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Select item 101490041.

Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis

Timon Fiedler, Richard Fairless, Kira Pichi, Roman Fischer, Fabian Richter, Roland E. Kontermann, Klaus Pfizenmaier, Ricarda Diem, Sarah K. Williams

J Neuroinflammation. 2023; 20: 100. Published online 2023 Apr 30. doi: 10.1186/s12974-023-02784-z

PMCID:: PMC10149004

Article PDF–3.2M

Select item 93144602.

TNFR2 depletion reduces psoriatic inflammation in mice via downregulating specific dendritic cell populations in lymph nodes and inhibiting IL-23/IL-17 pathways

Unnikrishnan M. Chandrasekharan, Raminderjit Kaur, Jennifer E. Harvey, Chad Braley, Vandana Rai, MacKenzie Lee, Nicholas de Windt, Jason Hsieh, Ritika Jaini, Defne Bayik, Rachel G. Scheraga, Anthony P. Fernandez, Paul E. DiCorleto, M. Elaine Husni

J Invest Dermatol. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: J Invest Dermatol. 2022 Aug; 142(8): 2159–2172.e9. Published online 2022 Jan 26. doi: 10.1016/j.jid.2021.12.036

PMCID:: PMC9314460

Article PDF–4.7M

Select item 88108723.

Pathway-specific TNF-mediated metaplasticity in hippocampal area CA1

Anurag Singh, Shruthi Sateesh, Owen D. Jones, Wickliffe C. Abraham

Sci Rep. 2022; 12: 1746. Published online 2022 Feb 2. doi: 10.1038/s41598-022-05844-1

PMCID:: PMC8810872

Article PDF–3.6M

Select item 78882114.

Tumor Necrosis Factor α Receptor Type 1 Activation in the Hypothalamic Paraventricular Nucleus Contributes to Glutamate Signaling and Angiotensin II-Dependent Hypertension

Clara Woods, Jose Marques-Lopes, Natalina H. Contoreggi, Teresa A. Milner, Virginia M. Pickel, Gang Wang, Michael J. Glass

J Neurosci. 2021 Feb 10; 41(6): 1349–1362. doi: 10.1523/JNEUROSCI.2360-19.2020

PMCID:: PMC7888211

Article PDF–2.5M

Select item 76966245.

Tumor Necrosis Factor Receptor-1 (p55) Deficiency Attenuates Tumor Growth and Intratumoral Angiogenesis and Stimulates CD8⁺ T Cell Function in Melanoma

Yamila I. Rodriguez, Ludmila E. Campos, Melina G. Castro, Nadia Bannoud, Ada G. Blidner, Verónica P. Filippa, Diego O. Croci, Gabriel A. Rabinovich, Sergio E. Alvarez

Cells. 2020 Nov; 9(11): 2469. Published online 2020 Nov 13. doi: 10.3390/cells9112469

PMCID:: PMC7696624

Article PDF–4.2M

Select item 75561366.

TNFR2 is required for RIP1-dependent cell death in human leukemia

Júlia Aguadé-Gorgorió, Scott McComb, Cornelia Eckert, Anna Guinot, Blerim Marovca, Caterina Mezzatesta, Silvia Jenni, Liridon Abduli, Martin Schrappe, Maria Pamela Dobay, Martin Stanulla, Arend von Stackelberg, Gunnar Cario, Jean-Pierre Bourquin, Beat C. Bornhauser

Blood Adv. 2020 Oct 13; 4(19): 4823–4833. Published online 2020 Oct 7. doi: 10.1182/bloodadvances.2019000796

PMCID:: PMC7556136

Article PDF–1.3M

Select item 75272227.

Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4⁺Foxp3⁺ regulatory T cells

Tianzhen He, De Yang, Xiao-Qing Li, Mengmeng Jiang, Md Sahidul Islam, Shaokui Chen, Yibo Chen, Yang Yang, Chon-Kit Chou, Anna L. Trivett, Joost J. Oppenheim, Xin Chen

Sci Adv. 2020 Oct; 6(40): eaba6584. Published online 2020 Sep 30. doi: 10.1126/sciadv.aba6584

PMCID:: PMC7527222

Article PDF–4.9M

Select item 74761788.

Tumor necrosis factor alpha receptor 1 deficiency in hepatocytes does not protect from non-alcoholic steatohepatitis, but attenuates insulin resistance in mice

Sena Bluemel, Yanhan Wang, Suhan Lee, Bernd Schnabl

World J Gastroenterol. 2020 Sep 7; 26(33): 4933–4944. Published online 2020 Sep 7. doi: 10.3748/wjg.v26.i33.4933

PMCID:: PMC7476178

Article PDF–6.1M

Select item 73631149.

Structural optimization of a TNFR1-selective antagonistic TNFα mutant to create new-modality TNF-regulating biologics

Masaki Inoue, Yuta Tsuji, Chinatsu Yoshimine, Shota Enomoto, Yuki Morita, Natsuki Osaki, Masahiro Kunishige, Midori Miki, Shota Amano, Kanako Yamashita, Haruhiko Kamada, Yasuo Tsutsumi, Shin-ichi Tsunoda

J Biol Chem. 2020 Jul 10; 295(28): 9379–9391. Published online 2020 May 12. doi: 10.1074/jbc.RA120.012723

PMCID:: PMC7363114

Article PDF–3.5M

Select item 709401510.

