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Select item 46193631.

Prognostic significance of FAM3C in esophageal squamous cell carcinoma

Ying-Hui Zhu, Baozhu Zhang, Mengqing Li, Pinzhu Huang, Jian Sun, Jianhua Fu, Xin-Yuan Guan

Diagn Pathol. 2015; 10: 192. Published online 2015 Oct 24. doi: 10.1186/s13000-015-0424-8

PMCID:: PMC4619363

Abstract Article PDF–1007K

Select item 43030392.

Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen–urokinase plasminogen activator receptor system–regulated secretion during breast cancer progression

Agnes Csiszar, Betül Kutay, Silvia Wirth, Ulrike Schmidt, Sabine Macho-Maschler, Martin Schreiber, Memetcan Alacakaptan, Georg F Vogel, Karin Aumayr, Lukas A Huber, Hartmut Beug

Breast Cancer Res. 2014; 16: 433. Published online 2014 Sep 9. doi: 10.1186/s13058-014-0433-7

PMCID:: PMC4303039

Abstract Article PDF–3.1M

Select item 36824673.

A follow-up association study of two genetic variants for bone mineral density variation in Caucasians

L.-S. Zhang, H.-G. Hu, Y.-J. Liu, J. Li, P. Yu, F. Zhang, T.-L. Yang, Q. Tian, Y.-P. Zheng, Y. Guo, H.-W. Deng

Osteoporos Int. Author manuscript; available in PMC 2013 Jun 14.

Published in final edited form as: Osteoporos Int. 2012 Jul; 23(7): 1867–1875. Published online 2011 Dec 9. doi: 10.1007/s00198-011-1863-z

PMCID:: PMC3682467

Abstract Article PDF–568K

Select item 98304264.

FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites

Win Lwin Thuya, Li Ren Kong, Nicholas L. Syn, Ling-Wen Ding, Esther Sok Hwee Cheow, Regina Tong Xin Wong, Tingting Wang, Robby Miguel Wen-Jing Goh, Hongyan Song, Migara K. Jayasinghe, Minh TN Le, Jian Cheng Hu, Wei-Peng Yong, Soo-Chin Lee, Andrea Li-Ann Wong, Gautam Sethi, Huynh The Hung, Paul Chi-Lui Ho, Jean-Paul Thiery, Siu Kwan Sze, Tiannan Guo, Ross A. Soo, Henry Yang, Yaw Chyn Lim, Lingzhi Wang, Boon-Cher Goh

Theranostics. 2023; 13(2): 621–638. Published online 2023 Jan 1. doi: 10.7150/thno.72297

PMCID:: PMC9830426

Abstract Article PDF–9.8M

Select item 78909885.

The FAM3C locus that encodes interleukin-like EMT inducer (ILEI) is frequently co-amplified in MET-amplified cancers and contributes to invasiveness

Ulrike Schmidt, Gerwin Heller, Gerald Timelthaler, Petra Heffeter, Zsolt Somodi, Norbert Schweifer, Maria Sibilia, Walter Berger, Agnes Csiszar

J Exp Clin Cancer Res. 2021; 40: 69. Published online 2021 Feb 17. doi: 10.1186/s13046-021-01862-5

PMCID:: PMC7890988

Abstract Article PDF–7.6M

Select item 56024076.

The interleukin-like epithelial-mesenchymal transition inducer ILEI exhibits a non-interleukin-like fold and is active as a domain-swapped dimer

Anna M. Jansson, Agnes Csiszar, Joachim Maier, Ann-Christin Nyström, Elisabeth Ax, Patrik Johansson, Lovisa Holmberg Schiavone

J Biol Chem. 2017 Sep 15; 292(37): 15501–15511. Published online 2017 Jul 27. doi: 10.1074/jbc.M117.782904

PMCID:: PMC5602407

Abstract Article PDF–1.4M

Select item 54353467.

Interleukin-like EMT inducer regulates partial phenotype switching in MITF-low melanoma cell lines

Ken Noguchi, Annamarie C. Dalton, Breege V. Howley, Buckley J. McCall, Akihiro Yoshida, J. Alan Diehl, Philip H. Howe

PLoS One. 2017; 12(5): e0177830. Published online 2017 May 17. doi: 10.1371/journal.pone.0177830

PMCID:: PMC5435346

Abstract Article PDF–4.7M

Select item 79712208.

DEAH-box polypeptide 32 promotes hepatocellular carcinoma progression via activating the β-catenin pathway

Xiaoyun Hu, Guosheng Yuan, Qi Li, Jing Huang, Xiao Cheng, Jinzhang Chen

Ann Med. 2021; 53(1): 437–447. Published online 2021 Mar 17. doi: 10.1080/07853890.2021.1898674

PMCID:: PMC7971220

Abstract Article PDF–2.3M

Select item 65250209.

TGFβ promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis

Alec N. Woosley, Annamarie C. Dalton, George S. Hussey, Breege V. Howley, Bidyut K. Mohanty, Simon Grelet, Toros Dincman, Sean Bloos, Shaun K. Olsen, Philip H. Howe

Oncogene. Author manuscript; available in PMC 2019 Jul 28.

Published in final edited form as: Oncogene. 2019 May; 38(20): 3794–3811. Published online 2019 Jan 28. doi: 10.1038/s41388-019-0703-z

PMCID:: PMC6525020

Abstract Article PDF–2.9M

Select item 339037110.

Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus

Carolina Medina-Gomez, John P. Kemp, Karol Estrada, Joel Eriksson, Jeff Liu, Sjur Reppe, David M. Evans, Denise H. M. Heppe, Liesbeth Vandenput, Lizbeth Herrera, Susan M. Ring, Claudia J. Kruithof, Nicholas J. Timpson, M. Carola Zillikens, Ole K. Olstad, Hou-Feng Zheng, J. Brent Richards, Beate St. Pourcain, Albert Hofman, Vincent W. V. Jaddoe, George Davey Smith, Mattias Lorentzon, Kaare M. Gautvik, André G. Uitterlinden, Robert Brommage, Claes Ohlsson, Jonathan H. Tobias, Fernando Rivadeneira

PLoS Genet. 2012 Jul; 8(7): e1002718. Published online 2012 Jul 5. doi: 10.1371/journal.pgen.1002718

PMCID:: PMC3390371

Abstract Article PDF–1.0M

Select item 648450611.

FAM3C‐YY1 axis is essential for TGFβ‐promoted proliferation and migration of human breast cancer MDA‐MB‐231 cells via the activation of HSF1

Weili Yang, Biaoqi Feng, Yuhong Meng, Junpei Wang, Bin Geng, Qinghua Cui, Hongquan Zhang, Yang Yang, Jichun Yang

J Cell Mol Med. 2019 May; 23(5): 3464–3475. Published online 2019 Mar 19. doi: 10.1111/jcmm.14243

PMCID:: PMC6484506

Abstract Article PDF–1.9M

Select item 606517912.

Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1)

Ken Noguchi, Toros A. Dincman, Annamarie C. Dalton, Breege V. Howley, Buckley J. McCall, Bidyut K. Mohanty, Philip H. Howe

J Biol Chem. 2018 Jul 20; 293(29): 11401–11414. Published online 2018 Jun 5. doi: 10.1074/jbc.RA118.003616

PMCID:: PMC6065179

Abstract Article PDF–2.2M

Select item 406369713.

Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment

John P. Kemp, Carolina Medina-Gomez, Karol Estrada, Beate St Pourcain, Denise H. M. Heppe, Nicole M. Warrington, Ling Oei, Susan M. Ring, Claudia J. Kruithof, Nicholas J. Timpson, Lisa E. Wolber, Sjur Reppe, Kaare Gautvik, Elin Grundberg, Bing Ge, Bram van der Eerden, Jeroen van de Peppel, Matthew A. Hibbs, Cheryl L. Ackert-Bicknell, Kwangbom Choi, Daniel L. Koller, Michael J. Econs, Frances M. K. Williams, Tatiana Foroud, M. Carola Zillikens, Claes Ohlsson, Albert Hofman, André G. Uitterlinden, George Davey Smith, Vincent W. V. Jaddoe, Jonathan H. Tobias, Fernando Rivadeneira, David M. Evans

PLoS Genet. 2014 Jun; 10(6): e1004423. Published online 2014 Jun 19. doi: 10.1371/journal.pgen.1004423

PMCID:: PMC4063697

Abstract Article PDF–805K

Select item 842126714.

GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles

Lawrence G. Welch, Sew-Yeu Peak-Chew, Farida Begum, Tim J. Stevens, Sean Munro

J Cell Biol. 2021 Oct 4; 220(10): e202106115. Published online 2021 Sep 2. doi: 10.1083/jcb.202106115

PMCID:: PMC8421267

Abstract Article PDF–5.4M

Select item 44987015.

Lineage-Specific Gene Duplication and Loss in Human and Great Ape Evolution

Andrew Fortna, Young Kim, Erik MacLaren, Kriste Marshall, Gretchen Hahn, Lynne Meltesen, Matthew Brenton, Raquel Hink, Sonya Burgers, Tina Hernandez-Boussard, Anis Karimpour-Fard, Deborah Glueck, Loris McGavran, Rebecca Berry, Jonathan Pollack, James M Sikela

PLoS Biol. 2004 Jul; 2(7): e207. Published online 2004 Jul 13. doi: 10.1371/journal.pbio.0020207

PMCID:: PMC449870

Abstract Article PDF–1.1M

Select item 947545316.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 400459817.

Systematic identification of pathological lamin A interactors

Travis A. Dittmer, Nidhi Sahni, Nard Kubben, David E. Hill, Marc Vidal, Rebecca C. Burgess, Vassilis Roukos, Tom Misteli

Mol Biol Cell. 2014 May 1; 25(9): 1493–1510. doi: 10.1091/mbc.E14-02-0733

PMCID:: PMC4004598

Abstract Article PDF–3.5M

Select item 895660418.

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity

Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang

Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8

PMCID:: PMC8956604

Abstract Article PDF–3.9M

Select item 729072119.

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation

Danielle G. May, Kelsey L. Scott, Alexandre R. Campos, Kyle J. Roux

Cells. 2020 May; 9(5): 1070. Published online 2020 Apr 25. doi: 10.3390/cells9051070

PMCID:: PMC7290721

Abstract Article PDF–9.2M

Select item 952364520.

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis

Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han

Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6

PMCID:: PMC9523645

Abstract Article PDF–3.9M

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