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Select item 104192271.

NR2F6, a new immune checkpoint that acts as a potential biomarker of immunosuppression and contributes to poor clinical outcome in human glioma

Hayat Miftah, Oumayma Naji, Saadia Ait Ssi, Amina Ghouzlani, Abdelhakim Lakhdar, Abdallah Badou

Front Immunol. 2023; 14: 1139268. Published online 2023 Jul 28. doi: 10.3389/fimmu.2023.1139268

PMCID:: PMC10419227

Article PDF–33M

Select item 103747212.

Overexpression of the orphan nuclear receptor NR2F6 is associated with improved survival across molecular subgroups in endometrial cancer patients

L. Proppe, T. Jagomast, S. Beume, L. Klapper, G. Gitas, F. Köster, S. Perner, A. Rody, J. Ribbat-Idel, L. C. Hanker

J Cancer Res Clin Oncol. 2023; 149(10): 7155–7164. Published online 2023 Mar 8. doi: 10.1007/s00432-023-04632-2

PMCID:: PMC10374721

Article PDF–1.1M

Select item 88066813.

Incomplete thermal ablation-induced up-regulation of transcription factor nuclear receptor subfamily 2, group F, member 6 (NR2F6) contributes to the rapid progression of residual liver tumor in hepatoblastoma

Jin-shu Pang, Dong-yue Wen, Rong-quan He, Gang Chen, Peng Lin, Jin-hong Li, Yu-jia Zhao, Lin-Yong Wu, Jun-Hong Chen, Yun He, Li-Ting Qin, Jia-bo Chen, Yong Li, Hong Yang

Bioengineered. 2021; 12(1): 4289–4303. Published online 2021 Jul 24. doi: 10.1080/21655979.2021.1945521

PMCID:: PMC8806681

Article PDF–2.6M

Select item 74323404.

NR2F6 as a Prognostic Biomarker in HNSCC

Luise Klapper, Julika Ribbat-Idel, Patrick Kuppler, Finn-Ole Paulsen, Karl-Ludwig Bruchhage, Dirk Rades, Anne Offermann, Jutta Kirfel, Barbara Wollenberg, Christian Idel, Sven Perner

Int J Mol Sci. 2020 Aug; 21(15): 5527. Published online 2020 Aug 1. doi: 10.3390/ijms21155527

PMCID:: PMC7432340

Article PDF–5.4M

Select item 67677855.

Nuclear orphan receptor NR2F6 confers cisplatin resistance in epithelial ovarian cancer cells by activating the Notch3 signaling pathway

Han Li, Weijing Zhang, Chunhao Niu, Chuyong Lin, Xianqiu Wu, Yunting Jian, Yue Li, Liping Ye, Yuhu Dai, Ying Ouyang, Jueming Chen, Jiaqi Qiu, Libing Song, Yanna Zhang

Int J Cancer. 2019 Oct 1; 145(7): 1921–1934. Published online 2019 Apr 4. doi: 10.1002/ijc.32293

PMCID:: PMC6767785

Article PDF–9.6M

Select item 50857266.

NR2F6 Expression Correlates with Pelvic Lymph Node Metastasis and Poor Prognosis in Early-Stage Cervical Cancer

Chunhao Niu, Xiaoying Sun, Weijing Zhang, Han Li, Liqun Xu, Jun Li, Benke Xu, Yanna Zhang

Int J Mol Sci. 2016 Oct; 17(10): 1694. Published online 2016 Oct 20. doi: 10.3390/ijms17101694

PMCID:: PMC5085726

Article PDF–4.0M

Select item 66399397.

Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression

Liyan Wang, Haiyan Long, Qinghua Zheng, Xiaotong Bo, Xuhua Xiao, Bin Li

Mol Cancer. 2019; 18: 119. Published online 2019 Jul 19. doi: 10.1186/s12943-019-1046-7

PMCID:: PMC6639939

Article PDF–5.6M

Select item 59066048.

Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade

Victoria Klepsch, Natascha Hermann-Kleiter, Patricia Do-Dinh, Bojana Jakic, Anne Offermann, Mirjana Efremova, Sieghart Sopper, Dietmar Rieder, Anne Krogsdam, Gabriele Gamerith, Sven Perner, Alexandar Tzankov, Zlatko Trajanoski, Dominik Wolf, Gottfried Baier

Nat Commun. 2018; 9: 1538. Published online 2018 Apr 18. doi: 10.1038/s41467-018-04004-2

PMCID:: PMC5906604

Article PDF–1.8M

Select item 56684889.

