Similar Compounds for PubChem Compound (Select 155903537) - PubChem Compound - NCBI

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Select item 1666117291.

an image of a chemical structure CID 166611729

BDBM585145; US11529356, Example 81

MW:: 408.500
MF:: C₂₂H₂₅FN₆O

IUPAC name:: 3-fluoro-4-[2-[(3R)-3-methylmorpholin-4-yl]-8-pyrazolidin-3-...

Create Date:: 2023-02-21

CID:: 166611729

Summary Similar Compounds Same Parent, Connectivity

Select item 1559035242.

an image of a chemical structure CID 155903524

BDBM459568; US10772893, Example 77

MW:: 393.500
MF:: C₂₂H₂₄FN₅O

IUPAC name:: (3R)-4-[4-(2-fluorophenyl)-8-pyrazolidin-3-yl-1,7-naphthyrid...

Create Date:: 2021-05-03

CID:: 155903524

Summary Similar Compounds Same Parent, Connectivity

Select item 1559035353.

an image of a chemical structure CID 155903535

BDBM459622; US10772893, Example 131

MW:: 408.500
MF:: C₂₂H₂₅FN₆O

IUPAC name:: 5-fluoro-2-[2-[(3R)-3-methylmorpholin-4-yl]-8-pyrazolidin-3-...

Create Date:: 2021-05-03

CID:: 155903535

Summary Similar Compounds Same Parent, Connectivity

Select item 1559035334.

an image of a chemical structure CID 155903533

BDBM459614; US10772893, Example 123

MW:: 411.400
MF:: C₂₂H₂₃F₂N₅O

IUPAC name:: (3R)-4-[4-(2,4-difluorophenyl)-8-pyrazolidin-3-yl-1,7-naphth...

Create Date:: 2021-05-03

CID:: 155903533

Summary Similar Compounds Same Parent, Connectivity

Select item 1559035225.

an image of a chemical structure CID 155903522

BDBM459566; US10772893, Example 75

MW:: 408.500
MF:: C₂₂H₂₅FN₆O

IUPAC name:: 4-fluoro-2-[2-[(3R)-3-methylmorpholin-4-yl]-8-pyrazolidin-3-...

Create Date:: 2021-05-03

CID:: 155903522

Summary Similar Compounds Same Parent, Connectivity

Select item 1559035196.

an image of a chemical structure CID 155903519

BDBM459563; US10772893, Example 72

MW:: 411.400
MF:: C₂₂H₂₃F₂N₅O

IUPAC name:: (3R)-4-[4-(2,3-difluorophenyl)-8-pyrazolidin-3-yl-1,7-naphth...

Create Date:: 2021-05-03

CID:: 155903519

Summary Similar Compounds Same Parent, Connectivity

Select item 1558835777.

an image of a chemical structure CID 155883577

US10729680, Example 7; BDBM453141; 4-(2,3-difluorophenyl)-5-methyl-2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridine

MW:: 425.500
MF:: C₂₃H₂₅F₂N₅O

IUPAC name:: (3R)-4-[4-(2,3-difluorophenyl)-5-methyl-8-pyrazolidin-3-yl-1...

Create Date:: 2021-04-14

CID:: 155883577

Summary Similar Compounds Same Parent, Connectivity

Select item 1351212808.

an image of a chemical structure CID 135121280

BDBM268281; US9549932, 314; 4-(4-fluorophenyl)-2-(morpholin- 4-yl)-8-(1H-pyrazol-5-yl)-1,7- naphthyridine

MW:: 379.400
MF:: C₂₁H₂₂FN₅O

IUPAC name:: 4-[4-(4-fluorophenyl)-8-pyrazolidin-3-yl-1,7-naphthyridin-2-...

Create Date:: 2018-12-04

CID:: 135121280

Summary Similar Compounds Same Parent, Connectivity

Select item 1351212649.

an image of a chemical structure CID 135121264

BDBM268265; US9549932, 298; 4-(3-fluorophenyl)-2-(morpholin- 4-yl)-8-(1H-pyrazol-5-yl)-1,7- naphthyridine

MW:: 379.400
MF:: C₂₁H₂₂FN₅O

IUPAC name:: 4-[4-(3-fluorophenyl)-8-pyrazolidin-3-yl-1,7-naphthyridin-2-...

Create Date:: 2018-12-04

CID:: 135121264

Summary Similar Compounds Same Parent, Connectivity

Select item 15590354510.

an image of a chemical structure CID 155903545

BDBM459654; US10772893, Example 163

MW:: 394.400
MF:: C₂₁H₂₃FN₆O

IUPAC name:: (3R)-4-[4-(5-fluoropyridin-2-yl)-8-pyrazolidin-3-yl-1,7-naph...

Create Date:: 2021-05-03

CID:: 155903545

Summary Similar Compounds Same Parent, Connectivity

Select item 15590354311.

an image of a chemical structure CID 155903543

BDBM459643; US10772893, Example 152

MW:: 394.400
MF:: C₂₁H₂₃FN₆O

IUPAC name:: (3R)-4-[4-(6-fluoropyridin-2-yl)-8-pyrazolidin-3-yl-1,7-naph...

