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Select item 80955461.

Differential Expression of Utrophin‐A and ‐B Promoters in the Central Nervous System (CNS) of Normal and Dystrophic mdx Mice

Santhosh M. Baby, Sasha Bogdanovich, Gabriel Willmann, Utpal Basu, Olga Lozynska, Tejvir S. Khurana

Brain Pathol. 2010 Mar; 20(2): 323–342. Published online 2009 May 27. doi: 10.1111/j.1750-3639.2009.00275.x

PMCID:: PMC8095546

Article PDF–2.2M

Select item 46301132.

Sparing of the Extraocular Muscles in mdx Mice with Absent or Reduced Utrophin Expression: A Life Span Analysis

Abby A. McDonald, Sadie L. Hebert, Linda K. McLoon

Neuromuscul Disord. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: Neuromuscul Disord. 2015 Nov; 25(11): 873–887. Published online 2015 Sep 6. doi: 10.1016/j.nmd.2015.09.001

PMCID:: PMC4630113

Article PDF–619K

Select item 45218233.

Cis-Acting Sequence Elements and Upstream Open Reading Frame in Mouse Utrophin-A 5'-UTR Repress Cap-Dependent Translation

Trinath Ghosh, Utpal Basu

PLoS One. 2015; 10(7): e0134809. Published online 2015 Jul 31. doi: 10.1371/journal.pone.0134809

PMCID:: PMC4521823

Article PDF–823K

Select item 32465024.

Translational Regulation of Utrophin by miRNAs

Utpal Basu, Olga Lozynska, Catherine Moorwood, Gopal Patel, Steve D. Wilton, Tejvir S. Khurana

PLoS One. 2011; 6(12): e29376. Published online 2011 Dec 27. doi: 10.1371/journal.pone.0029376

PMCID:: PMC3246502

Article PDF–634K

Select item 27508755.

The synaptic CT carbohydrate modulates binding and expression of extracellular matrix proteins in skeletal muscle: partial dependence on utrophin

Jung Hae Yoon, Kumaran Chandrasekharan, Rui Xu, Matthew Glass, Neha Singhal, Paul T. Martin

Mol Cell Neurosci. Author manuscript; available in PMC 2010 Aug 1.

Published in final edited form as: Mol Cell Neurosci. 2009 Aug; 41(4): 448–463. Published online 2009 May 12. doi: 10.1016/j.mcn.2009.04.013

PMCID:: PMC2750875

Article PDF–2.1M

Select item 26994866.

Heregulin-induced Epigenetic Regulation of the Utrophin-A Promoter

Utpal Basu, Mads Gyrd-Hansen, Santhosh M. Baby, Olga Lozynska, Thomas O. B. Krag, Claus J. Jensen, Morten Frödin, Tejvir S. Khurana

FEBS Lett. Author manuscript; available in PMC 2009 Jun 22.

Published in final edited form as: FEBS Lett. 2007 Sep 4; 581(22): 4153–4158. Published online 2007 Jul 23. doi: 10.1016/j.febslet.2007.07.021

PMCID:: PMC2699486

Article PDF–920K

Select item 26431337.

Microutrophin Delivery Through rAAV6 Increases Lifespan and Improves Muscle Function in Dystrophic Dystrophin/Utrophin-deficient Mice

Guy L Odom, Paul Gregorevic, James M Allen, Eric Finn, Jeffrey S Chamberlain

Mol Ther. Author manuscript; available in PMC 2009 Feb 16.

Published in final edited form as: Mol Ther. 2008 Sep; 16(9): 1539–1545. Published online 2008 Jul 29. doi: 10.1038/mt.2008.149

PMCID:: PMC2643133

Article PDF–3.2M

Select item 21508208.

Distinct regions in the 3′ untranslated region are responsible for targeting and stabilizing utrophin transcripts in skeletal muscle cells

Anthony O. Gramolini, Guy Bélanger, Bernard J. Jasmin

J Cell Biol. 2001 Sep 17; 154(6): 1173–1184. doi: 10.1083/jcb.200101108

PMCID:: PMC2150820

Article PDF–368K

Select item 21324999.

Postsynaptic Abnormalities at the Neuromuscular Junctions of Utrophin-deficient Mice

Anne E. Deconinck, Allyson C. Potter, Jonathon M. Tinsley, Sarah J. Wood, Ruth Vater, Carol Young, Laurent Metzinger, Angela Vincent, Clarke R. Slater, Kay E. Davies

J Cell Biol. 1997 Feb 24; 136(4): 883–894. doi: 10.1083/jcb.136.4.883

PMCID:: PMC2132499

Article PDF–707K

Select item 213249610.

Subtle Neuromuscular Defects in Utrophin-deficient Mice

R. Mark Grady, John P. Merlie, Joshua R. Sanes

J Cell Biol. 1997 Feb 24; 136(4): 871–882. doi: 10.1083/jcb.136.4.871

PMCID:: PMC2132496

Article PDF–1.0M

Select item 197484311.

