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Items: 1 to 20 of 178

1.
GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers
Liat Ravid Lustig, Abhishek Sampath Kumar, Till Schwämmle, Ilona Dunkel, Gemma Noviello, Elodie Limberg, Raha Weigert, Guido Pacini, René Buschow, Afrah Ghauri, Maximilian Stötzel, Lars Wittler, Alexander Meissner, Edda G. Schulz
Nat Cell Biol. 2023; 25(11): 1704–1715. Published online 2023 Nov 6. doi: 10.1038/s41556-023-01266-x
PMCID:
PMC10635832
ArticlePDF–13M
2.
Xist exerts gene-specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis
Tianqi Yang, Jianhong Ou, Eda Yildirim
Nat Commun. 2022; 13: 4464. Published online 2022 Aug 1. doi: 10.1038/s41467-022-32273-5
PMCID:
PMC9343370
ArticlePDF–3.1M
3.
Elastic dosage compensation by X-chromosome upregulation
Antonio Lentini, Huaitao Cheng, J. C. Noble, Natali Papanicolaou, Christos Coucoravas, Nathanael Andrews, Qiaolin Deng, Martin Enge, Björn Reinius
Nat Commun. 2022; 13: 1854. Published online 2022 Apr 6. doi: 10.1038/s41467-022-29414-1
PMCID:
PMC8987076
ArticlePDF–3.4M
4.
Knockdown of XIST up‐regulates 263294miR‐340‐5p to relieve myocardial ischaemia–reperfusion injury via inhibiting cyclin D1
Qijun Bai, Yan Li, Kunpeng Song, Jie Huang, Li Qin
ESC Heart Fail. 2022 Apr; 9(2): 1050–1060. Published online 2021 Dec 30. doi: 10.1002/ehf2.13766
PMCID:
PMC8934972
ArticlePDF–31M
5.
Haploid mouse germ cell precursors from embryonic stem cells reveal Xist activation from a single X chromosome
Eishi Aizawa, Corinne Kaufmann, Sarah Sting, Sarah Boigner, Remo Freimann, Giulio Di Minin, Anton Wutz
Stem Cell Reports. 2022 Jan 11; 17(1): 43–52. Published online 2021 Dec 16. doi: 10.1016/j.stemcr.2021.11.006
PMCID:
PMC8758942
ArticlePDF–1.7M
6.
Xist nucleates local protein gradients to propagate silencing across the X chromosome
Yolanda Markaki, Johnny Gan Chong, Yuying Wang, Elsie C. Jacobson, Christy Luong, Shawn Y.X. Tan, Davide Maestrini, Abhik Banerjee, Bhaven A. Mistry, Iris Dror, Francois Dossin, Johannes Schöneberg, Edith Heard, Mitchell Guttman, Tom Chou, Kathrin Plath
Cell. Author manuscript; available in PMC 2022 Dec 9.
Published in final edited form as: Cell. 2021 Dec 9; 184(25): 6174–6192.e32. Published online 2021 Nov 4. doi: 10.1016/j.cell.2021.10.022
Correction in:
Cell. 2021 Dec 9; 184(25): 6212.
PMCID:
PMC8671326
ArticlePDF–2.7M
7.
Long non-coding RNA XIST promotes cerebral ischemia/reperfusion injury by modulating miR-27a-3p/FOXO3 signaling
Hua Zhang, Junyong Xia, Qiushan Hu, Liqin Xu, Hongyan Cao, Xu Wang, Min Cao
Mol Med Rep. 2021 Aug; 24(2): 566. Published online 2021 Jun 7. doi: 10.3892/mmr.2021.12205
PMCID:
PMC8201472
ArticlePDF–7.5M
8.
A protein assembly mediates Xist localization and gene silencing
Amy Pandya-Jones, Yolanda Markaki, Jacques Serizay, Tsotne Chitiashvili, Walter Mancia, Andrey Damianov, Costantinos Chronis, Bernadett Papp, Chun-Kan Chen, Robin McKee, Xiao-Jun Wang, Anthony Chau, Shan Sabri, Heinrich Leonhardt, Sika Zheng, Mitchell Guttman, Douglas. L. Black, Kathrin Plath
Nature. Author manuscript; available in PMC 2021 Mar 9.
Published in final edited form as: Nature. 2020 Nov; 587(7832): 145–151. Published online 2020 Sep 9. doi: 10.1038/s41586-020-2703-0
Correction in:
Nature. 2020 Oct 2
PMCID:
PMC7644664
ArticlePDF–5.7M
9.
The role of Xist‐mediated Polycomb recruitment in the initiation of X‐chromosome inactivation
Aurélie Bousard, Ana Cláudia Raposo, Jan Jakub Żylicz, Christel Picard, Vanessa Borges Pires, Yanyan Qi, Cláudia Gil, Laurène Syx, Howard Y Chang, Edith Heard, Simão Teixeira da Rocha
EMBO Rep. 2019 Oct 4; 20(10): e48019. Published online 2019 Aug 27. doi: 10.15252/embr.201948019
PMCID:
PMC6776897
ArticlePDF–1.8M
10.
