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Inhibition of rat ROMK
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryRelated BioAssays by Target
thallium-flux assay from US Patent US11632953: "Method for controlling hematophagous or sap-feeding arthropods"
Assay data:7 Active, 9 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of ROMK (unknown origin) by Thallium Efflux assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of rat Kir1.1 expressed in HEK293 cells by electrophysiology assay
Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assay
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
Electrophysiology Assay from US Patent US10851108: "Substituted bicyclic heterocyclic compounds"
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibitory Activity Assay from US Patent US10759788: "Pharmaceutical uses of pyridine carboxamide derivatives"
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Electrophysiology Assay from US Patent US10723723: "Substituted bicycle heterocyclic derivatives useful as ROMK channel inhibitors"
Assay data:30 Active, 1 Activity ≤ 1 nM, 30 Activity ≤ 1 µM, 30 Tested
Thallium Flux Assay from US Patent US10723723: "Substituted bicycle heterocyclic derivatives useful as ROMK channel inhibitors"
Assay data:171 Active, 2 Activity ≤ 1 nM, 161 Activity ≤ 1 µM, 172 Tested
Thallium Flux Assay from US Patent US10513518: "Inhibitors of the renal outer medullary potassium channel"
Assay data:38 Active, 38 Activity ≤ 1 µM, 38 Tested
Electrophysiology Assay from US Patent US10501449: "Substituted nitrogen containing compounds"
Assay data:68 Active, 68 Activity ≤ 1 µM, 68 Tested
Biological Assay from US Patent US10364234: "Pyridinecarboxamide derivatives, preparation method thereof and pharmaceutical uses thereof"
Electrophysiology Assay from US Patent US9493474: "Inhibitors of the renal outer medullary potassium channel"
Assay data:26 Active, 24 Activity ≤ 1 µM, 26 Tested
Thallium Flux Assay from US Patent US9493474: "Inhibitors of the renal outer medullary potassium channel"
Assay data:34 Active, 31 Activity ≤ 1 µM, 34 Tested
Electrophysiology Assay from US Patent US9206199: "Inhibitors of the renal outer medullary potassium channel"
Assay data:17 Active, 17 Activity ≤ 1 µM, 17 Tested
Thallium Flux Assay from US Patent US9206199: "Inhibitors of the renal outer medullary potassium channel"
Assay data:192 Active, 192 Activity ≤ 1 µM, 192 Tested
Electrophysiology Assay from US Patent US9206198: "Inhibitors of the renal outer medullary potassium channel"
Assay data:29 Active, 29 Activity ≤ 1 µM, 29 Tested
Thallium Flux Assay from US Patent US9206198: "Inhibitors of the renal outer medullary potassium channel"
Assay data:76 Active, 76 Activity ≤ 1 µM, 76 Tested
Electrophysiology Assay from US Patent US9139585: "Inhibitors of the Renal Outer Medullary Potassium channel"
Assay data:49 Active, 48 Activity ≤ 1 µM, 49 Tested
Thallium Flux Assay from US Patent US9073882: "Inhibitors of the renal outer medullary potassium channel"
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
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