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Binding affinity to human CD1d expressed in human HeLa cells assessed as increase in IL-13 production at 10 uM to 10'-4 uM incubated overnight prior to iNKT MAD11 cells addition to CD1d-compound mixture and measured after 24 hrs by ELISA
Assay data:4 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to human CD1d expressed in human HeLa cells assessed as increase in IFNgamma production at 10 uM to 10'-4 uM incubated overnight prior to iNKT MAD11 cells addition to CD1d-compound mixture and measured after 6 hrs by ELISA
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Binding affinity to CD1D (unknown origin) assessed as increase in IL-2 production at 100 ng/ml preincubated for 16 hrs followed by Valpha-14 Vbeta-8.2 DN3A4-1.2(1.2) iNKT hybridoma cells addition to compound-CD1D mixture measured after 16 hrs by sandwich ELISA
Assay data:3 Active, 3 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Binding affinity to C1R-hCD1d expressed in human B cells assessed as increase in IFN-gamma/IL4 ratio in mouse iNKT cells upto 100 ng/ml after 36 hrs by ELISA
Assay data:5 Active, 5 Tested
Binding affinity to C1R-hCD1d expressed in human B cells assessed as change in IFN-gamma/IL4 ratio in human iNKT cells upto 100 ng/ml after 36 hrs by ELISA
Assay data:5 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to C1R-hCD1d expressed in human B cells assessed as activation of IL-4 release in human iNKT cells upto 100 ng/ml after 36 hrs by ELISA
Binding affinity to C1R-hCD1d expressed in human B cells assessed as activation of IFN-gamma release in human iNKT cells upto 100 ng/ml after 36 hrs by ELISA
Binding affinity to C1R-hCD1d expressed in human B cells assessed as increase in Th2 cytokine release in mouse iNKT cells upto 100 ng/ml after 36 hrs by ELISA
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