PMC Links for Gene (Select 15530) - PMC

Ashutosh Parajuli, Shaopeng Pei, Hongbo Zhao, Jerahme R. Martinez, X. Lucas Lu, X. Sherry Liu, Mary C. Farach-Carson, Catherine B. Kirn-Safran, Liyun Wang

Biomolecules. 2020 Feb; 10(2): 198. Published online 2020 Jan 29. doi: 10.3390/biom10020198

PMCID:: PMC7072656

Article PDF–2.2M

Select item 69459814.

Perlecan/Hspg2 deficiency impairs bone’s calcium signaling and associated transcriptome in response to mechanical loading

Shaopeng Pei, Sucharitha Parthasarathy, Ashutosh Parajuli, Jerahme Martinez, Mengxi Lv, Sida Jiang, Danielle Wu, Shuo Wei, X. Lucas Lu, Mary C. Farach-Carson, Catherine B. Kirn-Safran, Liyun Wang

Bone. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Bone. 2020 Feb; 131: 115078. Published online 2019 Nov 9. doi: 10.1016/j.bone.2019.115078

PMCID:: PMC6945981

Article PDF–1.9M

Select item 60562655.

Achilles and tail tendons of perlecan exon 3 null heparan sulphate deficient mice display surprising improvement in tendon tensile properties and altered collagen fibril organisation compared to C57BL/6 wild type mice

Cindy C. Shu, Margaret M. Smith, Richard C. Appleyard, Christopher B. Little, James Melrose

PeerJ. 2018; 6: e5120. Published online 2018 Jun 29. doi: 10.7717/peerj.5120

PMCID:: PMC6056265

Article PDF–6.1M

Select item 59581006.

Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle

Yuri Yamashita, Satoshi Nakada, Toshinori Yoshihara, Takeshi Nara, Norihiko Furuya, Takashi Miida, Nobutaka Hattori, Eri Arikawa-Hirasawa

Sci Rep. 2018; 8: 7766. Published online 2018 May 17. doi: 10.1038/s41598-018-25635-x

PMCID:: PMC5958100

Article PDF–6.6M

Select item 56913317.

A Mouse Model of Schwartz-Jampel Syndrome Reveals Myelinating Schwann Cell Dysfunction with Persistent Axonal Depolarization in Vitro and Distal Peripheral Nerve Hyperexcitability When Perlecan Is Lacking

Marie Bangratz, Nadège Sarrazin, Jérôme Devaux, Désirée Zambroni, Andoni Echaniz-Laguna, Frédérique René, Delphine Boërio, Claire-Sophie Davoine, Bertrand Fontaine, Maria Laura Feltri, Evelyne Benoit, Sophie Nicole

Am J Pathol. 2012 May; 180(5): 2040–2055. doi: 10.1016/j.ajpath.2012.01.035

PMCID:: PMC5691331

Article PDF–3.6M

Select item 50709718.

Knockdown of the pericellular matrix molecule perlecan lowers in situ cell and matrix stiffness in developing cartilage

Xin Xu, Zhiyu Li, Yue Leng, Corey P. Neu, Sarah Calve

Dev Biol. Author manuscript; available in PMC 2017 Oct 15.

Published in final edited form as: Dev Biol. 2016 Oct 15; 418(2): 242–247. Published online 2016 Aug 27. doi: 10.1016/j.ydbio.2016.08.029

PMCID:: PMC5070971

Article PDF–920K

Select item 41375669.

Deficiency in Perlecan/HSPG2 during Bone Development Enhances Osteogenesis and Decreases Quality of Adult Bone in Mice

Dylan A. Lowe, Nadia Lepori-Bui, Peter V. Fomin, Laura G. Sloofman, Xiaozhou Zhou, Mary C. Farach-Carson, Liyun Wang, Catherine B. Kirn-Safran

Calcif Tissue Int. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Calcif Tissue Int. 2014 Jul; 95(1): 29–38. Published online 2014 May 6. doi: 10.1007/s00223-014-9859-2

PMCID:: PMC4137566

Article PDF–1.0M

Select item 396251910.

