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PI3K-gamma Scintillation Proximity Assay from US Patent US11926616: "Aminopyrazine diol compounds as PI3K-γ inhibitors"
Assay data:46 Active, 46 Activity ≤ 1 µM, 46 Tested
SummaryRelated BioAssays by Target
CDK2/Cyclin E1 HTRF Enzyme Activity Assay from US Patent US11919904: "Sulfonylamide compounds as CDK2 inhibitors"
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
In Vitro Test of Activities of Jak1, Jak2, Jak3, Tyk2 Kinases from US Patent US11919896: "[1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and use thereof"
Assay data:14 Active, 1 Activity ≤ 1 µM, 34 Tested
Assay data:34 Active, 22 Activity ≤ 1 µM, 34 Tested
NAMPT Enzyme Activating Effect (In Vitro Cell-Free Enzyme Assay from US Patent US11918568: "Fused ring compound having urea structure"
Assay data:55 Active, 55 Activity ≤ 1 µM, 55 Tested
NMN Fluorescence Biochemical Assay from US Patent US20240067631: "PYRAZOLE DERIVATIVES USEFUL AS NAMPT MODULATORS"
Assay data:89 Active, 28 Activity ≤ 1 µM, 145 Tested
SARS-CoV-2 3C-like (3CL) protease fluorescence assay (FRET) from US Patent US11912714: "Spiropyrrolidine derived antiviral agents"
Assay data:47 Active, 48 Activity ≤ 1 µM, 48 Tested
Luciferase assay from US Patent US11912681: "Crystalline and salt forms of PPAR agonist compounds"
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Mobility-Shift Assay from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"
Assay data:14 Active, 15 Activity ≤ 1 µM, 15 Tested
assay on hold
Summary
Evaluation of Kd Values from US Patent US20240059728: "NOVEL GALACTOSIDE INHIBITOR OF GALECTINS"
Assay data:6 Active, 3 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
Coupled Nucleotide Exchange Assay from US Patent US20240059703: "HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE"
Assay data:506 Active, 473 Activity ≤ 1 µM, 513 Tested
TBD from US Patent US20240059694: "COMPOUND CONTAINING 1,3-BENZODIOXOL STRUCTURE AND PREPARATION METHOD AND USE THEREOF"
Assay data:28 Active, 30 Activity ≤ 1 µM, 30 Tested
Assay data:30 Active, 30 Activity ≤ 1 µM, 30 Tested
Determination of Related Protease Inhibition from US Patent US20240059691: "ENZYME INHIBITORS"
Assay data:279 Active, 16 Activity ≤ 1 nM, 253 Activity ≤ 1 µM, 299 Tested
THR/RXR Heterodimer Assay for Thyroid Hormone Receptor Agonist Screening from US Patent US20240059682: "THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS"
Assay data:26 Active, 25 Activity ≤ 1 µM, 26 Tested
Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for Thyroid Hormone Receptor Agonist Screening from US Patent US20240059682: "THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
THR Reporter Gene Method from US Patent US20240059676: "THYROID HORMONE RECEPTOR b SELECTIVE AGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF"
Assay data:32 Active, 21 Activity ≤ 1 µM, 38 Tested
Biochemical QPCT and QPCTL Activity Assay from US Patent US20240059675: "PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN"
Assay data:36 Active, 8 Activity ≤ 1 nM, 36 Activity ≤ 1 µM, 36 Tested
In Vitro Kinase Binding Assay from US Patent US20240058459: "DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY TO THE EYE"
Assay data:3 Active, 2 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
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