Pathological pattern of Mdx mice diaphragm correlates with gradual expression of the short utrophin isoform Up71

Karim Hnia, Sylvie Tuffery-Giraud, Marianne Vermaelen, Gerald Hugon, Delphine Chazalette, Ahmed Masmoudi, François Rivier, Dominique Mornet

Biochim Biophys Acta. Author manuscript; available in PMC 2007 Sep 25.

Published in final edited form as: Biochim Biophys Acta. 2006 Mar; 1762(3): 362–372. doi: 10.1016/j.bbadis.2005.11.006

PMCID:: PMC1974843

Article

Select item 14584712.

Molecular and functional analysis of the utrophin promoter.

C L Dennis, J M Tinsley, A E Deconinck, K E Davies

Nucleic Acids Res. 1996 May 1; 24(9): 1646–1652. doi: 10.1093/nar/24.9.1646

PMCID:: PMC145847

Summary PDF–120K

Select item 9668913.

The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy

Kelly J. Perkins, Edward A. Burton, Kay E. Davies

Nucleic Acids Res. 2001 Dec 1; 29(23): 4843–4850. doi: 10.1093/nar/29.23.4843

PMCID:: PMC96689

Article PDF–509K

Select item 2418414.

A second promoter provides an alternative target for therapeutic up-regulation of utrophin in Duchenne muscular dystrophy

Edward A. Burton, Jonathon M. Tinsley, Paul J. Holzfeind, Nanda R. Rodrigues, Kay E. Davies

Proc Natl Acad Sci U S A. 1999 Nov 23; 96(24): 14025–14030. doi: 10.1073/pnas.96.24.14025

PMCID:: PMC24184

Article PDF–320K

Select item 1014431715.

A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [¹⁸F]FEPPA PET

Joanne M. Tang, Andrew McClennan, Linshan Liu, Jennifer Hadway, John A. Ronald, Justin W. Hicks, Lisa Hoffman, Udunna C. Anazodo

Int J Mol Sci. 2023 Apr; 24(8): 7522. Published online 2023 Apr 19. doi: 10.3390/ijms24087522

PMCID:: PMC10144317

Article PDF–3.8M

Select item 1003985116.

Endogenous bioluminescent reporters reveal a sustained increase in utrophin gene expression upon EZH2 and ERK1/2 inhibition

Hannah J. Gleneadie, Beatriz Fernandez-Ruiz, Alessandro Sardini, Mathew Van de Pette, Andrew Dimond, Rab K. Prinjha, James McGinty, Paul M. W. French, Hakan Bagci, Matthias Merkenschlager, Amanda G. Fisher

Commun Biol. 2023; 6: 318. Published online 2023 Mar 25. doi: 10.1038/s42003-023-04666-9

PMCID:: PMC10039851

Article PDF–3.3M

Select item 908881117.

Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression

Min Ho Song, Jimeen Yoo, Jae Gyun Oh, Hyun Kook, Woo Jin Park, Dongtak Jeong

Front Cardiovasc Med. 2022; 9: 763544. Published online 2022 Apr 26. doi: 10.3389/fcvm.2022.763544

PMCID:: PMC9088811

Article PDF–4.4M

Select item 821725218.

Plasma lipidomic analysis shows a disease progression signature in mdx mice

Roula Tsonaka, Alexandre Seyer, Annemieke Aartsma-Rus, Pietro Spitali

Sci Rep. 2021; 11: 12993. Published online 2021 Jun 21. doi: 10.1038/s41598-021-92406-6

PMCID:: PMC8217252

Article PDF–3.4M

Select item 814710519.

Early Inflammation in Muscular Dystrophy Differs between Limb and Respiratory Muscles and Increases with Dystrophic Severity

Zachary M. Howard, Jeovanna Lowe, Anton J. Blatnik, 3^rd, Deztani Roberts, Arthur H.M. Burghes, Shyam S. Bansal, Jill A. Rafael-Fortney

Am J Pathol. 2021 Apr; 191(4): 730–747. doi: 10.1016/j.ajpath.2021.01.008

PMCID:: PMC8147105

Article PDF–4.4M

Select item 811918120.

Micro-dystrophin gene therapy prevents heart failure in an improved Duchenne muscular dystrophy cardiomyopathy mouse model

Zachary M. Howard, Lisa E. Dorn, Jeovanna Lowe, Megan D. Gertzen, Pierce Ciccone, Neha Rastogi, Guy L. Odom, Federica Accornero, Jeffrey S. Chamberlain, Jill A. Rafael-Fortney

JCI Insight. 2021 Apr 8; 6(7): e146511. Published online 2021 Apr 8. doi: 10.1172/jci.insight.146511