BioAssays, Active for PubChem Compound (Select 25227481) - PubChem BioAssay - NCBI

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Items: 9

Select item 4416881.

Cmax in Sprague-Dawley rat at 1 mg/kg, iv and 3 mg/kg, po

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 441688

Summary Compounds, Active PubMed Citation

Select item 4416842.

Inhibition of mouse ELOVL3

Source:: ChEMBL

Protein Target:: Elongation of very long chain fatty acids protein 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 441684

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4416823.

Inhibition of human ELOVL3

Source:: ChEMBL

Protein Target:: Elongation of very long chain fatty acids protein 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 441682

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4416804.

Inhibition of human ELOVL1

Source:: ChEMBL

Protein Target:: Elongation of very long chain fatty acids protein 1

Assay data:1 Active, 1 Tested

AID:: 441680

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 4416685.

Inhibition of ELOVL6 in mouse H2.35 cells assessed as elongation index

Source:: ChEMBL

Protein Target:: Elongation of very long chain fatty acids protein 6

Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested

AID:: 441668

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4416676.

Inhibition of mouse ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay

Source:: ChEMBL

Protein Target:: Elongation of very long chain fatty acids protein 6

Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested

AID:: 441667

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4416667.

Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay

Source:: ChEMBL

Protein Target:: Elongation of very long chain fatty acids protein 6

Assay data:29 Active, 23 Activity ≤ 1 µM, 32 Tested

AID:: 441666

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4416788.

Reduction of elongation index of total fatty acids in C57BL/6J mouse liver at 30 mg/kg, po twice daily for 3 days

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 441678

Summary Compounds, Active PubMed Citation

Select item 4416769.

Reduction of elongation index of liver lipids in C57BL/6J mouse at 1 mg/kg, po

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 441676

Summary Compounds, Active PubMed Citation

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BioActivity

Active Compounds (9)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (5)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (7)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (9)
BioAssays extracted from the literature

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BioAssays, Active for PubChem Compound (Select 25227481) (9)
PubChem BioAssay
Human gut genome
Human gut genome

biosample
Celiac disease: primary leukocytes
Celiac disease: primary leukocytes
Accession: GDS3646

GEO DataSets
Related DataSets for GEO Profiles (Select 63418529) (1)
GEO DataSets
Genome Links for Gene (Select 5069) (1)
Genome

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