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Select item 97468981.

Intestinal epithelial BLT1 promotes mucosal repair

Shusaku Hayashi, Chithra K. Muraleedharan, Makito Oku, Sunil Tomar, Simon P. Hogan, Miguel Quiros, Charles A. Parkos, Asma Nusrat

JCI Insight. 2022 Dec 8; 7(23): e162392. Published online 2022 Dec 8. doi: 10.1172/jci.insight.162392

PMCID:: PMC9746898

Article PDF–2.5M

Select item 63949742.

Role of the high-affinity leukotriene B₄ receptor signaling in fibrosis after unilateral ureteral obstruction in mice

Mariko Kamata, Hideki Amano, Yoshiya Ito, Tomoe Fujita, Fumisato Otaka, Kanako Hosono, Kouju Kamata, Yasuo Takeuchi, Takehiko Yokomizo, Takao Shimizu, Masataka Majima

PLoS One. 2019; 14(2): e0202842. Published online 2019 Feb 28. doi: 10.1371/journal.pone.0202842

Correction in:: PLoS One. 2019; 14(4): e0215625.

PMCID:: PMC6394974

Article PDF–2.5M

Select item 62695243.

BLT1 in dendritic cells promotes Th1/Th17 differentiation and its deficiency ameliorates TNBS-induced colitis

Jinfeng Zhou, Weiming Lai, Wanjie Yang, Juping Pan, Hu Shen, Yingying Cai, Cuixia Yang, Ningjia Ma, Yue Zhang, Ru Zhang, Xin Xie, Zhongjun Dong, Yuan Gao, Changsheng Du

Cell Mol Immunol. 2018 Dec; 15(12): 1047–1056. Published online 2018 Apr 18. doi: 10.1038/s41423-018-0030-2

PMCID:: PMC6269524

Article PDF–2.0M

Select item 51733894.

Critical role of LTB4/BLT1 in IL-23 induced synovial inflammation and osteoclastogenesis via NF-κB

Laura Bouchareychas, Eva M Grössinger, Mincheol Kang, Hong Qiu, Iannis E Adamopoulos

J Immunol. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: J Immunol. 2017 Jan 1; 198(1): 452–460. Published online 2016 Nov 28. doi: 10.4049/jimmunol.1601346

PMCID:: PMC5173389

Article PDF–1.8M

Select item 49396025.

BLT₁ signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils

Ken Kojo, Yoshiya Ito, Koji Eshima, Nobuyuki Nishizawa, Hirotoki Ohkubo, Takehiko Yokomizo, Takao Shimizu, Masahiko Watanabe, Masataka Majima

Sci Rep. 2016; 6: 29650. Published online 2016 Jul 11. doi: 10.1038/srep29650

PMCID:: PMC4939602

Article PDF–2.3M

Select item 46120996.

Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses

Yu Sawada, Tetsuya Honda, Sho Hanakawa, Satoshi Nakamizo, Teruasa Murata, Yuri Ueharaguchi-Tanada, Sachiko Ono, Wataru Amano, Saeko Nakajima, Gyohei Egawa, Hideaki Tanizaki, Atsushi Otsuka, Akihiko Kitoh, Teruki Dainichi, Narihito Ogawa, Yuichi Kobayashi, Takehiko Yokomizo, Makoto Arita, Motonobu Nakamura, Yoshiki Miyachi, Kenji Kabashima

J Exp Med. 2015 Oct 19; 212(11): 1921–1930. doi: 10.1084/jem.20150381

PMCID:: PMC4612099

Article PDF–2.3M

Select item 45525007.

Leukotriene B₄—leukotriene B₄ receptor axis promotes oxazolone-induced contact dermatitis by directing skin homing of neutrophils and CD8⁺ T cells

Jiaoyan Lv, Linlin Zou, Lina Zhao, Wei Yang, Yingluo Xiong, Bingji Li, Rui He

Immunology. 2015 Sep; 146(1): 50–58. Published online 2015 Jun 29. doi: 10.1111/imm.12478

PMCID:: PMC4552500

Article PDF–884K

Select item 44297988.

LTB4 causes macrophage–mediated inflammation and directly induces insulin resistance in obesity

Pingping Li, Da Young Oh, Gautam Bandyopadhyay, William S. Lagakos, Saswata Talukdar, Olivia Osborn, Andrew Johnson, Heekyung Chung, Michael Maris, Jachelle M. Ofrecio, Sayaka Taguchi, Min Lu, Jerrold M. Olefsky

Nat Med. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Nat Med. 2015 Mar; 21(3): 239–247. Published online 2015 Feb 23. doi: 10.1038/nm.3800

PMCID:: PMC4429798

Article PDF–1.2M

Select item 43630559.

The absence of the leukotriene B₄ receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury

Miho Asahara, Nobuko Ito, Takehiko Yokomizo, Motonao Nakamura, Takao Shimizu, Yoshitsugu Yamada

Mol Pain. 2015; 11: 11. Published online 2015 Mar 12. doi: 10.1186/s12990-015-0010-9

PMCID:: PMC4363055

Article PDF–1.2M

Select item 405764610.

