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Select item 107654951.

Blocking P2Y2 purinergic receptor prevents the development of lipopolysaccharide-induced acute respiratory distress syndrome

Zahra Kargarpour, Sanja Cicko, Thomas C. Köhler, Andreas Zech, Slagjana Stoshikj, Christina Bal, Andreas Renner, Marco Idzko, Ahmed El-Gazzar

Front Immunol. 2023; 14: 1310098. Published online 2023 Dec 20. doi: 10.3389/fimmu.2023.1310098

PMCID:: PMC10765495

Article PDF–4.5M

Select item 105430842.

Cell-type-specific role of P2Y2 receptor in HDM-driven model of allergic airway inflammation

Dominik Schneble, Ahmed El-Gazzar, Zahra Kargarpour, Markus Kramer, Seda Metekol, Slagjana Stoshikj, Marco Idzko

Front Immunol. 2023; 14: 1209097. Published online 2023 Sep 14. doi: 10.3389/fimmu.2023.1209097

PMCID:: PMC10543084

Article PDF–7.0M

Select item 104944563.

Sex-specific effect of P2Y₂ purinergic receptor on glucose metabolism during acute inflammation

Randi J. Ulbricht, Christian A. Rivas, Hailee Marino, Erin Snyder, Dana James, Jamila Makhloufi, Nathan Johnson, Scott Zimmerman, Jianjie Wang

Front Endocrinol (Lausanne) 2023; 14: 1248139. Published online 2023 Aug 28. doi: 10.3389/fendo.2023.1248139

PMCID:: PMC10494456

Article PDF–1.4M

Select item 102913294.

A purinergic mechanism underlying metformin regulation of hyperglycemia

Jared Senfeld, Qianman Peng, Yi Shi, Shenqi Qian, Jianzhong Shen

iScience. 2023 Jun 16; 26(6): 106898. Published online 2023 May 19. doi: 10.1016/j.isci.2023.106898

PMCID:: PMC10291329

Article PDF–4.7M

Select item 83595955.

P2Y2 promotes fibroblasts activation and skeletal muscle fibrosis through AKT, ERK, and PKC

Mengjie Chen, Haibing Chen, Yonggui Gu, Peng Sun, Jianxiong Sun, Haojun Yu, Hongliang Zheng, Donghui Chen

BMC Musculoskelet Disord. 2021; 22: 680. Published online 2021 Aug 11. doi: 10.1186/s12891-021-04569-y

PMCID:: PMC8359595

Article PDF–7.8M

Select item 81971976.

P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice

Theodomir Dusabimana, Eun Jung Park, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park

Int J Mol Sci. 2021 Jun; 22(11): 5528. Published online 2021 May 24. doi: 10.3390/ijms22115528

PMCID:: PMC8197197

Article PDF–3.3M

Select item 75681857.

P2Y2R contributes to the development of diabetic nephropathy by inhibiting autophagy response

Theodomir Dusabimana, So Ra Kim, Eun Jung Park, Jihyun Je, Kyuho Jeong, Seung Pil Yun, Hye Jung Kim, Hwajin Kim, Sang Won Park

Mol Metab. 2020 Dec; 42: 101089. Published online 2020 Sep 25. doi: 10.1016/j.molmet.2020.101089

PMCID:: PMC7568185

Article PDF–4.1M

Select item 72838748.

P2Y₂ Receptor Promotes High-Fat Diet-Induced Obesity

Yue Zhang, Carolyn M. Ecelbarger, Lisa A. Lesniewski, Christa E. Müller, Bellamkonda K. Kishore

Front Endocrinol (Lausanne) 2020; 11: 341. Published online 2020 Jun 3. doi: 10.3389/fendo.2020.00341

PMCID:: PMC7283874

Article PDF–2.1M

Select item 66440539.

P2Y₂R deletion ameliorates sialadenitis in IL-14α-transgenic mice

LT Woods, JM Camden, MG Khalafalla, MJ Petris, L Erb, JL Ambrus, Jr, GA Weisman

Oral Dis. Author manuscript; available in PMC 2019 Jul 22.

Published in final edited form as: Oral Dis. 2018 Jul; 24(5): 761–771. Published online 2018 Mar 13. doi: 10.1111/odi.12823

PMCID:: PMC6644053

Article PDF–1.4M

Select item 630435410.

Genetic Deletion of P2Y₂ Receptor Offers Long-Term (5 Months) Protection Against Lithium-Induced Polyuria, Natriuresis, Kaliuresis, and Collecting Duct Remodeling and Cell Proliferation

Yue Zhang, Anne Riquier-Brison, Tao Liu, Yufeng Huang, Noel G. Carlson, János Peti-Peterdi, Bellamkonda K. Kishore

Front Physiol. 2018; 9: 1765. Published online 2018 Dec 17. doi: 10.3389/fphys.2018.01765

PMCID:: PMC6304354

Article PDF–3.7M

Select item 584215011.

