BioAssays, activity concentration at/below 1 nM for PubChem Compound ( - PubChem BioAssay - NCBI

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Select item 13708151.

Inhibition of SERCA1a (unknown origin) ATPase activity

Source:: ChEMBL

Protein Target:: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Assay data:4 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 4 Tested

AID:: 1370815

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 12319402.

Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric analysis

Source:: ChEMBL

Protein Target:: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Assay data:3 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 13 Tested

AID:: 1231940

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 7424033.

SANGER: Inhibition of human NCI-H1299 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:45 Active, 3 Activity ≤ 1 nM, 28 Activity ≤ 1 µM, 113 Tested

AID:: 742403

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 7423984.

SANGER: Inhibition of human NCCIT cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:41 Active, 1 Activity ≤ 1 nM, 21 Activity ≤ 1 µM, 77 Tested

AID:: 742398

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 7423955.

SANGER: Inhibition of human NB69 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:68 Active, 2 Activity ≤ 1 nM, 43 Activity ≤ 1 µM, 137 Tested

AID:: 742395

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 7423866.

SANGER: Inhibition of human NALM-6 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:51 Active, 4 Activity ≤ 1 nM, 33 Activity ≤ 1 µM, 76 Tested

AID:: 742386

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 7423817.

SANGER: Inhibition of human MZ1-PC cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:69 Active, 3 Activity ≤ 1 nM, 36 Activity ≤ 1 µM, 137 Tested

AID:: 742381

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 7423538.

SANGER: Inhibition of human MES-SA cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:24 Active, 2 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 46 Tested

AID:: 742353

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 7423529.

SANGER: Inhibition of human MEL-JUSO cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:45 Active, 3 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 81 Tested

AID:: 742352

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74234410.

SANGER: Inhibition of human MDA-MB-231 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:39 Active, 1 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 98 Tested

AID:: 742344

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74234011.

SANGER: Inhibition of human MCF7 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:45 Active, 3 Activity ≤ 1 nM, 25 Activity ≤ 1 µM, 98 Tested

AID:: 742340

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74233912.

SANGER: Inhibition of human MC116 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:56 Active, 2 Activity ≤ 1 nM, 30 Activity ≤ 1 µM, 129 Tested

AID:: 742339

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74233313.

SANGER: Inhibition of human LXF-289 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:72 Active, 4 Activity ≤ 1 nM, 38 Activity ≤ 1 µM, 136 Tested

AID:: 742333

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74231614.

SANGER: Inhibition of human LCLC-97TM1 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:54 Active, 3 Activity ≤ 1 nM, 31 Activity ≤ 1 µM, 98 Tested

AID:: 742316

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74231515.

SANGER: Inhibition of human LCLC-103H cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:42 Active, 2 Activity ≤ 1 nM, 25 Activity ≤ 1 µM, 98 Tested

AID:: 742315

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74229916.

SANGER: Inhibition of human L-363 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:68 Active, 2 Activity ≤ 1 nM, 38 Activity ≤ 1 µM, 129 Tested

AID:: 742299

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74229817.

SANGER: Inhibition of human KYSE-70 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:40 Active, 1 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 98 Tested

AID:: 742298

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74229618.

SANGER: Inhibition of human KYSE-510 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:52 Active, 5 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 98 Tested

AID:: 742296

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74229519.

SANGER: Inhibition of human KYSE-450 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:44 Active, 3 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 98 Tested

AID:: 742295

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 74229420.

SANGER: Inhibition of human KYSE-410 cell growth in a cell viability assay.

Source:: ChEMBL

Assay data:43 Active, 1 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 98 Tested

AID:: 742294

Summary Compounds, Active Compounds, activity ≤ 1 µM

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BioActivity

Active Compounds (105)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (105)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (105)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (105)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (6)
BioAssays extracted from the literature
Other (99)
BioAssays deposited by other experimentalists

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