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Select item 107242681.

Myeloid deletion of talin-1 reduces mucosal macrophages and protects mice from colonic inflammation

Yvonne L. Latour, Kara M. McNamara, Margaret M. Allaman, Daniel P. Barry, Thaddeus M. Smith, Mohammad Asim, Kamery J. Williams, Caroline V. Hawkins, Justin Jacobse, Jeremy A. Goettel, Alberto G. Delgado, M. Blanca Piazuelo, M. Kay Washington, Alain P. Gobert, Keith T. Wilson

Sci Rep. 2023; 13: 22368. Published online 2023 Dec 15. doi: 10.1038/s41598-023-49614-z

PMCID:: PMC10724268

Article PDF–6.1M

Select item 100380392.

Epithelial talin-1 protects mice from citrobacter rodentium-induced colitis by restricting bacterial crypt intrusion and enhancing t cell immunity

Yvonne L. Latour, Margaret M. Allaman, Daniel P. Barry, Thaddeus M. Smith, Kamery J. Williams, Kara M. McNamara, Justin Jacobse, Jeremy A. Goettel, Alberto G. Delgado, M. Blanca Piazuelo, Shilin Zhao, Alain P. Gobert, Keith T. Wilson

Gut Microbes. 2023; 15(1): 2192623. Published online 2023 Mar 23. doi: 10.1080/19490976.2023.2192623

PMCID:: PMC10038039

Article PDF–11M

Select item 85189773.

Peptide‐PAINT Enables Investigation of Endogenous Talin with Molecular Scale Resolution in Cells and Tissues

Lisa S. Fischer, Dr. Thomas Schlichthaerle, Dr. Anna Chrostek‐Grashoff, Prof. Dr. Carsten Grashoff

Chembiochem. 2021 Oct 1; 22(19): 2872–2879. Published online 2021 Jul 30. doi: 10.1002/cbic.202100301

PMCID:: PMC8518977

Article PDF–1.6M

Select item 84419684.

Talin-Dependent Integrin Activation is Required for Endothelial Proliferation and Postnatal Angiogenesis

Fadi E. Pulous, Jamie C. Carnevale, Zaki Al-Yafeai, Brenna H. Pearson, Jamie A.G. Hamilton, Curtis J. Henry, A. Wayne Orr, Brian G. Petrich

Angiogenesis. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Angiogenesis. 2021 Feb; 24(1): 177–190. Published online 2020 Oct 28. doi: 10.1007/s10456-020-09756-4

PMCID:: PMC8441968

Article PDF–1.0M

Select item 77686825.

Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding

Pingfeng Zhang, Latifeh Azizi, Sampo Kukkurainen, Tong Gao, Mo Baikoghli, Marie-Claude Jacquier, Yijuan Sun, Juha A. E. Määttä, R. Holland Cheng, Bernhard Wehrle-Haller, Vesa P. Hytönen, Jinhua Wu

Proc Natl Acad Sci U S A. 2020 Dec 22; 117(51): 32402–32412. Published online 2020 Dec 7. doi: 10.1073/pnas.2014583117

PMCID:: PMC7768682

Article PDF–2.4M

Select item 74746356.

Talin folding as the tuning fork of cellular mechanotransduction

Rafael Tapia-Rojo, Álvaro Alonso-Caballero, Julio M. Fernández

Proc Natl Acad Sci U S A. 2020 Sep 1; 117(35): 21346–21353. Published online 2020 Aug 17. doi: 10.1073/pnas.2004091117

PMCID:: PMC7474635

Article PDF–4.4M

Select item 74727137.

Talin-1 is the principal platelet Rap1 effector of integrin activation

Frederic Lagarrigue, David S. Paul, Alexandre R. Gingras, Andrew J. Valadez, Hao Sun, Jenny Lin, Monica N. Cuevas, Jailal N. Ablack, Miguel Alejandro Lopez-Ramirez, Wolfgang Bergmeier, Mark H. Ginsberg

Blood. 2020 Sep 3; 136(10): 1180–1190. Prepublished online 2020 Jun 9. doi: 10.1182/blood.2020005348

PMCID:: PMC7472713

Article

Select item 73981628.

Talin1 controls dendritic cell activation by regulating TLR complex assembly and signaling

Thomas Jun Feng Lim, Maegan Bunjamin, Christiane Ruedl, I-hsin Su

J Exp Med. 2020 Aug 3; 217(8): e20191810. Published online 2020 May 21. doi: 10.1084/jem.20191810

PMCID:: PMC7398162

Article PDF–5.7M

Select item 63440429.

PIPKIγ and talin couple phosphoinositide and adhesion signaling to control the epithelial to mesenchymal transition

N Thapa, X Tan, S Choi, T Wise, RA Anderson

Oncogene. Author manuscript; available in PMC 2019 Jan 23.

Published in final edited form as: Oncogene. 2017 Feb 16; 36(7): 899–911. Published online 2016 Jul 25. doi: 10.1038/onc.2016.267

PMCID:: PMC6344042

Article PDF–2.9M

Select item 552704810.