Association between polymorphisms in microRNA target sites and survival in early‐stage non‐small cell lung cancer

Seung Soo Yoo, Mi Jeong Hong, Jang Hyuck Lee, Jin Eun Choi, Shin Yup Lee, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Yangki Seok, Eungbae Lee, Sukki Cho, Sanghoon Jheon, Jae Yong Park

Thorac Cancer. 2017 Nov; 8(6): 682–686. Published online 2017 Sep 18. doi: 10.1111/1759-7714.12478

PMCID:: PMC5668488

Article PDF–232K

Select item 33899610.

Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other.

N Miyajima, Y Kadowaki, S Fukushige, S Shimizu, K Semba, Y Yamanashi, K Matsubara, K Toyoshima, T Yamamoto

Nucleic Acids Res. 1988 Dec 9; 16(23): 11057–11074. doi: 10.1093/nar/16.23.11057

PMCID:: PMC338996

Summary Page Browse PDF–1.6M

Select item 282325411.

Heterodimeric Interactions between Chicken Ovalbumin Upstream Promoter-Transcription Factor Family Members ARP1 and Ear2

Dorina Avram, Jane E. Ishmael, Daniel J. Nevrivy, Valerie J. Peterson, Suk-Hyung Lee, Paul Dowell, Mark Leid

J Biol Chem. Author manuscript; available in PMC 2010 Feb 17.

Published in final edited form as: J Biol Chem. 1999 May 14; 274(20): 14331. doi: 10.1074/jbc.274.20.14331

PMCID:: PMC2823254

Article PDF–648K

Select item 8547612.

The Orphan Nuclear Receptor Ear-2 Is a Negative Coregulator for Thyroid Hormone Nuclear Receptor Function

Xu-guang Zhu, Kyung Soo Park, Masahiro Kaneshige, Manoj K. Bhat, Qihong Zhu, Cary N. Mariash, Peter McPhie, Sheue-yann Cheng

Mol Cell Biol. 2000 Apr; 20(7): 2604–2618. doi: 10.1128/mcb.20.7.2604-2618.2000

PMCID:: PMC85476

Article PDF–2.3M

Select item 303662113.

Rasd1 interacts with Ear2 (Nr2f6) to regulate renin transcription

Jen Jen Tan, Shufen Angeline Ong, Ken-Shiung Chen

BMC Mol Biol. 2011; 12: 4. Published online 2011 Jan 19. doi: 10.1186/1471-2199-12-4

PMCID:: PMC3036621

Article PDF–1.9M

Select item 383482914.

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors

Chun Ming Chan, Joel Fulton, Cristina Montiel-Duarte, Hilary M. Collins, Neetu Bharti, Frances R. Wadelin, Paula M. Moran, Nigel P. Mongan, David M. Heery

Nucleic Acids Res. 2013 Nov; 41(21): 9663–9679. Published online 2013 Aug 23. doi: 10.1093/nar/gkt761

PMCID:: PMC3834829

Article PDF–3.7M

Select item 274243515.

Complementary Quantitative Proteomics Reveals that Transcription Factor AP-4 Mediates E-box-dependent Complex Formation for Transcriptional Repression of HDM2

Wei-Chi Ku, Sung-Kay Chiu, Yi-Ju Chen, Hsin-Hung Huang, Wen-Guey Wu, Yu-Ju Chen

Mol Cell Proteomics. 2009 Sep; 8(9): 2034–2050. Published online 2009 Jun 7. doi: 10.1074/mcp.M900013-MCP200

PMCID:: PMC2742435

Article PDF–560K

Select item 282753816.

A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks

Etsuko Miyamoto-Sato, Shigeo Fujimori, Masamichi Ishizaka, Naoya Hirai, Kazuyo Masuoka, Rintaro Saito, Yosuke Ozawa, Katsuya Hino, Takanori Washio, Masaru Tomita, Tatsuhiro Yamashita, Tomohiro Oshikubo, Hidetoshi Akasaka, Jun Sugiyama, Yasuo Matsumoto, Hiroshi Yanagawa

PLoS One. 2010; 5(2): e9289. Published online 2010 Feb 24. doi: 10.1371/journal.pone.0009289

PMCID:: PMC2827538

Article PDF–676K

Select item 913694317.

Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

Bhaskar Saha, Michelle Salemi, Geneva L. Williams, Seeun Oh, Michael L. Paffett, Brett Phinney, Michael A. Mandell

Cell Rep. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110797. doi: 10.1016/j.celrep.2022.110797

PMCID:: PMC9136943

Article PDF–3.2M

Select item 800904818.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239