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Items: 1 to 20 of 79

1.
Three Human Pol ι Variants with Impaired Polymerase Activity Fail to Rescue H2O2 Sensitivity in POLI-Deficient Cells
Mina Yeom, Jin-Kyung Hong, Jae-Kwon Kim, F. Peter Guengerich, Jeong-Yun Choi
Chem Res Toxicol. Author manuscript; available in PMC 2022 Jul 15.
Published in final edited form as: Chem Res Toxicol. 2020 Aug 17; 33(8): 2120–2129. Published online 2020 Jul 23. doi: 10.1021/acs.chemrestox.0c00127
PMCID:
PMC9284323
ArticlePDF–970K
2.
DNA polymerase ι compensates for Fanconi anemia pathway deficiency by countering DNA replication stress
Rui Wang, Walter F. Lenoir, Chao Wang, Dan Su, Megan McLaughlin, Qianghua Hu, Xi Shen, Yanyan Tian, Naeh Klages-Mundt, Erica Lynn, Richard D. Wood, Junjie Chen, Traver Hart, Lei Li
Proc Natl Acad Sci U S A. 2020 Dec 29; 117(52): 33436–33445. Published online 2020 Dec 21. doi: 10.1073/pnas.2008821117
PMCID:
PMC7777187
ArticlePDF–1.9M
3.
Mysterious and fascinating: DNA polymerase ɩ remains enigmatic 20 years after its discovery
Alexandra Vaisman, Roger Woodgate
DNA Repair (Amst) Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2020 Sep; 93: 102914. doi: 10.1016/j.dnarep.2020.102914
PMCID:
PMC7586464
ArticlePDF–1.6M
4.
DNA polymerase ι: The long and the short of it!
Ekaterina G. Frank, Mary P. McLenigan, John P. McDonald, Donald Huston, Samantha Mead, Roger Woodgate
DNA Repair (Amst) Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: DNA Repair (Amst). 2017 Oct; 58: 47–51. Published online 2017 Aug 19. doi: 10.1016/j.dnarep.2017.08.006
PMCID:
PMC5616170
ArticlePDF–938K
5.
Identification of amino acid residues involved in the dRP-lyase activity of human Pol ι
Nataliya Miropolskaya, Ivan Petushkov, Andrey Kulbachinskiy, Alena V. Makarova
Sci Rep. 2017; 7: 10194. Published online 2017 Aug 31. doi: 10.1038/s41598-017-10668-5
PMCID:
PMC5579206
ArticlePDF–2.3M
6.
Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι
Rinku Jain, Jayati Roy Choudhury, Angeliki Buku, Robert E. Johnson, Louise Prakash, Satya Prakash, Aneel K. Aggarwal
Sci Rep. 2017; 7: 43904. Published online 2017 Mar 8. doi: 10.1038/srep43904
PMCID:
PMC5341039
ArticlePDF–1.1M
7.
DNA polymerase iota (Pol ι) promotes invasion and metastasis of esophageal squamous cell carcinoma
Shitao Zou, Zeng-Fu Shang, Biao Liu, Shuyu Zhang, Jinchang Wu, Min Huang, Wei-Qun Ding, Jundong Zhou
Oncotarget. 2016 May 31; 7(22): 32274–32285. Published online 2016 Apr 4. doi: 10.18632/oncotarget.8580
PMCID:
PMC5078012
ArticlePDF–8.5M
8.
Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase ι
Jeong-Yun Choi, Amritaj Patra, Mina Yeom, Young-Sam Lee, Qianqian Zhang, Martin Egli, F. Peter Guengerich
J Biol Chem. 2016 Sep 30; 291(40): 21063–21073. Published online 2016 Aug 23. doi: 10.1074/jbc.M116.748285
PMCID:
PMC5076516
ArticlePDF–1.9M
9.
Biochemical Analysis of Six Genetic Variants of Error-Prone Human DNA Polymerase ι Involved in Translesion DNA Synthesis
Jinsook Kim, Insil Song, Ara Jo, Joo-Ho Shin, Hana Cho, Robert L. Eoff, F. Peter Guengerich, Jeong-Yun Choi
Chem Res Toxicol. 2014 Oct 20; 27(10): 1837–1852. Published online 2014 Aug 27. doi: 10.1021/tx5002755
PMCID:
PMC4203391
ArticlePDF–5.0M
10.
