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Select item 91011261.

Rap1a Activity Elevated the Impact of Endogenous AGEs in Diabetic Collagen to Stimulate Increased Myofibroblast Transition and Oxidative Stress

Stephanie D. Burr, Christopher C. Dorroh, James A. Stewart, Jr.

Int J Mol Sci. 2022 May; 23(9): 4480. Published online 2022 Apr 19. doi: 10.3390/ijms23094480

PMCID:: PMC9101126

Article PDF–2.0M

Select item 88974362.

Rap1 prevents colitogenic Th17 cell expansion and facilitates Treg cell differentiation and distal TCR signaling

Sayaka Ishihara, Tsuyoshi Sato, Noriyuki Fujikado, Haruka Miyazaki, Takayuki Yoshimoto, Hiromitsu Yamamoto, Shinji Fukuda, Koko Katagiri

Commun Biol. 2022; 5: 206. Published online 2022 Mar 4. doi: 10.1038/s42003-022-03129-x

PMCID:: PMC8897436

Article PDF–3.0M

Select item 64478303.

Rap1 signal modulators control the maintenance of hematopoietic progenitors in bone marrow and adult long‐term hematopoiesis

Takahiko Imai, Hiroki Tanaka, Yoko Hamazaki, Nagahiro Minato

Cancer Sci. 2019 Apr; 110(4): 1317–1330. Published online 2019 Mar 18. doi: 10.1111/cas.13974

PMCID:: PMC6447830

Article PDF–1.4M

Select item 39130034.

Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction

Magdalena Chrzanowska-Wodnicka

Exp Cell Res. Author manuscript; available in PMC 2014 Sep 10.

Published in final edited form as: Exp Cell Res. 2013 Sep 10; 319(15): 2350–2359. Published online 2013 Aug 2. doi: 10.1016/j.yexcr.2013.07.022

PMCID:: PMC3913003

Article PDF–476K

Select item 34683455.

Cyclic AMP-Rap1A signaling activates RhoA to induce α_2c-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells

Selvi C. Jeyaraj, Nicholas T. Unger, Ali H. Eid, Srabani Mitra, N. Paul El-Dahdah, Lawrence A. Quilliam, Nicholas A. Flavahan, Maqsood A. Chotani

Am J Physiol Cell Physiol. 2012 Sep 1; 303(5): C499–C511. Published online 2012 May 23. doi: 10.1152/ajpcell.00461.2011

PMCID:: PMC3468345

Article

Select item 27932006.

Rap1 mediates protective effects of iloprost against ventilator-induced lung injury

Anna A. Birukova, Panfeng Fu, Junjie Xing, Konstantin G. Birukov

J Appl Physiol (1985) 2009 Dec; 107(6): 1900–1910. Published online 2009 Oct 22. doi: 10.1152/japplphysiol.00462.2009

PMCID:: PMC2793200

Article

Select item 13469077.

Rap1A-Deficient T and B Cells Show Impaired Integrin-Mediated Cell Adhesion

Marlena Duchniewicz, Tomasz Zemojtel, Mateusz Kolanczyk, Steffen Grossmann, Jürgen S. Scheele, Fried J. T. Zwartkruis

Mol Cell Biol. 2006 Jan; 26(2): 643–653. doi: 10.1128/MCB.26.2.643-653.2006

PMCID:: PMC1346907

Article PDF–646K

Select item 82039278.

Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population

Sayaka Ishihara, Tsuyoshi Sato, Risa Sugioka, Ryota Miwa, Haruka Saito, Ryota Sato, Hidehiro Fukuyama, Akihiko Nakajima, Satoshi Sawai, Ai Kotani, Koko Katagiri

Front Immunol. 2021; 12: 624419. Published online 2021 Jun 1. doi: 10.3389/fimmu.2021.624419

PMCID:: PMC8203927

Article PDF–3.6M

Select item 69110779.

Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy

Ekta Khattar, Kyaw Ze Ya Maung, Chen Li Chew, Arkasubhra Ghosh, Michelle Meng Huang Mok, Pei Lee, Jun Zhang, Wei Hong Jeff Chor, Gökhan Cildir, Chelsia Qiuxia Wang, Nur Khairiah Mohd-Ismail, Desmond Wai Loon Chin, Soo Chin Lee, Henry Yang, Yong-Jae Shin, Do-Hyun Nam, Liming Chen, Alan Prem Kumar, Lih Wen Deng, Masahito Ikawa, Jayantha Gunaratne, Motomi Osato, Vinay Tergaonkar

Nat Commun. 2019; 10: 5349. Published online 2019 Dec 13. doi: 10.1038/s41467-019-13082-9

PMCID:: PMC6911077

Article PDF–2.5M

Select item 671535910.

Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition

Kentaro Kaneko, Yukiko Fu, Hsiao-Yun Lin, Elizabeth L. Cordonier, Qianxing Mo, Yong Gao, Ting Yao, Jacqueline Naylor, Victor Howard, Kenji Saito, Pingwen Xu, Siyu S. Chen, Miao-Hsueh Chen, Yong Xu, Kevin W. Williams, Peter Ravn, Makoto Fukuda

J Clin Invest. 2019 Sep 3; 129(9): 3786–3791. Published online 2019 Aug 12. doi: 10.1172/JCI126107

PMCID:: PMC6715359

Article PDF–3.3M

Select item 667185211.

Enhanced Cortico-Amygdala Efficacy and Suppressed Fear in Absence of Rap1

Bing-Xing Pan, Francois Vautier, Wataru Ito, Vadim Y. Bolshakov, Alexei Morozov

J Neurosci. 2008 Feb 27; 28(9): 2089–2098. doi: 10.1523/JNEUROSCI.5156-07.2008

PMCID:: PMC6671852

Article PDF–844K

Select item 630798912.

Direct Rap1/Talin1 interaction regulates platelet and neutrophil integrin activity in mice

Thomas Bromberger, Sarah Klapproth, Ina Rohwedder, Liang Zhu, Laura Mittmann, Christoph A. Reichel, Markus Sperandio, Jun Qin, Markus Moser

Blood. 2018 Dec 27; 132(26): 2754–2762. Prepublished online 2018 Nov 15. doi: 10.1182/blood-2018-04-846766

PMCID:: PMC6307989

Article

Select item 618798913.

Mice lacking RAP1 show early onset and higher rates of DEN-induced hepatocellular carcinomas in female mice

Iole Ferrara-Romeo, Paula Martínez, Maria A. Blasco

PLoS One. 2018; 13(10): e0204909. Published online 2018 Oct 11. doi: 10.1371/journal.pone.0204909

PMCID:: PMC6187989

Article PDF–10M

Select item 581806214.

Rap1B promotes VEGF-induced endothelial permeability and is required for dynamic regulation of the endothelial barrier

Sribalaji Lakshmikanthan, Magdalena Sobczak, Sergio Li Calzi, Lynn Shaw, Maria B. Grant, Magdalena Chrzanowska-Wodnicka

J Cell Sci. 2018 Jan 1; 131(1): jcs207605. doi: 10.1242/jcs.207605

PMCID:: PMC5818062

Article

Select item 442805115.

Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function

Sribalaji Lakshmikanthan, Xiaodong Zheng, Yoshinori Nishijima, Magdalena Sobczak, Aniko Szabo, Jeannette Vasquez-Vivar, David X Zhang, Magdalena Chrzanowska-Wodnicka

EMBO Rep. 2015 May; 16(5): 628–637. Published online 2015 Mar 25. doi: 10.15252/embr.201439846