Myeloid P2Y2 receptor promotes acute inflammation but is dispensable for chronic high-fat diet-induced metabolic dysfunction

Samantha E. Adamson, Garren Montgomery, Scott A. Seaman, Shayn M. Peirce-Cottler, Norbert Leitinger

Purinergic Signal. 2018 Mar; 14(1): 19–26. Published online 2017 Oct 30. doi: 10.1007/s11302-017-9589-9

PMCID:: PMC5842150

Article PDF–1.1M

Select item 549759812.

DELETION OF THE MURINE ATP/UTP RECEPTOR P2Y₂ ALTERS MECHANICAL AND THERMAL RESPONSE PROPERTIES IN POLYMODAL CUTANEOUS AFFERENTS

DEREK C. MOLLIVER, KRISTOFER K. RAU, MICHAEL P. JANKOWSKI, DEEPAK J. SONEJI, KYLE M. BAUMBAUER, H. RICHARD KOERBER

Neuroscience. Author manuscript; available in PMC 2017 Sep 22.

Published in final edited form as: Neuroscience. 2016 Sep 22; 332: 223–230. Published online 2016 Jul 5. doi: 10.1016/j.neuroscience.2016.06.054

PMCID:: PMC5497598

Article PDF–1.0M

Select item 537394313.

AUGMENTATION OF MUSCLE BLOOD FLOW BY ULTRASOUND CAVITATION IS MEDIATED BY ATP AND PURINERGIC SIGNALING

J. Todd Belcik, Brian P. Davidson, Aris Xie, Melinda D. Wu, Mrinal Yadava, Yue Qi, Sherry Liang, Chae Ryung Chon, Azzdine Y. Ammi, Joshua Field, Leanne Harmann, William M. Chilian, Joel Linden, Jonathan R. Lindner

Circulation. Author manuscript; available in PMC 2018 Mar 28.

Published in final edited form as: Circulation. 2017 Mar 28; 135(13): 1240–1252. Published online 2017 Feb 7. doi: 10.1161/CIRCULATIONAHA.116.024826

PMCID:: PMC5373943

Article PDF–1.2M

Select item 512400914.

P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells

Andre Kraus, Steffen Grampp, Margarete Goppelt-Struebe, Rainer Schreiber, Karl Kunzelmann, Dorien J.M. Peters, Jens Leipziger, Gunnar Schley, Johannes Schödel, Kai-Uwe Eckardt, Bjoern Buchholz

Purinergic Signal. 2016 Dec; 12(4): 687–695. Published online 2016 Aug 26. doi: 10.1007/s11302-016-9532-5

PMCID:: PMC5124009

Article PDF–1.9M

Select item 459672715.

Attenuation of lithium-induced natriuresis and kaliuresis in P2Y₂ receptor knockout mice

Yue Zhang, Lijun Li, Donald E. Kohan, Carolyn M. Ecelbarger, Bellamkonda K. Kishore

Am J Physiol Renal Physiol. 2013 Aug 1; 305(3): F407–F416. Published online 2013 Jun 5. doi: 10.1152/ajprenal.00464.2012

PMCID:: PMC4596727

Article

Select item 450554216.

[Ca²⁺]_i Oscillations and IL-6 Release Induced by α-Hemolysin from Escherichia coli Require P2 Receptor Activation in Renal Epithelia

Mette G. Christensen, Steen K. Fagerberg, Pauline I. de Bruijn, Randi G. Bjaelde, Helle Jakobsen, Jens Leipziger, Marianne Skals, Helle A. Praetorius

J Biol Chem. 2015 Jun 5; 290(23): 14776–14784. Published online 2015 Apr 24. doi: 10.1074/jbc.M115.639526

PMCID:: PMC4505542

Article PDF–2.0M

Select item 433422117.

P2Y₂R Deficiency Attenuates Experimental Autoimmune Uveitis Development

Lia Judice M. Relvas, Maya Makhoul, Remi Dewispelaere, Laure Caspers, Didier Communi, Jean-Marie Boeynaems, Bernard Robaye, Catherine Bruyns, François Willermain

PLoS One. 2015; 10(2): e0116518. Published online 2015 Feb 18. doi: 10.1371/journal.pone.0116518

PMCID:: PMC4334221

Article PDF–1.9M

Select item 431254418.

P2Y₂ Nucleotide Receptor Mediates Arteriogenesis in a Murine Model of Hindlimb Ischemia

Ryan M. McEnaney, Ankur Shukla, Michael C. Madigan, Ulka Sachdev, Edith Tzeng

J Vasc Surg. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: J Vasc Surg. 2016 Jan; 63(1): 216–225. Published online 2014 Jul 31. doi: 10.1016/j.jvs.2014.06.112

PMCID:: PMC4312544

Article PDF–768K

Select item 425496019.

P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy

Bryan C. Tackett, Hongdan Sun, Yu Mei, Janielle P. Maynard, Sayuri Cheruvu, Arunmani Mani, Andres Hernandez-Garcia, Nadarajah Vigneswaran, Saul J. Karpen, Sundararajah Thevananther

Am J Physiol Gastrointest Liver Physiol. 2014 Dec 1; 307(11): G1073–G1087. Published online 2014 Oct 9. doi: 10.1152/ajpgi.00092.2014