Xist deletional analysis reveals a co-dependency between Xist RNA and Polycomb complexes for spreading along the inactive X
David Colognori, Hongjae Sunwoo, Andrea Kriz, Chen-Yu Wang, Jeannie T. Lee
Mol Cell. Author manuscript; available in PMC 2020 Apr 4.
Published in final edited form as: Mol Cell. 2019 Apr 4; 74(1): 101–117.e10. Published online 2019 Feb 28. doi: 10.1016/j.molcel.2019.01.015
PMCID:
PMC6469964
ArticlePDF–2.7M
11.
Identification of a Xist silencing domain by Tiling CRISPR
Yang Wang, Yang Zhong, Yingyao Zhou, Olga Tanaseichuk, Zhizhong Li, Jing Crystal Zhao
Sci Rep. 2019; 9: 2408. Published online 2019 Feb 20. doi: 10.1038/s41598-018-36750-0
PMCID:
PMC6382781
ArticlePDF–2.5M
12.
Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting
Orsolya Symmons, Marcello Chang, Ian A. Mellis, Jennifer M. Kalish, Jihwan Park, Katalin Suszták, Marisa S. Bartolomei, Arjun Raj
PLoS Genet. 2019 Jan; 15(1): e1007874. Published online 2019 Jan 9. doi: 10.1371/journal.pgen.1007874
PMCID:
PMC6342324
ArticlePDF–3.1M
13.
Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development
Shogo Matoba, Huihan Wang, Lan Jiang, Falong Lu, Kumiko A. Iwabuchi, Xiaoji Wu, Kimiko Inoue, Lin Yang, William Press, Jeannie T. Lee, Atsuo Ogura, Li Shen, Yi Zhang
Cell Stem Cell. Author manuscript; available in PMC 2019 Sep 6.
Published in final edited form as: Cell Stem Cell. 2018 Sep 6; 23(3): 343–354.e5. Published online 2018 Jul 19. doi: 10.1016/j.stem.2018.06.008
PMCID:
PMC6326833
ArticlePDF–1.2M
14.
Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males
Elsa J. Sousa, Hannah T. Stuart, Lawrence E. Bates, Mohammadmersad Ghorbani, Jennifer Nichols, Sabine Dietmann, José C.R. Silva
Cell Stem Cell. 2018 Jun 1; 22(6): 919–928.e6. doi: 10.1016/j.stem.2018.05.001
PMCID:
PMC5989057
ArticlePDF–3.2M
15.
A mixed modality approach towards Xi reactivation for Rett syndrome and other X-linked disorders
Lieselot L. G. Carrette, Chen-Yu Wang, Chunyao Wei, William Press, Weiyuan Ma, Raymond J. Kelleher, III, Jeannie T. Lee
Proc Natl Acad Sci U S A. 2018 Jan 23; 115(4): E668–E675. Published online 2017 Dec 27. doi: 10.1073/pnas.1715124115
PMCID:
PMC5789928
ArticlePDF–2.5M
16.
Genomic imprinting of Xist by maternal H3K27me3
Azusa Inoue, Lan Jiang, Falong Lu, Yi Zhang
Genes Dev. 2017 Oct 1; 31(19): 1927–1932. doi: 10.1101/gad.304113.117
PMCID:
PMC5710138
ArticlePDF–9.2M
17.
Allele-specific non-CG DNA methylation marks domains of active chromatin in female mouse brain
Christopher L. Keown, Joel B. Berletch, Rosa Castanon, Joseph R. Nery, Christine M. Disteche, Joseph R. Ecker, Eran A. Mukamel
Proc Natl Acad Sci U S A. 2017 Apr 4; 114(14): E2882–E2890. Published online 2017 Mar 20. doi: 10.1073/pnas.1611905114
PMCID:
PMC5389278
ArticlePDF–2.2M
18.
SHAPE reveals transcript-wide interactions, complex structural domains, and protein interactions across the Xist lncRNA in living cells
Matthew J. Smola, Thomas W. Christy, Kaoru Inoue, Cindo O. Nicholson, Matthew Friedersdorf, Jack D. Keene, David M. Lee, J. Mauro Calabrese, Kevin M. Weeks
Proc Natl Acad Sci U S A. 2016 Sep 13; 113(37): 10322–10327. Published online 2016 Aug 30. doi: 10.1073/pnas.1600008113
PMCID:
PMC5027438
ArticlePDF–11M
19.
Chromatin condensation of Xist genomic loci during oogenesis in mice
Atsushi Fukuda, Atsushi Mitani, Toshiyuki Miyashita, Akihiro Umezawa, Hidenori Akutsu
Development. 2015 Dec 1; 142(23): 4049–4055. doi: 10.1242/dev.127308
PMCID:
PMC4712840
Article
20.
The Xist RNA-PRC2 complex at 20-nm resolution reveals a low Xist stoichiometry and suggests a hit-and-run mechanism in mouse cells
Hongjae Sunwoo, John Y. Wu, Jeannie T. Lee
Proc Natl Acad Sci U S A. 2015 Aug 4; 112(31): E4216–E4225. Published online 2015 Jul 20. doi: 10.1073/pnas.1503690112
PMCID:
PMC4534268
ArticlePDF–2.5M

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