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Select item 109040481.

Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models

Katherine Oravecz-Wilson, Emma Lauder, Austin Taylor, Laure Maneix, Jeanine L. Van Nostrand, Yaping Sun, Lu Li, Dongchang Zhao, Chen Liu, Pavan Reddy

J Clin Invest. 2024 Mar 1; 134(5): e167369. Published online 2024 Mar 1. doi: 10.1172/JCI167369

PMCID:: PMC10904048

Abstract Article PDF–8.9M

Select item 107461792.

The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells

Jing Cheng, Yutong Wang, Lizheng Yin, Wenzhang Liang, Jing Zhang, Cuiqing Ma, Yu Zhang, Bo Liu, Jiachao Wang, Weiting Zhao, Miao Li, Lin Wei

mBio. 2023 Nov-Dec; 14(6): e01480-23. Published online 2023 Nov 1. doi: 10.1128/mbio.01480-23

PMCID:: PMC10746179

Abstract Article PDF–4.7M

Select item 103448673.

Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion

Yoshito Minami, Atsushi Hoshino, Yusuke Higuchi, Masahide Hamaguchi, Yusaku Kaneko, Yuhei Kirita, Shunta Taminishi, Toshiyuki Nishiji, Akiyuki Taruno, Michiaki Fukui, Zoltan Arany, Satoaki Matoba

Nat Commun. 2023; 14: 4084. Published online 2023 Jul 13. doi: 10.1038/s41467-023-39404-6

PMCID:: PMC10344867

Abstract Article PDF–11M

Select item 93974514.

Involvement of autophagy in exacerbation of eosinophilic airway inflammation in a murine model of obese asthma

Yuzo Suzuki, Yuya Aono, Norimichi Akiyama, Yasuoki Horiike, Hyogo Naoi, Ryo Horiguchi, Kiyoshi Shibata, Hironao Hozumi, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Naoki Inui, Takafumi Suda

Autophagy. 2022; 18(9): 2216–2228. Published online 2022 Jan 31. doi: 10.1080/15548627.2022.2025571

PMCID:: PMC9397451

Abstract Article PDF–4.5M

Select item 89424265.

Autophagy induction during stem cell activation plays a key role in salivary gland self-renewal

Idil Orhon, Cecilia Rocchi, Beatriz Villarejo-Zori, Paola Serrano Martinez, Mirjam Baanstra, Uilke Brouwer, Patricia Boya, Rob Coppes, Fulvio Reggiori

Autophagy. 2022; 18(2): 293–308. Published online 2021 May 19. doi: 10.1080/15548627.2021.1924036

PMCID:: PMC8942426

Abstract Article PDF–2.4M

Select item 89352206.

Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2

Zhimin Gao, Wei Yi, Junyuan Tang, Yuling Sun, Jianrong Huang, Tian Lan, Xiaoyan Dai, Suowen Xu, Zheng-Gen Jin, Xiaoqian Wu

Int J Biol Sci. 2022; 18(5): 2146–2162. Published online 2022 Feb 28. doi: 10.7150/ijbs.69116

PMCID:: PMC8935220

Abstract Article PDF–4.2M

Select item 89310857.

Autophagy impairment in liver CD11c⁺ cells promotes non-alcoholic fatty liver disease through production of IL-23

Lauriane Galle-Treger, Doumet Georges Helou, Christine Quach, Emily Howard, Benjamin P. Hurrell, German R. Aleman Muench, Pedram Shafiei-Jahani, Jacob D. Painter, Andrea Iorga, Lily Dara, Juliet Emamaullee, Lucy Golden-Mason, Hugo R. Rosen, Pejman Soroosh, Omid Akbari

Nat Commun. 2022; 13: 1440. Published online 2022 Mar 17. doi: 10.1038/s41467-022-29174-y

PMCID:: PMC8931085

Abstract Article PDF–3.6M

Select item 88141538.

Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice

Emmanouela Kallergi, Akrivi-Dimitra Daskalaki, Angeliki Kolaxi, Come Camus, Evangelia Ioannou, Valentina Mercaldo, Per Haberkant, Frank Stein, Kyriaki Sidiropoulou, Yannis Dalezios, Mikhail M. Savitski, Claudia Bagni, Daniel Choquet, Eric Hosy, Vassiliki Nikoletopoulou

Nat Commun. 2022; 13: 680. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28301-z

PMCID:: PMC8814153

Abstract Article PDF–5.0M

Select item 87266899.

Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism

Tzu-Yin Lee, Wan-Jung Lu, Chun A. Changou, Yuan-Chin Hsiung, Nguyen T. T. Trang, Cheng-Yang Lee, Tzu-Hao Chang, Thanasekaran Jayakumar, Cheng-Ying Hsieh, Chih-Hao Yang, Chao-Chien Chang, Ray-Jade Chen, Joen-Rong Sheu, Kuan-Hung Lin

Autophagy. 2021; 17(12): 4141–4158. Published online 2021 Apr 5. doi: 10.1080/15548627.2021.1904495

PMCID:: PMC8726689

Abstract Article PDF–3.8M

Select item 867277610.

α‐synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson’s disease

Hai‐Yue Tu, Bao‐Shi Yuan, Xiao‐Ou Hou, Xiao‐Jun Zhang, Chong‐Shuang Pei, Ya‐Ting Ma, Ya‐Ping Yang, Yi Fan, Zheng‐Hong Qin, Chun‐Feng Liu, Li‐Fang Hu

Aging Cell. 2021 Dec; 20(12): e13522. Published online 2021 Nov 22. doi: 10.1111/acel.13522

PMCID:: PMC8672776

Abstract Article PDF–2.8M

Select item 835459311.

Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice

Qian Huang, Yunhao Liu, Shiyang Zhang, Yi Tian Yap, Wei Li, David Zhang, Ahmad Gardner, Ling Zhang, Shizheng Song, Rex A Hess, Zhibing Zhang

Autophagy. 2021; 17(7): 1753–1767. Published online 2020 Jul 17. doi: 10.1080/15548627.2020.1783822

PMCID:: PMC8354593

Abstract Article PDF–10M

Select item 806566312.

High Dietary Phosphate Exacerbates and Acts Independently of Low Autophagy Activity in Pathological Cardiac Remodeling and Dysfunction

Mingjun Shi, Sierra Shepard, Zhiyong Zhou, Jenny Maique, Olivia Seli, Orson W. Moe, Ming Chang Hu

Cells. 2021 Apr; 10(4): 777. Published online 2021 Apr 1. doi: 10.3390/cells10040777

PMCID:: PMC8065663

Abstract Article PDF–4.4M

Select item 783711513.

Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum

Marijn Kuijpers, Gaga Kochlamazashvili, Alexander Stumpf, Dmytro Puchkov, Aarti Swaminathan, Max Thomas Lucht, Eberhard Krause, Tanja Maritzen, Dietmar Schmitz, Volker Haucke

Neuron. 2021 Jan 20; 109(2): 299–313.e9. doi: 10.1016/j.neuron.2020.10.005

Correction in:: Neuron. 2022 Feb 16; 110(4): 734.

PMCID:: PMC7837115

Abstract Article

Select item 684453014.

Autophagy protein ATG5 regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells

Dong Sun Oh, Heung Kyu Lee

Autophagy. 2019; 15(12): 2091–2106. Published online 2019 Apr 6. doi: 10.1080/15548627.2019.1596493

PMCID:: PMC6844530

Abstract Article PDF–5.2M

Select item 683986215.

Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation

Minori Kubota, Kazuki Kakimoto, Takatoshi Nakagawa, Eiko Koubayashi, Kei Nakazawa, Hideki Tawa, Yuki Hirata, Toshihiko Okada, Ken Kawakami, Akira Asai, Shuhei Hosomi, Toshihisa Takeuchi, Shinya Fukunishi, Takuya Inoue, Michio Asahi, Kazuhide Higuchi

PLoS One. 2019; 14(11): e0225066. Published online 2019 Nov 8. doi: 10.1371/journal.pone.0225066

PMCID:: PMC6839862

Abstract Article PDF–2.0M

Select item 663405316.

Reevaluation of Neurodegeneration in lurcher Mice: Constitutive Ion Fluxes Cause Cell Death with, Not by, Autophagy

Jun Nishiyama, Keiko Matsuda, Wataru Kakegawa, Nobuaki Yamada, Junko Motohashi, Noboru Mizushima, Michisuke Yuzaki

J Neurosci. 2010 Feb 10; 30(6): 2177–2187. doi: 10.1523/JNEUROSCI.6030-09.2010

PMCID:: PMC6634053

Abstract Article PDF–2.4M

Select item 642066517.

ATG5-mediated autophagy suppresses NF-κB signaling to limit epithelial inflammatory response to kidney injury

Xuan Peng, Yating Wang, Huiyan Li, Jinjin Fan, Jiani Shen, Xueqing Yu, Yi Zhou, Haiping Mao

Cell Death Dis. 2019 Apr; 10(4): 253. Published online 2019 Mar 15. doi: 10.1038/s41419-019-1483-7

PMCID:: PMC6420665

Abstract Article PDF–10M

Select item 628768718.

Thyroid hormone (T₃) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy

Winifred W. Yau, Brijesh K. Singh, Ronny Lesmana, Jin Zhou, Rohit A. Sinha, Kiraely A. Wong, Yajun Wu, Boon-Huat Bay, Shigeki Sugii, Lei Sun, Paul M. Yen

Autophagy. 2019; 15(1): 131–150. Published online 2018 Sep 13. doi: 10.1080/15548627.2018.1511263

PMCID:: PMC6287687

Abstract Article PDF–3.9M

Select item 612197019.

Impaired Autophagy in Intestinal Epithelial Cells Alters Gut Microbiota and Host Immune Responses

Lingyu Yang, Chao Liu, Wenjing Zhao, Chuan He, Jinmei Ding, Ronghua Dai, Ke Xu, Lu Xiao, Lingxiao Luo, Shuyun Liu, Wei Li, He Meng

Appl Environ Microbiol. 2018 Sep 15; 84(18): e00880-18. Prepublished online 2018 Jul 13. Published online 2018 Aug 31. doi: 10.1128/AEM.00880-18

PMCID:: PMC6121970

Abstract Article PDF–3.4M

Select item 602199420.

Blocking Autophagy in Oligodendrocytes Limits Functional Recovery after Spinal Cord Injury

Sujata Saraswat Ohri, Andrew N. Bankston, S. Ashley Mullins, Yu Liu, Kariena R. Andres, Jason E. Beare, Russell M. Howard, Darlene A. Burke, Amberly S. Riegler, Allison E. Smith, Michal Hetman, Scott R. Whittemore

J Neurosci. 2018 Jun 27; 38(26): 5900–5912. doi: 10.1523/JNEUROSCI.0679-17.2018