffin, Ian F. Dunn

iScience. 2023 Aug 18; 26(8): 107474. Published online 2023 Jul 25. doi: 10.1016/j.isci.2023.107474

PMCID:: PMC10424150

Article PDF–5.6M

Select item 32439615.

Knockout of ERK5 causes multiple defects in placental and embryonic development

Lijun Yan, Julia Carr, Peter R Ashby, Victoria Murry-Tait, Calum Thompson, J Simon C Arthur

BMC Dev Biol. 2003; 3: 11. Published online 2003 Dec 16. doi: 10.1186/1471-213X-3-11

PMCID:: PMC324396

Article PDF–1.2M

Select item 53877416.

Targeted Deletion of mek5 Causes Early Embryonic Death and Defects in the Extracellular Signal-Regulated Kinase 5/Myocyte Enhancer Factor 2 Cell Survival Pathway

Xin Wang, Anita J. Merritt, Jan Seyfried, Chun Guo, Emmanouil S. Papadakis, Katherine G. Finegan, Midori Kayahara, Jill Dixon, Raymond P. Boot-Handford, Elizabeth J. Cartwright, Ulrike Mayer, Cathy Tournier

Mol Cell Biol. 2005 Jan; 25(1): 336–345. doi: 10.1128/MCB.25.1.336-345.2005

PMCID:: PMC538774

Article PDF–773K

Select item 397505917.

Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon

Derek Spieler, Maria Kaffe, Franziska Knauf, José Bessa, Juan J. Tena, Florian Giesert, Barbara Schormair, Erik Tilch, Heekyoung Lee, Marion Horsch, Darina Czamara, Nazanin Karbalai, Christine von Toerne, Melanie Waldenberger, Christian Gieger, Peter Lichtner, Melina Claussnitzer, Ronald Naumann, Bertram Müller-Myhsok, Miguel Torres, Lillian Garrett, Jan Rozman, Martin Klingenspor, Valérie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Johannes Beckers, Sabine M. Hölter, Thomas Meitinger, Stefanie M. Hauck, Helmut Laumen, Wolfgang Wurst, Fernando Casares, Jose Luis Gómez-Skarmeta, Juliane Winkelmann

Genome Res. 2014 Apr; 24(4): 592–603. doi: 10.1101/gr.166751.113

PMCID:: PMC3975059

Article PDF–1.5M

Select item 333384218.

Targeted Deletion of ERK5 MAP Kinase in the Developing Nervous System Impairs Development of GABAergic Interneurons in the Main Olfactory Bulb and Behavioral Discrimination between Structurally Similar Odorants

Junhui Zou, Yung-Wei Pan, Zhenshan Wang, Shih-Yu Chang, Wenbin Wang, Xin Wang, Cathy Tournier, Daniel R. Storm, Zhengui Xia

J Neurosci. 2012 Mar 21; 32(12): 4118–4132. doi: 10.1523/JNEUROSCI.6260-11.2012

PMCID:: PMC3333842

Article PDF–4.5M

Select item 206386519.

M line–deficient titin causes cardiac lethality through impaired maturation of the sarcomere

Stefanie Weinert, Nora Bergmann, Xiuju Luo, Bettina Erdmann, Michael Gotthardt

J Cell Biol. 2006 May 22; 173(4): 559–570. doi: 10.1083/jcb.200601014

PMCID:: PMC2063865

Article PDF–2.2M

Select item 741599120.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Article PDF–2.0M

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