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Items: 1 to 20 of 85

1.
The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28
Woo Jae Kim, Ben S. Wittner, Arnaud Amzallag, Brian W. Brannigan, David T. Ting, Sridhar Ramaswamy, Shyamala Maheswaran, Daniel A. Haber
J Biol Chem. 2015 Jun 5; 290(23): 14381–14390. Published online 2015 Apr 16. doi: 10.1074/jbc.M114.631945
PMCID:
PMC4505506
ArticlePDF–2.0M
2.
Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation
Zhuoyao Chen, Rafael M. Ioris, Stacey Richardson, Ava N. Van Ess, Iolanda Vendrell, Benedikt M. Kessler, Francesca M. Buffa, Luca Busino, Steven C. Clifford, Alex N. Bullock, Vincenzo D’Angiolella
Cell Death Differ. 2022 Oct; 29(10): 1955–1969. Published online 2022 Apr 4. doi: 10.1038/s41418-022-00983-4
PMCID:
PMC9525703
ArticlePDF–4.4M
3.
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis
Wendy Béguelin, Matt Teater, Micah D. Gearhart, María Teresa Calvo Fernández, Rebecca L. Goldstein, Mariano G. Cárdenas, Katerina Hatzi, Monica Rosen, Hao Shen, Connie M. Corcoran, Michelle Y. Hamline, Randy D. Gascoyne, Ross L. Levine, Omar Abdel-Wahab, Jonathan D. Licht, Rita Shaknovich, Olivier Elemento, Vivian J. Bardwell, Ari M. Melnick
Cancer Cell. Author manuscript; available in PMC 2017 Aug 8.
Published in final edited form as: Cancer Cell. 2016 Aug 8; 30(2): 197–213. doi: 10.1016/j.ccell.2016.07.006
PMCID:
PMC5000552
ArticlePDF–4.1M
4.
FBXO22 degrades nuclear PTEN to promote tumorigenesis
Meng-Kai Ge, Na Zhang, Li Xia, Cheng Zhang, Shuang-Shu Dong, Zhan-Ming Li, Yan Ji, Min-Hua Zheng, Jing Sun, Guo-Qiang Chen, Shao-Ming Shen
Nat Commun. 2020; 11: 1720. Published online 2020 Apr 6. doi: 10.1038/s41467-020-15578-1
PMCID:
PMC7136256
ArticlePDF–3.8M
5.
USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c
Ye Yao, Weijie Ma, Yonghua Guo, Yingyi Liu, Peng Xia, Xiaoling Wu, Yiran Chen, Kunlei Wang, Chengjie Mei, Ganggang Wang, Xiaomian Li, Zhonglin Zhang, Xi Chen, Yufeng Yuan
Oncogenesis. 2022 Dec; 11(1): 31. Published online 2022 Jun 2. doi: 10.1038/s41389-022-00404-8
Correction in:
Oncogenesis. 2023 Dec; 12(1): 27.
PMCID:
PMC9163188
ArticlePDF–8.2M
6.
DBIRD integrates alternative mRNA splicing with RNA polymerase II transcript elongation
Pierre Close, Philip East, A. Barbara Dirac-Svejstrup, Holger Hartmann, Mark Heron, Sarah Maslen, Alain Chariot, Johannes Söding, Mark Skehel, Jesper Q. Svejstrup
Nature. Author manuscript; available in PMC 2012 Oct 19.
Published in final edited form as: Nature. 2012 Mar 25; 484(7394): 386–389. Published online 2012 Mar 25. doi: 10.1038/nature10925
PMCID:
PMC3378035
ArticlePDF–1.2M
7.
Isoform-specific GSK3A activity is negatively correlated with human sperm motility
M J Freitas, J V Silva, C Brothag, B Regadas-Correia, M Fardilha, S Vijayaraghavan
Mol Hum Reprod. 2019 Apr; 25(4): 171–183. Published online 2019 Mar 2. doi: 10.1093/molehr/gaz009
PMCID:
PMC6440577
ArticlePDF–1.0M
8.
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy
M. Carolina Gallego Iradi, Judy C. Triplett, James D. Thomas, Rachel Davila, Anthony M. Crown, Hilda Brown, Jada Lewis, Maurice S. Swanson, Guilian Xu, Edgardo Rodriguez-Lebron, David R. Borchelt
Sci Rep. 2018; 8: 4049. Published online 2018 Mar 6. doi: 10.1038/s41598-018-21371-4
PMCID:
PMC5840295
ArticlePDF–1.8M
9.
Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
Jessica S. Elman, Thomas K. Ni, Kristen E. Mengwasser, Dexter Jin, Ania Wronski, Stephen J. Elledge, Charlotte Kuperwasser
Cell Rep. Author manuscript; available in PMC 2020 Jun 16.
Published in final edited form as: Cell Rep. 2019 Sep 24; 28(13): 3435–3449.e5. doi: 10.1016/j.celrep.2019.08.060
PMCID:
PMC7297508
ArticlePDF–2.4M
10.