Thrombopoiesis is spatially regulated by the bone marrow vasculature

David Stegner, Judith M. M. vanEeuwijk, Oğuzhan Angay, Maximilian G. Gorelashvili, Daniela Semeniak, Jürgen Pinnecker, Patrick Schmithausen, Imke Meyer, Mike Friedrich, Sebastian Dütting, Christian Brede, Andreas Beilhack, Harald Schulze, Bernhard Nieswandt, Katrin G. Heinze

Nat Commun. 2017; 8: 127. Published online 2017 Jul 25. doi: 10.1038/s41467-017-00201-7

PMCID:: PMC5527048

Article PDF–4.9M

Select item 494105111.

The mechanical response of talin

Mingxi Yao, Benjamin T. Goult, Benjamin Klapholz, Xian Hu, Christopher P. Toseland, Yingjian Guo, Peiwen Cong, Michael P. Sheetz, Jie Yan

Nat Commun. 2016; 7: 11966. Published online 2016 Jul 7. doi: 10.1038/ncomms11966

PMCID:: PMC4941051

Article PDF–3.7M

Select item 393415912.

Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance

Xuefei Tian, Jin Ju Kim, Susan M. Monkley, Nanami Gotoh, Ramiro Nandez, Keita Soda, Kazunori Inoue, Daniel M. Balkin, Hossam Hassan, Sung Hyun Son, Yashang Lee, Gilbert Moeckel, David A. Calderwood, Lawrence B. Holzman, David R. Critchley, Roy Zent, Jochen Reiser, Shuta Ishibe

J Clin Invest. 2014 Mar 3; 124(3): 1098–1113. Published online 2014 Feb 17. doi: 10.1172/JCI69778

Correction in:: J Clin Invest. 2015 Feb 2; 125(2): 882.

PMCID:: PMC3934159

Article PDF–8.3M

Select item 305659613.

Talin-dependent integrin activation is required for fibrin clot retraction by platelets

Jacob R. Haling, Susan J. Monkley, David R. Critchley, Brian G. Petrich

Blood. 2011 Feb 3; 117(5): 1719–1722. Prepublished online 2010 Oct 22. doi: 10.1182/blood-2010-09-305433

PMCID:: PMC3056596

Article

Select item 298170514.

Calpain- and talin-dependent control of microvascular pericyte contractility and cellular stiffness

Maciej Kotecki, Adam S. Zeiger, Krystyn Van Vliet, Ira M. Herman

Microvasc Res. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: Microvasc Res. 2010 Dec; 80(3): 339–348. Published online 2010 Aug 12. doi: 10.1016/j.mvr.2010.07.012

PMCID:: PMC2981705

Article PDF–898K

Select item 268569115.

The Structure of an Interdomain Complex That Regulates Talin Activity

Benjamin T. Goult, Neil Bate, Nicholas J. Anthis, Kate L. Wegener, Alexandre R. Gingras, Bipin Patel, Igor L. Barsukov, Iain D. Campbell, Gordon C. K. Roberts, David R. Critchley

J Biol Chem. 2009 May 29; 284(22): 15097–15106. doi: 10.1074/jbc.M900078200

PMCID:: PMC2685691

Article PDF–821K

Select item 256232416.

Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle

Francesco J. Conti, Amanda Felder, Sue Monkley, Martin Schwander, Malcolm R. Wood, Richard Lieber, David Critchley, Ulrich Müller

Development. Author manuscript; available in PMC 2008 Oct 6.

Published in final edited form as: Development. 2008 Jun; 135(11): 2043–2053. Published online 2008 Apr 23. doi: 10.1242/dev.015818

PMCID:: PMC2562324

Article PDF–6.8M

Select item 253297317.

Structural model and functional significance of pH-dependent talin–actin binding for focal adhesion remodeling

J. Srivastava, G. Barreiro, S. Groscurth, A. R. Gingras, B. T. Goult, D. R. Critchley, M. J. S. Kelly, M. P. Jacobson, D. L. Barber

Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38): 14436–14441. Published online 2008 Sep 9. doi: 10.1073/pnas.0805163105

PMCID:: PMC2532973

Article PDF–1.0M

Select item 252236818.

Structural basis for the autoinhibition of talin in regulating integrin activation

Esen Goksoy, Yan-Qing Ma, Xiaoxia Wang, Xiangming Kong, Dhanuja Perera, Edward F. Plow, Jun Qin

Mol Cell. Author manuscript; available in PMC 2009 Jul 11.

Published in final edited form as: Mol Cell. 2008 Jul 11; 31(1): 124–133. doi: 10.1016/j.molcel.2008.06.011

PMCID:: PMC2522368

Article PDF–1.9M

Select item 216839619.

The structure of the C-terminal actin-binding domain of talin

Alexandre R Gingras, Neil Bate, Benjamin T Goult, Larnele Hazelwood, Ilona Canestrelli, J Günter Grossmann, HongJun Liu, Nicholas S M Putz, Gordon C K Roberts, Niels Volkmann, Dorit Hanein, Igor L Barsukov, David R Critchley

EMBO J. 2008 Jan 23; 27(2): 458–469. Published online 2007 Dec 20. doi: 10.1038/sj.emboj.7601965