Create Date:: 2021-05-03

CID:: 155903543

Summary Similar Compounds Same Parent, Connectivity

Select item 15590352812.

an image of a chemical structure CID 155903528

BDBM459578; US10772893, Example 87

MW:: 422.500
MF:: C₂₃H₂₇FN₆O

IUPAC name:: N-(4-fluorophenyl)-N-methyl-2-[(3R)-3-methylmorpholin-4-yl]-...

Create Date:: 2021-05-03

CID:: 155903528

Summary Similar Compounds Same Parent, Connectivity

Select item 15590352613.

an image of a chemical structure CID 155903526

BDBM459572; US10772893, Example 81

MW:: 477.600
MF:: C₂₆H₃₂FN₇O

IUPAC name:: (3R)-4-[4-(2-fluoro-4-piperazin-1-ylphenyl)-8-pyrazolidin-3-...

Create Date:: 2021-05-03

CID:: 155903526

Summary Similar Compounds Same Parent, Connectivity

Select item 15590351314.

an image of a chemical structure CID 155903513

BDBM459518; US10772893, Example 27

MW:: 375.500
MF:: C₂₂H₂₅N₅O

IUPAC name:: (3R)-3-methyl-4-(4-phenyl-8-pyrazolidin-3-yl-1,7-naphthyridi...

Create Date:: 2021-05-03

CID:: 155903513

Summary Similar Compounds Same Parent, Connectivity

Select item 15590350415.

an image of a chemical structure CID 155903504

BDBM459502; US10772893, Example 11

MW:: 361.400
MF:: C₂₁H₂₃N₅O

IUPAC name:: 4-(4-phenyl-8-pyrazolidin-3-yl-1,7-naphthyridin-2-yl)morphol...

Create Date:: 2021-05-03

CID:: 155903504

Summary Similar Compounds Same Parent, Connectivity

Select item 15588357616.

an image of a chemical structure CID 155883576

US10729680, Example 6; BDBM453140; 4-[2-fluoro-4-(piperazin-1-yl)phenyl]-5-methyl-2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridine

MW:: 491.600
MF:: C₂₇H₃₄FN₇O

IUPAC name:: (3R)-4-[4-(2-fluoro-4-piperazin-1-ylphenyl)-5-methyl-8-pyraz...

Create Date:: 2021-04-14

CID:: 155883576

Summary Similar Compounds Same Parent, Connectivity

Select item 15588357317.

an image of a chemical structure CID 155883573

US10729680, Example 3; BDBM453075; 4-(2-fluoropyridin-3-yl)-5-methyl-2-[(3R)-3-methylmorpholin-4-yl]-8-(1H-pyrazol-5-yl)-1,7-naphthyridine

MW:: 408.500
MF:: C₂₂H₂₅FN₆O

IUPAC name:: (3R)-4-[4-(2-fluoropyridin-3-yl)-5-methyl-8-pyrazolidin-3-yl...

Create Date:: 2021-04-14

CID:: 155883573

Summary Similar Compounds Same Parent, Connectivity

Select item 13512131218.

an image of a chemical structure CID 135121312

BDBM268395; US9549932, 431; N-(4-fluorophenyl)-N-methyl-2- (morpholin-4-yl)-8-(1H-pyrazol-5- yl)-1,7-naphthyridin-4-amine

MW:: 408.500
MF:: C₂₂H₂₅FN₆O

IUPAC name:: N-(4-fluorophenyl)-N-methyl-2-morpholin-4-yl-8-pyrazolidin-3...

Create Date:: 2018-12-04

CID:: 135121312

Summary Similar Compounds Same Parent, Connectivity

Select item 13512131119.

an image of a chemical structure CID 135121311

BDBM268391; US9549932, 427; N-(2-fluorophenyl)-N-methyl-2- (morpholin-4-yl)-8-(1H-pyrazol-5- yl)-1,7-naphthyridin-4-amine

MW:: 408.500
MF:: C₂₂H₂₅FN₆O

IUPAC name:: N-(2-fluorophenyl)-N-methyl-2-morpholin-4-yl-8-pyrazolidin-3...

Create Date:: 2018-12-04

CID:: 135121311

Summary Similar Compounds Same Parent, Connectivity

Select item 13512131020.

an image of a chemical structure CID 135121310

BDBM268388; US9549932, 424; N-(3-fluorophenyl)-N-methyl-2- (morpholin-4-yl)-8-(1H-pyrazol-5- yl)-1,7-naphthyridin-4-amine

MW:: 408.500
MF:: C₂₂H₂₅FN₆O

IUPAC name:: N-(3-fluorophenyl)-N-methyl-2-morpholin-4-yl-8-pyrazolidin-3...

Create Date:: 2018-12-04

CID:: 135121310

Summary Similar Compounds Same Parent, Connectivity

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Chemical Properties

Rule of 5 (141)
Compounds satisfied Lipinski's Rule of Five in evaluating druglikeness. Query: (-5:5[LOGP]) AND (0:500[MOLWT]) AND (0:5[HBDC]) AND (0:10[HBAC]).

BioActivity Experiments

BioAssays, Active (80)
Compounds identified as active in screening experiments

BioAssays, Tested (81)
Compounds identified as tested in screening experiments

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