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ATPase, Na+/K+, Heart, Pig Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of NA+/K+ ATPase (unknown origin) activity assessed as inhibition constant
Assay data:2 Tested
Inhibition of NA+/K+ ATPase (unknown origin) activity
Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of Beagle dog kidney NA+/K+ ATPase alpha 1 by measuring 32P-ATP hydrolysis at 0.0001 M preincubated for 10 mins followed by addition of 32P-ATP measured after 15 mins
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Beagle dog kidney NA+/K+ ATPase alpha 1 by measuring 32P-ATP hydrolysis preincubated for 10 mins followed by addition of 32P-ATP measured after 15 mins
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In Vitro Inhibition Activity from US Patent US11077128: "Selective inhibitors of Alpha2-containing isoforms of Na,K-ATPase and use thereof for reduction of intraocular pressure"
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Selective Inhibition Assays of Isolated Na,K-ATPase from US Patent US10668094: "Selective inhibitors of Alpha2-containing isoforms of Na,K-ATPase and use thereof for reduction of intraocular pressure"
Assay data:21 Active, 21 Activity ≤ 1 µM, 21 Tested
Na,K-ATPase Inhibition Assay from Article 10.1074/jbc.M114.557629: "Digoxin derivatives with enhanced selectivity for the a2 isoform of Na,K-ATPase: effects on intraocular pressure in rabbits."
Assay data:18 Active, 18 Activity ≤ 1 µM, 18 Tested
High Throughput Screening Assay from US Patent US9114126: "Na/K-ATPase ligands, ouabain antagonists, assays and uses thereof"
Assay data:1 Active, 10 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Proton Potassium-adenosine Triphosphatase (H+,K+-ATPase) Inhibitory Activity from US Patent US10308605: "Proton pump inhibitors"
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
ATPase (Na+/K+) Eurofins-Cerep enzyme and uptake assay
ATPase (Na+/K+) CEREP ligand profiling
ATP NA+/K+PI Eurofins-Panlabs selectivity data (BI)
ATPASE(NA/K) Cerep selectivity data (BI)
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