Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Competitive Inhibition Assay from US Patent US10632171: "Melanocortin receptor-specific peptides"
Assay data:130 Active, 12 Activity ≤ 1 nM, 125 Activity ≤ 1 µM, 130 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Radioligand Binding Assay from US Patent US9499482: "Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists"
Assay data:247 Active, 66 Activity ≤ 1 nM, 242 Activity ≤ 1 µM, 247 Tested
Binding Assay from US Patent US9073925: "Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof"
Assay data:10 Active, 10 Activity ≤ 1 µM, 10 Tested
Binding Assay from US Patent US8993765: "Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof"
Assay data:26 Active, 25 Activity ≤ 1 µM, 26 Tested
Binding Assay from US Patent US8933079: "Pyridone and pyridazinone derivatives as anti-obesity agents"
Assay data:119 Active, 119 Activity ≤ 1 µM, 119 Tested
Activation Assay from US Patent US8685958: "Therapeutic agents"
Assay data:16 Active, 16 Activity ≤ 1 µM, 16 Tested
Binding Assay from US Patent US8637501: "Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof"
Assay data:111 Active, 110 Activity ≤ 1 µM, 111 Tested
Binding Assay from US Patent US8629158: "Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof"
Assay data:40 Active, 40 Activity ≤ 1 µM, 40 Tested
Binding Assay from US Patent US8618299: "Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof"
Assay data:52 Active, 51 Activity ≤ 1 µM, 52 Tested
Radioligand Binding Assay from US Patent US8563583: "Pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists"
Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested
Calcium Mobilization Assay from US Patent US8552199: "Substituted indanes, method for the production thereof, and use thereof as drugs"
Assay data:24 Active, 22 Activity ≤ 1 µM, 24 Tested
Radioligand Binding Assay from Article 10.1016/j.bmcl.2009.04.147: "Identification of 2-aminobenzimidazoles as potent melanin-concentrating hormone 1-receptor (MCH1R) antagonists."
Assay data:17 Active, 18 Activity ≤ 1 µM, 18 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Radioligand Binding Assay (IC50) and Functional Assay (EC50/IC50) from Article 10.1016/j.bmcl.2009.04.147: "Identification of 2-aminobenzimidazoles as potent melanin-concentrating hormone 1-receptor (MCH1R) antagonists."
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Radioligand Binding Assay from US Patent US9586900: "Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists"
Assay data:120 Active, 1 Activity ≤ 1 nM, 107 Activity ≤ 1 µM, 121 Tested
Melanin-Concentrating Hormone MCH1 (SLC1) Eurofins-Panlabs radioligand binding assay
Assay data:2 Tested
SummaryRelated BioAssays by Target
PRESTO-Tango GPCRome screening (MCHR1R)
Assay data:1 Tested
MCH1 (h) CEREP ligand profiling
MCH1H_AGON Cerep selectivity data (BI)
Displacement of [125I]Tyr-S36057 from full length human recombinant SLC1 receptor expressed in CHO-K1 cells at 10 uM measured after 120 mins by radiometric scintillation analysis relative to control
SummaryPubMed CitationRelated BioAssays by Target
Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assay
Assay data:58 Active, 5 Activity ≤ 1 nM, 50 Activity ≤ 1 µM, 68 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on