A function for cyclin D1 in DNA repair uncovered by interactome analyses in human cancers
Siwanon Jirawatnotai, Yiduo Hu, Wojciech Michowski, Joshua E. Elias, Lisa Becks, Frederic Bienvenu, Agnieszka Zagozdzon, Tapasree Goswami, Yaoyu E. Wang, Alan B. Clark, Thomas A. Kunkel, Tanja van Harn, Bing Xia, Mick Correll, John Quackenbush, David M. Livingston, Steven P. Gygi, Piotr Sicinski
Nature. Author manuscript; available in PMC 2011 Dec 9.
Published in final edited form as: Nature. 2011 Jun 8; 474(7350): 230–234. Published online 2011 Jun 8. doi: 10.1038/nature10155
PMCID:
PMC3134411
ArticlePDF–2.1M
11.
KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
Ashish Kumar, Yuanzhi Lyu, Yuichi Yanagihashi, Chanikarn Chantarasrivong, Vladimir Majerciak, Michelle Salemi, Kang-Hsin Wang, Tomoki Inagaki, Frank Chuang, Ryan R. Davis, Clifford G. Tepper, Kazushi Nakano, Chie Izumiya, Michiko Shimoda, Ken-ichi Nakajima, Alexander Merleev, Zhi-Ming Zheng, Mel Campbell, Yoshihiro Izumiya
Cell Rep. Author manuscript; available in PMC 2022 May 31.
Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110788. doi: 10.1016/j.celrep.2022.110788
PMCID:
PMC9153692
ArticlePDF–3.0M
12.
RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O’Brien, Xiaozhe Xiong, Carino Gurjao, Maximilien Grandclaudon, Srivatsan Raghavan, Steven M. Corsello, Steven A. Carr, Namrata D. Udeshi, James Berstler, Ewa Sicinska, Kimmie Ng, Marios Giannakis
Nat Commun. 2022; 13: 3181. Published online 2022 Jun 8. doi: 10.1038/s41467-022-30794-7
PMCID:
PMC9177965
ArticlePDF–2.2M
13.
HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137
Fengwen Zhang, Paul D Bieniasz
eLife. 2020; 9: e55806. Published online 2020 Jun 15. doi: 10.7554/eLife.55806
PMCID:
PMC7295576
ArticlePDF–4.3M
14.
An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase
Zhifen Zhou, Yujing Li, Huimin Xu, Xiaowei Xie, Zibin He, Song Lin, Ruofei Li, Shouheng Jin, Jun Cui, Hai Hu, Feng Liu, Su Wu, Wenbin Ma, Zhou Songyang
iScience. 2022 Feb 18; 25(2): 103813. Published online 2022 Jan 25. doi: 10.1016/j.isci.2022.103813
PMCID:
PMC8844827
ArticlePDF–6.0M
15.
Phosphoproteome analysis of the human mitotic spindle
Marjaana Nousiainen, Herman H. W. Silljé, Guido Sauer, Erich A. Nigg, Roman Körner
Proc Natl Acad Sci U S A. 2006 Apr 4; 103(14): 5391–5396. Published online 2006 Mar 24. doi: 10.1073/pnas.0507066103
PMCID:
PMC1459365
ArticlePDF–370K
16.
The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1
Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi
J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162
PMCID:
PMC7948964
ArticlePDF–2.7M
17.
Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1
Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin
J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379
PMCID:
PMC9513271
ArticlePDF–2.7M
18.
TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2‐mediated degradation
Mi Chen, Shreyas Lingadahalli, Nitin Narwade, Kate Man Kei Lei, Shanshan Liu, Zuxianglan Zhao, Yimin Zheng, Qian Lu, Alexander Hin Ning Tang, Terence Chuen Wai Poon, Edwin Cheung
EMBO Rep. 2022 Aug; 23(8): e53468. Published online 2022 Jul 4. doi: 10.15252/embr.202153468
PMCID:
PMC9346471
ArticlePDF–5.2M
19.
Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins
Binkai Chi, Jeremy D. O’Connell, Tomohiro Yamazaki, Jaya Gangopadhyay, Steven P. Gygi, Robin Reed
Sci Rep. 2018; 8: 8755. Published online 2018 Jun 8. doi: 10.1038/s41598-018-27136-3
PMCID:
PMC5993797
ArticlePDF–2.9M
20.
PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase
Bikash Adhikari, Jelena Bozilovic, Mathias Diebold, Jessica Denise Schwarz, Julia Hofstetter, Martin Schröder, Marek Wanior, Ashwin Narain, Markus Vogt, Nevenka Dudvarski Stankovic, Apoorva Baluapuri, Lars Schönemann, Lorenz Eing, Pranjali Bhandare, Bernhard Kuster, Andreas Schlosser, Stephanie Heinzlmeir, Christoph Sotriffer, Stefan Knapp, Elmar Wolf
Nat Chem Biol. Author manuscript; available in PMC 2021 Apr 6.
Published in final edited form as: Nat Chem Biol. 2020 Nov 1; 16(11): 1179–1188. Published online 2020 Sep 28. doi: 10.1038/s41589-020-00652-y
PMCID:
PMC7610535
ArticlePDF–5.1M

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