Perlecan-containing pericellular matrix regulates solute transport and mechanosensing within the osteocyte lacunar-canalicular system

Bin Wang, Xiaohan Lai, Christopher Price, William R. Thompson, Wen Li, Tonima R. Quabili, Wei-Ju Tseng, Xiaowei Sherry Liu, Hong Zhang, Jun Pan, Catherine B. Kirn-Safran, Mary C. Farach-Carson, Liyun Wang

J Bone Miner Res. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: J Bone Miner Res. 2014 Apr; 29(4): 878–891. doi: 10.1002/jbmr.2105

PMCID:: PMC3962519

Article PDF–2.0M

Select item 384324311.

Synovial perlecan is required for osteophyte formation in knee osteoarthritis

Haruka Kaneko, Muneaki Ishijima, Ippei Futami, Naoki Tomikawa-Ichikawa, Keisuke Kosaki, Ryo Sadatsuki, Yoshihiko Yamada, Hisashi Kurosawa, Kazuo Kaneko, Eri Arikawa-Hirasawa

Matrix Biol. Author manuscript; available in PMC 2013 Nov 29.

Published in final edited form as: Matrix Biol. 2013 Apr 24; 32(0): 10.1016/j.matbio.2013.01.004. Published online 2013 Jan 20. doi: 10.1016/j.matbio.2013.01.004

PMCID:: PMC3843243

Article PDF–2.9M

Select item 327364612.

Oxygen-Glucose Deprivation (OGD) and Interleukin-1 (IL-1) Differentially Modulate Cathepsin B/L Mediated Generation of Neuroprotective Perlecan LG3 by Neurons

MAXIM G SAINI, GREGORY J BIX

Brain Res. Author manuscript; available in PMC 2013 Feb 15.

Published in final edited form as: Brain Res. 2012 Feb 15; 1438: 65–74. Published online 2011 Dec 20. doi: 10.1016/j.brainres.2011.12.027

PMCID:: PMC3273646

Article PDF–1.2M

Select item 317929413.

Perlecan/Hspg2 Deficiency Alters the Pericellular Space of the Lacunocanalicular System Surrounding Osteocytic Processes in Cortical Bone

William R Thompson, Shannon Modla, Brian J Grindel, Kirk J Czymmek, Catherine B Kirn-Safran, Liyun Wang, Randall L Duncan, Mary C Farach-Carson

J Bone Miner Res. 2011 Mar; 26(3): 618–629. Published online 2010 Sep 2. doi: 10.1002/jbmr.236

PMCID:: PMC3179294

Article PDF–501K

Select item 293921414.

Perlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition

Zhuo Xu, Naoki Ichikawa, Keisuke Kosaki, Yoshihiko Yamada, Takako Sasaki, Lynn Y. Sakai, Hisashi Kurosawa, Nobutaka Hattori, Eri Arikawa-Hirasawa

Matrix Biol. Author manuscript; available in PMC 2011 Jul 1.

Published in final edited form as: Matrix Biol. 2010 Jul; 29(6): 461–470. Published online 2010 Jun 9. doi: 10.1016/j.matbio.2010.06.001

PMCID:: PMC2939214

Article PDF–1.6M

Select item 276537715.

Heparan Sulfate in Perlecan Promotes Mouse Atherosclerosis: Roles in Lipid Permeability, Lipid Retention, and Smooth Muscle Cell Proliferation

Karin Tran-Lundmark, Phan-Kiet Tran, Gabrielle Paulsson-Berne, Vincent Fridén, Raija Soininen, Karl Tryggvason, Thomas N Wight, Michael G Kinsella, Jan Borén, Ulf Hedin

Circ Res. Author manuscript; available in PMC 2009 Oct 21.

Published in final edited form as: Circ Res. 2008 Jul 3; 103(1): 43–52. doi: 10.1161/CIRCRESAHA.108.172833