Proteomic profiling of HTLV-1 carriers and ATL patients reveals sTNFR2 as a novel diagnostic biomarker for acute ATL

Carmina Louise Hugo Guerrero, Yoshiko Yamashita, Megumi Miyara, Naoki Imaizumi, Megumi Kato, Shugo Sakihama, Masaki Hayashi, Takashi Miyagi, Kaori Karimata, Junnosuke Uchihara, Kazuiku Ohshiro, Junpei Todoroki, Sawako Nakachi, Satoko Morishima, Kennosuke Karube, Yuetsu Tanaka, Hiroaki Masuzaki, Takuya Fukushima

Blood Adv. 2020 Mar 24; 4(6): 1062–1071. Published online 2020 Mar 20. doi: 10.1182/bloodadvances.2019001429

Correction in:: Blood Adv. 2020 Apr 28; 4(8): 1647.

PMCID:: PMC7094015

Article PDF–1.2M

Select item 673045811.

Tumor Necrosis Factor Death Receptor Signaling Cascade Is Required for Amyloid-β Protein-Induced Neuron Death

Rena Li, Libang Yang, Kristina Lindholm, Yoshihiro Konishi, Xu Yue, Harald Hampel, Dai Zhang, Yong Shen

J Neurosci. 2004 Feb 18; 24(7): 1760–1771. doi: 10.1523/JNEUROSCI.4580-03.2004

PMCID:: PMC6730458

Article PDF–701K

Select item 657321812.

Mice Lacking the TNF 55 kDa Receptor Fail to Sleep More After TNFα Treatment

Jidong Fang, Ying Wang, James M. Krueger

J Neurosci. 1997 Aug 1; 17(15): 5949–5955. doi: 10.1523/JNEUROSCI.17-15-05949.1997

PMCID:: PMC6573218

Article PDF–301K

Select item 631827713.

Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice

Vanessa Lamontain, Tobias Schmid, Dorothea Weber-Steffens, David Zeller, Zsuzsa Jenei-Lanzl, Harald Wajant, Rainer H Straub, Daniela N Männel

Cell Mol Immunol. 2019 Jan; 16(1): 65–74. Published online 2018 Jan 29. doi: 10.1038/cmi.2017.138

PMCID:: PMC6318277

Article PDF–4.1M

Select item 613414314.

TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling

Daniela Siegmund, Martin Ehrenschwender, Harald Wajant

Cell Death Dis. 2018 Sep; 9(9): 921. Published online 2018 Sep 11. doi: 10.1038/s41419-018-0973-3

PMCID:: PMC6134143

Article PDF–1.6M

Select item 613396415.

Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis

Sarah K. Williams, Richard Fairless, Olaf Maier, Patricia C. Liermann, Kira Pichi, Roman Fischer, Ulrich L. M. Eisel, Roland Kontermann, Andreas Herrmann, Babette Weksler, Nacho Romero, Pierre-Olivier Couraud, Klaus Pfizenmaier, Ricarda Diem

Sci Rep. 2018; 8: 13628. Published online 2018 Sep 11. doi: 10.1038/s41598-018-31957-7

PMCID:: PMC6133964

Article PDF–8.3M

Select item 608544816.

TNFR1 Signaling Contributes to T Cell Anergy During Staphylococcus aureus Sepsis

Camila Ledo, Cintia D. Gonzalez, Carolina V. Poncini, Marta Mollerach, Marisa I. Gómez

Front Cell Infect Microbiol. 2018; 8: 259. Published online 2018 Aug 3. doi: 10.3389/fcimb.2018.00259

PMCID:: PMC6085448

Article PDF–1.4M

Select item 589313917.

Curcumin Requires Tumor Necrosis Factor a Signaling to Alleviate Cognitive Impairment Elicited by Lipopolysaccharide

E.M. Kawamoto, C. Scavone, M.P. Mattson, S. Camandola

Neurosignals. Author manuscript; available in PMC 2018 Apr 10.

Published in final edited form as: Neurosignals. 2013; 21(1-2): 75–88. Published online 2012 May 9. doi: 10.1159/000336074

PMCID:: PMC5893139

Article PDF–940K

Select item 588790918.

Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease

Sophie Steeland, Nina Gorlé, Charysse Vandendriessche, Sriram Balusu, Marjana Brkic, Caroline Van Cauwenberghe, Griet Van Imschoot, Elien Van Wonterghem, Riet De Rycke, Anneke Kremer, Saskia Lippens, Edward Stopa, Conrad E Johanson, Claude Libert, Roosmarijn E Vandenbroucke

EMBO Mol Med. 2018 Apr; 10(4): e8300. Published online 2018 Feb 22. doi: 10.15252/emmm.201708300

PMCID:: PMC5887909

Article PDF–4.6M

Select item 588170519.

Inducible Colonic M Cells Are Dependent on TNFR2 but Not Ltβr, Identifying Distinct Signalling Requirements for Constitutive Versus Inducible M Cells

Erinn A. Parnell, Erin M. Walch, David D. Lo

J Crohns Colitis. 2017 Jun; 11(6): 751–760. Published online 2016 Dec 15. doi: 10.1093/ecco-jcc/jjw212

PMCID:: PMC5881705

Article PDF–5.4M

Select item 579911420.

TNF-α/TNFR1 Signaling is Required for the Full Expression of Acute and Chronic Itch in Mice via Peripheral and Central Mechanisms

Xiuhua Miao, Ya Huang, Teng-Teng Liu, Ran Guo, Bing Wang, Xue-Long Wang, Li-Hua Chen, Yan Zhou, Ru-Rong Ji, Tong Liu

Neurosci Bull. 2018 Feb; 34(1): 42–53. Published online 2017 Apr 1. doi: 10.1007/s12264-017-0124-3

PMCID:: PMC5799114

Article PDF–2.6M

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