The Steric Gate of DNA Polymerase ι Regulates Ribonucleotide Incorporation and Deoxyribonucleotide Fidelity
Katherine A. Donigan, Mary P. McLenigan, Wei Yang, Myron F. Goodman, Roger Woodgate
J Biol Chem. 2014 Mar 28; 289(13): 9136–9145. Published online 2014 Feb 14. doi: 10.1074/jbc.M113.545442
PMCID:
PMC3979402
ArticlePDF–2.1M
11.
Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota
Kevin N. Kirouac, Hong Ling
Proc Natl Acad Sci U S A. 2011 Feb 22; 108(8): 3210–3215. Published online 2011 Feb 7. doi: 10.1073/pnas.1013909108
PMCID:
PMC3044400
ArticlePDF–1.2M
12.
Replication across template T/U by human DNA polymerase-ι
Rinku Jain, Deepak T. Nair, Robert E. Johnson, Louise Prakash, Satya Prakash, Aneel K. Aggarwal
Structure. Author manuscript; available in PMC 2011 Jan 28.
Published in final edited form as: Structure. 2009 Jul 15; 17(7): 974–980. doi: 10.1016/j.str.2009.04.011
PMCID:
PMC3030472
ArticlePDF–1.0M
13.
Structural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase ι
Matthew G. Pence, Jeong-Yun Choi, Martin Egli, F. Peter Guengerich
J Biol Chem. 2010 Dec 24; 285(52): 40666–40672. Published online 2010 Oct 20. doi: 10.1074/jbc.M110.183665
PMCID:
PMC3003365
ArticlePDF–1.6M
14.
Influence of local sequence context on damaged base conformation in human DNA polymerase ι: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion
Kerry Donny-Clark, Suse Broyde
Nucleic Acids Res. 2009 Nov; 37(21): 7095–7109. Published online 2009 Sep 18. doi: 10.1093/nar/gkp745
PMCID:
PMC2790882
ArticlePDF–6.4M
15.
DNA synthesis across an abasic lesion by human DNA polymerase-ι
Deepak T. Nair, Robert E. Johnson, Louise Prakash, Satya Prakash, Aneel K. Aggarwal
Structure. Author manuscript; available in PMC 2010 Apr 15.
Published in final edited form as: Structure. 2009 Apr 15; 17(4): 530–537. doi: 10.1016/j.str.2009.02.015
PMCID:
PMC2703454
ArticlePDF–2.2M
16.
Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase ι
Kevin N Kirouac, Hong Ling
EMBO J. 2009 Jun 3; 28(11): 1644–1654. Published online 2009 May 14. doi: 10.1038/emboj.2009.122
PMCID:
PMC2693154
ArticlePDF–1.7M
17.
Lesion Bypass of N2-Ethylguanine by Human DNA Polymerase ι
Matthew G. Pence, Patrick Blans, Charles N. Zink, Thomas Hollis, James C. Fishbein, Fred W. Perrino
J Biol Chem. 2009 Jan 16; 284(3): 1732–1740. doi: 10.1074/jbc.M807296200
PMCID:
PMC2615510
ArticlePDF–591K
18.
Role of Hoogsteen Edge Hydrogen Bonding at Template Purines in Nucleotide Incorporation by Human DNA Polymerase ι
Robert E. Johnson, Lajos Haracska, Louise Prakash, Satya Prakash
Mol Cell Biol. 2006 Sep; 26(17): 6435–6441. doi: 10.1128/MCB.00851-06
PMCID:
PMC1592827
ArticlePDF–307K
19.
Human DNA Polymerase ι Promotes Replication through a Ring-Closed Minor-Groove Adduct That Adopts a syn Conformation in DNA
William T. Wolfle, Robert E. Johnson, Irina G. Minko, R. Stephen Lloyd, Satya Prakash, Louise Prakash
Mol Cell Biol. 2005 Oct; 25(19): 8748–8754. doi: 10.1128/MCB.25.19.8748-8754.2005
PMCID:
PMC1265759
ArticlePDF–189K
20.
A Single Domain in Human DNA Polymerase ι Mediates Interaction with PCNA: Implications for Translesion DNA Synthesis
Lajos Haracska, Narottam Acharya, Ildiko Unk, Robert E. Johnson, Jerard Hurwitz, Louise Prakash, Satya Prakash
Mol Cell Biol. 2005 Feb; 25(3): 1183–1190. doi: 10.1128/MCB.25.3.1183-1190.2005
PMCID:
PMC544020
ArticlePDF–329K

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