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Select item 77254681.

Mus81-Eme1–dependent aberrant processing of DNA replication intermediates in mitosis impairs genome integrity

Nicolás Luis Calzetta, Marina Alejandra González Besteiro, Vanesa Gottifredi

Sci Adv. 2020 Dec; 6(50): eabc8257. Published online 2020 Dec 9. doi: 10.1126/sciadv.abc8257

PMCID:: PMC7725468

Article PDF–4.9M

Select item 41939372.

Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substrates

Gwang Hyeon Gwon, Aera Jo, Kyuwon Baek, Kyeong Sik Jin, Yaoyao Fu, Jong-Bong Lee, YoungChang Kim, Yunje Cho

EMBO J. 2014 May 2; 33(9): 1061–1072. Published online 2014 Apr 14. doi: 10.1002/embj.201487820

PMCID:: PMC4193937

Article PDF–2.3M

Select item 22687863.

Cleavage mechanism of human Mus81–Eme1 acting on Holliday-junction structures

Ewan R. Taylor, Clare H. McGowan

Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10): 3757–3762. Published online 2008 Feb 29. doi: 10.1073/pnas.0710291105

PMCID:: PMC2268786

Article PDF–655K

Select item 13607464.

Haploinsufficiency of the Mus81–Eme1 endonuclease activates the intra-S-phase and G₂/M checkpoints and promotes rereplication in human cells

Takashi Hiyama, Mari Katsura, Takashi Yoshihara, Mari Ishida, Aiko Kinomura, Tetsuji Tonda, Toshimasa Asahara, Kiyoshi Miyagawa

Nucleic Acids Res. 2006; 34(3): 880–892. Published online 2006 Feb 2. doi: 10.1093/nar/gkj495

PMCID:: PMC1360746

Article PDF–703K

Select item 3292355.

RNA Interference Inhibition of Mus81 Reduces Mitotic Recombination in Human Cells

Veronique Blais, Hui Gao, Cherilyn A. Elwell, Michael N. Boddy, Pierre-Henri L. Gaillard, Paul Russell, Clare H. McGowan

Mol Biol Cell. 2004 Feb; 15(2): 552–562. doi: 10.1091/mbc.E03-08-0580

PMCID:: PMC329235

Article PDF–537K

Select item 31605796.

Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease

Raquel Domínguez-Kelly, Yusé Martín, Stephane Koundrioukoff, Marvin E. Tanenbaum, Veronique A.J. Smits, René H. Medema, Michelle Debatisse, Raimundo Freire

J Cell Biol. 2011 Aug 22; 194(4): 567–579. doi: 10.1083/jcb.201101047

PMCID:: PMC3160579

Article PDF–2.7M

Select item 31574037.

Structure-Specific DNA Endonuclease Mus81/Eme1 Generates DNA Damage Caused by Chk1 Inactivation

Josep V. Forment, Melanie Blasius, Ilaria Guerini, Stephen P. Jackson

PLoS One. 2011; 6(8): e23517. Published online 2011 Aug 17. doi: 10.1371/journal.pone.0023517

PMCID:: PMC3157403

Article PDF–1.1M

Select item 2754388.

Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells

Jacinth Abraham, Bénédicte Lemmers, M.Prakash Hande, Mary Ellen Moynahan, Charly Chahwan, Alberto Ciccia, Jeroen Essers, Katsuhiro Hanada, Richard Chahwan, Aik Kia Khaw, Peter McPherson, Amro Shehabeldin, Rob Laister, Cheryl Arrowsmith, Roland Kanaar, Stephen C. West, Maria Jasin, Razqallah Hakem

EMBO J. 2003 Nov 17; 22(22): 6137–6147. doi: 10.1093/emboj/cdg580

PMCID:: PMC275438

Article PDF–531K

Select item 69865639.

Pathway Analysis of Single-Nucleotide Polymorphisms Potentially Associated with Glioblastoma Multiforme Susceptibility Using Random Forests

Jeffrey S. Chang, Ru-Fang Yeh, John K. Wiencke, Joseph L. Wiemels, Ivan Smirnov, Alexander R. Pico, Tarik Tihan, Joe Patoka, Rei Miike, Jennette D. Sison, Terri Rice, Margaret R. Wrensch

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2020 Jan 28.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2008 Jun; 17(6): 1368–1373. doi: 10.1158/1055-9965.EPI-07-2830

PMCID:: PMC6986563

Article PDF–327K

Select item 600750910.

Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress

Anita Palma, Giusj Monia Pugliese, Ivana Murfuni, Veronica Marabitti, Eva Malacaria, Sara Rinalducci, Anna Minoprio, Massimo Sanchez, Filomena Mazzei, Lello Zolla, Annapaola Franchitto, Pietro Pichierri

Nucleic Acids Res. 2018 Jun 1; 46(10): 5109–5124. Published online 2018 Apr 18. doi: 10.1093/nar/gky280

PMCID:: PMC6007509

Article PDF–3.6M

Select item 425197911.

Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein

Nidhi Nair, Dennis Castor, Thomas Macartney, John Rouse

DNA Repair (Amst) 2014 Dec; 24: 131–137. doi: 10.1016/j.dnarep.2014.08.004

PMCID:: PMC4251979

Article PDF–2.2M

Select item 267566712.

Telomere recombination requires the MUS81 endonuclease

Sicong Zeng, Tao Xiang, Tej K. Pandita, Ignacio Gonzalez-Suarez, Susana Gonzalo, Curtis C. Harris, Qin Yang

Nat Cell Biol. Author manuscript; available in PMC 2009 Nov 1.

Published in final edited form as: Nat Cell Biol. 2009 May; 11(5): 616–623. Published online 2009 Apr 12. doi: 10.1038/ncb1867

PMCID:: PMC2675667

Article PDF–2.0M

Select item 258759513.

Human Rad54 protein stimulates human Mus81–Eme1 endonuclease

Olga M. Mazina, Alexander V. Mazin

Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47): 18249–18254. Published online 2008 Nov 18. doi: 10.1073/pnas.0807016105

PMCID:: PMC2587595

Article PDF–779K

Select item 233532914.

Crystal structure of the Mus81–Eme1 complex

Jeong Ho Chang, Jeong Joo Kim, Jung Min Choi, Jung Hoon Lee, Yunje Cho

Genes Dev. 2008 Apr 15; 22(8): 1093–1106. doi: 10.1101/gad.1618708

PMCID:: PMC2335329

Article PDF–1.0M

Select item 474871215.

UHRF1 Contributes to DNA Damage Repair as a Lesion Recognition Factor and Nuclease Scaffold

Yanyan Tian, Manikandan Paramasivam, Gargi Ghosal, Ding Chen, Xi Shen, Yaling huang, Shamima Akhter, Randy Legerski, Junjie Chen, Michael M Seidman, Jun Qin, Lei Li

Cell Rep. Author manuscript; available in PMC 2016 Feb 10.

Published in final edited form as: Cell Rep. 2015 Mar 31; 10(12): 1957–1966. Published online 2015 Mar 26. doi: 10.1016/j.celrep.2015.03.038

PMCID:: PMC4748712

Article PDF–1.8M

Select item 427134416.

How SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest

Marie-Lise Blondot, Loic Dragin, Hichem Lahouassa, Florence Margottin-Goguet

Retrovirology. 2014; 11: 117. Published online 2014 Dec 11. doi: 10.1186/s12977-014-0117-5

PMCID:: PMC4271344

Article PDF–891K

Select item 430110517.

G₂/M Cell Cycle Arrest Correlates with Primate Lentiviral Vpr Interaction with the SLX4 Complex

Gregory Berger, Madeleine Lawrence, Stephane Hué, Stuart J. D. Neil

J Virol. 2015 Jan 1; 89(1): 230–240. Prepublished online 2014 Oct 15. Published online 2014 Dec 16. doi: 10.1128/JVI.02307-14

PMCID:: PMC4301105

Article PDF–2.3M

Select item 420128818.

Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5′ flap DNA: basis of interstrand cross-link repair by FAN1

Gwang Hyeon Gwon, Youngran Kim, Yaqi Liu, Adam T. Watson, Aera Jo, Thomas J. Etheridge, Fenghua Yuan, Yanbin Zhang, YoungChang Kim, Anthony M. Carr, Yunje Cho

Genes Dev. 2014 Oct 15; 28(20): 2276–2290. doi: 10.1101/gad.248492.114