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Select item 99388601.

Urokinase-type plasminogen activator blockade ameliorates experimental colitis in mice

Yoshifumi Kida, Toshiya Okahisa, Yasushi Sato, Masahiro Bando, Shota Fujimoto, Beibei Ma, Tadahiko Nakagawa, Tomoyuki Kawaguchi, Fumika Nakamura, Koichi Okamoto, Hiroshi Miyamoto, Masahiro Sogabe, Koichi Tsuneyama, Tetsuji Takayama

Sci Rep. 2023; 13: 2899. Published online 2023 Feb 18. doi: 10.1038/s41598-023-29824-1

PMCID:: PMC9938860

Article PDF–2.0M

Select item 98671692.

Urokinase System in Pathogenesis of Pulmonary Fibrosis: A Hidden Threat of COVID-19

Anna A. Shmakova, Vladimir S. Popov, Iliya P. Romanov, Nikita R. Khabibullin, Nailya R. Sabitova, Anna A. Karpukhina, Yana A. Kozhevnikova, Ella V. Kurilina, Zoya I. Tsokolaeva, Polina S. Klimovich, Kseniya A. Rubina, Yegor S. Vassetzky, Ekaterina V. Semina

Int J Mol Sci. 2023 Jan; 24(2): 1382. Published online 2023 Jan 10. doi: 10.3390/ijms24021382

PMCID:: PMC9867169

Article PDF–3.8M

Select item 70114013.

Urokinase Plasminogen Activator Overexpression Reverses Established Lung Fibrosis

Jeffrey C. Horowitz, Daniel J. Tschumperlin, Kevin K. Kim, John J. Osterholzer, Natalya Subbotina, Iyabode O. Ajayi, Seagal Teitz-Tennenbaum, Ammara Virk, Megan Dotson, Fei Liu, Delphine Sicard, Shijing Jia, Thomas H. Sisson

Thromb Haemost. Author manuscript; available in PMC 2020 Feb 11.

Published in final edited form as: Thromb Haemost. 2019 Dec; 119(12): 1968–1980. Published online 2019 Nov 8. doi: 10.1055/s-0039-1697953

PMCID:: PMC7011401

Article PDF–1.6M

Select item 69305344.

Deficiency of Urokinase Plasminogen Activator May Impair β Cells Regeneration and Insulin Secretion in Type 2 Diabetes Mellitus

Chung-Ze Wu, Shih-Hsiang Ou, Li-Chien Chang, Yuh-Feng Lin, Dee Pei, Jin-Shuen Chen

Molecules. 2019 Dec; 24(23): 4208. Published online 2019 Nov 20. doi: 10.3390/molecules24234208

PMCID:: PMC6930534

Article PDF–3.6M

Select item 58053425.

Ligand binding modulates the structural dynamics and activity of urokinase-type plasminogen activator: A possible mechanism of plasminogen activation

Tobias Kromann-Hansen, Eva Louise Lange, Ida K. Lund, Gunilla Høyer-Hansen, Peter A. Andreasen, Elizabeth A. Komives

PLoS One. 2018; 13(2): e0192661. Published online 2018 Feb 8. doi: 10.1371/journal.pone.0192661

PMCID:: PMC5805342

Article PDF–7.5M

Select item 43947286.

Wound healing and longevity: Lessons from long-lived αMUPA mice

Hagai Yanai, Dimitri Toren, Klemens Vierlinger, Manuela Hofner, Christa Nöhammer, Marco Chilosi, Arie Budovsky, Vadim E. Fraifeld

Aging (Albany NY) 2015 Mar; 7(3): 167–176. Published online 2015 Feb 24. doi: 10.18632/aging.100726

Correction in:: Aging (Albany NY). 2016 Mar; 8(3): 564.

PMCID:: PMC4394728

Article PDF–1.4M

Select item 42003897.