Leukotriene B₄ mediates γδ T lymphocyte migration in response to diverse stimuli

Maria Fernanda de Souza Costa, Raquel de Souza-Martins, Mariana C. de Souza, Cláudia F. Benjamim, Bruno Piva, Bruno L. Diaz, Marc Peters-Golden, Maria das Graças Henriques, Cláudio Canetti, Carmen Penido

J Leukoc Biol. 2010 Feb; 87(2): 323–332. Published online 2009 Oct 30. doi: 10.1189/jlb.0809563

PMCID:: PMC4057646

Article

Select item 389741911.

The Leukotriene B₄/BLT₁ Axis Is a Key Determinant in Susceptibility and Resistance to Histoplasmosis

Adriana Secatto, Elyara Maria Soares, Gisele Aparecida Locachevic, Patricia Aparecida Assis, Francisco Wanderlei Garcia Paula-Silva, Carlos Henrique Serezani, Alexandra Ivo de Medeiros, Lúcia Helena Faccioli

PLoS One. 2014; 9(1): e85083. Published online 2014 Jan 21. doi: 10.1371/journal.pone.0085083

PMCID:: PMC3897419

Article PDF–666K

Select item 375107512.

Critical role of leukotriene B₄ receptor signaling in mouse 3T3-L1 preadipocyte differentiation

Kae Hirata, Koichiro Wada, Yuka Murata, Atsushi Nakajima, Takashi Yamashiro, Yoshinori Kamisaki

Lipids Health Dis. 2013; 12: 122. Published online 2013 Aug 9. doi: 10.1186/1476-511X-12-122

PMCID:: PMC3751075

Article PDF–1.8M

Select item 320861013.

Blocking the Leukotriene B4 Receptor 1 Inhibits Late-Phase Airway Responses in Established Disease

Koichi Waseda, Nobuaki Miyahara, Arihiko Kanehiro, Genyo Ikeda, Hikari Koga, Yasuko Fuchimoto, Etsuko Kurimoto, Yasushi Tanimoto, Mikio Kataoka, Mitsune Tanimoto, Erwin W. Gelfand

Am J Respir Cell Mol Biol. 2011 Oct; 45(4): 851–857. Published online 2011 Mar 18. doi: 10.1165/rcmb.2010-0455OC

PMCID:: PMC3208610

Article PDF–739K

Select item 315035314.

Deficiency of the leukotriene B₄ receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity

Matthew Spite, Jason Hellmann, Yunan Tang, Steven P. Mathis, Madhavi Kosuri, Aruni Bhatnagar, Venkatakrishna R. Jala, Bodduluri Haribabu

J Immunol. Author manuscript; available in PMC 2012 Aug 15.

Published in final edited form as: J Immunol. 2011 Aug 15; 187(4): 1942–1949. Published online 2011 Jul 8. doi: 10.4049/jimmunol.1100196

PMCID:: PMC3150353

Article PDF–1.5M

Select item 286110015.

The LTB4-BLT1 Axis Mediates Neutrophil Infiltration and Secondary Injury in Experimental Spinal Cord Injury

Hirokazu Saiwai, Yasuyuki Ohkawa, Hisakata Yamada, Hiromi Kumamaru, Akihito Harada, Hideyuki Okano, Takehiko Yokomizo, Yukihide Iwamoto, Seiji Okada

Am J Pathol. 2010 May; 176(5): 2352–2366. doi: 10.2353/ajpath.2010.090839

PMCID:: PMC2861100

Article PDF–1.6M

Select item 279550316.

A distinctive role of the leukotriene B₄ receptor BLT1 in osteoclastic activity during bone loss

Hisako Hikiji, Satoshi Ishii, Takehiko Yokomizo, Tsuyoshi Takato, Takao Shimizu

Proc Natl Acad Sci U S A. 2009 Dec 15; 106(50): 21294–21299. Published online 2009 Nov 24. doi: 10.1073/pnas.0905209106

PMCID:: PMC2795503

Article PDF–1.7M

Select item 271846517.

Requirement for Leukotriene B₄ Receptor 1 in Allergen-induced Airway Hyperresponsiveness

Nobuaki Miyahara, Katsuyuki Takeda, Satoko Miyahara, Shigeki Matsubara, Toshiyuki Koya, Anthony Joetham, Elangovan Krishnan, Azzeddine Dakhama, Bodduluri Haribabu, Erwin W. Gelfand

Am J Respir Crit Care Med. 2005 Jul 15; 172(2): 161–167. Published online 2005 Apr 22. doi: 10.1164/rccm.200502-205OC

PMCID:: PMC2718465

Article PDF–516K

Select item 221289118.

BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation

Benjamin D. Medoff, Edward Seung, John C. Wain, Terry K. Means, Gabriele S.V. Campanella, Sabina A. Islam, Seddon Y. Thomas, Leo C. Ginns, Nir Grabie, Andrew H. Lichtman, Andrew M. Tager, Andrew D. Luster

J Exp Med. 2005 Jul 4; 202(1): 97–110. doi: 10.1084/jem.20042481