Regulation of epithelial sodium channels in urokinase plasminogen activator deficiency

Zaixing Chen, Runzhen Zhao, Meimi Zhao, Xinrong Liang, Deepa Bhattarai, Rohan Dhiman, Sreerama Shetty, Steven Idell, Hong-Long Ji

Am J Physiol Lung Cell Mol Physiol. 2014 Oct 15; 307(8): L609–L617. Published online 2014 Aug 29. doi: 10.1152/ajplung.00126.2014

PMCID:: PMC4200389

Article

Select item 41012958.

Urokinase-Type Plasminogen Activator Deficiency Promotes Neoplasmatogenesis in the Colon of Mice

Elisavet Karamanavi, Katerina Angelopoulou, Sophia Lavrentiadou, Anastasia Tsingotjidou, Zaphiris Abas, Ioannis Taitzoglou, Ioannis Vlemmas, Suzan E. Erdman, Theofilos Poutahidis

Transl Oncol. 2014 Apr; 7(2): 174–187.e5. Published online 2014 Mar 4. doi: 10.1016/j.tranon.2014.02.002

PMCID:: PMC4101295

Article PDF–6.8M

Select item 33375649.

Over-expression of uPA increases risk of liver injury in pAAV-HBV transfected mice

Xiao-Jun Zhou, Shi-Hui Sun, Peng Wang, Hong Yu, Jing-Ya Hu, Shi-Cheng Shang, Yu-Sen Zhou

World J Gastroenterol. 2012 Apr 28; 18(16): 1892–1902. Published online 2012 Apr 28. doi: 10.3748/wjg.v18.i16.1892

PMCID:: PMC3337564

Article PDF–1.1M

Select item 326268310.

Urokinase Plasminogen Activator Regulates Pulmonary Arterial Contractility and Vascular Permeability in Mice

Taher Nassar, Serge Yarovoi, Rami Abu Fanne, Otailah Waked, Timothy C. Allen, Steven Idell, Douglas B. Cines, Abd Al-Roof Higazi

Am J Respir Cell Mol Biol. 2011 Nov; 45(5): 1015–1021. doi: 10.1165/rcmb.2010-0302OC

PMCID:: PMC3262683

Article PDF–762K

Select item 288818411.

Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvement

Andrew D Cook, Christine M De Nardo, Emma L Braine, Amanda L Turner, Ross Vlahos, Kerrie J Way, S Kaye Beckman, Jason C Lenzo, John A Hamilton

Arthritis Res Ther. 2010; 12(2): R37. Published online 2010 Mar 2. doi: 10.1186/ar2946

PMCID:: PMC2888184

Article PDF–6.4M

Select item 188575912.

Hepatocyte Transplantation into Diseased Mouse Liver : Kinetics of Parenchymal Repopulation and Identification of the Proliferative Capacity of Tetraploid and Octaploid Hepatocytes

Teresa C. Weglarz, Jay L. Degen, Eric P. Sandgren

Am J Pathol. 2000 Dec; 157(6): 1963–1974. doi: 10.1016/S0002-9440(10)64835-3

PMCID:: PMC1885759

Article PDF–545K

Select item 185853613.

Urokinase-type plasminogen activator-deficient mice are predisposed to staphylococcal botryomycosis, pleuritis, and effacement of lymphoid follicles.

R. L. Shapiro, J. G. Duquette, I. Nunes, D. F. Roses, M. N. Harris, E. L. Wilson, D. B. Rifkin

Am J Pathol. 1997 Jan; 150(1): 359–369.

PMCID:: PMC1858536

Summary Page Browse PDF–4.8M

Select item 146837114.

The pathophysiology of pelvic floor disorders: evidence from a histomorphologic study of the perineum and a mouse model of rectal prolapse

RENÉ YIOU, VINCENT DELMAS, PETER CARMELIET, ROMAIN K. GHERARDI, GEORGIA BARLOVATZ-MEIMON, DOMINIQUE K. CHOPIN, CLÉMENT-CLAUDE ABBOU, JEAN-PASCAL LEFAUCHEUR

J Anat. 2001 Nov; 199(Pt 5): 599–607. doi: 10.1046/j.1469-7580.2001.19950599.x